In this presentation, I described what Quantum Annealing is and how you can use it in the field of Protein Folding and Drug Discovery

1. QUANTUM
ANNEALING FOR
PROTEIN FOLDING &
DRUG DISCOVERY

2. WHAT ARE SOME
DISEASES WHERE WE
STILL DON'T HAVE A
SOLUTION FOR?

4. MORE THAN 60 MILLION
PEOPLE ARE IMPACTED BY
THESE DISEASES
Note: It's almost the size of France

5. UNFOLDED OR DAMAGED
PROTEIN AGGREGATIONS
CAN HAVE A CYTOTOXIC
EFFECT

6. Levinthal’s Paradox
How does protein folding happens so
rapidly?
How we end up having the same protein
conformations?

7. PHYSICAL
PROBLEM
COMPUTATIONAL
PROBLEM

8. We start from different conformations and we
end up by having one of them
PHYSICAL PROBLEM

9. Computing the full electronic wavefunction of
an average drug molecule numerically is
expected to take longer than the age of the
universe on any current supercomputers
COMPUTATIONAL PROBLEM

10. CONVENTIONAL APPROACH TO
PROTEIN FOLDING
Using Machine Learning to Predict Protein
Sequences

11. WHAT IF THE SIZE OF THE
PROBLEM BECOMES LARGER
THAN THAT?

12. WE NEED TO FIND
THE GLOBAL
MINIMUM

13. QUANTUM ANNEALING TO FIND
THE GLOBAL MINIMUM

14. PILLARS FOR
QUANTUM ANNEALING
The Hamiltonian
The Eigenspectrum

15. THE HAMILTONIAN
Image from D-Wave

16. THE EIGENSPECTRUM
Image from D-Wave

17. MONTE CARLO METHOD

18. WAYS WE
MEASURE GLOBAL
MINIMUM

19. "TURN ANCILLA" CONSTRUCTION

20. We map Proteins into a bidimensional
system because we would not have
enough qubits to do in other ways.
A three-dimensional space would
require Nlog(N) qubits.
N is the number of amino acids

21. INSING-TYPE HAMILTONIAN
ENCODING

22. FUTURE
POSSIBILITIES