30-40% of patients with unexplained weight gain may have non-celiac gluten sensitivity or sub-clinical gluten enteropathy, according to Dr. David S. Klein, an expert in pain medicine. Dr. Klein has over 27 years of experience and is the author of over 50 publications, noting that gluten-related illnesses often present atypically, without classical gastrointestinal symptoms. He is the Medical Director of the Pain Center of Orlando and specializes in diagnosing gluten sensitivity in patients with unexplained health issues.