QOPI (Quality Oncology Practice Initiative) is a program developed by the American Society of Clinical Oncology (ASCO) that uses a set of measures to evaluate and improve the quality of care in outpatient chemotherapy clinics. There are three levels of participation in QOPI - unregistered, registered, and certification. For certification, clinics must participate in data collection, meet scoring requirements on 26 core measures, and pass an on-site review. QOPI measures overlap with COC standards and can be used to fulfill eligibility requirements or conduct quality studies. Participation in QOPI also provides career opportunities for cancer registrars given their skills in data collection, analysis, and quality improvement.