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15TH WORLD CONFERENCE ON TOBACCO OR HEALTH
SINGAPORE
RESULTS OF A PILOT RANDOMIZED CONTROLLED TRIAL
OF SMS TURKEY, A TEXT MESSAGING-BASED SMOKING
CESSATION PROGRAM
MARCH 21, 2012 1:45 – 3:15 PM
ABSTRACT #OP-136
Michele Ybarra MPH PhD 1
Tulay Bagci Bosi PhD 2
Tonya Prescott BA 1
Josephine Korchmaros PhD 1
Jodi S Holtrop PhD 3
A.K. Salih Emri MD 2
1 Center for Innovative Public Health Research
2 Hacettepe University
3 Michigan State University
* Thank you for your interest in this
presentation. Please note that analyses
included herein are preliminary. More
recent, finalized analyses may be available
by contacting CiPHR for further
information.
ACKNOWLEDGEMENTS
Funding: The project described was supported by
Award Number R01TW007918 from the Fogarty
International Center. The content is solely the
responsibility of the authors and does not necessarily
represent the official views of the Fogerty
International Center or the National Institutes of
Health.
Declaration of Interest: The authors have no
competing interests to declare.
STUDY MOTIVATION
 44% of men and 12% of women smoke daily in
Turkey. (MoH Turkey, 2010)
 Over half of smokers report a desire to quit and
45% have made a quit attempt in the past year.
(MoH Turkey, 2010)
 Few are linked into cessation services however,
reducing the likelihood of their cessation success
(Akala & El-Saharty, 2006).
 Cell phones are 3.8 times more common than
landline phones (CIA World Factbook, 2011). We
posit text messaging can be used to deliver
smoking cessation programs in Turkey.
SMS TURKEY (CEBINZ BIRYAKIN DIYOR):
NUMBER OF MESSAGES
Pre-Quit (Day 1 – 13): 3 messages/day
Day before quit day (Day 14): 5 messages
Quit day and Day 2 post-quit: 8 messages/day
(both Early quit and relapse)
Day 3 – Day 4 post-quit: 6 messages
Day 5 post quit: 5 messages
Day 6 post-quit: 4 messages
Day 7 post-quit: 3 messages
(both Late quit and encouragement)
Day 8 – Day 21 post-quit: 2 messages/day
Day 22 – Day 28 post-quit: 1 message/day
SMS TURKEY (CEBINZ BIRYAKIN DIYOR):
MESSAGE TYPES
Preparation: When and why do you smoke? Start a
smoking diary to find out. Keep track of when you
smoke each cigarette, what you're doing (the activity),
how you're
Benefits of Quitting: Remember… former smokers
live longer than people who keep smoking. Fight the
urge to smoke today for better health tomorrow.
Encouragement: Have you been rewarding yourself
everyday that you are not smoking? What are you
going to do special for your self today for not smoking
SMS TURKEY (CEBINZ BIRYAKIN DIYOR):
MESSAGE TYPES
Pharmacotherapy: Put your reasons for quitting on
the fridge, or somewhere else where you will see
them. Talk to your doctor about pharmacotherapy, or
buy some nicotine gum at the store.
Coping strategies: Here are some coping strategies.
Practice the 4 D's as you work on cutting down:
Delay, Distract, Deep breathe, and Drink water.
(Dealing with) Discomfort: Many smokers do gain
some weight when they quit but it's because they eat
to compensate for not smoking. A healthy diet and
exercise can keep the weight off.
SMS TURKEY (CEBINZ BIRYAKIN DIYOR):
RCT METHODOLOGY
Eligibility criteria:
 18 years of age or older
 Owning a mobile phone and having used text
messaging in the past year
 Smoking daily
 Seriously thinking about quitting in the next 15 days
 Living in Ankara
 Not having a chronic disease
SMS TURKEY (CEBINZ BIRYAKIN DIYOR):
CONSORT TABLE
asdfa
sdf
SMS TURKEY (CEBINZ BIRYAKIN DIYOR):
SAMPLE CHARACTERISTICS (N=151*)
Personal characteristics Control
(n=75)
Intervention
(n=76)
P-
value
Demographic characteristics
Age (Range: 19-62) 35.6 (10.3) 36.1 (9.5) 0.76
Female 32.0% (24) 46.1% (35) 0.08
Lower income (<2000 ytl / mo) 49.3% (37) 30.3% (23) 0.02
Married 65.3% (49) 55.3% (42) 0.21
HH education or lower 50.7% (38) 36.8% (28) 0.09
Smoking characteristics
Average number of cigarettes
smoked per day (Range: 7-40) 20.4 (9.2) 18.7 (7.2) 0.21
Age at first cigarette (Range: 6-29) 17.1 (3.6) 17.5 (3.7) 0.48
Fagerström score (Range: 0-10) 4.9 (2.5) 4.8 (2.3) 0.79
*The submitted abstract included 134 participants. Results reported here include the full sample (n=151)
PRIMARY OUTCOME: CO-VERIFIED
CONTINUOUS ABSTINENCE AT 12 WEEKS
15%
5%
24%
11%
0%
5%
10%
15%
20%
25%
30%
35%
Among respondents at 12-
weeks
ITT (non-respondents are
smoking)
Control
Intervention
aRR = 2.0; 95% CI: 0.42, 9.9
aRR = 2.3, 95% CI: 0.57, 9.0
n=34
n=27
n=75
n=76
Relative Risk adjusted for: biological sex, income, education, smoking triggers, appraisal of good things about
smoking, appraisal of good things about quitting; and social support from family, friends, and a special person
12-WEEK CO-VERIFIED QUIT RATES BY
BIOLOGICAL SEX (ITT ANALYSES)
8%
0%
7%
14%
0%
2%
4%
6%
8%
10%
12%
14%
16%
Males Females (p=0.054)
Control
Intervention
n=51
n=41
n=24
n=35
12-WEEK CO-VERIFIED QUIT RATES BY
SMOKING INTENSITY (ITT ANALYSES)
9%
0%
7%
17%
0%
2%
4%
6%
8%
10%
12%
14%
16%
18%
Heavy smokers (20+
cigarettes/day)
Light (<20 ciagrettes/day)
p=0.03
Control
Intervention
n=46 n=46 n=29
n=30
SMS TURKEY (CEBINZ BIRYAKIN DIYOR):
CONCLUSION
Results provide optimism for future research on SMS
Turkey and other text messaging-based smoking
cessation programs in Turkey.
The SMS Turkey program seems to be especially
helpful for females and light smokers.
Based upon these findings, the next step should be a
sufficiently powered randomized controlled trial to
examine the efficacy of SMS Turkey at the national
level.

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Results of a pilot randomized controlled trial of SMS Turkey, a text messaging-based smoking cessation program

  • 1. 15TH WORLD CONFERENCE ON TOBACCO OR HEALTH SINGAPORE RESULTS OF A PILOT RANDOMIZED CONTROLLED TRIAL OF SMS TURKEY, A TEXT MESSAGING-BASED SMOKING CESSATION PROGRAM MARCH 21, 2012 1:45 – 3:15 PM ABSTRACT #OP-136 Michele Ybarra MPH PhD 1 Tulay Bagci Bosi PhD 2 Tonya Prescott BA 1 Josephine Korchmaros PhD 1 Jodi S Holtrop PhD 3 A.K. Salih Emri MD 2 1 Center for Innovative Public Health Research 2 Hacettepe University 3 Michigan State University * Thank you for your interest in this presentation. Please note that analyses included herein are preliminary. More recent, finalized analyses may be available by contacting CiPHR for further information.
  • 2. ACKNOWLEDGEMENTS Funding: The project described was supported by Award Number R01TW007918 from the Fogarty International Center. The content is solely the responsibility of the authors and does not necessarily represent the official views of the Fogerty International Center or the National Institutes of Health. Declaration of Interest: The authors have no competing interests to declare.
  • 3. STUDY MOTIVATION  44% of men and 12% of women smoke daily in Turkey. (MoH Turkey, 2010)  Over half of smokers report a desire to quit and 45% have made a quit attempt in the past year. (MoH Turkey, 2010)  Few are linked into cessation services however, reducing the likelihood of their cessation success (Akala & El-Saharty, 2006).  Cell phones are 3.8 times more common than landline phones (CIA World Factbook, 2011). We posit text messaging can be used to deliver smoking cessation programs in Turkey.
  • 4. SMS TURKEY (CEBINZ BIRYAKIN DIYOR): NUMBER OF MESSAGES Pre-Quit (Day 1 – 13): 3 messages/day Day before quit day (Day 14): 5 messages Quit day and Day 2 post-quit: 8 messages/day (both Early quit and relapse) Day 3 – Day 4 post-quit: 6 messages Day 5 post quit: 5 messages Day 6 post-quit: 4 messages Day 7 post-quit: 3 messages (both Late quit and encouragement) Day 8 – Day 21 post-quit: 2 messages/day Day 22 – Day 28 post-quit: 1 message/day
  • 5. SMS TURKEY (CEBINZ BIRYAKIN DIYOR): MESSAGE TYPES Preparation: When and why do you smoke? Start a smoking diary to find out. Keep track of when you smoke each cigarette, what you're doing (the activity), how you're Benefits of Quitting: Remember… former smokers live longer than people who keep smoking. Fight the urge to smoke today for better health tomorrow. Encouragement: Have you been rewarding yourself everyday that you are not smoking? What are you going to do special for your self today for not smoking
  • 6. SMS TURKEY (CEBINZ BIRYAKIN DIYOR): MESSAGE TYPES Pharmacotherapy: Put your reasons for quitting on the fridge, or somewhere else where you will see them. Talk to your doctor about pharmacotherapy, or buy some nicotine gum at the store. Coping strategies: Here are some coping strategies. Practice the 4 D's as you work on cutting down: Delay, Distract, Deep breathe, and Drink water. (Dealing with) Discomfort: Many smokers do gain some weight when they quit but it's because they eat to compensate for not smoking. A healthy diet and exercise can keep the weight off.
  • 7. SMS TURKEY (CEBINZ BIRYAKIN DIYOR): RCT METHODOLOGY Eligibility criteria:  18 years of age or older  Owning a mobile phone and having used text messaging in the past year  Smoking daily  Seriously thinking about quitting in the next 15 days  Living in Ankara  Not having a chronic disease
  • 8. SMS TURKEY (CEBINZ BIRYAKIN DIYOR): CONSORT TABLE asdfa sdf
  • 9. SMS TURKEY (CEBINZ BIRYAKIN DIYOR): SAMPLE CHARACTERISTICS (N=151*) Personal characteristics Control (n=75) Intervention (n=76) P- value Demographic characteristics Age (Range: 19-62) 35.6 (10.3) 36.1 (9.5) 0.76 Female 32.0% (24) 46.1% (35) 0.08 Lower income (<2000 ytl / mo) 49.3% (37) 30.3% (23) 0.02 Married 65.3% (49) 55.3% (42) 0.21 HH education or lower 50.7% (38) 36.8% (28) 0.09 Smoking characteristics Average number of cigarettes smoked per day (Range: 7-40) 20.4 (9.2) 18.7 (7.2) 0.21 Age at first cigarette (Range: 6-29) 17.1 (3.6) 17.5 (3.7) 0.48 Fagerström score (Range: 0-10) 4.9 (2.5) 4.8 (2.3) 0.79 *The submitted abstract included 134 participants. Results reported here include the full sample (n=151)
  • 10. PRIMARY OUTCOME: CO-VERIFIED CONTINUOUS ABSTINENCE AT 12 WEEKS 15% 5% 24% 11% 0% 5% 10% 15% 20% 25% 30% 35% Among respondents at 12- weeks ITT (non-respondents are smoking) Control Intervention aRR = 2.0; 95% CI: 0.42, 9.9 aRR = 2.3, 95% CI: 0.57, 9.0 n=34 n=27 n=75 n=76 Relative Risk adjusted for: biological sex, income, education, smoking triggers, appraisal of good things about smoking, appraisal of good things about quitting; and social support from family, friends, and a special person
  • 11. 12-WEEK CO-VERIFIED QUIT RATES BY BIOLOGICAL SEX (ITT ANALYSES) 8% 0% 7% 14% 0% 2% 4% 6% 8% 10% 12% 14% 16% Males Females (p=0.054) Control Intervention n=51 n=41 n=24 n=35
  • 12. 12-WEEK CO-VERIFIED QUIT RATES BY SMOKING INTENSITY (ITT ANALYSES) 9% 0% 7% 17% 0% 2% 4% 6% 8% 10% 12% 14% 16% 18% Heavy smokers (20+ cigarettes/day) Light (<20 ciagrettes/day) p=0.03 Control Intervention n=46 n=46 n=29 n=30
  • 13. SMS TURKEY (CEBINZ BIRYAKIN DIYOR): CONCLUSION Results provide optimism for future research on SMS Turkey and other text messaging-based smoking cessation programs in Turkey. The SMS Turkey program seems to be especially helpful for females and light smokers. Based upon these findings, the next step should be a sufficiently powered randomized controlled trial to examine the efficacy of SMS Turkey at the national level.

Editor's Notes

  1. Compared to the United States where 23% of men and 18% of women are current smokers (Pleis JR, Ward BW, Lucas JW. Summary health statistics for U.S. adults: National Health Interview Survey, 2009. Vital Health Stat 10. 2010(249):1-207)Text messaging may be a way to increase the availability of cessation services because it is both scalable and cost effective. 
  2. This 6-week program begins two weeks prior to one’s quit day and continues through 4-weeks post-quit.  Daily text messaging content is based upon cognitive behavioral therapy (e.g., self-efficacy, replacement of old behaviors with new, relapse prevention).
  3. Similar in terms of smoking characteristicsDifferent in terms of demographic characteristics: intervention was less likely to be lower income and lower education; and more likely to be female