Four key events led to the Spanish-American War: 1. The Cuban revolt for independence and Spain's brutal suppression of it under General Weyler, known as "The Butcher". 2. Yellow journalism in American newspapers inflamed public opinion by publishing exaggerated and false stories about Spanish atrocities in Cuba. 3. The publication of an insulting letter written by the Spanish ambassador to the US about President McKinley. 4. The sinking of the USS Maine in Havana harbor, which inflamed public opinion and calls of "Remember the Maine!" despite uncertainty over the exact cause of the explosion.