Determination of DNA Methylation Using Electrochemiluminescenc.docx
Raja Sivanantham Ulster Uni Coleraine B Sc Research Slides
1. Do sulphur-containing compounds interfere with beta-cell glucose metabolising enzyme function? M. S. S. Raja Sivanantham (B00535767) Supervisor: Professor Neville H McClenaghan April 2010
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7. Figure 1: Effects of prolonged (18 hour) exposure to homocysteine without or with alloxan and taurine on glucose phosphorylation Values are mean ± S.E.M. (n = 8). **P<0.01, ***P<0.001 compared to 100 mM glucose (GK activity) of control (None). ΔΔ P<0.01 compared to HC + Ax. Abbreviations: HC, homocysteine; Ax, alloxan, Tau, taurine.
8. Figure 2: Effects of prolonged (18 hour) exposure to homocysteine thiolactone without or with alloxan and taurine on glucose phosphorylation Values are mean ± S.E.M. (n = 8). ***P<0.001 compared to 100 mM glucose (GK activity) of control (None). ΔΔ P<0.01 compared to HCTL + Ax. Abbreviations: HCTL, homocysteine thiolactone; Ax, alloxan, Tau, taurine.
9. Figure 3: Effect of prolonged (18 hour) exposure to cysteine without or with alloxan and taurine on glucose phosphorylation Values are mean ± S.E.M. (n = 8). ***P<0.001 compared to 100 mM glucose (GK activity) of control (None). ΔΔΔ P<0.01 compared to Cys + Ax. Abbreviations: Cys, cysteine; Ax, alloxan, Tau, taurine.
10. Figure 4: Effects of prolonged (18 hour) exposure to cysteic acid without or with alloxan and taurine on glucose phosphorylation Values are mean ± S.E.M. (n = 8). **P<0.01, ***P<0.001 compared to 100 mM glucose (GK activity) of control (None). ΔΔ P<0.01 compared to CysA + Ax. Abbreviations: CysA, cysteic acid; Ax, alloxan, Tau, taurine.