24. Poroma shows intraepidermal nests of small monotonous polygonal c
ells with low mitotic activity. The tumor cells generally demonstrate dir
ect downward growth into the dermis as interconnected basaloid prolif
erations. The intraepidermal nests of basaloid cells are smaller than th
e adjacent keratinocytes and show intercellular bridges.
25.
26. Poroma are three types:
A. Intraepidermal poroma (Hidroacanthoma simplex)
B. Intradermal poroma (Dermal duct tumor)
C. Poroma (Compound poroma), the most common type
Эмнэлзүй:
Шарх үүсэх нь эмнэлзүйн гол шинж. Тухайн шарх голчлон йлга уланд гарах бөгөөд арьсны бусад
бүтцээс ялгагдахуйц, өргөгдсөн байх ба экзофит ургалттай, ягаан улаан өнгөтэй, диаметр нь 1-2
см хүрч болно. Дермоскопиор оношлоход зарим тохиолдолд нөсөөжил үүссэн байх ба нөсөөжсөн
суурь эсийн хорт хавдартай ижил харагддаг.
Жирэмсэн үед харьцангуй хурдан өсөх ба мөөгөнцарт эмгэгийн электрон эмчилгээний дараа, ту
яа эмчилгээний дараа, хэсэг газрын түлэгдэл-н дараа үүсэх өндөр магадлалтай.
Prognosis ---Тухайн шарх хоргүй бөгөөд нийт тохиолдлын 18 хувь нь хортой хавдар луу шилжих
магадлалтай
Эмчилгээ: Мэс заслын аргаар авах эмчилгээ хийгдэнэ.
28. Эмнэлзүй: Олон тооны хавтгай оройтой, арьснаас бага зэрэг дээш өргөгдсөн, 1-3мм хэмжэ
этэй эрүүл арьстай адил өнгөтэй гүвдрүүнүүд үүсдэг.
Өвчтөнд ямар нэгэн зовиур байхгүй бөгөөд ихэвчлэн зовхины эргэн тойронд байрлах ба их
биеэр тархаж болно.
Эмчилгээ:
Хорт хавдарт шиождэггүй бөгөөд СО2 эмчилгээ, лазер буюу хөлдөөх /крио/ эмчилгээ үр
дүнтэй.
patients with Down syndrome
during radiotherapy for breast cancer -----Магадлал өндөр
29. Eruptive syringomas are more common in African Americans and Asians.
Four variants of syringoma : (1) localized form, (2) associated with Down
syndrome, (3) generalized multiple and eruptive syringomas, and (4) famil
ial.
Epidermis is normal. Upper
dermis shows numerous
small epithelial ducts embed
-ded in sclerotic stroma. The
walls of the ducts are lined
by two layers of cuboidal or
flat epithelial cells. Ductal
lumen contains eosinophilic
, amorphous debris. Some
ducts have elongated tails of
epithelial cells that produce
a comma-shaped or tadpole
appearance.
31. Cylindroma
Lobules of epithelial cells arranged in a jigsaw or mosaic pattern. Promin
ent red basement membrane-like structure encircles the tumor lobules.
Each lobule shows a peripheral lining by dark basaloid cells and an inner
larger and paler zone of cells.
32. Cylindroma
Clinical: Sex: mostly female. Location: mostly scalp.
Slow-growing, sometimes painful solitary pink or re
d dermal nodule averaging 1 cm in size.
Familial cases are associated with multiple tumors.
Such cases may also be associated with facial trichoepi
theliomas, and eccrine spiradenomas, called autoso
mal dominant Brooke-Spiegler syndrome (familial c
ylindromatosis or turban tumor syndrome).
Pathologic features:
-Non-encapsulated dermal tumor not connected
to the overlying epidermis.
-Composed of numerous lobules of epithelial cells
arranged in a jigsaw or mosaic pattern.
-Prominent red basement membrane-like structure
encircles the tumor lobules.
.
33. Spiradenoma
Well-circumscribed or encapsulated dermal nodule composed of small dark
basaloid and large pale epithelial cells within a vascular stroma. Low-power
view resembles a lymph node. Stroma contains appreciable number of lymp
hocytes. Cuboidal epithelial cells form compacted cords with occasional duc
tal lumen formation with eosinophilic cuticle.Hyalinized matrix around the
epithelial cords may resemble that of cylindroma.
34. Spiradenoma
• Clinical:
• Painful, solitary dermal tumor in the skin of upper half of the
body.
• Multiple tumors may be part of Brooke-Spiegler syndrome.
• Pathology:
• Well-circumscribed or encapsulated dermal nodule composed
of small dark basaloid and large pale epithelial cells within a
vascular stroma.
• Low-power view resembles a lymph node.
• Stroma contains appreciable number of lymphocytes.
• Cuboidal epithelial cells form compacted cords with occasional
ductal lumen formation with eosinophilic cuticle.
• Hyalinized matrix around the epithelial cords may resemble th
at of cylindroma.
35. Hidradenoma
Well circumscribed, un-encapsulated solid and cystic lobular dermal tum
or, 50% connected to the epidermis. Biphasic cellular pattern: areas of r
ound, fusiform, polygonal squamoid cells with eosinophilic cytoplasm an
d cells with clear cytoplasm. Duct-like structures, cystic change, focal ap
ocrine change, squamous eddies, goblet cells etc may be present.
36. Hidradenoma
Location: mostly head and neck, limbs, or any site.
• Middle age and elderly, F>M.
• Solitary, slow-growing solid or cystic dermal nodule, 1-2 cm.
• Well circumscribed, un-encapsulated solid and cystic lobular dermal
tumor, 50% connected to the epidermis.
• Biphasic cellular pattern: areas of round, fusiform, polygonal squam
oid cells with eosinophilic cytoplasm and cells with clear cytoplasm.
• Stroma is fibrovascular, collagenous or hyalinized.
• Tumor ‘budding’ from the periphery to the surrounding dermis sho
uld be considered as a low-grade malignant tumor.
• Diffuse nuclear anaplasia, necrosis and tumor giant cells may
suggest malignancy.
38. Mostly in the eyelids. Dermal cyst lined by cuboidal ductal epithelium
of sweat gland containing fluid, not keratin. Eccrine or apocrine type
epithelial cells may suggest the origin.
Hidrocystoma
39.
40. Syringocystadenoma papilliferum
Epidermis shows acanthosis and papillomatosis. Cystic invaginations
with papillary projections extend downward from the epidermis. The
papillary projections are lined by two layers of cuboidal and columnar
epithelial cells. The stroma is infiltrated by a numerous plasma cells.
41. Syringocystadenoma papilliferum
• Syringocystadenoma papilliferum (SP) is a benign adnexal tum
or, most commonly located on the scalp or face, which freque
ntly arises from a nevus sebaceus (NS).
. Luminal cells may show decapitation secretion.
The stroma is infiltrated by a numerous plasma cells.
Malformed sebaceous glands and hair structures may be present
.
49. Mixed tumor with skin:
Chondroid syringoma
• Middle aged males
• Rare children
• No sex predilion
50. Chondroid syringoma
• Chondroid syringoma is most commonly
found on the head, neck, and scalp.
• Less frequently, it may also be seen on the
trunk, axilla, inguinal area, and genitalia; rar
ely, it has been reported on the eyelid and
external auditory canal.
51. • This tumour is usually found on the head and neck, followed by
the trunk and the extremities, as a solitary nodule. The lesions
are frequently large and nodular, sometimes with a diameter of
5–10 cm
52. Ном зүй:
• Б.Хандсүрэн Арьсны өвчин 2010 он р291
• Christopher Griffiths, Jonathan Barker, Tanya Bleiker, Robert Chalm
ers, Daniel Creamer-Rook’s Textbook of Dermatology. 1-4-Wiley-Bla
ckwell (2016) р3815-3830
• Д.Цолмон, Ц.Тунгалаг Гистологийн сурах бичиг 2 боть, 2011 он
р184-186
• Kenneth S.Saladin Anatomy&Physiology 7th edition /2015/ p191-192
• Plasticsurgerykey.com