This document presents an overview of sustainable enterprise and successful business examples. It discusses the three pillars of sustainability—social, environmental, and economic—and how businesses can create social impact and innovation for competitive advantage. An example of a sustainable business model called S.A.M.B.A. is described. The document also covers skills needed for sustainable enterprises, such as passion, multidisciplinary thinking, and creativity. A brief history of trade and business is provided, mentioning early civilizations in Mesopotamia, along sea and land routes.