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RED-S Syndrome in Men & Women
PRESENTED BY: HANNA PANCH
Evolution of RED-S Syndrome
Female Athlete Triad
• Female Athlete Triad
• Defined as female athletes who
have had the following three
components:
1. Eating disorders
2. Menstrual Abnormalities
3. Low bone mineral density
Evolution of RED-S Syndrome
Female Athlete Triad Changes
• Most important change occurred in 2007
by the American College of Sports
Medicine (ACSM):
• Term was redefined to having components
of energy availability (EA), menstrual
function, and bone health
• Marked EA as the main cause for the
Female Athlete Triad
EA = (Dietary Intake (EI) – Energy Cost of
Exercise) / Fat- Free Mass (FFM)
Healthy Adults: value of 45/kcal/kg FFM/day =
energy balance
Energy Availability
• Decrease seen in weight
sensitive sports
• This can be caused by
1. Specific performance
roles
2. Body appearance
3. Competing weight class
requirement
Evolution of RED-S Syndrome
Female Athlete Triad to RED-S
• The International Olympic Committee
(IOC) created the term RED-S
• Energy Deficiency is a problem for both males
and females
• Expansion on the components that were
originally in the ‘triad’
• Affects the physically active population, not just
athletes
Consequences associated with RED-S
• Low estrogen
• Risk of stress fractures
• Nutrient Deficiencies
• Decreased Endurance
• Decreased Coordination
• Decrease in Metabolic Metabolism
• Decrease in production of growth hormone
• Decrease in Muscle Strength
• Fertility issues (long-term)
Consequences of RED-S Syndrome
• Psychological Component- Double
Arrow:
• Energy deficiency can cause
psychological issues
• psychological issues can cause
energy deficiency
RED-S Syndrome in Males
• Low EA in males:
• Can cause hormonal dysfunction
• Disruption in GnRH and LH pulsatality which
decreases testosterone
• Reproductive Dysfunction in endurance athletes
• Lack of education in health care professionals in
identifying males with RED-S
• Hard to identify male athletes at risk for RED-S
RED-S Syndrome in Males
Low EA in Elite Male Athletes
• Commonness in Disorderly
Eating in Males:
• Cycling: 50%
• Weight Class events: 18%
• Gravitational sports: 24%
• Disorderly eating related to
low bone mass
Previous Research on Olympic Athletes
Exercise Time and Load
• Study done in a University Hospital on 223 participants (125 Males; 98 females) who were
all past participants of the Olympic games of 2002 and 2004
• This study looked at the weight control strategies used by the Olympic athletes who
strived for leanness in order to gain a performance advantage
• Results: Represented in Table 3
• Exercise Time:
• Athletes who participated in leanness-stressed disciplines was higher than non-
leanness stressed disciplines
• Negative correlation for entire population between training time and BMI (r =
-0.23; P < 0.01)
• Training load >10 was described more from athletes in leanness-stressed disciplines
(Hagmar. Hirschberg, Berglund,
Berglund, (2008)
Previous Research on Olympic Athletes
Illness & Injuries
• Results: Represented in Table 3
• Illness:
• Athletes in leanness-stressed disciplines exhibited higher
reported illnesses than athletes in non-leanness stressed
disciplines
• Only statistical significance in males who practiced
leanness-stressed disciplines
• Injury:
• Athletes in leanness-stressed disciplines exhibited higher
reported injuries than athletes in non-leanness stressed
disciplines
• Statistical difference in males only who practiced
leanness-stressed disciplines. (higher amount of reports
of injury 3 months prior to Games)
IOC’s RED-S Risk Assessment Model for Sport Participation
IOC’S RED-S Sport Decision- Based Return-to-Play Model
IOC’s RED-S Return-to-Play Model
Future Research Needs for
RED-S
• Finding effective methods to identify athletes at risk for RED-S.
• Creating scientifically validated prevention interventions for RED-S.
• Continued research on how RED-S affects male athletes, different ethnicities, and
Paralympic athletes
• Research on RED-S in how it varies between different sports.
• Guidelines for the treatment for RED-S in athletes and ‘return to play.’
Questions?

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RED-S Syndrome in Athletes

  • 1. RED-S Syndrome in Men & Women PRESENTED BY: HANNA PANCH
  • 2. Evolution of RED-S Syndrome Female Athlete Triad • Female Athlete Triad • Defined as female athletes who have had the following three components: 1. Eating disorders 2. Menstrual Abnormalities 3. Low bone mineral density
  • 3. Evolution of RED-S Syndrome Female Athlete Triad Changes • Most important change occurred in 2007 by the American College of Sports Medicine (ACSM): • Term was redefined to having components of energy availability (EA), menstrual function, and bone health • Marked EA as the main cause for the Female Athlete Triad EA = (Dietary Intake (EI) – Energy Cost of Exercise) / Fat- Free Mass (FFM) Healthy Adults: value of 45/kcal/kg FFM/day = energy balance
  • 4. Energy Availability • Decrease seen in weight sensitive sports • This can be caused by 1. Specific performance roles 2. Body appearance 3. Competing weight class requirement
  • 5. Evolution of RED-S Syndrome Female Athlete Triad to RED-S • The International Olympic Committee (IOC) created the term RED-S • Energy Deficiency is a problem for both males and females • Expansion on the components that were originally in the ‘triad’ • Affects the physically active population, not just athletes
  • 6. Consequences associated with RED-S • Low estrogen • Risk of stress fractures • Nutrient Deficiencies • Decreased Endurance • Decreased Coordination • Decrease in Metabolic Metabolism • Decrease in production of growth hormone • Decrease in Muscle Strength • Fertility issues (long-term)
  • 7. Consequences of RED-S Syndrome • Psychological Component- Double Arrow: • Energy deficiency can cause psychological issues • psychological issues can cause energy deficiency
  • 8. RED-S Syndrome in Males • Low EA in males: • Can cause hormonal dysfunction • Disruption in GnRH and LH pulsatality which decreases testosterone • Reproductive Dysfunction in endurance athletes • Lack of education in health care professionals in identifying males with RED-S • Hard to identify male athletes at risk for RED-S
  • 9. RED-S Syndrome in Males Low EA in Elite Male Athletes • Commonness in Disorderly Eating in Males: • Cycling: 50% • Weight Class events: 18% • Gravitational sports: 24% • Disorderly eating related to low bone mass
  • 10. Previous Research on Olympic Athletes Exercise Time and Load • Study done in a University Hospital on 223 participants (125 Males; 98 females) who were all past participants of the Olympic games of 2002 and 2004 • This study looked at the weight control strategies used by the Olympic athletes who strived for leanness in order to gain a performance advantage • Results: Represented in Table 3 • Exercise Time: • Athletes who participated in leanness-stressed disciplines was higher than non- leanness stressed disciplines • Negative correlation for entire population between training time and BMI (r = -0.23; P < 0.01) • Training load >10 was described more from athletes in leanness-stressed disciplines (Hagmar. Hirschberg, Berglund, Berglund, (2008)
  • 11. Previous Research on Olympic Athletes Illness & Injuries • Results: Represented in Table 3 • Illness: • Athletes in leanness-stressed disciplines exhibited higher reported illnesses than athletes in non-leanness stressed disciplines • Only statistical significance in males who practiced leanness-stressed disciplines • Injury: • Athletes in leanness-stressed disciplines exhibited higher reported injuries than athletes in non-leanness stressed disciplines • Statistical difference in males only who practiced leanness-stressed disciplines. (higher amount of reports of injury 3 months prior to Games)
  • 12. IOC’s RED-S Risk Assessment Model for Sport Participation
  • 13. IOC’S RED-S Sport Decision- Based Return-to-Play Model
  • 15. Future Research Needs for RED-S • Finding effective methods to identify athletes at risk for RED-S. • Creating scientifically validated prevention interventions for RED-S. • Continued research on how RED-S affects male athletes, different ethnicities, and Paralympic athletes • Research on RED-S in how it varies between different sports. • Guidelines for the treatment for RED-S in athletes and ‘return to play.’

Editor's Notes

  1. Mountjoy M. [Aspetar]. (2015, March 30). Relative energy deficiency in sports (RED-S) by Dr Margo Mountjoy [Video file]. https://www.youtube.com/watch?v=GlV5mVOGo1c
  2. (Mountjoy, 2015) Marcason, W. (2016). Female athlete triad or relative energy deficiency in sports (RED-S): is there a difference?. Journal of the Academy of Nutrition and Dietetics, 116(4), 744.
  3. (Marcason, 2016)
  4. (Marcason, 2016)
  5. (Marcason, 2016) (Mountjoy, 2015)
  6. (Mountjoy, 2015)
  7. McCallum Place, Kerr, C., Tierney, A. S., Brauer, A., Leslie, J., Walker-Leard, S. (2018, March 15). Male runners and eating disorders. https://www.mccallumplace.com/about/blog/male-runners-and-eating-disorders/ (Mountjoy, 2014)
  8. Mountjoy, M., Sundgot-Borgen, J. K., Burke, L. M., Ackerman, K. E., Blauwet, C., Constantini, N., ... & Sherman, R. T. (2018). IOC consensus statement on relative energy deficiency in sport (RED-S): 2018 update. British Journal of Sports Medicine. Mountjoy, M., Sundgot-Borgen, J., Burke, L., Carter, S., Constantini, N., Lebrun, C., ... & Ljungqvist, A. (2014). The IOC consensus statement: beyond the female athlete triad—Relative Energy Deficiency in Sport (RED-S). Br J Sports Med, 48(7), 491-497.
  9. Hagmar, M., Hirschberg, A. L., Berglund, L., & Berglund, B. (2008). Special attention to the weight-control strategies employed by Olympic athletes striving for leanness is required. Clinical Journal of Sport Medicine, 18(1), 5-9.
  10. (Hagmar, Hirschberg, Berglung, L., Berglund B., 2008)
  11. (Mountjoy, 2014)
  12. (Mountjoy, 2014)
  13. (Mountjoy, 2014)
  14. (Mountjoy et al., 2018)