Atopic dermatitis (AD) is one of the most common skin disorders seen in children. The cutaneous manifestations of atopy often represent the onset of the atopic journey gradually marching towards asthma and allergic rhinitis. Difficult to control AD presents a therapeutic challenge in today’s era. But constitutional homoeopathic medicines prescribed singly in its potentised form definitely benefit the patient.
Two randomly diagnosed cases of AD have been discussed who opted for treatment after relapse and remission of skin lesions under prolonged allopathic treatment. Both cases complained of intense pruritic painful eruptions all over the body. The first case was of a male child aged 3yrs who also had hyperpyrexia which was controlled with Arnica followed by prescription of single dose of Nitric acid. The second case was a female child of 10yrs who was prescribed Hepar sulph in 30 potency initially followed by 200. Prescription was based on totality of symptoms. The assessment of outcome was judged on change in pruritus, AD extension and severity, general and psychological wellbeing.
Comparison of affected skin area between first and last consultation showed significant improvement clinically.
These cases suggest that homoeopathic treatment could be contemplated as an effective choice for patients with AD.
It is important for all of us to work more meticulously, on modern scientific parameters, creating enough documentary proofs as per the need of the hour, without jeopardizing the tenets of Homoeopathy, so that our studies leave no gaps when such analyses are repeated.
Tips and tricks to learn 120+ homoeopathic remedies just within one hour - By...Dr.hansraj salve
Tips and tricks to learn 120+ homoeopathic remedies just within one hour that you never imagined before - By Dr. Hansaraj salve.
Definition - Study of a number of similar homeopathic remedies which poses similar structure, properties and characteristics considered together related in certain groups like acid group, metal group, carbon group etc.
Group study is first step to understand each remedy in its entity
Save lot of time and energy to remember and learn materia medica.
It is always advantageous to learn particular group characteristics and structural elements of the group first and then study group members which can make learning procedure easy and fun and this will help you in easy understanding of similarities and differences between group members and other remedies(comparative study of materia medica).
for more details visit https://goo.gl/G0dC1o
Homoeopathic materia medica group study - Carbon group slide show presentatio...Dr.hansraj salve
Simplest and easiest way to learn and remember materia medica drugs is group study of homoeopathic materia medica this is a demo for our students and practitioner for there reference if you like share with your friends. for complete understanding watch slide show presentation now!!!
Tips and tricks to learn 120+ homoeopathic remedies just within one hour - By...Dr.hansraj salve
Tips and tricks to learn 120+ homoeopathic remedies just within one hour that you never imagined before - By Dr. Hansaraj salve.
Definition - Study of a number of similar homeopathic remedies which poses similar structure, properties and characteristics considered together related in certain groups like acid group, metal group, carbon group etc.
Group study is first step to understand each remedy in its entity
Save lot of time and energy to remember and learn materia medica.
It is always advantageous to learn particular group characteristics and structural elements of the group first and then study group members which can make learning procedure easy and fun and this will help you in easy understanding of similarities and differences between group members and other remedies(comparative study of materia medica).
for more details visit https://goo.gl/G0dC1o
Homoeopathic materia medica group study - Carbon group slide show presentatio...Dr.hansraj salve
Simplest and easiest way to learn and remember materia medica drugs is group study of homoeopathic materia medica this is a demo for our students and practitioner for there reference if you like share with your friends. for complete understanding watch slide show presentation now!!!
Introduction to the concordance repertoriesdrmohitmathur
The presentation discusses the fundamental concept of concordance repertories. The framework, merits and demerits of Gentry concordance repertory and Repertory of Hering’s Guiding Symptoms of our Materia Medica by Calvin B.Knerr are described in detail.
Eczema - A Case Presentation (by Dr. Julius King Kwedhi)Dr. Julius Kwedhi
Eczema: Come from the Greek name for boiling, a reference to the tiny vesicles (bubbles) that are commonly seen in the early acute stage of the disease
An immune-mediated inflammation of the skin arising from an interaction between genetic (e.g. epidermal barrier function, immune system) and environmental factors (foods, airborne allergens, Staphylococcus aureus colonization on skin due to deficiencies in endogenous antimicrobial peptides, topical products)
The eczemas are a disparate group of diseases, but unified by the presence of itch and, in the acute stages, of oedema (spongiosis) in the epidermis
Helleborus Niger homoeopathic materia medica slide show presentation by Dr. H...Dr.hansraj salve
Watch the symptoms you never saw before SLEEPINESS WITH EYES HALF OPEN PUPILS
TURNED UPWARD_HELLEBORUS N
SMELL DIMINISHED_HELLEBORUS N
SMELL HORRIBLE FROM MOUTH_HELLEBORUS
N
STAGGERING GAIT WANT FIRMNESS IN LEGS
BENDING OF KNEES_HELLEBORUS N
STARTING FROM COMATOSE
SLEEP_HELLEBORUS N
STIFFNESS AND TENSION OF THE MUSCLES OF
THE THIGH_HELLEBORUS N
STIFFNESS IN THE HOLLOWS OF THE
KNEES_HELLEBORUS N
STIFFNESS OF CERVICAL MUSCLES_HELLEBORUS
N
STUPEFACTION AND
SLUGGISHNESS_HELLEBORUS N
STUPEFACTION OF THE BODY AND
MIND_HELLEBORUS N
STUPID ANSWER SLOWLY WHEN
QUESTIONED_HELLEBORUS N
STUPOR WITH UNEQUAL PUPILS_HELLEBORUS
N
SUDDEN DROPSICAL SWELLING OF SKIN MANY
DISEASES_HELLEBORUS N
SUDDEN PARALYTIC STIFFNESS IN THE LEFT HIP
JOINT_HELLEBORUS N
Understanding Natrum group with elaboration of Natrum Muriaticum personality from Homoeopathic Materia Medica
By Dr. Namrata Bosamia Surati B.H.M.S., M. D. (HOM.)
homeopathy is one of effective system of medicine founded by Dr.Samuel Hahnemann.
It is based on the principle Like cures Like.
My ppt is about the homeopathic law of cure given in §25- §29 and how a homeopathic medicine works. :)
Scope of homoeopathic medicines in atopic dermatitissmita brahmachari
SCOPE OF HOMOEOPATHIC MEDICINES IN ATOPIC DERMATITIS
Dr.Smita Brahmachari
Atopic dermatitis (AD), one of the most common skin disorders seen in infants and children, usually has its onset during the first 6 months of life. AD has a tremendously negative effect on the quality of life of patients as well as family, most commonly disturbing sleep. The condition also creates a great financial burden for both the family and society. The cutaneous manifestations of atopy often represent the beginning of the atopic march. On the basis of several longitudinal studies, approximately half of AD patients will develop asthma, particularly with severe AD, and two thirds will develop allergic rhinitis. Difficult to control atopic dermatitis (AD) presents a therapeutic challenge in today’s era. The present article discusses how homoeopathy can be used as a safe and alternative treatment for such cases at primary health care set up.
Introduction to the concordance repertoriesdrmohitmathur
The presentation discusses the fundamental concept of concordance repertories. The framework, merits and demerits of Gentry concordance repertory and Repertory of Hering’s Guiding Symptoms of our Materia Medica by Calvin B.Knerr are described in detail.
Eczema - A Case Presentation (by Dr. Julius King Kwedhi)Dr. Julius Kwedhi
Eczema: Come from the Greek name for boiling, a reference to the tiny vesicles (bubbles) that are commonly seen in the early acute stage of the disease
An immune-mediated inflammation of the skin arising from an interaction between genetic (e.g. epidermal barrier function, immune system) and environmental factors (foods, airborne allergens, Staphylococcus aureus colonization on skin due to deficiencies in endogenous antimicrobial peptides, topical products)
The eczemas are a disparate group of diseases, but unified by the presence of itch and, in the acute stages, of oedema (spongiosis) in the epidermis
Helleborus Niger homoeopathic materia medica slide show presentation by Dr. H...Dr.hansraj salve
Watch the symptoms you never saw before SLEEPINESS WITH EYES HALF OPEN PUPILS
TURNED UPWARD_HELLEBORUS N
SMELL DIMINISHED_HELLEBORUS N
SMELL HORRIBLE FROM MOUTH_HELLEBORUS
N
STAGGERING GAIT WANT FIRMNESS IN LEGS
BENDING OF KNEES_HELLEBORUS N
STARTING FROM COMATOSE
SLEEP_HELLEBORUS N
STIFFNESS AND TENSION OF THE MUSCLES OF
THE THIGH_HELLEBORUS N
STIFFNESS IN THE HOLLOWS OF THE
KNEES_HELLEBORUS N
STIFFNESS OF CERVICAL MUSCLES_HELLEBORUS
N
STUPEFACTION AND
SLUGGISHNESS_HELLEBORUS N
STUPEFACTION OF THE BODY AND
MIND_HELLEBORUS N
STUPID ANSWER SLOWLY WHEN
QUESTIONED_HELLEBORUS N
STUPOR WITH UNEQUAL PUPILS_HELLEBORUS
N
SUDDEN DROPSICAL SWELLING OF SKIN MANY
DISEASES_HELLEBORUS N
SUDDEN PARALYTIC STIFFNESS IN THE LEFT HIP
JOINT_HELLEBORUS N
Understanding Natrum group with elaboration of Natrum Muriaticum personality from Homoeopathic Materia Medica
By Dr. Namrata Bosamia Surati B.H.M.S., M. D. (HOM.)
homeopathy is one of effective system of medicine founded by Dr.Samuel Hahnemann.
It is based on the principle Like cures Like.
My ppt is about the homeopathic law of cure given in §25- §29 and how a homeopathic medicine works. :)
Scope of homoeopathic medicines in atopic dermatitissmita brahmachari
SCOPE OF HOMOEOPATHIC MEDICINES IN ATOPIC DERMATITIS
Dr.Smita Brahmachari
Atopic dermatitis (AD), one of the most common skin disorders seen in infants and children, usually has its onset during the first 6 months of life. AD has a tremendously negative effect on the quality of life of patients as well as family, most commonly disturbing sleep. The condition also creates a great financial burden for both the family and society. The cutaneous manifestations of atopy often represent the beginning of the atopic march. On the basis of several longitudinal studies, approximately half of AD patients will develop asthma, particularly with severe AD, and two thirds will develop allergic rhinitis. Difficult to control atopic dermatitis (AD) presents a therapeutic challenge in today’s era. The present article discusses how homoeopathy can be used as a safe and alternative treatment for such cases at primary health care set up.
My Dear Colleagues and Friends
Hi. I would like to present my poster, that became the number one poster at the 69th LMHI Congress in Paris, 2014.
It is on homeopathic healing of patient with allergic constitution.
Best of luck,
Dr.Sadeghi
"Explore 'Allergy Treatment in Homeopathy'—uncover gentle yet powerful principles alleviating allergies naturally. Understand allergy roots, discover personalized remedies, and integrate homeopathy seamlessly into your wellness routine. Unravel the science and art of homeopathic allergy treatment, gaining knowledge and tools for a healthier, balanced life naturally. Join us on this transformative journey."
Blisters and homeopathy: case reports and differential diagnosishome
Blisters are skin lesions characterized by accumulation of fluid between the layers of the
skin. Their severity varies from the common blisters caused by friction to severe autoimmune
and congenital bullous disorders, some of themcurrently without treatment in conventional
medicine or requiring drugs with potentially severe side-effects. This article
reports cases of blistering diseases successfully treated with homeopathic medicines,
which represent an alternative for the treatment of such disorders.
It's all about the Animal(Snake,Scorpion,Spider)Plant(Mushroom).In our basic need we will face this type of animal and plant that's why the general people should knows about it.
Hepar sulph homoeopathic materia medica slide show presentation by Dr. Hansar...Dr.hansraj salve
Some important symptoms of hepar sulph you will never see in your whole life. ABDOMEN DISTENDED BY FLATULENCE
TIGHTNESS_HEPER SULPH
ABDOMEN SWOLLEN OBSTINATE
CONSTIPATION_HEPER SULPH
In the recent years, there is a rise in the number of people suffering from piles, a condition medically termed as Haemorrhoids. Since time immemorial haemorrhoids have plagued humankind, yet many misunderstandings regarding haemorrhoidal complaints and disease still exist. Proportionately, there is a hike in the advertisements in different media on various patent products that are supposed to cure piles. But the fact is, majority of the piles patients we come across are self diagnosed cases. Most of them suffer from occasional burning pains or soreness in the anal region and diagnose themselves as piles without a medical consultation. Thereafter, they go on taking patent preparations over the counter without a doctor’s prescription. The present article focuses on homoeopathic approach to a case of haemorrhoids.
ABSTRACT FOR CONSTITUTIONAL PRESCRIPTION IN PAEDIATRIC CASES
It has been said that child is the father of man. By caring for the health of the child, right from its conception and removing hereditary taints and carrying it through a period of as good health as may be possible by us by use of homoeopathic system of medicine, we can build up a new generation of comparatively less ‘sick’ people. Many of the most common illnesses of childhood can be effectively treated with homeopathic medicines. And thus Homeopathy is gaining recognition in the conventional field of medicine and has been subject to many clinical trials. Homeopathy is ideal for babies and children as it is a gentle yet highly effective. Children respond wonderfully to simple homeopathic remedies. The mildly sweet pills, powders or liquids are easy to dispense and are more palatable than many conventional medicines. The present article focuses on how to approach a paediatric case and ultimately reach the homoeopathic similimum.
http://www.slideshare.net/smitabrahmachari/abstract-for-constitutional-prescribing-in-paediatric-cases.
Polycystic ovary syndrome (PCOS) is of clinical and public health importance as it is very common in today’s era affecting women of reproductive age group. It has significant and diverse clinical implications including reproductive (infertility, hyperandrogenism, hirsutism), metabolic (insulin resistance, impaired glucose tolerance, type 2 diabetes mellitus, adverse cardiovascular risk profiles) and psychological features (increased anxiety, depression and worsened quality of life).
Another commonest ovarian disorder is ovarian cyst. The treatment of an ovarian cyst relies on its nature, and accurate preoperative discrimination of benign and malignant cysts is therefore of crucial importance.
In a regular Homoeopathic OPD the physician today encounter these two cases frequently. Most of the patients visiting with these disorders opt for Homoeopathy as an alternative treatment option to revert surgical procedures, or after failed hormonal therapies.
Homoeopathic management should focus on education, addressing psychological factors and strongly emphasizing healthy lifestyle with targeted medical therapy as required.
The present article discusses on various aspects of these ovarian disorders. Cases of Ovarian disorders which were successfully treated with homoeopathic medicines by the author are reported here.
Dr. Smita Brahmachari
M.O., Dept. of AYUSH, Govt. of NCT Delhi.
Allergic rhinitis is a very common disorder that affects people of all ages. It is frequently ignored, under diagnosed, misdiagnosed, and mistreated, which not only is detrimental to health but also has societal costs. Although allergic rhinitis is not a serious illness, it is clinically relevant because it underlies many complications, is a major risk factor for poor asthma control, and affects quality of life and productivity at work or school. Hidden direct costs include the treatment of co-morbid asthma, chronic sinusitis, otitis media, upper respiratory infection, and nasal polyp. Nasal congestion, the most prominent symptom in AR, is associated with sleep-disordered breathing, a condition that can have a profound effect on mental health, including increased psychiatric disorders, depression, anxiety, and alcohol abuse. Furthermore, sleep-disordered breathing in childhood and adolescence is associated with increased disorders of learning performance, behavior, and attention. Management of allergic rhinitis is best when directed by guidelines. At this juncture Homoeopathic system of medicine offers a safe and effective solution of the illness if followed under the guidance of expertise. This article provides an overview of the patho-physiology, diagnosis, and appropriate homoeopathic management of this disorder.
Dr. Smita Brahmachari
M.O., Dept. of AYUSH, Govt. of NCT Delhi.
ANALYTICAL REPERTORY OF THE SYMPTOMS OF THE MIND
Dr. Smita Brahmachari
The practice of Homoeopathy is a balancing act. We weigh pros and cons to arrive at a prescription; for us differential diagnosis is not only for identifying the disease but also for identifying the drug. In such identification process we gather all the symptoms of the patient, without a prejudiced eye. We do not judge the patient or censor his sayings for we very well know the importance of each and every symptoms – whether it is a mental or a physical symptom. Mental symptoms were used for the final deciding vote rather than for initial identification of medicines, except in a few exceptional cases. Pioneer homoeopaths had this approach to practice that the Mind and Body are not separate but are only different manifestations of the same vital force.
The need for such a repertory where the mental concomitants of physical complaints and physical concomitants of mental states are available has been met in Dr.C.Hering’s ANALYTICAL REPERTORY OF THE SYMPTOMS OF THE MIND. This book contains those symptoms of the mind that have been observed in connection with the bodily symptoms. This book is not a collection of mental symptoms as in Synthetic Repertory, Vol-I. Hering being an ardent follower of Hahnemann wanted to revive Hahnemannian concept back into Homoeopathic practice. So, at the end of the ‘Introduction’, he says that through this work, the future Homoeopaths will be able to follow the right way of the true Hahnemannian school, i.e. always to individualize.
This is a humble attempt on my part to represent this work of Hering. I have used this book in the OPD only a few times but after going through the whole work, the potentiality of this book can definitely be felt. We all must try to use this book and establish the role it can play in our daily practice.
ABSTRACT:
Nocturnal enuresis or night time urinary incontinence, commonly called bedwetting or sleep wetting, is involuntary urination while asleep after the age at which bladder control usually occurs. Bedwetting is a common childhood urologic complaint and one of the most common pediatric health issues. Enuresis is notoriously difficult to treat and is frequently related to psychological factors. The emotional impact of enuresis on a child and family is considerable. Children with enuresis are commonly punished and are at risk for emotional and physical abuse. Numerous studies of children with enuresis report feelings of embarrassment and anxiety, loss of self-esteem, and effects on self-perception, interpersonal relationships, quality of life, and school performance. The condition can be successfully treated with homoeopathic medicines but require a long term follow – up. The present article focuses on management of this medical condition with our medicines.
A SYNOPTIC KEY OF THE MATERIA MEDICA
Dr. Smita Brahmachari
Correct prescribing is the art of carefully fitting pathogenetic to clinical symptoms, and such at present requires a special aptness in grasping the essential points of symptom images, great drudgery, mastering a working knowledge of our large materia medica and a most skillful use of many books of reference. It is the aim of this book “A Synoptic Key of the Materia Medica” is to simplify and introduce method into this work, so that the truly homoeopathic curative remedy may be worked out with greater ease and certainty.
SYSTEMIC HYPERTENSION AND SCOPE OF HOMOEOPATHY
Dr. Smita Brahmachari
Abstract:
Hypertension (HTN) is an enormous health problem and is one of the biggest health challenges in the 21st century. Although the condition is common, readily detectable, and easily treatable, it is usually asymptomatic and often leads to lethal complications if left untreated. The prevalence of HTN is increasing rapidly in India driven by diverse health transitions. Apart from health implications it has huge societal, developmental and economic costs to resource constrained health systems, particularly developing nations like India. Further, hypertension is also a leading cause for hospitalizations and outpatient visits.
Reducing systolic and diastolic BP can decrease cardiovascular risk and this can be achieved by non-pharmacological (lifestyle measures) as well as pharmacological means (medicines). Homoeopathic system of medicine particularly individualized constitutional approach has significant beneficial effects on patients suffering from HTN and thus widely used in length and breadth of our nation as an alternative public health approach in curbing the increasing prevalence of HTN because of its cost effectiveness and minimal side effects.
In current scenario with rising burden of HTN posing a serious health threat to health care system of India, the present article makes a sincere attempt to present before its readers how to timely and effectively address a case of HTN at primary level health care set-up with homoeopathic medicines.
Author : The author has done her post-graduation from National Institute of Homoeopathy, Kolkata in the subject Homoeopathic Repertory. She is presently working as Medical Officer in Dept. of ISM &Homoeopathy under Govt. of NCT Delhi.
E-mail id: smita.brahmachari@rediffmail.com.
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
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NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
SCOPE OF HOMOEOPATHIC MEDICINES IN ATOPIC DERMATITIS
1. Dr. Smita Brahmachari,
M.D. (Repertory) (N.I.H., Kolkata)
Senior Medical Officer,
Dept. of AYUSH,
Govt. of NCT Delhi.
SCOPE OF HOMOEOPATHIC MEDICINES
IN ATOPIC DERMATITIS
2. Atopic dermatitis (AD) is one of the
most common skin disorders seen in
children.
The cutaneous manifestations of atopy
often represent the onset of the atopic
journey gradually marching towards
asthma and allergic rhinitis.
Difficult to control AD presents a
therapeutic challenge in today’s era.
3. AD is a chronic, itchy and inflammatory
skin disease caused by the interaction
between susceptible genes, environment,
drug reactions, skin barrier defects, and
immunological factors.
Included under scaling lesions in
dermatological disorders (ICD-10…L20).
Onset in childhood in most patients. Onset
after age of 30 is very uncommon.
4. Pruritus.
Chronic relapsing character of
the disorder.
Age-specific morphology.
Distribution of lesions (flexural
lichenification, hand eczema,
nipple eczema and eyelid eczema
in adults).
5. Also helpful are :
A personal or family history of
atopic disease (asthma, allergic
rhinitis, atopic dematitis),
Xerosis – ichthyosis
Facial pallor with infraorbital
darkening
Elevated serum IgE and
Eosinophilia.
Repeated skin infections.
6. CASE NO.1…….Presenting COMPlaints
A male child of three years.
Date of 1st visit: 6th December 2013
Severe pruritic painful eruptions all over the body with thick
scab formation.
Weeping and crusting of eruptions at various places especially
face and scalp with swelling of face.
Eruptions on trunk and extremities were dry, scaly and
thickened.
Father reported that he cried when combing his hair and while
urinating complaining burning micturition.
Complaint started at 6 months of age in month of May 2010.
Eruptions have aggravated since 15 days.
8. OBSERVATION
Child was undernourished, dark complexioned,
yellowish discolorization of sclera, brownish
discolorization of hair and scalp full of eruptions.
Child was very irritable, became restless on close
examination of his eruptions, but sat quietly in his
father’s lap.
Child was totally covered up, could not bear being
slightly uncovered as his eruption become more
painful and cried on being exposed to open air. His
father had brought the child to dispensary by
keeping even his face being covered up with a
shawl.
9. PAST HISTORY AND MEDICAL HISTORY
Great liability to take cold and suffers from recurrent attack of
cough and cold and need multiple nebulization for asthmatic
episodes.
Admitted in RML Hospital on 14th February 2013 with diagnosis
of Atopic dermatitis, eosinophilia and UTI induced
hypertension.
ULTRASONOGRAPHY report….intusseception with multiple
lymphadenopathy
HAEMOGRAM….microcytic, hypochromic anaemia with
anisopoikilocytosis, leucocytosis, tear drop cells and
eosinophilia.
H/o of recurrent cystitis.
He was discharged from hospital in a stabilized condition with
prescription of ointment for local application and antihistamine
(cetrizine). Since then he is regularly taking the prescribed medicine.
11. PHYSICAL GENERALS
Desire…potatoes, salt, and pickles
Aversion….vegetables.
Appetite… good but as soon as he started eating feels
nauseated after few mouthfuls.
Bowel habits….regular and 3-4 stools a day. He had urge
for stool during eating and passed after meals.
Perspiration ….normally from scalp and face.
Offensive stool and urine .
Disliked bathing and uncovering as it increased pain and
caused violent itching, burning and scratching all over
the body.
12. MENTAL GENERALS
He liked solitude, played with his own
toys alone and closes the door if any
neighbourhood child comes to play with
him.
Very irritable.
Dislikes to speak or to be spoken. Sits
quietly in father’s lap.
Fear when being touched or approached.
13. EVALUATION OF SYMPTOMS
The case presents with strong
generals and characteristic
particulars and hence Kent’s
method of evaluation of
symptoms was followed in this
case. Synthesis Repertory (9.1)
version was used for
repertorization.
14. RUBRIC SELECTION
MIND - IRRITABILITY - spoken to, when
GENERALS - HEAT - lack of vital heat
GENERALS - DISCHARGES - offensive, fetid
GENERALS - IRRITABILITY, physical - excessive
GENERALS - FOOD and DRINKS - salt - desire
GENERALS - FOOD and DRINKS - potatoes - desire
GENERALS - FOOD and DRINKS - vegetables -
aversion
SKIN - INFLAMMATION
STOMACH - NAUSEA - eating - while
BLADDER - URINATION - dysuria - painful
16. PRESCRIPTION…06.12.13
Medicine selected: Sulphur 30/1 dose.
Justification: the child was under the repeated
and prolonged use of skin ointments as local
application for eruptions since the onset of
complaint.
Remedy reaction: On the very second day after
taking Sulphur 30, there was onset of fever with
chilliness < night esp. at 12 – 1 am, thirsty
during fever, waked up 4 times to drink water,
was very irritable, shivering all over the body, at
the same time heat of the head and cool hands
and feet.
17. PRESCRIPTION….08.12.13
Medicine selected: Arnica 30 in 9 doses, thrice daily for 3 days and
later followed by placebo for 7 days.
Reason for selection: The rubric taken into consideration for
prescribing from SYNTHESIS REPERTORY was…‘FEAR,
approaching him, of others, lest he be touched’ (single
medicine…ARNICA in highest grade).
Not to be forgotten other valuable guiding symptoms further
confirming Arnica were :
Difference of temperature in various parts of body (heat of the
head and cool hands and feet)
Sensitiveness of whole body and
Weeping skin eruptions with symmetrical distribution.
Remedy reaction: Responded very well to Arnica and fever subsided
with improvement in skin condition.
20. PRESCRIPTION…NITRIC ACID
After continuing Arnica for few days, the patient reverted back to its
original state with complaints of….nausea while eating, irritableness
increased, relapse and remission of febrile condition with mid night
aggravation and skin symptoms reverting back to original condition,
anorexia, frequency of stool increased to 4 – 5 times, defecating
immediately and during meals.
The basis for prescription were :
Chilly patient,
Disposed to gastroenteritis,
Discharges being offensive (urine and feces),
Craving for salty food
Equally worse in hot and cold weather
Excessive irritableness of mind and physical complaints.
2nd medicine in repertorization. (highest marks)
21. PRESCRIPTION…(23.12.13)
Medicine selected: NITRIC ACID, the trimiasmatic polycrest
medicine, single dose.
Remedy reaction: no appearance of fever after taking Acid
nit and patient as a whole is very much better. At initial
visit he never responded at any question I asked him, sat
quietly and but later after taking Nitric acid he has started
answering by nodding his head and his parents say also that
his mental irritableness has decreased.
Change of potency: After continuing Nit acid 200 till 1st
February, the patient showed a stand still condition. So now
the prescription was changed to Nitric acid 1M, single dose
(01.02.14) and the patient till date is on placebo showing
improvement.
24. Case No.2
A female child of 10 yrs.
Date of 1st visit : 4.2.11.
A diagnosed case of Atopic dermatitis from Safdarjung
hospital, New delhi.
Painful, violent itching, burning eruptions all over the body
since 2 yrs.
< winter and summer especially hot humid weather; <
bathing after.
Eruptions were bilateral symmetrical.
H/o of use of lutica lotion on affected parts, steroid
ointments and antihistamines for 2 yrs with relapse and
remission of complaint.
26. Case No.2 (contd.)
Past H/O : Measles. Recurrent tendency to cough,
coryza and A.S.O.M. from change of weather
Family H/o : Mother – Asthma and Brother –
Crigler – Najjar syndrome (unconjugated
hyperbilirubinemia)
P/Gs : Desire for sour foods, craving for pickles
(steals money for the same). Bowel habits and
urine : Normal. Sweat from face, palms and soles
Physical appearance : the child was lean and
emaciated, wheatish complexioned.
27. Evaluation of symptoms
The case presents with strong
generals and characteristic
particulars and hence Kent’s
method of evaluation of
symptoms was followed in this
case. Synthesis Repertory (9.1)
version was used for
repertorization.
30. PRESCRIPTION
The basis of prescription :
The highest grade medicine in repertorization.
Recurrent tendency to various illness from change of
weather.
Unhealthy skin with painful eruptions.
The guiding factor being strong craving for sour food.
(SYNTHESIS REPERTORY : Generals, Food and
Drinks, sour foods, acids, desire : 3 remedies in 1st grade
: Cor-r., Hepar s., and Verat.).
Medicine selected : Hepar sulph.
31. Selection of medicine and
dosage
The case was prescribed Hepar sulph initially in 30
(few doses) potency followed by 200 (single dose)
interspersed with 2 doses of Sulphur 30.
Sulph 30 / 2 doses – justification –
to clear up the ground for proper action of selected
medicine, remove the miasmatic taint with H/o of
long contd. use of allopathic medications (in spite of
giving well selected medicine skin unable to regain
normal colour)
SYNTHESIS REPERTORY : Generalities, History,
medicine; of abuse of allopathic : Lach., Nux-v.,
Puls., Sulph., Thuja., and Zinc.)
34. OBSERVATION
These two cases of AD elaborated here opted for
homoeopathic treatment ( as 2nd choice) after relapse and
remission of skin lesions under prolonged modern
medicine treatment.
The assessment of outcome was based on :
Change in AD extension and severity,
Change in pruritus,
General and psychological wellbeing,
Improvement in quality of sleep.
Comparison of affected skin area between first and last
consultation showed significant improvement clinically.
35. Change of medicine…2nd prescription
‘In non-venereal chronic diseases those, therefore,
that arise from psora, we often require, in order to
effect a cure, to give several antipsoric remedies
in succession, every successive one being
homoeopathically chosen in consonance with the
group of symptoms remaining after the expiry of
the action of previous remedy (which may have
been employed in a single dose or in several
successive doses)’…..Aph. 171, Organon of
Medicine
36. Clinical studies on AD
1. Homoeopathic medical practice: long term results of a cohort study
with 3981 patients. (BMC Public Health | 2005 | Vol 5 | No 115 )
2. How healthy are chronically ill patients after 8 years of homoeopathic
treatment: results from a long observational study. (BMC Public Health |
2008 | Vol 8 | 413 )
3. Homoeopathy in pediatric atopic diseases: long term results in
children with AD. (Homeopathy | 2012 | Volume 101 | Issue 1 | Pages 13–20 )
4. Prospective observational study of 42 patients with AD treated with
homoeopathic medicines. (Homeopathy | 2012 | Volume 101 | Issue 1 |
Pages 21–27 )
Conclusion:
1. Disease severity and quality of life demonstrated marked and
sustained improvements following homoeopathic treatment.
2. Children showed a reduced tendency to maintain AD and develop
asthma and allergic rhinitis in adult age.
37. CURRENT RESEARCH ON AD
Conclusive research defining real efficacy and
best homoeopathic therapeutic strategies are still
insufficient.
Although the lack of sufficient research assessing
homoeopathic treatment of AD might lead to a
negative view of its possible effectiveness, the
fact that about half of patients with this disorder
resort to this alternative treatment is an indirect
indicator of their dissatisfaction with
conventional approaches.
38. CONCLUSION
These cases suggests that constitutional
homoeopathic medicines prescribed singly in
its potentised form definitely benefit the
patient.
Hence homoeopathic treatment could be
contemplated as an effective choice for patients
with AD.
But cases of AD require a long term follow-up
as the lesions have tendency to recur.