Schizophrenia is a severe brain disorder characterized by incorrect perceptions of reality and a combination of hallucinations, delusions, and disordered thinking. It typically develops in a person's 20s and can include symptoms like delusions, hallucinations, disordered thinking, abnormal motor behavior, and negative symptoms. While the exact causes are unknown, it is thought to involve genetic and environmental factors. Treatment involves lifelong medication and psychosocial therapy to manage symptoms.