This document provides an overview of searching PubMed: I. PubMed searches the MEDLINE database and provides access to over 21 million records and abstracts indexed with MeSH headings. II. MeSH (Medical Subject Headings) allows articles on the same topic to be found even if they use different words, through standardized subject terms. III. When searching PubMed, keywords are matched to MeSH terms to broaden results, and search filters can then focus results; searching for a term as a MeSH Major Topic limits to articles where it is a primary topic.