1) The document discusses how cognitive decline is common in aging adults due to reduced brain blood flow and increased theta brain wave activity. Preliminary studies have found that audio-visual entrainment may help rehabilitate cognitive function in seniors.
2) Psychological trauma from events like abuse or accidents can impair hippocampal function and increase risks of conditions like Alzheimer's through increased stress levels and reduced brain-derived neurotrophic factor. This can lead to irrational fears and early-onset dementia.
3) Falls are a major health issue for seniors, causing injuries, hospitalizations, and deaths. They account for 24% of emergency room visits and billions in annual costs. Seniors are much more likely than children to be seriously
Topic 6 - Aetiology of ADHD & Autism 2010Simon Bignell
Autism, Asperger's and ADHD
Topic 6 - Aetiology of ADHD & Autism.
The views expressed in this presentation are those of the individual Simon Bignell and not University of Derby.
Topic 6 - Aetiology of ADHD & Autism 2010Simon Bignell
Autism, Asperger's and ADHD
Topic 6 - Aetiology of ADHD & Autism.
The views expressed in this presentation are those of the individual Simon Bignell and not University of Derby.
Prof. Dr. Vladimir Trajkovski - Mental Health Issues in ASD-10.05.2019Vladimir Trajkovski
President of MSSA Prof. Dr. Vladimir Trajkovski presented this topic "Mental Health Issues in Autism Spectrum Disorders" at the mini simposyum in Voerandaal, Holland, organized by ReAttach Academy at May 10th 2019.
Audio-Visual Entrainment: Applying Audio-Visual Entrainment Technology for At...Mind Alive
Attention Deficit Disorder (ADD) and Attention Deficit Hyperactivity Disorder
(ADHD) are unique attentional disorders which primarily involve slowed frontal brain wave
activity and hypo-perfusion of cerebral blood flow in the frontal regions, particularly during
tasks such as reading. A variety of disorders, such as anxiety, depression and Oppositional
Defiant Disorder (ODD), are often co-morbid with ADD, thus creating a plethora of
complications in treatment procedures. Audio-Visual Entrainment (AVE) lends itself well for the
treatment of ADD/ADHD. AVE exerts a major wide spread influence over the cortex in terms of
dominant frequency. AVE has also been shown to produce dramatic increases in cerebral blood
flow. Several studies involving the use of AVE in the treatment of ADD/ADHD and its related
disorders have been completed. AVE as a treatment modality for ADD/ADHD has produced
wide-spread improvements including secondary improvements in IQ, behaviour, attention,
impulsiveness, hyperactivity, anxiety, depression, ODD and reading level. In particular, AVE
has proven itself to be an effective and affordable treatment of special-needs children within a
school setting.
The neurobiology of affective disorders and clinical implications of audio vi...Mind Alive
Affective disorders pertain to disorders of emotion, including depression and anxiety and mania. Affective disorders are generally the product of factors of geneticorigin and of environmental and lifestyle influences, more commonly known as the nature versus nurture paradigms.
Seniors: Getting Young Again by Boosting the Brain with Audio-Visual Entrainm...Mind Alive
Mind Alive Inc., an electronics manufacturing and design company incorporated in the province of Albertadesigns and manufactures a series of Audio-Visual Entrainment (AVE) devices. These products include the DAVID Delight, Delight Plus, Delight Pro, PAL, PAL36 and PAL36 with CES. These devices are being used worldwide to assist people from all walks of life to promote better health and increase relaxation.
A novel way of boosting grades and socialization while reducing stress in the...Mind Alive
The Digital Audio-Visual Integration Device (DAVID) enables the modification of brainwave frequencies to facilitate meditation, induce dream states and improve sleep patterns. The DAVID can also be used to accelerate brainwave frequencies to enhance mental performance, improve mood, and can even boost creativity.
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Prof. Dr. Vladimir Trajkovski - Mental Health Issues in ASD-10.05.2019Vladimir Trajkovski
President of MSSA Prof. Dr. Vladimir Trajkovski presented this topic "Mental Health Issues in Autism Spectrum Disorders" at the mini simposyum in Voerandaal, Holland, organized by ReAttach Academy at May 10th 2019.
Audio-Visual Entrainment: Applying Audio-Visual Entrainment Technology for At...Mind Alive
Attention Deficit Disorder (ADD) and Attention Deficit Hyperactivity Disorder
(ADHD) are unique attentional disorders which primarily involve slowed frontal brain wave
activity and hypo-perfusion of cerebral blood flow in the frontal regions, particularly during
tasks such as reading. A variety of disorders, such as anxiety, depression and Oppositional
Defiant Disorder (ODD), are often co-morbid with ADD, thus creating a plethora of
complications in treatment procedures. Audio-Visual Entrainment (AVE) lends itself well for the
treatment of ADD/ADHD. AVE exerts a major wide spread influence over the cortex in terms of
dominant frequency. AVE has also been shown to produce dramatic increases in cerebral blood
flow. Several studies involving the use of AVE in the treatment of ADD/ADHD and its related
disorders have been completed. AVE as a treatment modality for ADD/ADHD has produced
wide-spread improvements including secondary improvements in IQ, behaviour, attention,
impulsiveness, hyperactivity, anxiety, depression, ODD and reading level. In particular, AVE
has proven itself to be an effective and affordable treatment of special-needs children within a
school setting.
The neurobiology of affective disorders and clinical implications of audio vi...Mind Alive
Affective disorders pertain to disorders of emotion, including depression and anxiety and mania. Affective disorders are generally the product of factors of geneticorigin and of environmental and lifestyle influences, more commonly known as the nature versus nurture paradigms.
Seniors: Getting Young Again by Boosting the Brain with Audio-Visual Entrainm...Mind Alive
Mind Alive Inc., an electronics manufacturing and design company incorporated in the province of Albertadesigns and manufactures a series of Audio-Visual Entrainment (AVE) devices. These products include the DAVID Delight, Delight Plus, Delight Pro, PAL, PAL36 and PAL36 with CES. These devices are being used worldwide to assist people from all walks of life to promote better health and increase relaxation.
A novel way of boosting grades and socialization while reducing stress in the...Mind Alive
The Digital Audio-Visual Integration Device (DAVID) enables the modification of brainwave frequencies to facilitate meditation, induce dream states and improve sleep patterns. The DAVID can also be used to accelerate brainwave frequencies to enhance mental performance, improve mood, and can even boost creativity.
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...
Mental Health Treatment - AVE
1. Mind Alive Inc., 6716 – 75 Street, Edmonton, Alberta, Canada T6E 6T9 www.mindalive.com
Copyright 2006. Reproduction of this material for personal use only.
Reproduction for marketing purposes is prohibited without permission from Mind Alive Inc.
Page 1
Seniors: Getting Young Again by Boosting the Brain
with Audio-Visual Entrainment
David Sieveri
, Edmonton, Alberta, Canada (2005) Revised: (2015)
Abstract: As the majority of the North American population continues to age, cognitive decline in older
adults is becoming an ever-growing concern. With the increase in age comes a decrease in cerebral
blood flow, slowing of the brain’s alpha rhythm and increased theta activity. These changes correlate
with reduced cognition, spanning memory, problem solving ability, difficulty with language and speech,
and locomotion. Chronic stress impairs hippocampal function leading to a host of disorders including
Alzheimer’s disease. The left hemisphere of the brain has a tendency to loose functionality before the
right side, which may enhance spatial creativity and when coupled with fears and feelings of helplessness,
may also bring forth depression. Preliminary studies of Audio-visual entrainment (AVE) have shown this
technique to be promising in the treatment of age-related issues common with our senior citizens. AVE is
proving to rehabilitate cognitive function in seniors and the best application of AVE may be that as a
prophylactic against cognitive decline.
Introduction
Cognitive decline and dementia in aging adults is an ever-growing problem, not only because the
numbers of older adults are expanding, but longer life increases the likelihood of loss of memory
and decline in cognitive performance (dementia). The Diagnostic and Statistical Manual of
Mental Disorders (DSM IV) describes dementia in this basic statement: The essential feature of a
dementia is the development of multiple cognitive deficits that include memory impairment and
one or more of the following cognitive disturbances: aphasia, (impaired ability to use and
comprehend words); apraxia (brain originated difficulty moving parts of the mouth, tongue or
lips with impaired speech); agnosia (difficulty recognizing shapes or copying drawings) or a
disturbance in executive functioning (logical thinking). The cognitive deficits must be severe
enough to cause impairment in occupational or social functioning and must represent a decline
from a previously higher level of functioning. (American Psychiatric Association, 1994, p. 134).
Dementia in both the more common ischemic vascular dementia (IVD) and dementia of the
Alzheimer’s type (DAT) increase linearly with increasing age (Mohs, et al., 1987; Rocca, et al.,
1991) to the point where these dementias have become epidemic within our aging population
(Fratiglioni, et al., 1991; Bachman, et al., 1992). Mortel and his colleagues (1994) states, “The
pathogenesis of DAT appears to be largely determined and characterized by beta amyloid
deposits, neurofibrilliary tangles, and neuritic plaques that impair cortical and sub-cortical
synaptic function.” Their study also found that in the IVD population, hypertension and smoking
are roughly 1.5 times that of normal, heart disease is double and diabetes is triple that of normal.
In the DAT population, hypertension is roughly 2/3 that of normal and heart disease is ½ that of
normal. DAT has also been characterized as a “hippocampal dementia” and autopsies have
revealed a high correlation of excessive theta brain wave activity with neuronal loss in the
hippocampi (Rae-Grant et al, 1987).
2. Mind Alive Inc., 6716 – 75 Street, Edmonton, Alberta, Canada T6E 6T9 www.mindalive.com
Copyright 2006. Reproduction of this material for personal use only.
Reproduction for marketing purposes is prohibited without permission from Mind Alive Inc.
Page 2
Here Cometh the Rain Man
Some of those with autism have brilliant skills known as savant abilities. The skills they possess
are the aftermath of left brain damage or dysfunction from fetal testosterone or other damage and
are therefore typically confined to right brain functioning, which includes music, math, art and
other spatial abilities. Some can play complete concertos after hearing them only once. Others
have memorized every name in the phone book or every highway in the USA or draw pictures of
amazing detail after just a brief exposure to a scene. Some have brilliant knowledge of sports
trivia or license plate numbers. Although these skills are intrinsically tied to a remarkable,
specific memory, savants with them lack an understanding of any meaning or reasoning as to
what they are doing.
And there may be a little “Rain Man” in all of us because, like autistic savants, as some seniors
develop certain types of dementia, they become brilliant with artistic and musical abilities
(Treffert & Wallace, 2002; Miller, et al., 1998). Neurons in the left temporal and frontal lobes
(frontotemporal dementia) appear to be more delicate than those in the right and often take the
“hit” sooner in life, allowing the right hemisphere to take control, and like autistic savants, leave
the inflicted with a loss of reasoning ability but heightened artistic and musical ability (Treffert
& Wallace, 2002). These seniors paint magnificent drawings or play concertos even though they
have never had these abilities before. Unfortunately, as dementia spreads into the right brain,
these skills eventually disappear, leaving the person in a withered condition.
Haunted By the Past
The American Psychiatric Association defines psychological trauma as a threat to life, to
yourself or someone close to you accompanied by intense fear, horror or helplessness.
Psychological trauma affects about half of all Americans sometime in their lives. Every year, in
the USA, more than 1 million children are confirmed as victims of child abuse (Teicher, M.,
2002). Close to 50 million American adults have been abused in childhood alone, not to mention
adult traumas, leaving about 30 million Americans with posttraumatic stress disorder (PTSD),
making it one of the most common illnesses in the USA (Bremner, 2002). A full 8% of
Americans have a history of PTSD related to a wide variety of incidents including child abuse,
assault, rape, car accidents, natural disasters, etc. (Kessler, et al, 1995). There are roughly tenfold
more civilian Americans suffering from trauma and PTSD than those with combat trauma in
military personnel.
While acute (mild) stress seems to enhance mental function, chronic (severe) stress impairs
hippocampal function, which in turn, may lead to multiple sclerosis, anxiety, depression,
posttraumatic stress disorder, schizophrenia and Alzheimer's disease (Esch, et al., 2002). Both
Vietnam war-vets and women with abuse-related PTSD have reduced blood flow in the
hippocampus and medial prefrontal cortex (Bremner, et al, 1999). People with PTSD do not have
normal activation of the prefrontal medial cortex and are not able to extinguish their own fear
responses while watching a movie involving violence (Bremner, et al., 1997), whereas people
without PTSD are able to rationalize that they are only watching a movie and do not show a
3. Mind Alive Inc., 6716 – 75 Street, Edmonton, Alberta, Canada T6E 6T9 www.mindalive.com
Copyright 2006. Reproduction of this material for personal use only.
Reproduction for marketing purposes is prohibited without permission from Mind Alive Inc.
Page 3
trauma response to the movie. What this means is that those with PTSD live in an irrational and
constant state of fear.
Fear also inflicts continued damage to the frontal and temporal regions, known as frontotemporal
dementia (Bremner, 2002). Frontotemporal damage impairs the ability to control fear and the
ability to reason and understand the significance of events in their lives (Bremner, 2002), leaving
the inflicted in a generalized state of anxiety, fear and confusion. Anxiety and fear increases
cortisol in the brain. Cortisol counteracts a brain-nourishing hormone called brain-derived
neurotrophic factor or BDNF (Bremner, 2002). Loss of BDNF leads to neuronal cell death
within the hippocampus, which impairs memory. As mentioned above, hippocampal loss plays a
major role in the development of DAT in which the ability to form memories is impaired. In fact,
those inflicted with PTSD often cannot remember what they had for breakfast a few hours before
and have extreme difficulty learning new things. Unfortunately, PTSD inflicted dementia can
affect persons as young as teenagers and up (Bremner, 2002). Seniors who live in fear suffer
early onset dementia.
In relation to fear, a 1996 study by Levy revealed that when seniors were given subconscious
cues which activated positive stereotypes of aging, their memory and self-reliance in
remembering improved and when they were given negative subconscious cues, their memory
and self-reliance in remembering worsened. What most influenced their response however, was
the degree of importance that stereotyping was to their self-image – a negative stereotype
activated fears within them and impaired their memory and self-reliance in remembering. Those
who weren’t concerned about self-image didn’t respond either way.
I’m Falling for You (or anything near the floor) Baby
Falls involving both seniors and children account for approximately 24% of the 147 million
emergency room visits logged every year (Burt & Fingerhut, 1998) and with 7 million annual
falls involving seniors over the age of 65 years (Jacobson, 2001; Zaida & Alexander, 2001) with
costs soaring as high as $12.4 billion annually within the USA (National Safety Council, 1996).
Compared with children, however, seniors are 10 times more likely to be hospitalized and eight
times more likely to die as a direct result of their fall (Runge, 1993). In fact, falls are the leading
cause of injuries and injury-related deaths among persons aged 65 and older (Fife & Barancik,
1985; Hoyert, et. al., 1999). Falls are the cause of 95% of hip fractures in senior women (Stevens
& Olsen, 1999). Hip fractures in turn are associated with decreased mobility, onset of depression
(Scaf-Klomp, et al., 2003), diminished quality of life, and premature death (Zuckerman, 1996).
Older age, depression, and gait or balance impairments are primary factors for inability to get up
after a fall (Colon-Emeric, 2002). In summary, falls involving seniors come at great emotional
and financial cost in those communities where an abundance of seniors reside.
4. Mind Alive Inc., 6716 – 75 Street, Edmonton, Alberta, Canada T6E 6T9 www.mindalive.com
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Brain Waves and Dementia
The brain generates four basic brain waves: delta, theta, alpha and beta. Beta brain waves are in
the frequency range of 13 to 35 Hz. For the purpose of this article we will consider beta activity
in the frequency range of approximately 13 to 20 Hz. This beta activity is associated with a
focused, analytic, thinking state (Demos, 2005). Beta activity is more prevalent in the frontal
regions where higher levels of cognitive thought and reasoning take place.
Theta brain waves are in the 4 to 7 Hz range. Theta activity is associated with creativity and
daydreaming, but also with distractibility, inattention and emotional disorders (Demos, 2005).
Theta is the primary abnormal brain wave of children with ADHD. Normal theta/beta ratios for
children are in the range of 2.5 to 1 and 2 to 1 in adults. Heightened theta/beta ratios are
coincident with slow brain wave disorders and associated with foggy thinking, slow reaction
times, difficulty with calculations, poor judgment and impulse control (Demos, 2005).
Delta brain waves are primarily related to sleep and therefore make up 40% of all brain wave
activity in babies and only 5% of activity in adults. High amplitude, rhythmic delta activity is
associated with traumatic brain injury (Demos, 2005).
Many brain wave studies have confirmed a natural slowing of alpha activity with age, which is
associated with a shorter life (Nakano, 1992). It has also been shown that an increase in overall
theta activity is the best and earliest indicator of cognitive decline (Prichep, et al., 1994).
The Geriatric Deterioration Scale (GDS) is a seven-stage subjective assessment of DAT. Stage 1
represents the best cognitive function while higher stages represent increases in dementia up to
Stage 7, which reflects severe DAT. Prichep found a direct and linear correlation between
progressive increases in theta and increases in severity of cognitive decline as measured on the
GDS from stages 2 through 5. The severest stages of cognitive decline (stages 6 and 7) correlated
highly with additional increases in delta, the slowest brain wave rhythm (normally associated
with sleep or severe brain damage. The regions in the brain with the highest increases in theta
carved a temporoparietal arc across the head.
Cerebral Blood Flow
Cerebral blood flow (CBF) has been shown to decline fairly linearly with age (Hagstadius &
Risberg, 1989) and with men having less CBF than women (Gur, et al, 1987) as shown in Figure
1. Both IVD and DAT groups have roughly 4% less cerebral blood flow (62 ml/100g of brain
weight/minute vs 67 ml/100g of brain weight/minute) than controls (Mortel, et al., 1994). Hirsch,
et al (1997) in a study of 45 seniors with DAT, found that the majority of blood flow deficits
were in both left and right temporoparietal regions. When the left side was affected, language
impairments developed and when the right side was affected, there were impairments in praxis
(the ability to be proficient in doing normal, habitual activities).
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Figure 1. CBF Declining with Age
Entrainment and Dementia
Visual entrainment (VE) is affected by dementia. Visual entrainment normally has its greatest
impact at the natural alpha frequency, which is typically about 10 Hz (Siever, 2003). Dementia
causes a downward skew in the peak brain wave frequency, which in turn also causes a slowed
frequency response to VE (Politoff, et al., 1992). However, despite this downward shift, VE
nonetheless, affects a wide range of brain wave activity (Politoff, et al., 1992), making it a viable
method for reducing aberrant dementia related brain wave activity.
VE also produces increases in cerebral blood flow, which would seem to be beneficial since
dementia involves a reduction in cerebral blood flow. Figure 2 shows the impact of VE on
cerebral blood flow in response to various frequencies (Fox & Raichle, 1985).
Figure 2
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Studies Utilizing Audio-Visual Entrainment (AVE) for
Improving Cognitive Ability and Balance
One of the first studies utilizing AVE for improving cognition in a senior was by Tom Budzynski
(1998), where he used both neurofeedback and AVE to improve mental function in a 75-year-old
man. In a further study using a DAVID Paradise XL and a 10-station multiple system, Budzynski
& Tang (2001) treated 31 seniors from two seniors’ homes in Seattle. They used audio-visual
stimulation (AVS) “sessions” in the form of random frequency stimulation from 9 to 22 Hz over
an average of 33 treatments to rejuvenate brain function. Because 10 people were treated at a
time, treatment was very cost effective as compared with one-on-one therapy such as cognitive
rehabilitation or neurofeedback. A computer based continuous performance test (CPT), the
Microcogii
, was used to assess mental function (Elwood, 2001).
The Microcog measures attention, reasoning ability, memory, spatial ability, reaction times,
processing speed and accuracy, cognition and proficiency. Approximately 60 to 70% of all
subjects (Figure 3) showed improvements in these measures. Figure 4 shows the average group
improvements in different measures within the Microcog.
Figure 3. Microcog Results Following AVE - % of Seniors with Improvement.
Figure 4. Microcog Results Following AVE – Amount of Improvement.
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Within the group was one woman with rapidly progressing dementia of the Alzheimer’s type.
Because of the severity of her dementia, a full quantitative electroencephalogram (QEEG) and
Low Resolution Brain Electromagnetic Tomography (LORETA) assessment was performed. The
LORETA is a technique which provides a three dimensional view into the subcortical structures
of the brain (Pascual-Marqui, 2002). According to the LORETA, the AVS appeared to produce
improvement in various brain regions that are involved in the progression of DAT. The results
appeared during the first AVS stimulation period and lasted through the continuation of the 33-
session treatment period. Specifically, the LORETA showed decreases in abnormal delta in the
left temporal lobe and in the superior temporal gyrus and continued beyond the 30-session
treatment. In other words, AVS halted the progression of her DAT and reversed its effects to
some degree. This is the first evidence that AVS and perhaps AVE could be used as a
prophylactic against age-related dementia.
Seniors and Locomotion
Interventions to reduce the risk of falling by reducing depressive symptoms have been only
partly successful among the elderly living in the community. Successful studies have used
multifaceted approaches including exercise programs, home modifications, falls-prevention
education, improving vision and hearing, alcohol abuse awareness, and wearing safer footwear
(Rubenstein et al., 1990; Steinberg et al., 2000; Tinetti et al., 1994). However, a perceived
problem with interpreting the findings of multifactorial interventions is that determining which
component of the intervention program was more effective in reducing depressive symptoms is
not always possible (Cumming, 2002). This is a particular concern for public health
professionals who want to plan cost-effectiveness fall-prevention strategies for whole
populations of elderly persons.
The focus of this present study is to develop a single intervention. Particularly one that will
decrease depressive symptoms and reduce falls in the elderly living in the community. This
intervention, which involves entraining brain waves, is commonly known as audio-visual
entrainment (AVE). AVE differs from AVS in that AVE involves stimulation for several minutes
of a non-changing or only slightly changing frequency whereas AVS employs fairly random
frequencies. The frequency of stimulation when using AVE is clearly visible in the EEG of the
brain of the person who is receiving the stimulation whereas AVS is not.
Evidence in the literature demonstrates a link between AVE and the reduction of depression
(Kumano, et al, 1996; Berg & Siever, 2000). However, the precise relationship between AVE
and falling remains unclear. It is plausible that a cognitively intact older person who falls or
almost falls could reduce his/her chances of future falls by improving his/her precipitating
depressive symptoms. The most common origin of depression is related to hypoactivation of the
left frontal lobe function (Rosenfeld, 1997; Davidson, et al., 1999), which is observed as
heightened alpha activity. This heightened left alpha creates an alpha asymmetry between the left
and right frontal lobes, often leaving the right side hyperactivated with the outcome being
anxiety (Davidson, et al., 1999). It is plausible that AVE administered in such a way that inhibits
left frontal lobe alpha will improve cognition simultaneously while reducing depression and
anxiety. In this study, that is exactly what was done (anxiety, however, wasn’t measured).
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The study involving 80 randomly assigned seniors by Berg & Siever (2004), shown in Figures 12
and 13, utilized a stimulus of 17 to19 Hz in the right visual fields and right headphone (left brain
stimulation) and provided a stimulus at 10 Hz in the left visual fields and left headphone (right
brain stimulation) during a 30-minute preprogrammed session. This approach normalized the
asymmetry in brain “alpha” activity that is typical of depression (Rosenfeld, 1997). As a result,
depression recorded on the Geriatric Depression Scale (GDS) was reduced significantly (Figure
5).
Figure 5. Geriatric Depression Scale
Balance and gait were measured using the Tinetti Assessment Tool (Tinetti, 1986). Figure 6
shows the improvement in balance as seen on the Balance Mean Scores (BMS). As depression
lifted, balance improved.
Figure 6. Balance Mean Scores
In the first month balance improved considerably (P=0.0055), which is seen as a negative
correlation (Figure 7). Gait, however, didn’t improve within the first four weeks (p=0.112). Gait,
however, did improve once the fear of falling was reduced and confidence was restored. About
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four weeks on average was required before the participants trusted themselves enough to begin
walking with a straighter gait. Their gait continued to improve throughout the eight weeks
(p=0.0001).
Figure 7. Correlation of Balance & Gait in Relation to Initial Depression Scores
Memory and mental sharpness are also of major importance to seniors. When memory begins to
slide, the inflicted often forgets conversations, people, grandchildren, where they parked their car
or when they last took their pills. They may become very anxious as the fear of becoming a
“lost” person mounts. And anxiety further impairs memory, so it becomes a double-edged sword.
Mental sharpness, memory and reaction times are correlated with brain wave activity. With
slower brain waves comes the slower cognition and poorer memory. Fortunately, AVE at beta
and sensory motor rhythm (SMR) frequencies can reverse these effects of aging. A study by
Chris Palmquist (2014) found significant improvements in immediate and short-term memory as
well as increased alpha brain wave frequency, as shown in Figure 8. The CANS-MCI (computer-
assisted Neurophysiological Screen for Mild Cognitive Impairment) (Wild, Howieson, Webbe,
Seelye and Kaye, 2008) shows that seniors in the control group had even poorer immediate and
short-term memory on retest than at the start and their peak-alpha frequency was basically
unchanged. What this means is that the placebo condition had no beneficial effect on their
memory or brain wave production.
Regarding the treatment group, the graph represents an almost 2-fold improvement in memory as
compared with the controls, and that is very significant to a senior’s life. Normal peak-alpha
frequency is close to 10 Hz, so a baseline of 9.5 shows that brain waves are already slowing
some with age. By nudging their alpha frequency back up to almost 9.9 Hz, their brain waves
have become more similar to that made by a 30-40 year old.
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Figure 8. Improvements in Memory and Alpha Frequency Following Berta/SMR AVE
Stimulation.
Conclusion
AVE plays a vital role on maintain and even improving attention and cognitive function in
seniors. AVE increases energy, reduces depression, and reduces the risk of falling by improving
balance and gait. AVE roughly doubles memory and speeds up peak alpha frequency, a marker
of mental ability.
Given that memory, overall mental sharpness and cognition (such as problem solving ability) are
all improved over roughly 30 sessions and may be done in the comforts of one’s own home, how
much more improvement could have occurred over lets-say 60 sessions – or a year? Could that
senior go back to school and get that degree he or she always wished they had? Could that senior
go on a trip around the world and keep a handle on air-flights, hotels, various bookings and the
joys of visiting far exotic places? Could they share many wonderful years with their children and
grandchildren. From a mental health perspective, the answer is simply YES, it is very possible!
After the initial purchase of a device for under $500, the use of an AVE is free. There is NO drug
that can replicate the benefits of AVE for an aging population. This is one technology that every
senior should have by his/her bedside. It’s easy to use, relaxing and most importantly – free!
i
Address all correspondence to David Siever at Mind Alive Inc. Toll Free: 1-800-661-MIND (6463),
Ph: 780-465-6463 Address: 6716 – 75 Street, Edmonton, Alberta, Canada, T6E 6T9.
Web: www.mindalive.com Email: info@mindalive.com
ii
Microcog. Harcourt Assessment Inc. San Antonio, TX. USA. Ph: 800-211-8378.
Website: www.harcourtassessment.com.
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