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Sle and stroke for lupeans
- 1. Understanding Stroke andLupus by Elaine T. Veῆegas, MD March 2, 2013
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- 16. What organs areaffected by Lupus?
- 17. What organs areaffected by Lupus? LUNGS KIDNEYS HEART
- 18. What organs areaffected by Lupus? DIGESTIVEBLOOD NERVOUS S.
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- 20. What is Stroke? ISCHEMICSTROKE (INFARCT) HEMORRHAGIC STROKE
- 21. How does lupuscause STROKE?
- 22. Causes of STROKEin lupus ABNORMAL ANTIBODIES: Antiphospholipid antibodies (APA) Anticardiolipin antibodies Lupus anticoagulant ATTACK the blood vessel initiates the formation of BLOOD CLOTS EMBOLIC STROKE “Sticky Blood Syndrome”
- 23. Antiphospholipid Antibody Syndrome (APAS):“sticky blood syndrome” Twenty to 35% of women with SLE develop APAS APAS occurs for the most part in young women of fertile age CRITERIA: Vascular thrombosis pregnancy morbidity
- 24. Antiphospholipid Antibody Syndrome (APAS):“sticky blood syndrome” CRITERIA: Vascular thrombosis In any tissue or organ pregnancy morbidity 1 or more unexplained fetal death at 10 wks or beyond OR 1 or more premature birth at or before 34thwk AOG OR – 3 or more consecutive spontaneous abortions Anticardiolipin antibodies Lupus anticoagulant
- 25. Causes of STROKEin lupus VASCULITIS: Antibodies ATTACK the blood vessel INFLAMMATION DECREASES blood flow
- 26. Causes of STROKEin lupus ATHEROSCLEROSIS: ARTERIES are NARROWED by plaque DECREASES blood flow
- 27. TRANSIENT ISCHEMIC ATTACK A mini-stroke Symptoms last a few minutes or hours Never ignore a TIA ! It is often a sign that a more damaging stroke is on the way
- 28. WARNING SIGNS OFSTROKE weakness on one side of the body loss of speech or trouble understanding speech loss of vision, particularly on one eye or double vision dizziness and loss of balance numbness/tingling in the face/arm/leg slurring of speech severe and unusual headache SUDDEN….
- 29. What to doin case of Stroke ? the signs of stroke Do not wait. Go to the nearest ER or hospital with facilities for stroke care
- 31. Seek help rightaway ! 0 - 3 hours treatments most effective Clot lysis with IV rtPAClot
- 32. When we controllupus, we help control stroke Remember…
- 33. REDUCING OUR CHANCEof stroke Have regular medical checkups. know our: • blood pressure • blood sugar • cholesterol level …SLE might not have a cure, but it's a highly treatable condition. Take our medications
- 34. Lifestyle Changes forLupus Eat a healthy diet. Exercise. Rest. Reduce stress.
- 35. Remember.. “ Work withour doctors.. because lupus is always unpredictable and our symptoms are likely to fluctuate over time even with good treatment.” “ But with patience -- and the help of our health care team -- the odds are good that we'll find a lupus treatment plan that works for us.”
- 36. 80% to 90%of people with lupus can expect a normal lifespan with good treatment. Lupus Foundation of America,
- 39. THANK YOU FORYOUR KIND ATTENTION
Editor's Notes
- #8 Many people with lupus are unusually sensitive to the sun and other forms of ultraviolet light. A day at the beach may trigger a skin rash in areas exposed to sunlight and may worsen other lupus symptoms. Certain medications can make people with lupus even more sensitive to UV light. more than half of all people with lupus are light sensitive. More importantly, 40% to 70% of people with lupus experience an increase in lupus symptoms after being exposed to ultraviolet (UV) rays, either from the sun or from artificial light. Sunlight may cause also a lupus flare, resulting in fever, joint pain, or even organ inflammation.
- #9 Joint and muscle pain is often the first sign of lupus. This pain tends to occur on both sides of the body at the same time, particularly in the joints of the wrists, hands, fingers, and knees. The joints may look inflamed and feel warm to the touch. But unlike rheumatoid arthritis, lupus usually does not cause permanent joint damage.
- #10 A tell-tale sign of lupus is a butterfly-shaped rash across the cheeks and bridge of the nose. Other common skin problems include sensitivity to the sun with flaky, red spots or a scaly, purple rash on various parts of the body, including the face, neck, and arms. Some people also develop mouth sores.
- #11 Lupus can cause the nails to crack or fall off. They may be discolored with blue or reddish spots at the base. These spots are actually in the nail bed, the result of inflamed small blood vessels. Swelling may also make the skin around the base of the nail look red and puffy.
- #12 Most people with lupus experience some degree of fatigue. In many cases, it is severe enough to interfere with exercise and other daily activities. Most patients also run a low-grade fever from time to time. This unexplained fever may be the only warning sign in some people.
- #13 Some people with lupus develop a condition called Raynaud's phenomenon. Their fingers and toes become painful, numb, and tingly in response to cold temperatures or emotional stress. This happens when small blood vessels spasm and restrict blood flow to the area. During an attack, the fingers and toes may turn white or blue. People can also have Raynaud's without having lupus or any serious health complications.
- #14 The symptoms of lupus tend to come and go, and this includes hair loss. Patients may go through periods where their hair falls out in patches or becomes thinner all across the scalp. Once the flare-up is over, new hair is likely to grow back.
- #16 it affects women 10 times more often than men. Aside from being female, your odds of getting the disease are higher if you are: African-American, Latino, or Asian Between the ages of 20 and 40 Related to someone with lupus…in short.. Anyone can get lupus.
- #18 Up to three out of four people with lupus can develop kidney problems. These problems may not cause symptoms, though some people notice swelling in their legs or ankles. Most patients only learn about their kidney trouble when a urine test reveals blood or abnormal protein levels. The most common heart problem linked to lupus is an inflammation of the sac around the heart. This may cause severe pain in the left side of the chest. People with lupus are also more likely to develop plaques that narrow or clog the arteries. This can lead to coronary artery disease. Other complications include heart valve disease and inflammation of the heart muscle. Call 911 immediately for chest pain, rather than trying figure out the cause yourself.
- #19 Lupus and the medications used to treat it can contribute to anemia in some patients. This means the body has too few red blood cells, because it is not making enough, or red blood cells are being destroyed more quickly than they can be replaced. Symptoms include fatigue and shortness of breath.
- #20 And today we are going to focus our discussion on one of the most important complications of lupus.. STROKE For a brief overview..
- #21 Stroke is a medical emergency .It occurs when a blood vessel in the brain bursts or, more commonly, when a blockage develops. Without treatment, cells in the brain quickly begin to die. The result can be serious disability or death.
- #23 As ive mentioned before, in lupus, our bodies produce abnormal ANTIBODIES. One of the abnormal ab produced is an ANTIPHOSPHOLIPID ANTIBODY (APA). 1. APA attack membranes of the cells that line the inside of the blood vessel which initiates the formation of blood clots.. This could happen in the diff parts of the body ( deep veins of the legs, the heart and the head) Sometimes these blood clots can travel to the brain and cause embolic strokes. The incidence of stroke, heart attacks and TIAs are increase in pxs with SLE but are not exclusive to pxs with APAS.
- #26 2. In lupus, ANTIBODIES that attack our healthy tissues also cause inflammation inside the walls of blood vessels know as VASCULITIS. Sometimes the inflammation is so severe that blood flow is completely prevented. If this happens in the BRAIN…IT CAN LEAD TO STROKE.
- #27 Atherosclerosis also contributes to stroke where arteries are narrowed by plaque. Plaques can also be dislodged and cause embolism which can eventually lead to stroke.
- #28 Blood flow is temporarily impaired to part of the brain, causing symptoms similar to an actual stroke. When the blood flows again, the symptoms disappear. A TIA is a warning sign that a stroke may happen soon.
- #34 Even with good treatment, your symptoms are likely to fluctuate over time. Lupus is always unpredictable. That's why careful monitoring and regular check-ups are so important