The answer is E) 1,2, and 3. The solubility of a gas in solvents depends on their intermolecular interactions, which is affected by the nature of gas and the solvent as well as the temperature. So all three factors are relevant. Solution The answer is E) 1,2, and 3. The solubility of a gas in solvents depends on their intermolecular interactions, which is affected by the nature of gas and the solvent as well as the temperature. So all three factors are relevant..