The Ron Clark Story follows an energetic young teacher named Ron Clark who leaves North Carolina to teach in a New York City public school. Through innovative teaching techniques and devotion to his students, Clark is able to make a remarkable difference in their lives. He helps one girl overcome challenges to become the top student, and offers an outlet for a boy's artistic talents. Despite falling ill, Clark continues working to raise his students' test scores, and they ultimately achieve the highest average in the school.