Using emerging technology and innovation to create sustainable impact in the areas of healthcare, robotics, and AI

1. March 2021
BUILDING NEW
ECOSYSTEMS
@ the intersection of
healthcare, robotics and AI
New Ideas, New Opportunities, New Directions

2. IT’S NOT INNOVATION
It’s future-focused collaborative
business development.
We surface unique and unexpected
business opportunities, short-term and
long-term, across a broadly defined
health care and wellness domain.
We then identify and connect potential
partners who can work together to create
new value and bring combined offerings
to the marketplaces.
On the following pages, we describe our
approach, methods, and strategies.

3. NON-OBVIOUS TIMELINES
RADICAL
PRESENT
Small-scale short-term
opportunities that lay the
groundwork for long-term
growth outside of current
business areas.
Many innovation programs are
excellent at projecting a medium-term
future from current business activities.
This is useful but misses less-obvious
opportunities in the extreme short-
and long-term.
CHALLENGE
Extended (XT) teams made up of
diverse participants from a wide
range of fields and global ecosystems
can explore wider, deeper, and faster
to find unexpected opportunities.
SOLUTION
NEXT 20 YEARS
NEXT 10 YEARS
NEXT 3 YEARS
NEXT YEAR
NEXT 3 MONTHS
NEXT 3 WEEKS
NEXT WEEK
MEDIUM
FUTURES
Medium-term
extrapolations of obvious
trends in currently-served
business areas and
ecosystems.
RADICAL
FUTURES
Trends from outside
currently-served
ecosystems and/or
accelerated change.

4. THE PRICE OF SUCCESS
Many successful companies,
expanding organically and through
periodic acquisitions, are still missing
important opportunities due to their
historical pattern of growth.
Engage an external group to
provide a fresh, unexpected, and
future-oriented perspective to
generate new insights on
near-term and long-term
opportunities.
CHALLENGE
SOLUTION
Unexplored Territories
Fast-moving trends from outside existing
business ecosystems often create huge
new areas of opportunity that require new
thinking, new relationships, and new
investments.
Gaps in Customer / Capabilities Matrix
There are often hidden opportunities at points
where market and technology platforms
intersect that are under-served because of
existing relationships, organizational silos, and
shared orthodoxies.
COMMON PAIN POINTS

5. INNOVATION ECOSYSTEM
Many companies with highly effective
internal innovation teams still have
trouble expanding their business
ecosystems beyond the “usual
suspects”, e.g. research and academic
partners.
We can use a “community
intelligence” approach to
systematically engage outside
participants using a broad range
of virtual collaborative interactions.
CHALLENGE
SOLUTION
Hardware &
Software
Design
Process
and System
Design
But healthcare is a
complex “system of
systems” requiring
multidimensional
collaboration. Documentation
and Training
Testing and
Monitoring
Regulation
and
Compliance
Basic
Research
Healthcare
Delivery and
Funding

6. ALREADY ON THE MAP
Some trends that are
already visible …
RADICALLY DISTRIBUTED 🡲
mobile micro-miniaturization of diagnostics and
treatment … decline of the hospital and laboratory.
• Distributed diagnosis, delivery and monitoring of
personalized treatments
• Integrated AI-powered analysis across multiple
specialties, accessing combined global diagnostic
databases
• Consumer-friendly and IoT-connected
• Targets:
Chronic conditions
Aging-in-place and home care
Urgent care facilities, nursing homes
Telehealth and self-care, personalized medicine
Wellness, non-invasive and non-pharma treatments
RADICALLY LOWER COST 🡲
equipment designs and remote manufacturing facilities.
• Design in global teams with diverse perspectives
• Streamlined processes and systems
• Global documentation and training platforms
• Targets:
Developing nations or regions
Global distribution networks
Large retail clinic networks
RADICALLY FASTER 🡲
on-demand customization of production lines and
equipment
• VR + AI + agile design and engineering techniques
• Rapid reprogramming of additive and robotic manufacturing
• VR and virtual training, process re-design
• Targets:
Time-critical public health initiatives
Pandemic testing, vaccine development
Multiple partners beyond traditional hospital and
healthcare systems

7. EXTENDED TEAMS (XT DEVELOPMENT)
The XT concept engages the most relevant outside communities at each step in the process, using a
highly structured and efficient interaction design to maximize results and reduce costs.
OPPORTUNITY CONCEPT PLAN PROJECT PRODUCT PLATFORM
CHALLENGE
dedicated team members
users, customers, partners, suppliers, industry experts, influencers, policy makers …
GOALS Interactions Inputs > Activities > Outputs Phase OUTCOMES
Work with XT
members to identify
shared opportunities
and incorporate
ecosystem concepts
into their future
strategies
1 1-on-1 phone
industry
experience
review challenge, capture
opportunity areas
~10 areas challenge
Consensus
on shared
opportunity
map; initial
idea map(s)
2 online survey ~10 areas
review, add areas + initial
ideas
~20 areas, ~10
ideas
opportunity
3
virtual meeting
session 1
map based on
~20 areas
review, sign off on map,
add ideas
approved
opportunity map
ideas
4
virtual session
2
map ~10 ideas brainstorm additional ideas idea map(s) ideas
fra
me
list
en
collabor
ate
activ
ate
ACTIVITY DESIGN EXAMPLE (PARTIAL)
INTERACTION FACILITATION MODEL
IDEAS

8. EXAMPLE ACTIVITIES
2. Mapping
Workshops
Identifying new opportunities
adjacent to existing capabilities and
customers.
3. Futures
Thinking
Projecting unique areas of value
based on future trends in needs,
technologies and markets.
4. Long-Term
Program Design
Recommendations from the
Reciprocity partner network for
new programs and processes at to
enhance your long-term
organizational potential for
developing new businesses
1. Discovery
Facilitated
discussions of focus
and scope with
selected
stakeholders.

9. EXAMPLE DESCRIPTIONS
2. Mapping Workshops
3 to 6 virtual design workshops, internal + external
participants, structured and facilitated by Reciprocity; w/
interviews, surveys, analysis, visualization.
Ecosystem Mapping
Identify where successful new ideas in your current organization /
ecosystem, and map the typical pathways and obstacles as they
move between groups and departments in development.
Platform Mapping
Build a matrix of your capabilities and customers in the health
care domain, and identify gaps as well as areas of opportunity
which are extensions of existing strengths.
Construction Roadmap
Design a near-term plan for improving development pathways
and building and/or acquiring new platform extensions.
Under-
Leveraged Assets
Do you have IP or
expertise which is
underutilized and can be
applied to new areas of
opportunity?

10. EXAMPLE DESCRIPTIONS
3. Futures Thinking
Series of ideation workshops and research streams,
structured and staffed by Reciprocity with our partners and expert
network; w/ customer interviews, analysis, and visualizations.
Projections / Intersections
Extrapolate trends inside and outside of health-related issues;
identify critical intersections between trends and identify key
“rising challenges” for life science technologies.
Systems / Scenarios
Create a series of scenarios in which major systemic shifts (in
society + economy + technology) combine to reshape the health
care, wellness, and life sciences landscape.
Future Platforms
Describe (medium- and long-term) future additions to the your
current matrix of customer and capability platforms, including
suggestions for internal development, investments and acquisitions.
Benefits
Catch and ride big
trends + broad long-term
growth (20+ years) +
agility and foresight in
uncertain times

11. EXAMPLE DESCRIPTIONS
4. Long-Term Program Design
Surveys, interviews, and program planning work by
Reciprocity partners and network, leading to detailed
program design recommendations.
Ecosystem Management
Strategies for improving idea generation, idea-to-development
pathways, extended innovation teams, innovation at all steps
from challenge to market, next week to 20+ years.
IP & Knowledge Management
Strategies to systematically leverage research, ideation and
intellectually property development for market positioning,
development planning.
Investments & Acquisitions
Detailed roadmaps connecting opportunities (from platform
extensions to future scenarios) with potential partnerships,
investments and acquisitions.
Benefits
long-term process and
infrastructure readiness
+ you can own and
disseminate program
methodologies and
insights

12. RECIPROCITY TOOLKIT
The Reciprocity process integrates a
variety of tools for identifying areas of
opportunity at the intersection of
capabilities, objectives, and
applications, including:
• Intersections Map
• Objectives Map
• Iterative Roadmap
• Opportunity Scenarios
• Ecosystem Concepts

13. EXAMPLE INTERSECTIONS
Healthcare
& Wellness
AI
Robotics,
Automation
(ICT)
advanced
telehealth
personalized
medicine
home care /
point of care
solutions
population,
public &
community
health
AI
diagnosis
robotic
therapy
AI
EHR
AI interfaces
robotic
care assistance
remote
clinics
3D
printing at
POC
automated
testing &
manufacturing
robotic
surgery
rapid
prototyping &
customization
CAPABILITIES
APPLICATIONS
AI R&D
AI + 3D
printing

14. Healthcare
& Wellness
AI
Robotics,
Automation
(ICT)
advanced
telehealth
personalized
medicine
home care /
point of care
solutions
population,
public &
community
health
AI
diagnosis
AI R&D
robotic
therapy
AI
EHR
AI + 3D
printing
AI interfaces
robotic
care assistance
remote
clinics
3D
printing at
POC
automated
testing &
manufacturing
robotic
surgery
rapid
prototyping &
customization
EXAMPLE OBJECTIVES
New Models
for Affordable
Care
Pandemic
Solutions
Aging in Place
Distributed
Care

15. WORKING MAPS
We maintain “working maps” which are
updated as we explore the field and develop
relationships. Attached are PDF versions of
two examples of our current maps.
15
OBJECTIVES MAP
INTERSECTIONS
MAP

16. ITERATIVE ROADMAP
EXPLORATION
opportunity scenario
and ecosystem
concept
development
SHORT-TERM
DEVELOPMENT
“screwdriver”
products + services,
no FDA approval
MID-TERM
DEVELOPMENT
ground-up
product/service dev,
no FDA approval
LONG-TERM
DEVELOPMENT
ground-up dev
initiative, requires
FDA approval
We favor an iterative process which emphasizes agile
techniques (e.g. MVPs, codeless application development) in the
development of integrated product / service ecosystems, and
prioritizes early / easy wins in the first phases of the program.

17. ITERATIVE EXPLORATION
MAPPING
develop and iteratively refine a
series of maps (intersections +
objectives) to identify areas of
opportunity where strong
internal + RROI capabilities
coincide with strong market
potential + white space
SCENARIOS
Identify and research promising
opportunity scenarios and
“seed” solutions
BUILDING ECOSYSTEMS
confirm potential ecosystem partners and
develop collaborative relationships, leading
to a shared development agenda
SPIN OUT PROJECTS
Identify high-potential short-term projects
to engage with specific areas of
opportunity, sooner and at lower risk.
EXPLORATION
XT (extended team)
research and ideation
process with core
RROI and internal
team members
CONCEPTS
develop ecosystem concepts
and identify potential internal
roles plus appropriate
external partners including
RROI portfolio companies
and relationships
Exploration is both
a first step and
ongoing process.

18. ITERATIVE DEVELOPMENT TYPES
1. SHORT-TERM DEVELOPMENT
FOCUS: Look for “screwdriver projects” that only take hardware assembly or repurposing + software
integration to bring to market. FDA approvals not required.
POTENTIAL STRATEGY: Use JV with RROI partner and portfolio companies as an “agile”
development framework for a group of opportunities. Bring in Robotics Hub and IPS as partners.
Provide shared services (sales, marketing etc.) to all initiatives, thus lowering operating costs. A
quick way to launch, avoiding internal bottlenecks and leveraging an external ecosystem.
2. MID-TERM OPPORTUNITIES
FOCUS: Concepts that require ground-up product / service development in specific white spaces,
but FDA approval is not required.
POTENTIAL STRATEGY: Create a joint investment initiative to build a separate new or existing
startup for each opportunity.
3. LONG-TERM OPPORTUNITIES
FOCUS: Scenarios and concepts that require ground-up development plus FDA approval.
POTENTIAL STRATEGY: Same as mid-term opportunities i.e. creating a startup with joint funding.

19. DEEP SENSING
At appropriate points in the iterative process,
particularly in complex scenarios or where new product
adoption require large scale transitions involving
multiple, we can add an extra level of “deep sensing” to
improve outcomes.
We use a variety of tools, including ethnography, “community
intelligence” participatory development, and psycholinguistics.
For example, we can leverage our psycholinguistics team (including
data scientists, clinical psychologists, data analysts and behavioral
scientists) to do large-scale profiling of populations across various
demographics and disciplines based on their online presence,
leveraging AI-based large-data-set analysis.
The AI runs incognito, avoiding bias based on a predefined outcome,
delivering insights on critical relationship areas such as aptitude,
emotional range, values and needs, openness, conscientiousness,
extraversion and agreeableness.
FOCUS AREAS
Team Development
Client and Partner Identification
Audience Intelligence
Data Story Telling Visualization
Customer Journey Mapping
New Product / Process Adoption

20. EXAMPLE OPPORTUNITY SCENARIOS
On the following pages are
three example opportunity
scenarios we’ve been working
on, which illustrate the potential
to address strong areas of
opportunity with an ecosystem
approach.
Safe
Spaces
Distributed
+ Affordable
Long-Term
Telecare

21. SCENARIO #1: Safe Spaces
Office, schools, warehouses,
factories, all closed spaces at risk
of spreading infection …
How do we gather again in public
spaces safely, without public
health risks?
And how can AI and robotics help?

22. CONCEPT #1: Seed Solution
Combines Contact Tracing with Spatial
Intelligence to track infections
and exposures in public spaces, using just the
smartphones that employees carry at all times.
Exposure Notifications
Maps the floorplan and office layout. Employees receive alerts
if a co-worker in the same area tested positive.
Targeted Decontamination
Track alerts on which areas were exposed to infection to help
target policies and decontamination efforts.
Completely anonymous
Users need not divulge their identity to anyone. Tracks
devices, not users. No logins. No emails.

23. CONCEPT #2: Ecosystem Solutions
MARKET
• OFFICES
• FACTORIES
• WAREHOUSES
map spaces and
track people flow,
contract tracing
Saferle
Reciprocity portfolio
control disinfection
robots and track status
of spaces
e.g. TIMA robot
disinfector
byINFOCOM
Reciprocity portfolio
order food,
supplies, packages
integrate w/ facility
management features
e.g. Curant /
potential partner
end user apps
admin control
data tracking
spatial analysis
mobile robotics
consulting
deliver food,
supplies, packages
e.g. Macco
Reciprocity portfolio
TARGET CUSTOMER
• PROPERTY MANAGEMENT
• LARGE COMMERCIAL OWNERS
• FACILITY MANAGERS
robotic self-managed
parking with EV
charging and end-user
app
e.g. Stak
potential partner

24. SCENARIO #2: Long-Term Telecare
Many long-term conditions
require long-term treatments with
constant monitoring, consultation,
and adjustment of care plans.
Long-term hospitalization
doesn’t make sense, but managing
the process remotely is complex
and prone to failure.
How can we use AI, robotics,
and cloud technologies to help?

25. CONCEPT #1: Seed Solution
A digital therapeutics platform that enables spine
patients and their care team to communicate and
collaborate to increase adherence and positive
outcomes while decreasing healthcare costs.
• Care and Wellness Plans
• Treatment Spaces
• Clinical Collaboration
• Workout Routines and Exercises
• Video and Chat Telehealth
• Connect Biometric Devices
• Spine Wellness Coaches
• Family Member Access
• Tasks, Reminders, and Check-Ins
• Document and Imaging Manager
• Reports

26. CONCEPT #2: Ecosystem Solutions
MARKET & CUSTOMERS
• SPINE PATIENTS
• SPINAL CARE PRACTICES
• HEALTH MANAGEMENT SYSTEMS
interfaces with patients,
caregivers, care team,
integrates care plans,
data, devices
SPINEDTx
Reciprocity portfolio
rehabilitation robots
provide physical
assistance, therapy to
accelerate recovery
TBD
integrate with EHR,
imaging analysis, AI
diagnostics, and other
health provider
applications
TBD
end user app
care team app
telehealth functions
data tracking
wearable sensors
rehabilitation robotics
integration
wearable and
biometric devices
track musculoskeletal
system to detect any
issues with movement
and posture patterns.
TBD

27. CONCEPT #3: Replicate for Multiple Conditions
MARKET & CUSTOMERS
• OTHER LONG-TERM CARE PATIENTS
• CARE PRACTICES
• HEALTH MANAGEMENT SYSTEMS
interfaces with patients,
caregivers, care team,
integrates care plans,
data, devices
[DTx Platform]
Reciprocity portfolio
a variety of
robots and robotic
devices provide
physical assistance
and therapy, monitor
movement, dispense
medication, etc.
TBD
integrate with EHR,
imaging analysis, AI
diagnostics, and other
health provider
applications
TBD
end user app
care team app
telehealth functions
data tracking
wearable sensors
assistive robotics
integration
wearable and
biometric devices
track a wide range of
patient data relevant to
the long-term condition
and general health
TBD

28. SCENARIO #3: Distributed + Affordable
Technology has the potential to
make healthcare …
Radically more distributed …
so it is available anywhere in the world and
as close to the most convenient point of care
(home, school, work) as possible.
Radically more affordable ...
so it is available to all communities without
economic limitations.
These two goals are complementary and
synergistic. How can leverage robotics
and AI move them forward together?

29. Non-Invasive
Treatments
Emphasize solutions, from
wellness to home care to
DNA therapy, that don’t
require expensive surgical
treatments and hospital
stays.
ENABLING TECHNOLOGIES
Artificial
Intelligence
Shorten time to
diagnosis, reduce need for
expensive specialists,
speed up research and
personalization
Smart Clinics
Small distributed facilities
(street, village, retail,
school, work) that are
highly connected,
automated, and authorized
for a wide range of
healthcare scenarios.
Robotics /
Automation /
Reduce costs for staff
and monitoring, easier to
monitor by AI or
remotely.
Micro /
Miniaturization &
Simplification
More compact,
lower-cost, possible to
install in small clinics, in
the home, in mobile
devices.
Telehealth,
Mobile, IoT
Connected solutions that
reduce travel time and the
need for centralized
facilities, and enable home
care and aging-in-place.
These technologies are
also complementary and
synergistic.
How can we maximize the
synergies as they are
being developed?

30. DATA POINTS
A lot of work is
being done on gene
therapy related to aging,
which may seem like a
luxury. But it can reduce
healthcare costs drastically
by avoiding care
interventions and
hospitalizations related to
chronic conditions.
A few data
points from
recent news.
Reductions in size
and cost of medical
equipment open up many
possibilities for more
distributed and affordable
care. There are recent
developments… here’s a
portable X-ray device.
The value of
technology in addressing
home care and
aging-in-place is huge,
particularly in a
locked-down world. An
article on technologies that
make remote caregiving
more effective.

31. Virtual Incubators
with Extended
Teams
CONCEPT #1: Research Ecosystem
“Coalition for
Affordable &
Distributed
Healthcare” Spinouts and
Startups,
Ecosystem
Development
Consortium of
Partners
(researchers,
developers, providers,
consumers)
Shared Research
Agenda and
Scenario
Development
Integration
Prototypes & Pilot
Projects

32. CONCEPT #2: Last Mile Ecosystem
Technical & Medical Expertise
Connectivity & Infrastructure
Maintenance and Support
All of these solutions,
however, have a common
weakness …
BARRIERS
… the “last mile” from
centralized sources of
expertise and technology
support to the distributed
point of care. This is a
major challenge,
especially as solutions
become more
sophisticated and
integrated.
Home
Local
Clinic
Office
School
Nursing
Home

33. CONCEPT #2: Integrated Platform
Social
connectivity
If we partner to
develop an
integrated platform,
we can “own” the
last mile …
BARRIERS
Family
caregiving
Non-medical
interventions and
monitoring
(diet, fitness)
Medication
dispensing and
monitoring
Medical diagnosis
and consultation
Specialized
testing and
prescriptions
Specialized
non-surgical
interventions
Personalized
medicine
Emergency
medicine
… and broker a
wide range of
solutions to
distributed points
of care.
Home
Local
Clinic
Office
School
Nursing
Home

34. CONCEPT #2: Service & Support
A central component
might be a sophisticated
“service and support”
stack with proprietary
integration and
management software.
SERVICE & SUPPORT STACK
Patient support & training
Caregiver support & training
Clinic staff support & training
Software installation and testing
Hardware installation and testing
Performance and outcomes monitoring
Solution integration software development
Patient, provider and services management
Home
Local
Clinic
Office
School

35. NEXT STEPS
Here’s a possible on-ramp to the
iterative roadmap:
EXPLORATION
opportunity scenario
and ecosystem
concept
development
1. Discuss goals and framework for
collaboration.
2. Share current interests, projects.
3. Decide on scope of exploration phase:
a) Time
b) Schedule
c) Budget
4. Agree on criteria for selecting opportunities
and concepts for further development.