Amazon S3 provides several security mechanisms to protect data including access control policies, encryption options, VPC endpoints, transfer acceleration, bucket policies, and key management. Case studies highlight how organizations like Capital One, the US Department of State, the FBI, BBC, Dow Jones, GE Healthcare, and the Royal Bank of Scotland have securely stored sensitive data on S3 by implementing security measures like encryption, access control, and logging. While S3 offers secure storage, it is important for users to also implement additional security best practices to fully protect their data.