P. Ricci, G. M. Verderame, G. Manfredi, M. Pollino, F. Borfecchia, L. De Cecco, S. Martini, C. Pascale, E. Ristoratore and V. James (2011). Presented at "Computational Science and Its Applications - ICCSA 2011 International Conference", Santander, Spain, June 20-23, 2011. In this presentation, a seismic vulnerability assessment at large scale is described, within the SIMURAI project. A field survey was carried out in order to gather detailed information about geometric characteristics, structural typology and age of construction of each single building. An airborne Remote Sensing (RS) mission was also carried out over the municipality of Avellino, providing a detailed estimate of 3D geometric parameters of buildings through a quite fast and easy to apply methodology integrating active LIDAR technology, aerophotogrammetry and GIS techniques. An analytical seismic vulnerability assessment procedure for Reinforced Concrete buildings is illustrated and applied to the building stock considering (i) field survey data (assumed as a reference) and (ii) LIDAR data combined with census data as alternative sources of information, according to a multilevel approach. A comparison between the obtained results highlights an acceptable scatter when data provided by RS techniques are used.