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抗老化生技實驗室 研發成果介紹
[object Object]
[object Object]
[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Beckman Cell Lab Quanta SC 流式細胞儀
Day 0 Day 10 ,[object Object],[object Object],[object Object]
幹細胞  (Stem cell) ,[object Object],[object Object],[object Object],[object Object]
骨髓內的多效性幹細胞 造血幹細胞  (hematopoietic stem cells, HSC)  間葉幹細胞  (mesenchymal stem cell, MSC) 主要分化為免疫系統細胞 ( 如 T cell, B cell) , 血球細胞 ( 紅血球、白血球、血小板 ) 主要分化為間葉組織 ( 如造骨細胞、軟骨母細胞、脂肪細胞 ) 應用: 細胞療法 應用 : 重建血液與免疫系統
幹細胞激活因子之微陣晶片測試 PDGF-BB :血小板衍生生長因子,刺激     纖維母細胞再生與膠原蛋白合成 SCF  :幹細胞生長因子,刺激幹細胞遷徙與增殖 IGF-1  :第一型胰導素生長因子,人類組織細胞之重要生長激素 TGF-β3  :轉型生長因子 -β3 ,促進傷口癒合 , 減少疤痕形成  EGF  :上皮生長因子 ,促進上皮再生 VEGF  :血管上皮生長因子,促進血管上皮細胞再生 bFGF  :纖維母細胞生長因子 IFN-γ  :干擾素 , 抗病毒、抗腫瘤,具有免疫調節功能 LEPTIN  :脂肪抑制素,調節體重、代謝、食慾 RANTES  :趨化因子,活化免疫細胞
2.  強化修護與細胞新生
3.  微奈米化微脂體 (liposome) 包裹 模擬細胞膜組成的微脂體特殊配方 , 提供極佳滲透性 標榜:微奈米化微脂體 , 塗抹 15 分鐘後到達真皮層
Hair Growth Cycle
Testosterone DHT 5α-reductase  Androgen receptor   (dihydrotestosterone) androgenetic alopecia 雄性禿患者位於 前額 、 頭頂 及 後枕上部 的頭髮毛囊對於 DHT 特別敏感,毛囊在經過 DHT 的刺激之下會逐漸萎縮,並 激發 皮脂增生 阻塞毛囊, 因此頭髮越長越細,終至毛囊死亡不再長出頭髮。 DHT
Propecia Rogaine (minoxidil)  (finasteride) C 23 H 36 N 2 O 2 MW 372.55
醫學證實 ,[object Object],[object Object]
 
Day 0 Day 10 Hair follicle cultured in vitro
Parkinson’s disease pathology ,[object Object]
C57BL-6J  老化小鼠 年輕對照組 8 週 齡 餵食食鹽水 老化小鼠組 餵食微脂體包裹生長因子 (X + Y) 老化小鼠組 60 週 齡 60 週 齡 ,[object Object],[object Object]

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