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S ir C h r is
   R etired C hief E xecutive, Smith & N ephew
      O ’ D o n n e ll
F u t u r e M e d ic a l
 T e c h n o lo g ie s
   a n d D r iv e r s
F E S T IV A L
 S H E F F I E L D 2 0 12
                  Medical Technology
                Innovative high-value added
                 manufacturing technology
Sir Christopher O’Donnell
March 2012
1970’s                                              1990’s
• High speed clinical chemistry analyser            •Hydrocellular wound dressings
• Servo-control infant incubator                    • Lightweight fracture casting products
• Portable human isolation nursing system           • High vapour permeable IV dressings
                                                    • ‘Easy to use’ orthopaedic implant instruments

                                         Medical
                                        Technology
                                   Innovation – Personal
                                          History
1980’s                                               2000’s
• Infection control urinary catheter
                                                     • Tissue engineered wound dressings
• Integrated heart by-pass oxygenator
                                                     • Oxidised zirconium hips/knees
& tube packs
                                                     • Bio-resorbable arthroscopic fixation
                                                                 Sir Christopher O’Donnell – Sheffield 2012
Healthcare system demands
           innovation
M a r k e t d y n a m ic s   V a lu e a d d e d
                               in n o v a t io n s
• Demographics
• Active lifestyle           • Smarter materials
• Better-informed patients   • Less invasive (MIS) procedures
• Declining surgeon income   • Accelerated healing
• Nurse shortage             • Alternative therapies
• Healthcare Spending        • Faster patient turn-round
• Specialization             • Positive health economics
• New technologies           • Ease/convenience of use

                                     Sir Christopher O’Donnell – Sheffield 2012
Global Medical Technology
          Market by Region 2011




                       Global Market Value: $250bn
Source: Espciom 2011          Sir Christopher O’Donnell – Sheffield 2012
to innovate / differentiate
                       products
   1. D i f f e r e n c e s i n c u s t o m e r
      d e m a n d :-

       •       Levels of healthcare spend per capita

       •       Approval, procurement and reimbursement
               practices
Source: Arthur D Little/ DTI report 2004         Sir Christopher O’Donnell – Sheffield 2012
Factors affecting national ability to
        innovate / differentiate products
   Ø                 A c c e s s t o s c i e n t i f i c /c l i n i c a l
                     k n o w le d g e : -
              •         Varies according to maturity of technology
                                     Increasing Technology Maturity
              •         Clinicians have multiple linkages with innovation
                           Embryonic        Growth          Mature  Ageing

                        process
                                   IV Diagnostics
                                      reagents
                                                    Orthopaedics
       Market Size




                                    Active wound
                     First“product” management                           Imaging
                      breakthrough
                                 Advanced wound
                                                                   Elec.med/respiratory
                                                                      Radiotherapy
                                     management
                                       (Tissue
                                     engineering)

                                                                                                         Time

Source: Arthur D Little/ DTI report 2004                                                  Sir Christopher O’Donnell – Sheffield 2012
MedTech Innovation
•   Medical technology is a large and growing global
    industry

•   Innovation is the key driver of growth and is
    global in nature

•   Technology plays a major role in driving this
    innovation – but needs strong industry / clinician /
    health service collaboration to succeed
                                        Sir Christopher O’Donnell – Sheffield 2012
MedTech Sector in the UK
          UK                     Yorkshire Region


                         Companies - 150
Companies - 2,500+

                         Turnover - £1.8bn
Domestic Market - £6bn
                         Strengths - Woundcare
Exports - £5bn+                        Orthopaedic Devices
                                       Surgical Instruments
Employees - 50,000


                                             Sir Christopher O’Donnell – Sheffield 2012
Example of Innovation:
   Knee Joint Replacement

  SMITH & NEPHEW
     GENESIS II

      Knee System
with Oxinium™ Technology
                           Sir Christopher O’Donnell – Sheffield 2012
OXINIUM™ – a major innovation
      in reducing wear
    •     Ceramic is generally accepted as the ideal bearing surface for total
          joints but has strength limitations
•       For more than 15 years Smith & Nephew worked to develop an innovative
        material that combines the benefits of ceramic with the strength of metal
•       The result OXINIUM™, a metal with an integral ceramic surface

•       Performing clinically equivalent to or better than conventional alternative Cobalt
        Chrome
•       In the Laboratory OXINIUM™ wear at 30 years is less than Cobalt Chrome at 3
        years


                                                                 Sir Christopher O’Donnell – Sheffield 2012
Manufacturing Process Development
Process                         Issues
Define & Prove
     Alloy                     Biocompatibility

 Scale Up and                  Small scale novel alloy
Prove Smelting


  Net Shape                    No other Manufacturer
   Forging                     forges Zirconium

  Shaping &                   Zirconium dust combusts
   Grinding
   Process                    spontaneously and burns at 3,000°C

 Finishing &                   Completely novel mirror
  Polishing
 Processes                     finish requirements
                                                    Sir Christopher O’Donnell – Sheffield 2012
innovation
M a r k e t d y n a m ic s           O X IN IU M
• Demographics                       • Smarter materials
• Active lifestyle                   • Less invasive (MIS) procedures
• Better-informed patients           • Accelerated healing
• Declining surgeon income           • Alternative therapies
• Nurse shortage                     • Faster patient turn-round
• Healthcare Spending                • Positive health economics
• Specialization                     • Ease/convenience of use
• New technologies

                                             Sir Christopher O’Donnell – Sheffield 2012
More Information?
•   INDUSTRY OVERVIEW
    Strengths and Opportunity: Annual Update Dec 2011
    HMG; www.bis.gov.uk

•   LOCAL INDUSTRY NETWORK/ASSISTANCE
    Medilink Yorkshire & Humber Ltd
    www.medilink.co.uk
    Telephone: 01142 329200

•   INNOVATION IN THE HEALTH SERVICE
    Devices for Dignity (D4D) Healthcare Technology Co-Operative
    Sheffield Teaching Hospital
    www.devicesfordignity.org.uk                       Sir Christopher O’Donnell – Sheffield 2012
F E S T IV A L
 S H E F F I E L D 2 0 12
                  Medical Technology
                Innovative high-value added
                 manufacturing technology
Sir Christopher O’Donnell
March 2012

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Sir chris odonnel

  • 1. S ir C h r is R etired C hief E xecutive, Smith & N ephew O ’ D o n n e ll F u t u r e M e d ic a l T e c h n o lo g ie s a n d D r iv e r s
  • 2. F E S T IV A L S H E F F I E L D 2 0 12 Medical Technology Innovative high-value added manufacturing technology Sir Christopher O’Donnell March 2012
  • 3. 1970’s 1990’s • High speed clinical chemistry analyser •Hydrocellular wound dressings • Servo-control infant incubator • Lightweight fracture casting products • Portable human isolation nursing system • High vapour permeable IV dressings • ‘Easy to use’ orthopaedic implant instruments Medical Technology Innovation – Personal History 1980’s 2000’s • Infection control urinary catheter • Tissue engineered wound dressings • Integrated heart by-pass oxygenator • Oxidised zirconium hips/knees & tube packs • Bio-resorbable arthroscopic fixation Sir Christopher O’Donnell – Sheffield 2012
  • 4. Healthcare system demands innovation M a r k e t d y n a m ic s V a lu e a d d e d in n o v a t io n s • Demographics • Active lifestyle • Smarter materials • Better-informed patients • Less invasive (MIS) procedures • Declining surgeon income • Accelerated healing • Nurse shortage • Alternative therapies • Healthcare Spending • Faster patient turn-round • Specialization • Positive health economics • New technologies • Ease/convenience of use Sir Christopher O’Donnell – Sheffield 2012
  • 5. Global Medical Technology Market by Region 2011 Global Market Value: $250bn Source: Espciom 2011 Sir Christopher O’Donnell – Sheffield 2012
  • 6. to innovate / differentiate products 1. D i f f e r e n c e s i n c u s t o m e r d e m a n d :- • Levels of healthcare spend per capita • Approval, procurement and reimbursement practices Source: Arthur D Little/ DTI report 2004 Sir Christopher O’Donnell – Sheffield 2012
  • 7. Factors affecting national ability to innovate / differentiate products Ø A c c e s s t o s c i e n t i f i c /c l i n i c a l k n o w le d g e : - • Varies according to maturity of technology Increasing Technology Maturity • Clinicians have multiple linkages with innovation Embryonic Growth Mature Ageing process IV Diagnostics reagents Orthopaedics Market Size Active wound First“product” management Imaging breakthrough Advanced wound Elec.med/respiratory Radiotherapy management (Tissue engineering) Time Source: Arthur D Little/ DTI report 2004 Sir Christopher O’Donnell – Sheffield 2012
  • 8. MedTech Innovation • Medical technology is a large and growing global industry • Innovation is the key driver of growth and is global in nature • Technology plays a major role in driving this innovation – but needs strong industry / clinician / health service collaboration to succeed Sir Christopher O’Donnell – Sheffield 2012
  • 9. MedTech Sector in the UK UK Yorkshire Region Companies - 150 Companies - 2,500+ Turnover - £1.8bn Domestic Market - £6bn Strengths - Woundcare Exports - £5bn+ Orthopaedic Devices Surgical Instruments Employees - 50,000 Sir Christopher O’Donnell – Sheffield 2012
  • 10. Example of Innovation: Knee Joint Replacement SMITH & NEPHEW GENESIS II Knee System with Oxinium™ Technology Sir Christopher O’Donnell – Sheffield 2012
  • 11. OXINIUM™ – a major innovation in reducing wear • Ceramic is generally accepted as the ideal bearing surface for total joints but has strength limitations • For more than 15 years Smith & Nephew worked to develop an innovative material that combines the benefits of ceramic with the strength of metal • The result OXINIUM™, a metal with an integral ceramic surface • Performing clinically equivalent to or better than conventional alternative Cobalt Chrome • In the Laboratory OXINIUM™ wear at 30 years is less than Cobalt Chrome at 3 years Sir Christopher O’Donnell – Sheffield 2012
  • 12. Manufacturing Process Development Process Issues Define & Prove Alloy Biocompatibility Scale Up and Small scale novel alloy Prove Smelting Net Shape No other Manufacturer Forging forges Zirconium Shaping & Zirconium dust combusts Grinding Process spontaneously and burns at 3,000°C Finishing & Completely novel mirror Polishing Processes finish requirements Sir Christopher O’Donnell – Sheffield 2012
  • 13. innovation M a r k e t d y n a m ic s O X IN IU M • Demographics • Smarter materials • Active lifestyle • Less invasive (MIS) procedures • Better-informed patients • Accelerated healing • Declining surgeon income • Alternative therapies • Nurse shortage • Faster patient turn-round • Healthcare Spending • Positive health economics • Specialization • Ease/convenience of use • New technologies Sir Christopher O’Donnell – Sheffield 2012
  • 14. More Information? • INDUSTRY OVERVIEW Strengths and Opportunity: Annual Update Dec 2011 HMG; www.bis.gov.uk • LOCAL INDUSTRY NETWORK/ASSISTANCE Medilink Yorkshire & Humber Ltd www.medilink.co.uk Telephone: 01142 329200 • INNOVATION IN THE HEALTH SERVICE Devices for Dignity (D4D) Healthcare Technology Co-Operative Sheffield Teaching Hospital www.devicesfordignity.org.uk Sir Christopher O’Donnell – Sheffield 2012
  • 15. F E S T IV A L S H E F F I E L D 2 0 12 Medical Technology Innovative high-value added manufacturing technology Sir Christopher O’Donnell March 2012