The sense of touch or mechanoreception allows organisms to perceive qualities of objects and environments such as pressure, temperature, roughness or smoothness, hardness, etc. In humans it is considered one of the five basic senses. Tactile sensitivity is divided into two types - protopathic and epicritic - which follow different sensory pathways to the encephalon. The skin contains various tactile receptors such as Meissner's corpuscles, Pacini corpuscles, Ruffini corpuscles, and Krause end-bulbs that allow us to perceive different tactile sensations like pressure, temperature, pain, and form/texture. Diseases or defects of the tactile sense include leprosy, cuts, burns, and