The overview of Leptin replacement therapy
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Leptin is a hormone that controls obesity and related health issues in human bodies. Scientists, for so many years, are engaged to discover how to use the leptin hormone to treat obesity.
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Leptin ppt
This document discusses leptin, a hormone that regulates body weight. It describes how leptin is produced in fat cells and acts in the hypothalamus to reduce appetite. Leptin resistance, where the body becomes insensitive to leptin, is a major factor in obesity. The document also outlines the physiological effects of leptin, factors that influence its expression, and potential leptin-targeting drugs for treating obesity and related conditions.
Biologically inactive leptin and early-onset extreme obesity
Obesity is one of the most common diseases in our society. Sedentarism and fatty diet are involved in most of cases as the etiology of this disease and most of the times treatment is focused in these problems, but there are some cases in which obesity appears in an early age and parents have a normal weight. For this reason scientists have made several studies trying to find a explanation to this, for instance genetic mutations as a etiology of this condition. Mutations in leptin gen are involved in etiology of early onset extreme obesity.
Obesity and leptin...
1) Leptin is a hormone produced mainly by adipose tissue that plays a key role in regulating appetite and energy expenditure.
2) It acts in the hypothalamus by binding to leptin receptors and stimulating anorexigenic peptides while inhibiting hunger signals like neuropeptide Y.
3) Mutations that cause leptin deficiency or leptin receptor deficiency result in obesity that can be treated with replacement of leptin or combined leptin and amylin therapy, demonstrating the important role of leptin in regulating body weight.
Occupational Therapy Leptin & Obesity
Leptin is a hormone produced by adipose tissue that regulates appetite and energy homeostasis in the brain. It also plays roles in immune function and inflammation. In obesity, leptin resistance develops where the brain is less responsive to leptin's signals to decrease food intake. High leptin levels in obesity are associated with chronic low-grade inflammation. Leptin signaling in the immune system regulates both innate and adaptive immune responses.
Leptin
Leptin is a hormone that regulates appetite and energy expenditure. It is produced in fat cells and signals the brain to reduce food intake and increase burning of calories. Obesity develops when leptin resistance occurs, where high leptin levels fail to properly regulate weight. Leptin resistance has many contributing factors including impaired leptin transport to the brain, attenuation of leptin signaling pathways in the brain, endoplasmic reticulum stress, deficiencies in autophagy, and inflammation in fat tissue. Further research is still needed to fully understand how leptin resistance develops and how to overcome it for obesity treatment.
Effect of Leptin On Obesity
Obesity is caused by excessive food intake and lack of physical activity leading to excess body fat accumulation. Leptin is a hormone that regulates appetite and weight by binding to leptin receptors in the brain. In obesity, leptin resistance develops where leptin is unable to properly signal in the brain despite high leptin levels. Mechanisms of leptin resistance include reduced leptin transport to the brain, impaired leptin signaling in the hypothalamus, and induction of SOCS3 which inhibits leptin signaling. Strategies to overcome leptin resistance include caloric restriction, exercise, and drugs that inhibit SOCS3 or increase leptin receptor expression to improve leptin signaling
Role of Leptin in Obesity
Leptin is a hormone secreted by adipose tissue that regulates food intake and energy expenditure. It works through the hypothalamus, stimulating neurons that reduce appetite and increase metabolism, while inhibiting neurons that induce feeding. Conditions like lesions in the hypothalamus or leptin resistance can disrupt this system and lead to obesity or anorexia. Obese individuals often have high leptin levels but are resistant to its effects, causing further weight gain despite the body's attempts to reduce food intake through leptin signaling.
obesity final
This document defines obesity and discusses its epidemiology, regulation, neurohumoral factors, and genetics. Some key points:
- Obesity is defined as excess adipose tissue and a BMI ≥30. It is more common in women and prevalence is increasing globally.
- The hypothalamus regulates appetite through centers that stimulate (lateral) or inhibit (ventromedial) eating. Leptin, adipokines, gut hormones, and pancreatic hormones also influence appetite.
- Genetic factors contribute to obesity risk, as seen in family and twin studies. Rare genetic syndromes like Prader-Willi can also cause obesity.
- Leptin normally inhibits appetite but leptin
Recommended
Leptin ppt
This document discusses leptin, a hormone that regulates body weight. It describes how leptin is produced in fat cells and acts in the hypothalamus to reduce appetite. Leptin resistance, where the body becomes insensitive to leptin, is a major factor in obesity. The document also outlines the physiological effects of leptin, factors that influence its expression, and potential leptin-targeting drugs for treating obesity and related conditions.
Biologically inactive leptin and early-onset extreme obesity
Obesity is one of the most common diseases in our society. Sedentarism and fatty diet are involved in most of cases as the etiology of this disease and most of the times treatment is focused in these problems, but there are some cases in which obesity appears in an early age and parents have a normal weight. For this reason scientists have made several studies trying to find a explanation to this, for instance genetic mutations as a etiology of this condition. Mutations in leptin gen are involved in etiology of early onset extreme obesity.
Obesity and leptin...
1) Leptin is a hormone produced mainly by adipose tissue that plays a key role in regulating appetite and energy expenditure.
2) It acts in the hypothalamus by binding to leptin receptors and stimulating anorexigenic peptides while inhibiting hunger signals like neuropeptide Y.
3) Mutations that cause leptin deficiency or leptin receptor deficiency result in obesity that can be treated with replacement of leptin or combined leptin and amylin therapy, demonstrating the important role of leptin in regulating body weight.
Occupational Therapy Leptin & Obesity
Leptin is a hormone produced by adipose tissue that regulates appetite and energy homeostasis in the brain. It also plays roles in immune function and inflammation. In obesity, leptin resistance develops where the brain is less responsive to leptin's signals to decrease food intake. High leptin levels in obesity are associated with chronic low-grade inflammation. Leptin signaling in the immune system regulates both innate and adaptive immune responses.
Leptin
Leptin is a hormone that regulates appetite and energy expenditure. It is produced in fat cells and signals the brain to reduce food intake and increase burning of calories. Obesity develops when leptin resistance occurs, where high leptin levels fail to properly regulate weight. Leptin resistance has many contributing factors including impaired leptin transport to the brain, attenuation of leptin signaling pathways in the brain, endoplasmic reticulum stress, deficiencies in autophagy, and inflammation in fat tissue. Further research is still needed to fully understand how leptin resistance develops and how to overcome it for obesity treatment.
Effect of Leptin On Obesity
Obesity is caused by excessive food intake and lack of physical activity leading to excess body fat accumulation. Leptin is a hormone that regulates appetite and weight by binding to leptin receptors in the brain. In obesity, leptin resistance develops where leptin is unable to properly signal in the brain despite high leptin levels. Mechanisms of leptin resistance include reduced leptin transport to the brain, impaired leptin signaling in the hypothalamus, and induction of SOCS3 which inhibits leptin signaling. Strategies to overcome leptin resistance include caloric restriction, exercise, and drugs that inhibit SOCS3 or increase leptin receptor expression to improve leptin signaling
Role of Leptin in Obesity
Leptin is a hormone secreted by adipose tissue that regulates food intake and energy expenditure. It works through the hypothalamus, stimulating neurons that reduce appetite and increase metabolism, while inhibiting neurons that induce feeding. Conditions like lesions in the hypothalamus or leptin resistance can disrupt this system and lead to obesity or anorexia. Obese individuals often have high leptin levels but are resistant to its effects, causing further weight gain despite the body's attempts to reduce food intake through leptin signaling.
obesity final
This document defines obesity and discusses its epidemiology, regulation, neurohumoral factors, and genetics. Some key points:
- Obesity is defined as excess adipose tissue and a BMI ≥30. It is more common in women and prevalence is increasing globally.
- The hypothalamus regulates appetite through centers that stimulate (lateral) or inhibit (ventromedial) eating. Leptin, adipokines, gut hormones, and pancreatic hormones also influence appetite.
- Genetic factors contribute to obesity risk, as seen in family and twin studies. Rare genetic syndromes like Prader-Willi can also cause obesity.
- Leptin normally inhibits appetite but leptin
A Study On Meeting Receptor
Here are the key points about dopamine:
- Dopamine is a neurotransmitter produced in the substantia nigra and ventral tegmental area of the basal ganglia in the brain.
- Its production involves a two-step process where the amino acid tyrosine first reacts with the enzyme tyrosine hydroxylase to produce L-Dopa.
- L-Dopa then reacts with the enzyme L-Dopa decarboxylase to finally produce dopamine.
- Dopamine provides both excitatory and inhibitory responses by acting on axon networks in the brain.
- It plays an important role in processes like reward, motivation, pleasure, and motor control by signaling between neurons.
Adipokines
This document discusses adipokines, hormones secreted by adipose tissue. It focuses on leptin, adiponectin, resistin, and other adipokines. Leptin regulates appetite and metabolism. Its levels correlate with fat mass. Adiponectin reduces inflammation and insulin resistance. Resistin causes insulin resistance. The document examines the functions of these adipokines in processes like fertility, pregnancy, puberty, angiogenesis, and atherosclerosis. It provides details on receptors, mechanisms of action, and the roles of adipokines in conditions such as obesity and insulin resistance.
Obesity ppt 2
This document summarizes several research papers on obesity and related diseases like diabetes. It discusses how obesity can cause type 2 diabetes through mechanisms like endoplasmic reticulum stress from overnutrition, suppression of insulin receptor substrates, and increased levels of the hormone resistin. One study found that visceral fat may produce a protein called visfatin that acts as an insulin mimic. Genetic factors like mutations in genes related to the leptin and melanocortin pathways can also cause monogenic forms of obesity.
Polimorfismos e obesidade
Expositor: Efrain Olszewer.
III Congreso mundial de medicina y nutrición ortomolecular e integrativa
Polimorfismos y obesidad
This document discusses several genes related to obesity, including:
- FTO gene, which is associated with increased obesity risk in humans. Variants of this gene can act as a switch for IRX3 activity.
- GHRL gene which encodes ghrelin, a hormone that increases hunger. Variants in this gene have been linked to obesity.
- LEP and LEPR genes which encode leptin, a hormone that suppresses appetite, and the leptin receptor. Variants in these genes have been linked to obesity and leptin resistance.
- MC4R gene which encodes a receptor involved in appetite regulation. Variants in this gene are a common cause of inherited obesity.
Final Report Anne Cox
This document summarizes research on the expression of the hepatocyte nuclear factor 4 alpha (HNF4A) gene in the livers of Burmese pythons after feeding. The key findings are:
1) HNF4A expression doubles in python liver tissue 1 day after feeding, suggesting it plays a role in bile acid transport and fat digestion similar to humans.
2) HNF4A helps sequester bile acids in liver cells, likely to aid in digestion of large meals. Its expression returns to normal levels by 3 days post-feeding.
3) Real-time PCR was used to analyze HNF4A expression at different timepoints after feeding. Primers were designed and validated
Obesity Awareness
Dr. Sharanya Rajan's document defines obesity and discusses its epidemiology. Key points include:
- Obesity is defined as a BMI ≥ 30 and is caused by an imbalance between energy intake and expenditure.
- Over 1.6 billion adults are overweight globally, with 400 million obese. Obesity is more common in women and increasingly affects poorer populations.
- Hypothalamic and genetic factors contribute to obesity development. Conditions like Prader-Willi syndrome, leptin/leptin receptor deficiencies, and POMC/MC4R mutations can cause monogenic obesity.
- Adipokines like leptin and resistin, as well as gut and pancreatic hormones, help regulate
The+Endocrine+System
The document summarizes key aspects of the endocrine system, including:
1) It coordinates slower responses to stimuli compared to the nervous system and regulates growth and homeostasis.
2) Hormones can be protein or steroid based, with different solubility and receptor interaction properties.
3) Feedback loops, second messengers, glands, and hormone interactions are described, highlighting control of processes like metabolism and development.
4) The hypothalamus, pituitary and thyroid glands interact in regulatory pathways, while other glands like the pancreas and gonads produce hormones controlling functions like blood sugar and sexual development.
The+ Endocrine+ System
The document summarizes key aspects of the endocrine system, including:
1) It coordinates slower responses to stimuli compared to the nervous system and regulates growth and homeostasis.
2) Hormones can be protein or steroid based, with different solubility and receptor interaction properties.
3) Feedback loops, second messengers, glands, and hormone interactions are described, highlighting control of processes like metabolism and development.
4) The hypothalamus, pituitary and thyroid glands interact in regulatory pathways, while other glands like the pancreas and gonads produce hormones controlling functions like blood sugar and sexual development.
Chapter+45
Both the nervous system and endocrine system regulate physiological processes, though they differ in their communication methods and response times. The endocrine system uses hormones like epinephrine, while the nervous system uses neurotransmitters. Key endocrine glands include the hypothalamus, pituitary gland, thyroid gland, adrenal glands, pancreas, ovaries/testes, and thymus gland. Hormone signaling occurs via models like the steroid model or protein model and involves signal transduction pathways.
Chapter+45
Both the nervous system and endocrine system regulate physiological processes, though they differ in their communication methods and response times. The endocrine system uses hormones like epinephrine, while the nervous system uses neurotransmitters. Key endocrine glands include the hypothalamus, pituitary gland, thyroid gland, adrenal glands, pancreas, ovaries/testes, and thymus gland. Hormone signaling occurs via models like the protein/steroid models and involves signal transduction pathways.
Thyroid hormones
The thyroid gland produces thyroid hormones T3 and T4 which regulate metabolism. T4 is the major hormone produced and is converted to the more active T3 in tissues. Their production involves iodine uptake and coupling of tyrosine residues in thyroglobulin. T3 and T4 act through nuclear receptors to regulate gene expression and increase metabolism. Disorders include hypothyroidism with low hormone levels and hyperthyroidism with excessive levels leading to increased metabolism. Tests are used to evaluate thyroid function and hormone levels.
obesity.pptx
This document defines obesity and discusses the regulation of appetite and factors involved in obesity. It provides epidemiological data on obesity rates globally and in India. Several genetic syndromes and monogenic causes of obesity are described, including deficiencies in leptin, the leptin receptor, POMC, and prohormone convertase 1, which all result in hyperphagia and severe early-onset obesity. Twin and adoption studies support a strong genetic component to obesity.
PROJECT PROPOSAL
This 3-sentence summary provides the key details about the document:
The document proposes a research project to identify inhibitors of the hormone-sensitive lipase (HSL) enzyme from food sources to control lipolysis and regulate fatty acid levels for managing obesity and preventing diabetes. The project would express and purify HSL, screen food extracts for inhibitors, test efficacy in cell and animal studies, and analyze effects on metabolic parameters and toxicity to identify potential HSL-inhibiting compounds for treating insulin resistance. The goal is to develop food-based therapies for obesity and diabetes by controlling HSL activity and fatty acid levels.
lipid droplet.pptx
Lipid droplets are organelles found in nearly all cell types that consist of a neutral lipid core surrounded by a phospholipid monolayer. They function in the storage, transport, and metabolism of lipids. Lipid droplets form through a budding process from the endoplasmic reticulum, facilitated by proteins embedded in the ER membrane. Perilipin proteins then coat the surface of lipid droplets, protecting the stored lipids from degradation. During periods of energy demand, phosphorylation of perilipin allows for lipase-mediated breakdown of lipids from the droplets. In addition to energy storage, lipid droplets are involved in other processes like protein storage and maturation, vitamin storage, and stress response.
Know Latest Hiranandani Hospital Powai News.pdf
As Mumbai's premier kidney transplant and donation center, L H Hiranandani Hospital Powai is not just a medical facility; it's a beacon of hope where cutting-edge science meets compassionate care, transforming lives and redefining the standards of kidney health in India.
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A Study On Meeting Receptor
Here are the key points about dopamine:
- Dopamine is a neurotransmitter produced in the substantia nigra and ventral tegmental area of the basal ganglia in the brain.
- Its production involves a two-step process where the amino acid tyrosine first reacts with the enzyme tyrosine hydroxylase to produce L-Dopa.
- L-Dopa then reacts with the enzyme L-Dopa decarboxylase to finally produce dopamine.
- Dopamine provides both excitatory and inhibitory responses by acting on axon networks in the brain.
- It plays an important role in processes like reward, motivation, pleasure, and motor control by signaling between neurons.
Adipokines
This document discusses adipokines, hormones secreted by adipose tissue. It focuses on leptin, adiponectin, resistin, and other adipokines. Leptin regulates appetite and metabolism. Its levels correlate with fat mass. Adiponectin reduces inflammation and insulin resistance. Resistin causes insulin resistance. The document examines the functions of these adipokines in processes like fertility, pregnancy, puberty, angiogenesis, and atherosclerosis. It provides details on receptors, mechanisms of action, and the roles of adipokines in conditions such as obesity and insulin resistance.
Obesity ppt 2
This document summarizes several research papers on obesity and related diseases like diabetes. It discusses how obesity can cause type 2 diabetes through mechanisms like endoplasmic reticulum stress from overnutrition, suppression of insulin receptor substrates, and increased levels of the hormone resistin. One study found that visceral fat may produce a protein called visfatin that acts as an insulin mimic. Genetic factors like mutations in genes related to the leptin and melanocortin pathways can also cause monogenic forms of obesity.
Polimorfismos e obesidade
Expositor: Efrain Olszewer.
III Congreso mundial de medicina y nutrición ortomolecular e integrativa
Polimorfismos y obesidad
This document discusses several genes related to obesity, including:
- FTO gene, which is associated with increased obesity risk in humans. Variants of this gene can act as a switch for IRX3 activity.
- GHRL gene which encodes ghrelin, a hormone that increases hunger. Variants in this gene have been linked to obesity.
- LEP and LEPR genes which encode leptin, a hormone that suppresses appetite, and the leptin receptor. Variants in these genes have been linked to obesity and leptin resistance.
- MC4R gene which encodes a receptor involved in appetite regulation. Variants in this gene are a common cause of inherited obesity.
Final Report Anne Cox
This document summarizes research on the expression of the hepatocyte nuclear factor 4 alpha (HNF4A) gene in the livers of Burmese pythons after feeding. The key findings are:
1) HNF4A expression doubles in python liver tissue 1 day after feeding, suggesting it plays a role in bile acid transport and fat digestion similar to humans.
2) HNF4A helps sequester bile acids in liver cells, likely to aid in digestion of large meals. Its expression returns to normal levels by 3 days post-feeding.
3) Real-time PCR was used to analyze HNF4A expression at different timepoints after feeding. Primers were designed and validated
Obesity Awareness
Dr. Sharanya Rajan's document defines obesity and discusses its epidemiology. Key points include:
- Obesity is defined as a BMI ≥ 30 and is caused by an imbalance between energy intake and expenditure.
- Over 1.6 billion adults are overweight globally, with 400 million obese. Obesity is more common in women and increasingly affects poorer populations.
- Hypothalamic and genetic factors contribute to obesity development. Conditions like Prader-Willi syndrome, leptin/leptin receptor deficiencies, and POMC/MC4R mutations can cause monogenic obesity.
- Adipokines like leptin and resistin, as well as gut and pancreatic hormones, help regulate
The+Endocrine+System
The document summarizes key aspects of the endocrine system, including:
1) It coordinates slower responses to stimuli compared to the nervous system and regulates growth and homeostasis.
2) Hormones can be protein or steroid based, with different solubility and receptor interaction properties.
3) Feedback loops, second messengers, glands, and hormone interactions are described, highlighting control of processes like metabolism and development.
4) The hypothalamus, pituitary and thyroid glands interact in regulatory pathways, while other glands like the pancreas and gonads produce hormones controlling functions like blood sugar and sexual development.
The+ Endocrine+ System
The document summarizes key aspects of the endocrine system, including:
1) It coordinates slower responses to stimuli compared to the nervous system and regulates growth and homeostasis.
2) Hormones can be protein or steroid based, with different solubility and receptor interaction properties.
3) Feedback loops, second messengers, glands, and hormone interactions are described, highlighting control of processes like metabolism and development.
4) The hypothalamus, pituitary and thyroid glands interact in regulatory pathways, while other glands like the pancreas and gonads produce hormones controlling functions like blood sugar and sexual development.
Chapter+45
Both the nervous system and endocrine system regulate physiological processes, though they differ in their communication methods and response times. The endocrine system uses hormones like epinephrine, while the nervous system uses neurotransmitters. Key endocrine glands include the hypothalamus, pituitary gland, thyroid gland, adrenal glands, pancreas, ovaries/testes, and thymus gland. Hormone signaling occurs via models like the steroid model or protein model and involves signal transduction pathways.
Chapter+45
Both the nervous system and endocrine system regulate physiological processes, though they differ in their communication methods and response times. The endocrine system uses hormones like epinephrine, while the nervous system uses neurotransmitters. Key endocrine glands include the hypothalamus, pituitary gland, thyroid gland, adrenal glands, pancreas, ovaries/testes, and thymus gland. Hormone signaling occurs via models like the protein/steroid models and involves signal transduction pathways.
Thyroid hormones
The thyroid gland produces thyroid hormones T3 and T4 which regulate metabolism. T4 is the major hormone produced and is converted to the more active T3 in tissues. Their production involves iodine uptake and coupling of tyrosine residues in thyroglobulin. T3 and T4 act through nuclear receptors to regulate gene expression and increase metabolism. Disorders include hypothyroidism with low hormone levels and hyperthyroidism with excessive levels leading to increased metabolism. Tests are used to evaluate thyroid function and hormone levels.
obesity.pptx
This document defines obesity and discusses the regulation of appetite and factors involved in obesity. It provides epidemiological data on obesity rates globally and in India. Several genetic syndromes and monogenic causes of obesity are described, including deficiencies in leptin, the leptin receptor, POMC, and prohormone convertase 1, which all result in hyperphagia and severe early-onset obesity. Twin and adoption studies support a strong genetic component to obesity.
PROJECT PROPOSAL
This 3-sentence summary provides the key details about the document:
The document proposes a research project to identify inhibitors of the hormone-sensitive lipase (HSL) enzyme from food sources to control lipolysis and regulate fatty acid levels for managing obesity and preventing diabetes. The project would express and purify HSL, screen food extracts for inhibitors, test efficacy in cell and animal studies, and analyze effects on metabolic parameters and toxicity to identify potential HSL-inhibiting compounds for treating insulin resistance. The goal is to develop food-based therapies for obesity and diabetes by controlling HSL activity and fatty acid levels.
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Know Latest Hiranandani Hospital Powai News.pdf
As Mumbai's premier kidney transplant and donation center, L H Hiranandani Hospital Powai is not just a medical facility; it's a beacon of hope where cutting-edge science meets compassionate care, transforming lives and redefining the standards of kidney health in India.
一比一原版(UoA毕业证)昆士兰科技大学毕业证如何办理
UoA毕业证学历书【微信95270640】办文凭{昆士兰科技大学毕业证}Q微Q微信95270640UoA毕业证书成绩单/学历认证UoA Diploma未毕业、挂科怎么办？+QQ微信：Q微信95270640-大学Offer（申请大学）、成绩单（申请考研）、语言证书、在读证明、使馆公证、办真实留信网认证、真实大使馆认证、学历认证
办理国外昆士兰科技大学毕业证书 #成绩单改成绩 #教育部学历学位认证 #毕业证认证 #留服认证 #使馆认证（留学回国人员证明） #（证）等
真实教育部认证教育部存档中国教育部留学服务中心认证（即教育部留服认证）网站100%可查.
真实使馆认证（即留学人员回国证明）使馆存档可通过大使馆查询确认.
留信网认证国家专业人才认证中心颁发入库证书留信网永久存档可查.
昆士兰科技大学昆士兰科技大学毕业证文凭证书毕业证 #成绩单等全套材料从防伪到印刷从水印到钢印烫金跟学校原版100%相同.
国际留学归国服务中心：实体公司注册经营行业标杆精益求精！
国外毕业证学位证成绩单办理流程：
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- 1. THE OVERVIEW OF LEPTIN REPLACEMENT THERAPY
- 2. Leptin is a hormone that controls obesity and related health issues in human bodies. Scientists, for so many years, are engaged to discover how to use the leptin hormone to treat obesity.
- 3. Hundreds of renowned names are included in the list – for example, Tuncay Delibasi – the famous Turkish professor and a medical person who is doing his best to develop the advanced structure of leptin replacement therapy for obesity.
- 4. When leptin sends neurotransmitter signals to the brain in the hypothalamus sector, it tells the person to stop eating to maintain his/her desired BMI (Body Mass Index). Scientists have observed that laboratory mice have got polymorphism in their leptin gene. Such mutations in the gene prevent manufacturing the required leptin protein.
- 5. Due to the less leptin appearance, the lab mice have developed morbidity obesity. The other strain has the polymorphism or mutation in the gene encoding for LEPR (leptin receptor). In such cases, the brain or hypothalamus is not capable of receiving leptin signals. Therefore, signal disruption happens and it causes mutations of polymorphism in their leptin receptors and lab mice become obese.
- 6. A comparative study has shown the involvements of lean and obese individuals as per their leptin hormone levels. These types of comparative studies have developed the chances of leptin replacement to treat obesity. This is a medical treatment that controls leptin expression levels in obese people and helps them to control obesity. LEPTIN THERAPY
- 7. Leptin therapy is used to reverse endocrine and metabolic alterations that are associated with leptin deficiency. Less number of T- cells, defective T-cells and CD4 cause leptin deficiency. Leptin therapy can reverse these reductions. Tuncay Delibasi has discovered in his latest research that leptin replacement therapy is very useful for patients who are suffering from congenital leptin deficiency.
- 8. Leptin also is being used to treat energy loss such as anorexia nervosa. Scientists have found that immune function gets changed during leptin replacement.