The document discusses using a reliable messaging pattern called the message mule pattern with VM persisted queues to ensure zero message loss. It proposes storing messages in VM queues before delivering them to transactions or business flows. This allows messages to remain in the queue until accepted by the next system, ensuring messages are not lost due to trivial network issues. The solution can persist queues in Mule CloudHub and shows how to configure VM queues in Anypoint Studio using global connectors and inbound/outbound endpoints.