The document discusses the SYNTAXES Study which compared percutaneous coronary intervention (PCI) to coronary artery bypass grafting (CABG) for all-cause death in patients with complex coronary artery disease over 10 years. The study found no significant difference in all-cause death between PCI and CABG in the overall cohort, with rates of 27.0% for PCI and 23.5% for CABG. For patients with left main or three-vessel disease, CABG resulted in lower rates of all-cause death compared to PCI.

1. Begoña Benito VillabrigaSYNTAXES StudySYNTAXES Study

2. Begoña Benito VillabrigaSYNTAXES StudySYNTAXES Study
BACKGROUND

3. Begoña Benito VillabrigaSYNTAXES StudySYNTAXES Study
BACKGROUND

4. Begoña Benito VillabrigaSYNTAXES StudySYNTAXES Study
BACKGROUND
All-cause death at 5 years

5. Begoña Benito VillabrigaSYNTAXES StudySYNTAXES Study
BACKGROUND

6. Begoña Benito VillabrigaSYNTAXES StudySYNTAXES Study
BACKGROUND
Overall
completeness of
follow-up: 94%

7. Begoña Benito VillabrigaSYNTAXES Study
Results: Patient characteristics

8. Begoña Benito VillabrigaSYNTAXES Study
Results: Primary end-point (10-year all-cause death)
Numbers
at risk
27.0% PCI
23.5% CABG
Overall cohort
HR 1.17, 95% CI (0.97-1.41), p = 0.092
Left main
Three-vessel

9. Begoña Benito VillabrigaSYNTAXES Study

10. Begoña Benito VillabrigaSYNTAXES Study
Conclusions
Complete study details in the Lancet Sept 2nd 2019