Role of fertility clinics
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www.kiranivfgenetic.com Dr.Samit Sekhar : The Birth of a child brings in cheers and attaining parenthood is the dream of every couple as it is an eternally rewarding experience.
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Endocrine Therapy
Endocrine therapy is the cornerstone of treatment for HR+ breast cancer in postmenopausal women. The primary goal is to reduce the levels of estrogen or block its effects on cancer cells. Commonly used agents include:
Selective Estrogen Receptor Modulators (SERMs): Tamoxifen is a SERM that binds to estrogen receptors, blocking estrogen from stimulating breast cancer cells. It is effective but may have side effects such as increased risk of endometrial cancer and thromboembolic events.
Aromatase Inhibitors (AIs): These drugs, including anastrozole, letrozole, and exemestane, lower estrogen levels by inhibiting the aromatase enzyme, which converts androgens to estrogen in peripheral tissues. AIs are generally preferred in postmenopausal women due to their efficacy and safety profile compared to tamoxifen.
Selective Estrogen Receptor Downregulators (SERDs): Fulvestrant is a SERD that degrades estrogen receptors and is used in cases where resistance to other endocrine therapies develops.
Combination Therapies
Combining endocrine therapy with other treatments enhances efficacy. Examples include:
Endocrine Therapy with CDK4/6 Inhibitors: Palbociclib, ribociclib, and abemaciclib are CDK4/6 inhibitors that, when combined with endocrine therapy, significantly improve progression-free survival in advanced HR+ breast cancer.
Endocrine Therapy with mTOR Inhibitors: Everolimus, an mTOR inhibitor, can be added to endocrine therapy for patients who have developed resistance to aromatase inhibitors.
Chemotherapy
Chemotherapy is generally reserved for patients with high-risk features, such as large tumor size, high-grade histology, or extensive lymph node involvement. Regimens often include anthracyclines and taxanes.
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- 1. ROLE OF FERTILITY CLINICS IN SURROGACY TREATMENT(KIC) www.kiranivfgenetic.com
- 2. BIRTH OF CHILD The Birth of a child brings in cheers and attaining parenthood is the dream of every couple as it is an eternally rewarding experience. The medical science has grown in such huge proportion over the years that infertility treatment has moved forward rapidly. Some forms of infertility that were considered as untreatable in the past have now simple and successful solutions in this age of medical technology www.kiranivfgenetic.com
- 3. ROLE OF FERTILITY CLINICS The role played by fertility clinics and centers in India is commendable as these centers are helping couples in fulfilling their dreams of parenthood. www.kiranivfgenetic.com
- 4. FERTILITY CLINICS The establishment of fertility clinics or surrogacy centers has led to an increase in huge number of tourists coming to India as patients and their relatives who come for surrogacy/IVF is contributing to the economy by helping tourism industry directly and indirectly. The fertility industry in India has grown rapidly due to these fertility centers with more and more couples preferring surrogacy. www.kiranivfgenetic.com
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