This study used the CROPWAT model to simulate the effects of temperature changes on maize crop yields in Ibadan, Nigeria. The results showed that rising temperatures had a negative effect on maize yields, though the reduction trends were not definite due to variability in temperatures. Yield reductions were low under definite interval irrigation and high without irrigation. Definite interval irrigation was determined to be the most effective strategy to minimize yield losses from temperature increases and weather variability.