This document summarizes research on imidazole-containing peptides and their potential applications in treating age-related eye diseases. It discusses several research articles and patents related to using carnosine and its derivatives to prevent and treat cataracts. Specifically, it describes research showing these compounds can inhibit amyloid fibril formation, protect lens proteins from oxidative stress, and help restore lens transparency in cataractous lenses. The document concludes these compounds show promise as antioxidants for defending the eye from oxidative stresses that can lead to cataracts and other ocular complications.
A model for homeopathic remedy effects: low dose nanoparticles, allostatic cr...home
The proposed active components of homeopathic remedies are nanoparticles of source substance in
water-based colloidal solution, not bulk-form drugs. Nanoparticles have unique biological and physico-chemical
properties, including increased catalytic reactivity, protein and DNA adsorption, bioavailability, dose-sparing,
electromagnetic, and quantum effects different from bulk-form materials. Trituration and/or liquid succussions
during classical remedy preparation create “top-down” nanostructures. Plants can biosynthesize remedy-templated
silica nanostructures. Nanoparticles stimulate hormesis, a beneficial low-dose adaptive response. Homeopathic
remedies prescribed in low doses spaced intermittently over time act as biological signals that stimulate the
organism’s allostatic biological stress response network, evoking nonlinear modulatory, self-organizing change.
Potential mechanisms include time-dependent sensitization (TDS), a type of adaptive plasticity/metaplasticity
involving progressive amplification of host responses, which reverse direction and oscillate at physiological limits.
To mobilize hormesis and TDS, the remedy must be appraised as a salient, but low level, novel threat, stressor, or
homeostatic disruption for the whole organism. Silica nanoparticles adsorb remedy source and amplify effects.
Properly-timed remedy dosing elicits disease-primed compensatory reversal in direction of maladaptive dynamics of
the allostatic network, thus promoting resilience and recovery from disease.
A model for homeopathic remedy effects: low
dose nanoparticles, allostatic cross-adaptation,
and time-dependent sensitization in a complex
adaptive system
A model for homeopathic remedy effects: low dose nanoparticles, allostatic cr...home
The proposed active components of homeopathic remedies are nanoparticles of source substance in
water-based colloidal solution, not bulk-form drugs. Nanoparticles have unique biological and physico-chemical
properties, including increased catalytic reactivity, protein and DNA adsorption, bioavailability, dose-sparing,
electromagnetic, and quantum effects different from bulk-form materials. Trituration and/or liquid succussions
during classical remedy preparation create “top-down” nanostructures. Plants can biosynthesize remedy-templated
silica nanostructures. Nanoparticles stimulate hormesis, a beneficial low-dose adaptive response. Homeopathic
remedies prescribed in low doses spaced intermittently over time act as biological signals that stimulate the
organism’s allostatic biological stress response network, evoking nonlinear modulatory, self-organizing change.
Potential mechanisms include time-dependent sensitization (TDS), a type of adaptive plasticity/metaplasticity
involving progressive amplification of host responses, which reverse direction and oscillate at physiological limits.
To mobilize hormesis and TDS, the remedy must be appraised as a salient, but low level, novel threat, stressor, or
homeostatic disruption for the whole organism. Silica nanoparticles adsorb remedy source and amplify effects.
Properly-timed remedy dosing elicits disease-primed compensatory reversal in direction of maladaptive dynamics of
the allostatic network, thus promoting resilience and recovery from disease.
A model for homeopathic remedy effects: low
dose nanoparticles, allostatic cross-adaptation,
and time-dependent sensitization in a complex
adaptive system
Dr. Mark A. Babizhayev Drug Design of Mitochondria-Targeted Antioxidants, Action, Metabolism and Perspectives for
Ophthalmic Therapeutics: N-acetylcarnosine Codrug Treatment Platform - Int J Ophthalmol Eye Res. 2017 5(4), 287-307.
Babizhayev MA: Drug Design of Mitochondria-Targeted Antioxidants, Action, Met...Mark Babizhayev
Babizhayev MA Drug Design of Mitochondria-Targeted Antioxidants, Action, Metabolism and Perspectives for
Ophthalmic Therapeutics: N-acetylcarnosine Codrug Treatment Platform International Journal of Ophthalmology & Eye Science
recent advances in pharmacotherapy of Glaucoma DrShrey Bhatia
new drugs, potential targets, recent trends for glaucoma treatment. important new target have been discussed along with current therapies. good enough for post graduate teaching and undergraduate classes.
Natural products as a crucial source of anti-inflammatory drugs: recent trend...LucyPi1
Abstract Natural active molecules are key sources of modern innovative drugs. Particularly, a great amount of natural active molecules have been reported to possess promising therapeutic effects on inflammatory diseases, including asthma, rheumatoid arthritis, hepatitis, enteritis, metabolic disorders and neurodegenerative diseases. However, these natural active molecules with various molecular structures usually exert anti-inflammatory effects through diversiform pharmacological mechanisms, which is necessary to be summarized systematically. In this review, we introduced the current major anti-inflammatory natural active molecules based on their chemical structures, and discussed their pharmacological mechanisms including anti-inflammatory molecular signaling pathways and potential target proteins, which providing a referential significance on the development of novel anti-inflammatory drugs, and also revealing new therapeutic strategies for inflammatory diseases.
The "Cady White Paper" Review & Rationale for Antioxidant and Nutrient supple...Louis Cady, MD
In this presentation, delivered at the 2nd Health Care Professional Summit in Los Angeles, CA - 9 24 2011 - Dr. Cady reviews the critical points in the Cady White Paper on the Biophotonic Scanner, as well as a cogent explanation from the literature about the need to monitor antioxidant status and supplement appropriately.
A brief description of all topics to recent advances,SDD, host modulation and diabetes, host modulation in smokers, chemically modified tetracyclines, bisphosphonates
Advanced Glycation End Products: Free Radical Generation by Early Glycation Products as a Mechanism for Long-Term Complications of Diabetes Mellitus: Toxicity, Regulation, Function and Role in Health, Nutrition and DiseaseMark A Babizhayev*Innovative Vision Products, County of New Castle, Delaware, USAReceived March 19, 2017; Accepted April 26, 2017; Published May 03, 2017*Corresponding author: Dr. Mark A Babizhayev, Innovative Vision Products, Inc., Moscow Division, Ivanovskaya 20, Suite 74 Moscow 127434 Russian Federation, County of New Castle, Delaware, USA; Tel: +7(499) 977-2387; E-mail: markbabizhayev@mail.ru Citation: Babizhayev MA (2017) Advanced Glycation End Products: Free Radical Generation by Early Glycation Products as a Mechanism for Long-Term Complications of Diabetes Mellitus: Toxicity, Regulation, Function and Role in Health, Nutrition and Disease. Qual Prim Health Care (2017) 1:1 001
Babizhayev MA (2017) Advanced Glycation End Products: Free Radical Generation by Early Glycation Products as a
Mechanism for Long-Term Complications of Diabetes Mellitus: Toxicity, Regulation, Function and Role in Health, Nutrition and
Disease. Qual Prim Health Care (2017) 1:1 001
Babizhayev MA (2017) Treatment of Skin Aging and Photoaging with Innovative O...Mark Babizhayev
Babizhayev MA (2017) Treatment of Skin Aging and Photoaging with Innovative Oral Dosage Forms of Non-Hydrolized Carnosine and Carcinine. Int J Clin Dermatol Res. 5(5), 116-143.
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Dr. Mark A. Babizhayev Drug Design of Mitochondria-Targeted Antioxidants, Action, Metabolism and Perspectives for
Ophthalmic Therapeutics: N-acetylcarnosine Codrug Treatment Platform - Int J Ophthalmol Eye Res. 2017 5(4), 287-307.
Babizhayev MA: Drug Design of Mitochondria-Targeted Antioxidants, Action, Met...Mark Babizhayev
Babizhayev MA Drug Design of Mitochondria-Targeted Antioxidants, Action, Metabolism and Perspectives for
Ophthalmic Therapeutics: N-acetylcarnosine Codrug Treatment Platform International Journal of Ophthalmology & Eye Science
recent advances in pharmacotherapy of Glaucoma DrShrey Bhatia
new drugs, potential targets, recent trends for glaucoma treatment. important new target have been discussed along with current therapies. good enough for post graduate teaching and undergraduate classes.
Natural products as a crucial source of anti-inflammatory drugs: recent trend...LucyPi1
Abstract Natural active molecules are key sources of modern innovative drugs. Particularly, a great amount of natural active molecules have been reported to possess promising therapeutic effects on inflammatory diseases, including asthma, rheumatoid arthritis, hepatitis, enteritis, metabolic disorders and neurodegenerative diseases. However, these natural active molecules with various molecular structures usually exert anti-inflammatory effects through diversiform pharmacological mechanisms, which is necessary to be summarized systematically. In this review, we introduced the current major anti-inflammatory natural active molecules based on their chemical structures, and discussed their pharmacological mechanisms including anti-inflammatory molecular signaling pathways and potential target proteins, which providing a referential significance on the development of novel anti-inflammatory drugs, and also revealing new therapeutic strategies for inflammatory diseases.
The "Cady White Paper" Review & Rationale for Antioxidant and Nutrient supple...Louis Cady, MD
In this presentation, delivered at the 2nd Health Care Professional Summit in Los Angeles, CA - 9 24 2011 - Dr. Cady reviews the critical points in the Cady White Paper on the Biophotonic Scanner, as well as a cogent explanation from the literature about the need to monitor antioxidant status and supplement appropriately.
A brief description of all topics to recent advances,SDD, host modulation and diabetes, host modulation in smokers, chemically modified tetracyclines, bisphosphonates
Advanced Glycation End Products: Free Radical Generation by Early Glycation Products as a Mechanism for Long-Term Complications of Diabetes Mellitus: Toxicity, Regulation, Function and Role in Health, Nutrition and DiseaseMark A Babizhayev*Innovative Vision Products, County of New Castle, Delaware, USAReceived March 19, 2017; Accepted April 26, 2017; Published May 03, 2017*Corresponding author: Dr. Mark A Babizhayev, Innovative Vision Products, Inc., Moscow Division, Ivanovskaya 20, Suite 74 Moscow 127434 Russian Federation, County of New Castle, Delaware, USA; Tel: +7(499) 977-2387; E-mail: markbabizhayev@mail.ru Citation: Babizhayev MA (2017) Advanced Glycation End Products: Free Radical Generation by Early Glycation Products as a Mechanism for Long-Term Complications of Diabetes Mellitus: Toxicity, Regulation, Function and Role in Health, Nutrition and Disease. Qual Prim Health Care (2017) 1:1 001
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Babizhayev MA (2017) Advanced Glycation End Products: Free Radical Generation by Early Glycation Products as a
Mechanism for Long-Term Complications of Diabetes Mellitus: Toxicity, Regulation, Function and Role in Health, Nutrition and
Disease. Qual Prim Health Care (2017) 1:1 001
Babizhayev MA (2017) Treatment of Skin Aging and Photoaging with Innovative O...Mark Babizhayev
Babizhayev MA (2017) Treatment of Skin Aging and Photoaging with Innovative Oral Dosage Forms of Non-Hydrolized Carnosine and Carcinine. Int J Clin Dermatol Res. 5(5), 116-143.
An issue of argue with "Progress in Biophysics and Molecular Biology" (the Jo...Mark Babizhayev
An Issue of Argue with "Progress in Biophysics and Molecular Biology"(the Journal of Elsevier Publisher), Xin Ni, Ph.D Special Issue Guest Editor Progress in Biophysics and Molecular Biology
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These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
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Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
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Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Anti ulcer drugs and their Advance pharmacology ||
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- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
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Surgical Site Infections, pathophysiology, and prevention.pptx
Publications 1 to dr. mark a. babizhayev
1. 1
An investment in knowledge pays the best interest.
Benjamin Franklin
Publications to Dr. Mark A. Babizhayev in PubMed Results: 88 + 36
Pre-PubMed cited Issued Recent Articles
Imidazole-containing peptide-based compounds in sight-
threatening age-related eye diseases
Article in: Expert Review of Ophthalmology 4(6):581-586 · December
2009
1st Mark A Babizhayev
· Innovative Vision Products, Inc.
2nd Anne Kasus-Jacobi
2. 2
University of Oklahoma Health Sciences Center
Abstract
Evaluation of: Attanasio F, Cataldo S, Fisichella S et al. Protective effects of L- and D-
carnosine on α-crystallin amyloid fibril formation: implications for cataract disease.
Biochemistry 48(27), 6522-6531 (2009).We shall evaluate a paper examining protective
and therapeutic significance of carnosine derivatives that have been formerly proposed
as potent agents for ophthalmic therapies of senile cataracts and diabetic ocular
complications. The authors report the inhibitory effect induced by the racemized
carnosine peptides (L- and D-enantiomeric forms) on the modulation of fibrillation of
cataract disease-related α-crystallin. The latter molecular chaperone protects against
the unfolding and aggregation of lens crystallins and oxidative stress toxicity to the lens
proteins. The authors have found a disassembling effect of racemized carnosine forms
on α-crystallin amyloid fibrils, and the almost complete restoration of the chaperone
activity lost has been revealed after denaturant and/or heat stress. This article supports
the ability of carnosine dipeptide to restore most of the lens transparency in cataractous
lenses (short-term organ-cultured rat lenses). The entire body of supporting published
research on N-acetylcarnosine and its bioactivated principle carnosine reveals its
promise as a water-soluble universal antioxidant that works at several levels to defend
against the oxidative stresses to the lens and glycosylation problems, and to protect the
lens proteins and the membrane lipids from oxidative damages, thus preventing and
reversing age-related cataract in human eyes.
http://endnote.com/downloads/style/expert-review-ophthalmology
Mark A. Babizhayev and Yegor E Yegorov
Telomere Attrition in Human Lens Epithelial Cells Associated with
Oxidative Stress Provide a New Therapeutic Target for the Treatment,
Dissolving and Prevention of Cataract with N-Acetylcarnosine
Lubricant Eye Drops. Kinetic, Pharmacological and Activity-Dependent
Separation of Therapeutic Targeting: Transcorneal Penetration and
Delivery of L-Carnosine in the Aqueous Humor and Hormone-Like
Hypothalamic Antiaging Effects of the Instilled Ophthalmic Drug
Through a Safe Eye Medication Technique
Recent Patents on Drug Delivery & Formulation
2016 , 10(2): 82 – 129
DOI: 10.2174/1872211309666150618104657
http://benthamscience.com/journal/index.php?journalID=rpddf
3. 3
Mark A. Babizhayev Generation of reactive oxygen species in the
anterior eye segment. Synergistic codrugs of N-acetylcarnosine lubricant
eye drops and mitochondria-targeted antioxidant act as a powerful
therapeutic platform for the treatment of cataracts and primary open-
angle glaucoma
BBA Clinical
Volume 6, December 2016, Pages 49–68
http://ac.els-cdn.com/S2214647416300186/1-s2.0-
S2214647416300186-main.pdf?_tid=a5a34cb0-455a-11e6-8e6f-
00000aab0f6c&acdnat=1468016811_c8e06bc640752e65e97835df672
8a9a5
First PubMed Results: 88
1.
Generation of reactive oxygen species in the anterior eye segment.
Synergistic codrugs of N-acetylcarnosine lubricant eye drops and
mitochondria-targeted antioxidant act as a powerful therapeutic platform
for the treatment of cataracts and primary open-angle glaucoma.
Babizhayev MA.
BBA Clin. 2016 Apr 19;6:49-68. doi: 10.1016/j.bbacli.2016.04.004.
eCollection 2016 Dec. Review.
4. 4
PMID:
27413694 Free PMC Article
Similar articles
Select item 26372004 2.
Patenting strategies, the authentication US fiscal methodology,
discovery and development of imidazole-containing peptide compounds
with free-radical scavenging and transglycating properties acting as
targeted drug regulators and homeostatic agents with diverse therapeutic
activities for pharmacy of diabetes and metabolic diseases.
Babizhayev MA.
Expert Opin Ther Pat. 2015 Nov;25(11):1319-39. doi:
10.1517/13543776.2015.1064899. Epub 2015 Sep 15.
PMID:
26372004
Similar articles
5. 5
Select item 26084629 3.
Telomere Attrition in Human Lens Epithelial Cells Associated with
Oxidative Stress Provide a New Therapeutic Target for the Treatment,
Dissolving and Prevention of Cataract with N-Acetylcarnosine
Lubricant Eye Drops. Kinetic, Pharmacological and Activity-Dependent
Separation of Therapeutic Targeting: Transcorneal Penetration and
Delivery of L-Carnosine in the Aqueous Humor and Hormone-Like
Hypothalamic Antiaging Effects of the Instilled Ophthalmic Drug
Through a Safe Eye Medication Technique.
Babizhayev MA, Yegorov YE.
Recent Pat Drug Deliv Formul. 2015 Jun 17. [Epub ahead of print]
PMID:
26084629
Similar articles
Select item 26034007 4.
Tissue formation and tissue engineering through host cell recruitment or
a potential injectable cell-based biocomposite with replicative potential:
Molecular mechanisms controlling cellular senescence and the
involvement of controlled transient telomerase activation therapies.
Babizhayev MA, Yegorov YE.
J Biomed Mater Res A. 2015 Dec;103(12):3993-4023. doi:
10.1002/jbm.a.35515. Epub 2015 Aug 14. Review.
PMID:
26034007
Similar articles
Select item 25625945 5.
6. 6
Functional Performance of L-Carnosine ( -Alanyl-L-Histidine) and
Related Imidazole-Containing Dipeptides. Design and Modern
Applications of Drug Delivery Systems (Nanosuspensions of Nanosize
Materials, Mucoadhesive Drug Delivery Systems, Formulations of
Transdermal Patches for Controlled Drug Delivery) Leads to Functional
Recovery in Ischemic Stroke.
Babizhayev MA.
Recent Pat Drug Deliv Formul. 2015 Jan 26. [Epub ahead of print] No
abstract available.
PMID:
25625945
[PubMed - as supplied by publisher]
Related citations
Select item 25524476 6.
An "Enigmatic" L-Carnosine (β-Alanyl-L-Histidine)? Cell Proliferative
Activity as a Fundamental Property of a Natural Dipeptide Inherent to
Traditional Antioxidant, Anti-Aging Biological Activities: Balancing
and a Hormonally Correct Agent, Novel Patented Oral Therapy Dosage
Formulation for Mobility, Skeletal Muscle Power and Functional
Performance, Hypothalamic-Pituitary- Brain Relationship in Health,
Aging and Stress Studies.
Babizhayev MA, Yegorov YE.
Recent Pat Drug Deliv Formul. 2015;9(1):1-64.
PMID:
25524476
[PubMed - in process]
Related citations
7. 7
Select item 25427889 7.
The Role of Oxidative Stress in Diabetic Neuropathy: Generation of
Free Radical Species in the Glycation Reaction and Gene
Polymorphisms Encoding Antioxidant Enzymes to Genetic
Susceptibility to Diabetic Neuropathy in Population of Type I Diabetic
Patients.
Babizhayev MA, Strokov IA, Nosikov VV, Savel'yeva EL, Sitnikov
VF, Yegor E Yegorov, Lankin VZ.
Cell Biochem Biophys. 2014 Nov 27. [Epub ahead of print]
PMID:
25427889
[PubMed - as supplied by publisher]
Select item 25158972 8.
Biochemical, Biomedical and Metabolic Aspects of Imidazole-
Containing Dipeptides with the Inherent Complexity to
Neurodegenerative Diseases and Various States of Mental Well-Being:
A Challenging Correction and Neurotherapeutic Pharmaceutical
8. 8
Biotechnology for Treating Cognitive Deficits, Depression and
Intellectual Disabilities.
Babizhayev MA.
Curr Pharm Biotechnol. 2014;15(8):738-78.
PMID:
25158972
Similar articles
10. 10
Hormone-brain-aging relationships, broadly reactive with imidazole-
containing dipeptides: targeting of telomere attrition as an aging
biomarker and dynamic telomerase activity flirting.
Babizhayev MA, Vishnyakova KS, Yegorov YE.
J Basic Clin Physiol Pharmacol. 2015 Mar 1;26(2):115-40. doi:
10.1515/jbcpp-2014-0045.
PMID:
25153587
[PubMed - in process]
Related citations
Select item 24910283 10.
Novel neuroendocrine and metabolic mechanism provides the patented
platform for important rejuvenation therapies: targeted therapy of
telomere attrition and lifestyle changes of telomerase activity with the
timing of neuron-specific imidazole-containing dipeptide-dominant
pharmaconutrition provision.
Babizhayev MA, Kasus-Jacobi A, Vishnyakova KS, Yegorov YE.
Recent Pat Endocr Metab Immune Drug Discov. 2014;8(3):153-79.
PMID:
24910283
[PubMed - in process]
Related citations
Select item 24894799
11.
11. 11
Oxidative damage impact on aging and age-related diseases: drug
targeting of telomere attrition and dynamic telomerase activity flirting
with imidazole-containing dipeptides.
Babizhayev MA, Vishnyakova KS, Yegorov YE.
Recent Pat Drug Deliv Formul. 2014;8(3):163-92.
PMID:
24894799
[PubMed - in process]
Related citations
Select item 24801384
12.
Editorial: insight into the patent reviews and recent studies on
nanotechnology and allied technology platforms for biomedical
engineering and pharmaceutical drug delivery dosage forms.
Babizhayev MA.
12. 12
Recent Pat Drug Deliv Formul. 2014 Apr;8(1):1-2. No abstract
available.
PMID:
24801384
[PubMed - in process]
Related citations
Select item 24236935
13.
Diabetes mellitus: novel insights, analysis and interpretation of
pathophysiology and complications management with imidazole-
containing peptidomimetic antioxidants.
Babizhayev MA, Lankin VZ, Savel'yeva EL, Deyev AI, Yegorov YE.
Recent Pat Drug Deliv Formul. 2013 Dec;7(3):216-56.
PMID:
24236935
[PubMed - in process]
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13. 13
Select item 24220875
14.
The detox strategy in smoking comprising nutraceutical formulas of
non-hydrolyzed carnosine or carcinine used to protect human health.
14. 14
Babizhayev MA.
Hum Exp Toxicol. 2014 Mar;33(3):284-316. doi:
10.1177/0960327113493306. Epub 2013 Nov 12.
PMID:
24220875
[PubMed - in process]
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Select item 24093642
15.
Biomarkers of Oxidative Stress and Cataract. Novel Drug Delivery
Therapeutic Strategies Targeting Telomere Reduction and the
Expression of Telomerase Activity in the Lens Epithelial Cells with N-
15. 15
Acetylcarnosine Lubricant Eye Drops: Anti-Cataract which Helps to
Prevent and Treat Cataracts in the Eyes of Dogs and other Animals.
Babizhayev MA, Yegorov YE.
Curr Drug Deliv. 2014 Feb ;11(1):24-61.
PMID:
24093642
[PubMed - as supplied by publisher]
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16.
L-Carnosine modulates respiratory burst and reactive oxygen species
production in neutrophil biochemistry and function: may oral dosage
form of non-hydrolized dipeptide L-carnosine complement anti-infective
anti-influenza flu treatment, prevention and self-care as an alternative to
the conventional vaccination?
Babizhayev MA, Deyev AI, Yegorov YE.
Curr Clin Pharmacol. 2014 May; 9(2):93-115.
PMID:
23441838
[PubMed - in process]
16. 16
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17.
Non-hydrolyzed in digestive tract and blood natural L-carnosine peptide
("bioactivated Jewish penicillin") as a panacea of tomorrow for various
flu ailments: signaling activity attenuating nitric oxide (NO) production,
cytostasis, and NO-dependent inhibition of influenza virus replication in
macrophages in the human body infected with the virulent swine
influenza A (H1N1) virus.
Babizhayev MA, Deyev AI, Yegorov YE.
J Basic Clin Physiol Pharmacol. 2013;24(1):1-26. doi: 10.1515/jbcpp-
2012-0037. Review.
PMID:
23425625
[PubMed - indexed for MEDLINE]
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18.
Focus on biomaterial technologies and nanotechnology with the
emphasis on the perspectives in stem cell tissue, pharmaceutical co-
processed excipients and medical device biomedical engineering.
17. 17
Babizhayev MA.
Recent Pat Drug Deliv Formul. 2013 Apr;7(1):1-2. No abstract
available.
PMID:
23244682
[PubMed - indexed for MEDLINE]
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Select item 22934629
19.
Coated with nanomaterials intraocular lenses, ophthalmic and human
body implantable devices with high catalytic antioxidant activities: a
new nanotechnology strategy of peroxidase cellular enzyme mimics
increasing the biocompatibility and therapeutic deployment of the
medical prosthetic device.
Babizhayev MA.
Recent Pat Drug Deliv Formul. 2013 Apr;7(1):39-65.
PMID:
22934629
[PubMed - indexed for MEDLINE]
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20.
Carcinine has 4-hydroxynonenal scavenging property and
neuroprotective effect in mouse retina.
Marchette LD, Wang H, Li F, Babizhayev MA, Kasus-Jacobi A.
18. 18
Invest Ophthalmol Vis Sci. 2012 Jun 20;53(7):3572-83. doi:
10.1167/iovs.11-9042.
PMID:
22577078
[PubMed - indexed for MEDLINE]
Free PMC Article
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21.
Structural and functional properties, chaperone activity and
posttranslational modifications of alpha-crystallin and its related
subunits in the crystalline lens: N-acetylcarnosine, carnosine and
carcinine act as alpha- crystallin/small heat shock protein enhancers in
prevention and dissolution of cataract in ocular drug delivery
formulations of novel therapeutic agents.
Babizhayev MA.
Recent Pat Drug Deliv Formul. 2012 Aug;6(2):107-48. Review.
PMID:
22436026
[PubMed - indexed for MEDLINE]
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22.
Olfactory dysfunction and cognitive impairment in age-related
neurodegeneration: prevalence related to patient selection, diagnostic
criteria and therapeutic treatment of aged clients receiving clinical
neurology and community-based care.
Babizhayev MA, Deyev AI, Yegorov YE.
Curr Clin Pharmacol. 2011 Nov;6(4):236-59. Review.
PMID:
22082323
19. 19
[PubMed - indexed for MEDLINE]
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23.
Biomarkers and special features of oxidative stress in the anterior
segment of the eye linked to lens cataract and the trabecular meshwork
injury in primary open-angle glaucoma: challenges of dual combination
therapy with N-acetylcarnosine lubricant eye drops and oral formulation
of nonhydrolyzed carnosine.
Babizhayev MA.
Fundam Clin Pharmacol. 2012 Feb; 26(1):86-117. doi: 10.1111/j.1472-
8206.2011.00969.x. Epub 2011 Aug 24. Review.
PMID:
21883446
[PubMed - indexed for MEDLINE]
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24.
20. 20
Novel intraocular and systemic absorption drug delivery and efficacy of
N-acetylcarnosine lubricant eye drops or carcinine biologics in
pharmaceutical usage and therapeutic vision care.
Babizhayev MA, Khoroshilova-Maslova IP, Kasus-Jacobi A.
Fundam Clin Pharmacol. 2012 Oct;26(5):644-78. doi: 10.1111/j.1472-
8206.2011.00963.x. Epub 2011 Jul 27.
PMID:
21793899
[PubMed - indexed for MEDLINE]
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25.
Skin beautification with oral non-hydrolized versions of carnosine and
carcinine: Effective therapeutic management and cosmetic skincare
solutions against oxidative glycation and free-radical production as a
causal mechanism of diabetic complications and skin aging.
Babizhayev MA, Deyev AI, Savel'yeva EL, Lankin VZ, Yegorov YE.
J Dermatolog Treat. 2012 Oct;23(5):345-84. doi:
10.3109/09546634.2010.521812. Epub 2011 Jul 14.
PMID:
21756141
[PubMed - in process]
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26.
Senescent phenotype of trabecular meshwork cells displays biomarkers
in primary open-angle glaucoma.
Babizhayev MA, Yegorov YE.
Curr Mol Med. 2011 Oct;11(7):528-52.
21. 21
PMID:
21707516
[PubMed - indexed for MEDLINE]
Related citations
27.
Water-structuring technology with the molecular chaperone proteins:
indicated application of the α-crystallin domains and imidazole-
containing peptidomimetics in cosmetic skin care systems or
dermatological therapeutic drug carrier formulations.
Babizhayev MA, Nikolayev GM, Nikolayeva JG, Yegorov YE.
Crit Rev Ther Drug Carrier Syst. 2011;28(3):203-53.
PMID:
21663576
[PubMed - indexed for MEDLINE]
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28.
Bioactivation antioxidant and transglycating properties of N-
acetylcarnosine autoinduction prodrug of a dipeptide L-carnosine in
mucoadhesive drug delivery eye-drop formulation: powerful eye health
application technique and therapeutic platform.
Babizhayev MA.
Drug Test Anal. 2012 Jun;4(6):468-85. doi: 10.1002/dta.265. Epub 2011
Mar 18.
PMID:
21416634
[PubMed - indexed for MEDLINE]
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22. 22
29.
Mitochondria induce oxidative stress, generation of reactive oxygen
species and redox state unbalance of the eye lens leading to human
cataract formation: disruption of redox lens organization by
phospholipid hydroperoxides as a common basis for cataract disease.
Babizhayev MA.
Cell Biochem Funct. 2011 Apr;29(3):183-206. doi: 10.1002/cbf.1737.
Epub 2011 Mar 7.
PMID:
21381059
[PubMed - indexed for MEDLINE]
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30.
Reactive Oxygen Species and the Aging Eye: Specific Role of
Metabolically Active Mitochondria in Maintaining Lens Function and in
the Initiation of the Oxidation-Induced Maturity Onset Cataract-A Novel
Platform of Mitochondria-Targeted Antioxidants With Broad
Therapeutic Potential for Redox Regulation and Detoxification of
Oxidants in Eye Diseases.
Babizhayev MA, Yegorov YE.
Am J Ther. 2016 Jan-Feb;23(1):e98-e117. doi:
10.1097/MJT.0b013e3181ea31ff.
PMID:
21048433
Similar articles
31.
23. 23
Advanced drug delivery of N-acetylcarnosine (N-acetyl-beta-alanyl-L-
histidine), carcinine (beta-alanylhistamine) and L-carnosine (beta-
alanyl-L-histidine) in targeting peptide compounds as pharmacological
chaperones for use in tissue engineering, human disease management
and therapy: from in vitro to the clinic.
Babizhayev MA, Yegorov YE.
Recent Pat Drug Deliv Formul. 2010 Nov;4(3):198-230. Review.
PMID:
20863274
[PubMed - indexed for MEDLINE]
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32.
Biologic activities of molecular chaperones and pharmacologic
chaperone imidazole-containing dipeptide-based compounds: natural
skin care help and the ultimate challenge: implication for adaptive
responses in the skin.
Babizhayev MA, Nikolayev GM, Nikolayeva JG, Yegorov YE.
Am J Ther. 2012 Mar;19(2):e69-89. doi:
10.1097/MJT.0b013e3181e71fb7. Review.
PMID:
20861720
[PubMed - indexed for MEDLINE]
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33.
Management of the virulent influenza virus infection by oral formulation
of nonhydrolized carnosine and isopeptide of carnosine attenuating
proinflammatory cytokine-induced nitric oxide production.
Babizhayev MA, Deyev AI.
24. 24
Am J Ther. 2012 Jan;19(1):e25-47. doi:
10.1097/MJT.0b013e3181dcf589. Review.
PMID:
20841992
[PubMed - indexed for MEDLINE]
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34.
Smoking and health: association between telomere length and factors
impacting on human disease, quality of life and life span in a large
population-based cohort under the effect of smoking duration.
Babizhayev MA, Yegorov YE.
Fundam Clin Pharmacol. 2011 Aug;25(4):425-42. doi: 10.1111/j.1472-
8206.2010.00866.x. Epub 2010 Aug 4. Review.
PMID:
20698892
[PubMed - indexed for MEDLINE]
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35.
Designation of imidazole-containing dipeptides as pharmacological
chaperones.
Babizhayev MA.
Hum Exp Toxicol. 2011 Jul;30(7):736-61. doi:
10.1177/0960327110377526. Epub 2010 Jul 23. Review.
PMID:
20656726
[PubMed - indexed for MEDLINE]
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25. 25
36.
A survey and analysis of the role of molecular chaperone proteins and
imidazole-containing dipeptide-based compounds as molecular escorts
into the skin during stress, injury, water structuring and other types of
cutaneous pathophysiology.
Babizhayev MA, Nikolayev GM, Nikolayeva JG, Yegorov YE.
Int J Cosmet Sci. 2011 Feb;33(1):1-16. doi: 10.1111/j.1468-
2494.2010.00601.x. Review.
PMID:
20546050
[PubMed - indexed for MEDLINE]
Free Article
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37.
Telomere attrition in lens epithelial cells - a target for N-acetylcarnosine
therapy.
Babizhayev MA, Yegorov YE.
Front Biosci. 2010 Jun 1;15:934-56. Review.
PMID:
20515735
[PubMed - indexed for MEDLINE]
Related citations
38.
Therapeutic uses of drug-carrier systems for imidazole-containing
dipeptide compounds that act as pharmacological chaperones and have
significant impact on the treatment of chronic diseases associated with
increased oxidative stress and the formation of advanced glycation end
products.
26. 26
Babizhayev MA, Yegorov YE.
Crit Rev Ther Drug Carrier Syst. 2010;27(2):85-154. Review.
PMID:
20486899
[PubMed - indexed for MEDLINE]
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39.
New concept in nutrition for the maintenance of the aging eye redox
regulation and therapeutic treatment of cataract disease; synergism of
natural antioxidant imidazole-containing amino acid-based compounds,
chaperone, and glutathione boosting agents: a systemic perspective on
aging and longevity emerged from studies in humans.
Babizhayev MA.
Am J Ther. 2010 Jul-Aug;17(4):373-89. doi:
10.1097/MJT.0b013e3181d6b6c3. Review.
PMID:
20463577
[PubMed - indexed for MEDLINE]
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40.
Telomere-dependent senescent phenotype of lens epithelial cells as a
biological marker of aging and cataractogenesis: the role of oxidative
stress intensity and specific mechanism of phospholipid hydroperoxide
toxicity in lens and aqueous.
Babizhayev MA, Vishnyakova KS, Yegorov YE.
Fundam Clin Pharmacol. 2011 Apr;25(2):139-62. doi: 10.1111/j.1472-
8206.2010.00829.x. Review.
PMID:
27. 27
20412312
[PubMed - indexed for MEDLINE]
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41.
Telomere length is a biomarker of cumulative oxidative stress, biologic
age, and an independent predictor of survival and therapeutic treatment
requirement associated with smoking behavior.
Babizhayev MA, Savel'yeva EL, Moskvina SN, Yegorov YE.
Am J Ther. 2011 Nov;18(6):e209-26. doi:
10.1097/MJT.0b013e3181cf8ebb. Review.
PMID:
20228673
[PubMed - indexed for MEDLINE]
Related citations
42.
Current ocular drug delivery challenges for N-acetylcarnosine: novel
patented routes and modes of delivery, design for enhancement of
therapeutic activity and drug delivery relationships.
Babizhayev MA.
Recent Pat Drug Deliv Formul. 2009 Nov;3(3):229-65. Review.
PMID:
19534670
[PubMed - indexed for MEDLINE]
Related citations
43.
N-Acetylcarnosine sustained drug delivery eye drops to control the signs
of ageless vision: glare sensitivity, cataract amelioration and quality of
28. 28
vision currently available treatment for the challenging 50,000-patient
population.
Babizhayev MA, Burke L, Micans P, Richer SP.
Clin Interv Aging. 2009;4:31-50. Epub 2009 May 14.
PMID:
19503764
[PubMed - indexed for MEDLINE]
Free PMC Article
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44.
N-acetylcarnosine lubricant eyedrops possess all-in-one universal
antioxidant protective effects of L-carnosine in aqueous and lipid
membrane environments, aldehyde scavenging, and transglycation
activities inherent to cataracts: a clinical study of the new vision-saving
drug N-acetylcarnosine eyedrop therapy in a database population of over
50,500 patients.
Babizhayev MA, Micans P, Guiotto A, Kasus-Jacobi A.
Am J Ther. 2009 Nov-Dec;16(6):517-33. doi:
10.1097/MJT.0b013e318195e327.
PMID:
19487926
[PubMed - indexed for MEDLINE]
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45.
State of the art clinical efficacy and safety evaluation of N-
acetylcarnosine dipeptide ophthalmic prodrug. Principles for the
delivery, self-bioactivation, molecular targets and interaction with a
highly evolved histidyl-hydrazide structure in the treatment and
therapeutic management of a group of sight-threatening eye diseases.
29. 29
Babizhayev MA, Kasus-Jacobi A.
Curr Clin Pharmacol. 2009 Jan;4(1):4-37.
PMID:
19149498
[PubMed - indexed for MEDLINE]
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46.
Potentiation of intraocular absorption and drug metabolism of N-
acetylcarnosine lubricant eye drops: drug interaction with sight
threatening lipid peroxides in the treatment for age-related eye diseases.
Babizhayev MA.
Drug Metabol Drug Interact. 2009;24(2-4):275-323.
PMID:
20408504
[PubMed - indexed for MEDLINE]
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47.
N-Acetylcarnosine and histidyl-hydrazide are potent agents for
multitargeted ophthalmic therapy of senile cataracts and diabetic ocular
complications.
Babizhayev MA, Guiotto A, Kasus-Jacobi A.
J Drug Target. 2009 Jan;17(1):36-63. doi: 10.1080/10611860802438736
.
PMID:
19037813
[PubMed - indexed for MEDLINE]
30. 30
Related citations
48.
Cataract halos: a driving hazard in aging populations. Implication of the
Halometer DG test for assessment of intraocular light scatter.
Babizhayev MA, Minasyan H, Richer SP.
Appl Ergon. 2009 May;40(3):545-53. doi:
10.1016/j.apergo.2007.09.003. Epub 2008 Sep 24.
PMID:
18814857
[PubMed - indexed for MEDLINE]
Related citations
49.
Ocular drug metabolism of the bioactivating antioxidant N-
acetylcarnosine for vision in ophthalmic prodrug and codrug design and
delivery.
Babizhayev MA.
Drug Dev Ind Pharm. 2008 Oct;34(10):1071-89. doi:
10.1080/03639040801958413 .
PMID:
18777243
[PubMed - indexed for MEDLINE]
Related citations
50.
Malondialdehyde scavenging and aldose-derived Schiff bases'
transglycation properties of synthetic histidyl-hydrazide carnosine
analogs.
Guiotto A, Ruzza P, Babizhayev MA, Calderan A.
31. 31
Bioorg Med Chem. 2007 Sep 15;15(18):6158-63. Epub 2007 Jun 20.
PMID:
17604632
[PubMed - indexed for MEDLINE]
Related citations
51.
Biological activities of the natural imidazole-containing
peptidomimetics n-acetylcarnosine, carcinine and L-carnosine in
ophthalmic and skin care products.
Babizhayev MA.
Life Sci. 2006 Apr 11;78(20):2343-57. Epub 2006 Jan 4.
PMID:
16388826
[PubMed - indexed for MEDLINE]
Related citations
52.
Analysis of lipid peroxidation and electron microscopic survey of
maturation stages during human cataractogenesis: pharmacokinetic
assay of Can-C N-acetylcarnosine prodrug lubricant eye drops for
cataract prevention.
Babizhayev MA.
Drugs R D. 2005;6(6):345-69.
PMID:
16274259
[PubMed - indexed for MEDLINE]
Related citations
32. 32
53.
3D molecular modeling, free radical modulating and immune cells
signaling activities of the novel peptidomimetic L-glutamyl-histamine:
possible immunostimulating role.
Babizhayev MA, Semiletov YA, Lul'kin YA, Sakina NL, Savel'yeva
EL, Alimbarova LM, Barinskii IP.
Peptides. 2005 Apr;26(4):551-63. Epub 2004 Dec 29.
PMID:
15752568
[PubMed - indexed for MEDLINE]
Related citations
54.
Immunostimulating activities of the novel peptidomimetic L-glutamyl-
histamine.
Babizhayev MA, Semiletov YA, Lul'kin YA, Sakina NL, Savel'yeva
EL, Alimbarova LM, Barinskii IP.
Clin Exp Immunol. 2005 Mar;139(3):447-57.
PMID:
15730390
[PubMed - indexed for MEDLINE]
Free PMC Article
Related citations
55.
Rejuvenation of visual functions in older adult drivers and drivers with
cataract during a short-term administration of N-acetylcarnosine
lubricant eye drops.
Babizhayev MA.
33. 33
Rejuvenation Res. 2004 Fall;7(3):186-98.
PMID:
15588519
[PubMed - indexed for MEDLINE]
Related citations
56.
Lipid peroxidation and cataracts: N-acetylcarnosine as a therapeutic tool
to manage age-related cataracts in human and in canine eyes.
Babizhayev MA, Deyev AI, Yermakova VN, Brikman IV, Bours J.
Drugs R D. 2004;5(3):125-39. Review.
PMID:
15139774
[PubMed - indexed for MEDLINE]
Related citations
57.
Hydration properties of the molecular chaperone alpha-crystallin in the
bovine lens.
Babizhayev MA, Nikolayev GM, Goryachev SN, Bours J, Martin R.
Biochemistry (Mosc). 2003 Oct;68(10):1145-55.
PMID:
14616086
[PubMed - indexed for MEDLINE]
Related citations
58.
Image analysis and glare sensitivity in human age-related cataracts.
34. 34
Babizhayev MA, Deyev AI, Yermakova VN, Davydova NG, Kurysheva
NI, Doroshenko VS, Zhukotskii AV.
Clin Exp Optom. 2003 May;86(3):157-72.
PMID:
12767250
[PubMed - indexed for MEDLINE]
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59.
Glare disability and driving safety.
Babizhayev MA.
Ophthalmic Res. 2003 Jan-Feb;35(1):19-25.
PMID:
12566859
[PubMed - indexed for MEDLINE]
Related citations
60.
NMR spin-echo studies of hydration properties of the molecular
chaperone alpha-crystallin in the bovine lens.
Babizhayev MA, Nikolayev GN, Goryachev SN, Bours J.
Biochim Biophys Acta. 2002 Jul 29;1598(1-2):46-54.
PMID:
12147343
[PubMed - indexed for MEDLINE]
Related citations
61.
Efficacy of N-acetylcarnosine in the treatment of cataracts.
35. 35
Babizhayev MA, Deyev AI, Yermakova VN, Semiletov YA, Davydova
NG, Doroshenko VS, Zhukotskii AV, Goldman IM.
Drugs R D. 2002;3(2):87-103.
PMID:
12001824
[PubMed - indexed for MEDLINE]
Related citations
36. 36
62.
N-Acetylcarnosine, a natural histidine-containing dipeptide, as a potent
ophthalmic drug in treatment of human cataracts.
Babizhayev MA, Deyev AI, Yermakova VN, Semiletov YA, Davydova
NG, Kurysheva NI, Zhukotskii AV, Goldman IM.
Peptides. 2001 Jun;22(6):979-94.
PMID:
11390029
[PubMed - indexed for MEDLINE]
Related citations
63.
The natural histidine-containing dipeptide Nalpha-acetylcarnosine as an
antioxidant for ophthalmic use.
Babizhayev MA, Yermakova VN, Semiletov YA, Deyev AI.
37. 37
Biochemistry (Mosc). 2000 May;65(5):588-98.
PMID:
10851037
[PubMed - indexed for MEDLINE]
Related citations
64.
Cellular signalling and free-radical modulating activities of the novel
peptidomimetic L-glutamyl-histamine.
Babizhayev MA, Semiletov YA, Lul'kin YA, Sakina NL, Savel'yeva
EL, Deyev AI, Alimbarova LI, Barinskii IF, Nicolay J, Paillet C,
Langrand G, Seguin F.
Biochemistry (Mosc). 1999 May;64(5):510-22.
PMID:
38. 38
10381611
[PubMed - indexed for MEDLINE]
Related citations
65.
Photoprotector and antioxidant properties of histamine-containing
peptidomimetics in the photooxidation of glycyltryptophan.
Babizhayev MA, Lozovskaya EL, Makareyeva EN, Lul'kin YA,
Sapezhinskii II.
Biochemistry (Mosc). 1998 May;63(5):523-8.
PMID:
9632886
[PubMed - indexed for MEDLINE]
Related citations
66.
39. 39
N alpha-acetylcarnosine is a prodrug of L-carnosine in ophthalmic
application as antioxidant.
Babizhayev MA, Yermakova VN, Sakina NL, Evstigneeva RP,
Rozhkova EA, Zheltukhina GA.
Clin Chim Acta. 1996 Oct 15;254(1):1-21. Erratum in: Clin Chim Acta
1997 Mar 18;259(1-2):199-201.
PMID:
8894306
[PubMed - indexed for MEDLINE]
Related citations
67.
Failure to withstand oxidative stress induced by phospholipid
hydroperoxides as a possible cause of the lens opacities in systemic
diseases and ageing.
Babizhayev MA.
Biochim Biophys Acta. 1996 Mar 1;1315(2):87-99.
PMID:
8608175
[PubMed - indexed for MEDLINE]
Related citations
68.
Isoelectric focusing of crystallins in microsections of calf and adult
bovine lens. Identification of water-insoluble crystallins complexing
under nondenaturing conditions: demonstration of chaperone activity of
alpha-crystallin.
Babizhayev MA, Bours J, Utikal KJ.
Ophthalmic Res. 1996;28(6):365-74.
40. 40
PMID:
9032796
[PubMed - indexed for MEDLINE]
Related citations
69.
L-carnosine (beta-alanyl-L-histidine) and carcinine (beta-
alanylhistamine) act as natural antioxidants with hydroxyl-radical-
scavenging and lipid-peroxidase activities.
Babizhayev MA, Seguin MC, Gueyne J, Evstigneeva RP, Ageyeva EA,
Zheltukhina GA.
Biochem J. 1994 Dec 1;304 ( Pt 2):509-16.
PMID:
7998987
[PubMed - indexed for MEDLINE]
Free PMC Article
Related citations
41. 41
70.
Lipid peroxide and reactive oxygen species generating systems of the
crystalline lens.
Babizhayev MA, Costa EB.
Biochim Biophys Acta. 1994 Feb 22;1225(3):326-37.
PMID:
8312381
[PubMed - indexed for MEDLINE]
Related citations
42. 42
71.
Tinting effect of ultraviolet radiation on intraocular lenses of polymethyl
methacrylate.
Babizhayev MA, Chumayevskii NA.
Biomed Mater Eng. 1994;4(1):1-16.
PMID:
7920190
[PubMed - indexed for MEDLINE]
Related citations
72.
Immunohistochemical monitoring of the effect of a synthetic
fibronectin-like peptide (Arg-Gly-Asp) on the age-related changes in the
isolated human corneoscleral tissue of glaucomatous eyes.
Babizhayev MA, Brodskaya MW.
43. 43
Mech Ageing Dev. 1993 Nov;72(1):1-12.
PMID:
7509429
[PubMed - indexed for MEDLINE]
Related citations
73.
Image analysis of the lens opacities induced in developing chick embryo
by glucocorticoid.
Babizhayev MA, Zhukotskii AV, Sologub AA.
Exp Eye Res. 1992 Oct;55(4):521-37.
PMID:
1483499
[PubMed - indexed for MEDLINE]
Related citations
74.
ESR spin label and ultrastructural monitoring of protein-lipid
interactions in the lens fiber-cell plasma membranes in relation to human
ageing and cataractogenesis.
Babizhayev MA, Dainyak BA, Maxina AH.
Mech Ageing Dev. 1992 Jun;64(1-2):133-47.
PMID:
1321312
[PubMed - indexed for MEDLINE]
Related citations
75.
Peroxide-metabolizing systems of the crystalline lens.
44. 44
Babizhayev MA, Deyev AI, Chernikov AV.
Biochim Biophys Acta. 1992 Jan 16;1138(1):11-9. Erratum in: Biochim
Biophys Acta 1992 Jun 9;1139(1-2):167.
PMID:
1737065
[PubMed - indexed for MEDLINE]
Related citations
76.
Changes in fibronectin staining in the human lens during ageing and
cataractogenesis.
Babizhayev MA, Brodskaya MW.
Biochim Biophys Acta. 1991 Feb 22;1096(2):139-47.
PMID:
2001427
[PubMed - indexed for MEDLINE]
Related citations
77.
Modulative effects of cell adhesion peptide (Arg-Gly-Asp-Ser) on the
aggregation of stimulated platelets from ophthalmic patients.
Babizhayev MA, Mucha AI.
Clin Chim Acta. 1991 Feb 15;196(2-3):77-85.
PMID:
1827618
[PubMed - indexed for MEDLINE]
Related citations
78.
45. 45
Diamide-induced cross-linking of the lens water-soluble proteins as a
model of the early oxidative changes during senile cataract formation.
Babizhayev MA, Menshikova EV.
Mech Ageing Dev. 1990 Dec;56(3):199-208.
PMID:
2089197
[PubMed - indexed for MEDLINE]
Related citations
79.
Clinical, structural and molecular phototherapy effects of laser
irradiation on the trabecular meshwork of human glaucomatous eyes.
Babizhayev MA, Brodskaya MW, Mamedov NG, Batmanov YYe.
Graefes Arch Clin Exp Ophthalmol. 1990;228(1):90-100.
PMID:
2179062
[PubMed - indexed for MEDLINE]
Related citations
80.
Antioxidant activity of L-carnosine, a natural histidine-containing
dipeptide in crystalline lens.
Babizhayev MA.
Biochim Biophys Acta. 1989 Aug 22;1004(3):363-71.
PMID:
2758030
[PubMed - indexed for MEDLINE]
Related citations
46. 46
81.
Lipid peroxidation in open-angle glaucoma.
Babizhayev MA, Bunin AYa.
Acta Ophthalmol (Copenh). 1989 Aug;67(4):371-7.
PMID:
2801038
[PubMed - indexed for MEDLINE]
Related citations
82.
Lens opacity induced by lipid peroxidation products as a model of
cataract associated with retinal disease.
Babizhayev MA, Deyev AI.
Biochim Biophys Acta. 1989 Jul 17;1004(1):124-33.
PMID:
2742866
[PubMed - indexed for MEDLINE]
Related citations
83.
Accumulation of lipid peroxidation products in human cataracts.
Babizhayev MA.
Acta Ophthalmol (Copenh). 1989 Jun;67(3):281-7.
PMID:
2763816
[PubMed - indexed for MEDLINE]
Related citations
47. 47
84.
Morphometric evaluation of human lens opacification.
Babizhayev MA, Deyev AI, Derevyagin VI.
J Microsc. 1989 May;154(Pt 2):115-27.
PMID:
2746637
[PubMed - indexed for MEDLINE]
Related citations
85.
Fibronectin detection in drainage outflow system of human eyes in
ageing and progression of open-angle glaucoma.
Babizhayev MA, Brodskaya MW.
Mech Ageing Dev. 1989 Feb;47(2):145-57.
PMID:
2654504
[PubMed - indexed for MEDLINE]
Related citations
86.
Lipid fluorophores of the human crystalline lens with cataract.
Babizhayev MA.
Graefes Arch Clin Exp Ophthalmol. 1989;227(4):384-91.
PMID:
2777108
[PubMed - indexed for MEDLINE]
Related citations
48. 48
87.
The biphasic effect of calcium on lipid peroxidation.
Babizhayev MA.
Arch Biochem Biophys. 1988 Nov 1;266(2):446-51.
PMID:
3190239
[PubMed - indexed for MEDLINE]
Related citations
88.
Lipid peroxidation as a possible cause of cataract.
Babizhayev MA, Deyev AI, Linberg LF.
Mech Ageing Dev. 1988 Jul;44(1):69-89.
PMID:
3205065
[PubMed - indexed for MEDLINE]
Related citations
49. 49
Related citations 36
1.
[Stimulation of proliferation by carnosine: cellular and transcriptome
approaches].
Vishniakova KhS, Babizhaev MA, Aliper AM, Buzdin AA,
Kudriavtseva AV, Egorov EE.
Mol Biol (Mosk). 2014 Sep-Oct;48(5):824-33. Russian.
PMID:
25842868
Similar articles
2.
[Chaperone activity of alpha-crystallin for Ca-pump of the skeletal
muscle sarcoplasmic reticulum during stress and adaptation].
50. 50
Sazontova TG, Matskevich AA, Babizhaev MA, Arkhipenko IuV.
Biull Eksp Biol Med. 1999 Sep;128(9):279-82. Russian. No abstract
available.
PMID:
10560045
[PubMed - indexed for MEDLINE]
Related citations
3.
[Experimental morphological study of posttraumatic proliferative
vitreoretinopathy prevention by cell adhesion peptide Arg-Gly-Asp-Ser].
Khoroshilova-Maslova IP, Babizhaev MA, Kiseleva OA, Ilatovskaia
LV.
Vestn Oftalmol. 1997 Jul-Aug;113(4):27-31. Russian.
PMID:
9381638
[PubMed - indexed for MEDLINE]
Related citations
4.
[Lipoperoxidase activity of carnosine and carcinine].
Evstigneeva RP, Zheltukhina GA, Ageeva EA, Babizhaev MA.
Dokl Akad Nauk. 1993 Nov;333(1):104-6. Russian. No abstract
available.
PMID:
8298483
[PubMed - indexed for MEDLINE]
Related citations
51. 51
5.
[Potentiation by promethazine of hypotensive effects of adrenergic drugs
on intraocular pressure].
Ermakova VN, Babizhaev MA, Bunin AIa.
Biull Eksp Biol Med. 1991 Jun;111(6):627-9. Russian.
PMID:
1680016
[PubMed - indexed for MEDLINE]
Related citations
6.
[Diffusion properties of water in the human crystalline lens during
cataract development].
Babizhaev MA, Nikolaev GM, Goriachev SI, Dautova NR.
Biofizika. 1991 Mar-Apr;36(2):327-9. Russian.
PMID:
1892908
[PubMed - indexed for MEDLINE]
Related citations
7.
[Oligomerization of water soluble proteins of rabbit crystalline lens
under the action of diamide].
Babizhaev MA, Men'shikova EV, Ritov VB.
Biull Eksp Biol Med. 1990 Sep;110(9):269-71. Russian.
PMID:
2268711
[PubMed - indexed for MEDLINE]
Related citations
52. 52
8.
[Results of combined use of taufon and timolol in the treatment of
patients with open-angle glaucoma].
Bunin AIa, Ermakova VN, Babizhaev MA.
Vestn Oftalmol. 1990 Jul-Aug;106(4):9-11. Russian.
PMID:
2238339
[PubMed - indexed for MEDLINE]
Related citations
9.
[Extracellular glycoproteins of the ocular trabecular zone in patients
with primary open-angle glaucoma].
Babizhaev MA, Brodskaia MV, Batmanov IuE.
Vestn Oftalmol. 1990 Jan-Feb;106(1):51-6. Russian.
PMID:
2378039
[PubMed - indexed for MEDLINE]
Related citations
10.
[Photo damage to the eye in exposure to the radiation from a Nd:YAG
Q-switching laser: the physicochemical structural changes to the
crystalline lens and the vitreous body].
Stepanov AV, Babizhaev MA, Ivanov AN, Aĭtmagambetov MT, Deev
AI.
Vestn Oftalmol. 1990 Jan-Feb;106(1):31-5. Russian.
53. 53
PMID:
2378033
[PubMed - indexed for MEDLINE]
Related citations
11.
[Oxidation of pyridine nucleotides in injuries of the cornea].
Egorova EV, Babizhaev MA, Travkin AG, Tolchinskaia AI, Ioshin IE.
Vestn Oftalmol. 1989 May-Jun;105(3):43-6. Russian.
PMID:
2749972
[PubMed - indexed for MEDLINE]
Related citations
12.
[Morphometric analysis of lens opacification].
Babizhaev MA, Egorova ZB, Deev AI.
Vestn Oftalmol. 1989 Jan-Feb;105(1):43-6. Russian.
PMID:
2718310
[PubMed - indexed for MEDLINE]
Related citations
13.
[Molecular organization of protein-lipid components of the crystalline
lens].
Babizhaev MA.
54. 54
Biofizika. 1989 Jan-Feb;34(1):158-66. Review. Russian.
PMID:
2659091
[PubMed - indexed for MEDLINE]
Related citations
14.
[Spectral characteristics of intraocular lenses and injury to the retina
caused by visible light].
Egorova EV, Babizhaev MA, Ivanina TA, Zueva MV, Ioshin IE.
Biofizika. 1988 Nov-Dec;33(6):1035-40. Russian.
PMID:
3248216
[PubMed - indexed for MEDLINE]
Related citations
15.
[The participation of fibronectin in the mechanisms of dystrophic
changes in the ocular drainage system in open-angle glaucoma].
Brodskaia MV, Babizhaev MA, Ermolin GA.
Vestn Oftalmol. 1988 Nov-Dec;104(6):10-3. Russian. No abstract
available.
PMID:
3071887
[PubMed - indexed for MEDLINE]
Related citations
55. 55
16.
[The role of peroxidation in cosmetic ophthalmology].
Babizhaev MA, Egorova EV.
Vestn Oftalmol. 1988 Jul-Aug;104(4):55-8. Russian. No abstract
available.
PMID:
3218032
[PubMed - indexed for MEDLINE]
Related citations
17.
[Effect of carnosine on intraocular pressure].
Ermakova VN, Babizhaev MA, Bunin AIa.
Biull Eksp Biol Med. 1988 Apr;105(4):451-3. Russian.
PMID:
3359028
[PubMed - indexed for MEDLINE]
Related citations
18.
The antioxidative properties of carnosine, a natural histidine containing
dipeptide.
Boldyrev AA, Dupin AM, Bunin AYa, Babizhaev MA, Severin SE.
Biochem Int. 1987 Dec;15(6):1105-13. Review.
PMID:
3326603
[PubMed - indexed for MEDLINE]
56. 56
Related citations
19.
[Mechanisms of retinal damage in chloroquine retinopathy].
Ivanina TA, Lebedeva MN, Sakina NL, Babizhaev MA, Ermakova VN.
Biull Eksp Biol Med. 1987 Aug;104(8):180-3. Russian.
PMID:
3620676
[PubMed - indexed for MEDLINE]
Related citations
20.
[The chemical nature of the fluorescing products accumulating in the
lipids of the crystalline lenses of mice with hereditary cataract].
Shvedova AA, Platonov ES, Polianskiĭ NB, Babizhaev MA, Kagan VE.
Biull Eksp Biol Med. 1987 Mar;103(3):301-4. Russian.
PMID:
3828509
[PubMed - indexed for MEDLINE]
Related citations
21.
[Modification of membrane structures in cataract].
Babizhaev MA, Deev AI.
Vopr Med Khim. 1987 Mar-Apr;33(2):125-32. Russian.
PMID:
57. 57
3604133
[PubMed - indexed for MEDLINE
]
Related citations
22.
[Antioxidative enzyme activity and metabolism of peroxide compounds
in the crystalline lens during cataractogenesis].
Babizhaev M, Arkhipenko IuV, Kagan VE.
Biull Eksp Biol Med. 1987 Feb;103(2):143-6. Russian.
PMID:
3814788
[PubMed - indexed for MEDLINE]
Related citations
23.
[Photosensitized generation of singlet molecular oxygen by endogenous
substances of the eye lens].
Egorov SIu, Babizhaev MA, Krasnovskiĭ AA Jr, Shvedova AA.
Biofizika. 1987 Jan-Feb;32(1):169-71. Russian.
PMID:
3814638
[PubMed - indexed for MEDLINE]
Related citations
24.
[Cataract induction by products of lipid peroxidation].
Babizhaev MA, Brikman IV, Deev AI.
58. 58
Biofizika. 1987 Jan-Feb;32(1):121-4. Russian.
PMID:
3814630
[PubMed - indexed for MEDLINE]
Related citations
25.
[Crystalline lens induction of lipid peroxidation].
Babizhaev MA, Aĭtmagambetov MT, Deev AI, Vladimirov IuA.
Biull Eksp Biol Med. 1987 Jan;103(1):38-40. Russian.
PMID:
3801649
[PubMed - indexed for MEDLINE]
Related citations
26.
[Evidence of the oxidation of unsaturated fatty acids in cataracts].
Babizhaev MA, Linberg LF.
Biokhimiia. 1986 Oct;51(10):1702-7. Russian.
PMID:
3778973
[PubMed - indexed for MEDLINE]
Related citations
27.
[Decomposition of H2O2 by human cataractous lenses].
Babizhaev MA, Deev AI, Vladimirov IuA, Deeva IB.
59. 59
Biull Eksp Biol Med. 1986 Aug;102(8):158-60. Russian.
PMID:
3742026
[PubMed - indexed for MEDLINE]
Related citations
28.
[Lipid fluorophores of the crystalline lens in cataracts].
Babizhaev MA, Mirimskiĭ AS, Linberg LF.
Biofizika. 1986 Jul-Aug;31(4):681-6. Russian.
PMID:
3756234
[PubMed - indexed for MEDLINE]
Related citations
29.
[Mechanisms of the effects of Ca2+ ions on lipid peroxidation].
Savov VM, Babizhaev MA, Kagan VE.
Biull Eksp Biol Med. 1986 Jun;101(6):693-5. Russian.
PMID:
3015279
[PubMed - indexed for MEDLINE]
Related citations
30.
[Peroxidation crystalline lens damage--a possible cause of the
development of traumatic cataract].
60. 60
Babizhaev MA, Brikman IV, Deev AI, Vladimirov IuA, Bunin AIa.
Biull Eksp Biol Med. 1986 Apr;101(4):412-3. Russian. No abstract
available.
PMID:
3697487
[PubMed - indexed for MEDLINE
]
Related citations
31.
[Free radical oxidation of lipids and thiol groups in the formation of a
cataract].
Babizhaev MA, Deev AI.
Biofizika. 1986 Jan-Feb;31(1):109-14. Russian.
PMID:
3955083
[PubMed - indexed for MEDLINE]
Related citations
32.
[Accumulation of lipid peroxidation products in the human lens during
cataract maturation].
Babizhaev MA.
Vopr Med Khim. 1985 Nov-Dec;31(6):100-4. Russian.
PMID:
4090373
[PubMed - indexed for MEDLINE]
Related citations
61. 61
33.
[Accumulation of lipid peroxidation products in cataractous lenses].
Babizhaev MA, Shvedova AA, Arkhipenko IuV, Kagan VE.
Biull Eksp Biol Med. 1985 Sep;100(9):299-301. Russian.
PMID:
4041596
[PubMed - indexed for MEDLINE]
Related citations
34.
[NMR study of the state of water in the human lens during cataract
development].
Babizhaev MA, Deev AI, Nikolaev GM.
Biofizika. 1985 Jul-Aug;30(4):671-4. Russian.
PMID:
4052470
[PubMed - indexed for MEDLINE]
Related citations
35.
[Participation of the lipid peroxidation process in the destruction of the
drainage system of the eye in open-angle glaucoma].
Bunin AIa, Babizhaev MA, Suprun AV.
Vestn Oftalmol. 1985 Mar-Apr;101(2):13-6. Russian. No abstract
available.
PMID:
4002445
[PubMed - indexed for MEDLINE]
62. 62
Related citations
36.
[Formation of complexes of superoxide anion radicals with Ca++].
Babizhaev MA, Savoev VM, Kagan VE.
Biull Eksp Biol Med. 1983 Nov;96(11):47-8. Russian.
PMID:
6315105
[PubMed - indexed for MEDLINE]
Related citations
Other publications to Dr. Mark A. Babizhayev (listing available in
http://scholar.google.ru/scholar?hl=ru&q=Babizhayev)
Imidazole-containing peptide-based compounds in sight-threatening
age-related eye diseases
MA Babizhayev, A Kasus-Jacobi - Expert Review of …, 2009 -
ingentaconnect.com
... Financial & competing interests disclosure The biologically
significant applications of car- nosine
mimetics including those in ophthalmol- ogy were patented by Mark A
Babizhayev and the Alliance
Groups (WO 2004/028536 A1 ... Patents 10, 1045–1055 (2000). ... 38
Babizhayev MA ...
64. 64
Цитируется: 40 Похожие статьи Все версии статьи (3)
Цитировать
Imidazole-Containing Peptidomimetic NACA as a Potent Drug for the
Medicinal Treatment of Age-Related Cataract in Humans
To cite this article:
MARK A. BABIZHAYEV, VALENTINA N. YERMAKOVA, ANATOLY I.
DEYEV, and MARIE-CHRISTINE SEGUIN. Journal of Anti-Aging
Medicine. SPRING 2000, 3(1): 43-62. doi:10.1089/rej.1.2000.3.43.
[ЦИТИРОВАНИЕ] Ophthalmic pharmacology of N-acetylcarnosine
lubricant eye drops
MA Babizhayev - J Pharmacol Toxicol, 2006
Цитируется: 21 Похожие статьи Цитировать
ГОСТ Babizhayev M. A. Ophthalmic pharmacology of N-
acetylcarnosine lubricant eye drops //J Pharmacol Toxicol.
– 2006. – Т. 1. – №. 3. – С. 201-233.
MLA Babizhayev, Mark A. "Ophthalmic pharmacology of N-
acetylcarnosine lubricant eye drops." J Pharmacol Toxicol
1.3 (2006): 201-233.
APA Babizhayev, M. A. (2006). Ophthalmic pharmacology of N-
acetylcarnosine lubricant eye drops. J Pharmacol Toxicol,
1(3), 201-233.
65. 65
***
Issued Books and Chapters
http://www.amazon.com/Tragic-Accident-With-Princess-
Diana/dp/1617282707
66. 66
Tragic Accident With Princess Diana: The Effects of
Glare and Visual Disability on Driving
(Transportation Issues, Policies and R&D) [Paperback]
Mark A. Babizhayev
(Author)
15 new from $45.62 1 used from $47.96
Book Description
Publication Date: May 30, 2011 | ISBN-10: 1617282707 | ISBN-13: 978-1617282706
This book presents an investigation into some of the most common causes that experts
believe are responsible for traffic accidents and vehicle crashes. Using the death of Princess
Diana and Dodi Fayed in a car accident as the main point of reference, the book explores
various factors which could have impacted upon their death, and that of many other people.
Many incidents of mortality on the roads are due to the inadequate provision that is made in
the country regarding examination of the visual performance of drivers. Especially when
driving at night, even drivers with a full visual function reach their psychological limit, with
the glare of headlights and street lamps also serving as a considerable impediment. This
book emphasises that regular visual testing of a driver with glare source-based stimuli and
application of lenses equipped with the anti-reflection coatings, traffic accidents and deaths
could be considerably reduced.
Product Details
Series: Transportation Issues, Policies and R&D
Paperback: 85 pages
Publisher: Nova Science Publishers (May 30, 2011)
Language: English
ISBN-10: 1617282707
ISBN-13: 978-1617282706
Product Dimensions: 5.5 x 8.5 inches
Shipping Weight: 5 ounces
69. 69
Respiratory Diseases: Causes, Treatment and Prevention
$95.00
Editors: Luke Wagener and Noah Barfield
https://www.novapublishers.com/catalog/product_info.php?products_id
=30208
Series:
Public Health in the 21st Century
Binding: ebook
Pub. Date: 2012 - 1st Quarter
Book Description:
Respiratory diseases encompass pathological conditions affecting the
organs and tissues that make gas exchange possible in higher organisms,
and includes conditions of the upper respiratory tract, trachea, bronchi,
bronchioles, alveoli, pleura and pleural cavity, and the nerves and muscles
of breathing. Respiratory diseases range from mild and self-limiting, such
as the common cold, to life-threatening entities like bacterial pneumonia,
pulmonary embolism, and lung cancer. The authors of this book present
current research in the causes, treatment and prevention of respiratory
diseases. Topics include dietary prevention of chronic obstructive
pulmonary disease; effects of air pollution on the human respiratory
system; immunotherapy in respiratory allergy and the lung as a target
70. 70
organ for Type 2 diabetes complications. (Imprint: Nova Biomedical)
Table of Contents:
Preface
Telomere Attrition and Heightened Oxidative Stress Induced by
Cigarette Smoking: Developed Nutrition Formulas of Non-Hydrolized
Carnosine and Carcinine Supplements Offer Great Opportunities for
Innovative Therapeutic Strategies to Attenuate Naturally Accelerated
Aging and the Risk of Respiratory Disease Associated with Smoking:
Can We Have Safer Cigarettes?
(Mark A. Babizhayev, Yegor E. Yegorov, Innovative Vision Products, Inc.,
Delaware, USA, and others)
In: Aging: Mental Aspects, Social Welfare and Health 2011
Nova Science Publishers Inc., Chapter 2 pp.49-90
$95.00
Editors: Jim P. Heckles and Laura M. Bergin
Book Description:
In this book, the authors present topical research in the study of the
mental aspects, social welfare and health of the aging population.
Topics discussed include assessing the quality of life of the elderly
population; age-related ophthalmic disease; assessment of the at-risk
older driver; social services for the elderly in Hong Kong; increased
lifespan for people with intellectual disabilities and locomotor
disability in the aged. (Imprint: Nova)
Click to enlarge
72. 72
Provides comprehensive discussion of cataracts from
etiology and prevention, pediatrics, diabetic retinopathy and
more
Explores timely, relevant topics like pediatric cataracts and
stem cells in corneal disease