This document summarizes Piramal e-Swasthya, an initiative that aims to provide affordable and reliable primary healthcare to rural India using innovative technology and service delivery models. It trains and employs local women as health entrepreneurs to set up telemedicine clinics in their homes. Villagers can visit these clinics to get diagnosed by the health worker, who then communicates the information to a call center via mobile phone. Experts at the call center provide treatment recommendations through a clinical decision support system. The model aims to scale up its services to reach 100,000 villages by 2013. It has the potential to improve healthcare access and quality in rural areas while empowering women.