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Case Report
By Sameep Adhikari
August 30,
2015
Case report1
Case History
Name- xxxx
Age/sex- 41 yrs/ F
Occupation- Housewife
Complaints-
RE- c/o unilateral drooping of upper eyelid
that varies during the day and aggravated after use
of Botulinum toxin injection x 4 months
LE- No c/o drooping of eyelid
BE- c/o gradual decrease in distance vision x
2 months
RE- No other specific ocular complaints
August 30, 2015
Case report
2
Previous ocular history-
No h/o glasses wear
No h/o surgery and trauma
General health-
No h/o DM and HTN
h/o botulinum toxin injection used for cosmetic
purpose
Family history-
Not contributory
Recent investigation-
Nil
Current treatment-
Nil
Allergy-
Not aware of any
August 30, 2015
Case report
3
Ocular examination
 Visual Acuity-
Distance visual acuity with snellen chart (U/A)
RE- 6/9 PH 6/6p (upper eyelid uplifted)
LE- 6/9 PH 6/6
Near visual acuity with continuous text chart @
38 cms
RE- N6
LE- N6
August 30, 2015
Case report
4
 Refraction-
 Objective refraction
RE- +0.25 DS/ -1.00 DC x 100
LE- ±/ -0.50 DC x 90
 Subjective refraction
RE- ±/ -0.75 DC x 100 (6/6)
LE- ±/ -0.50DC x 80 (6/6)
 Duochrome-
RE- Balanced
LE- Balanced
 JCC-
BE- JCC refined
August 30, 2015
Case report
5
 Keratometer
RE- 45.00D@V [7.5mm]
44.00D@H[7.67mm]
LE- 45.5D@V[7.41mm]
45.00D@H[7.5mm]
 Extra ocular motility-
0 0 0 0 0 0
0 0 0 0
0 0 0 0
0 0
RE- SAFE LE- SAFE
August 30, 2015
Case report
6
 Hirschberg test-
ortho
 Pupils-
RE- PERRLA
LE- PERRLA
No RAPD
 Colour vision with Ishihara plates @75 cms
RE- 25/25 (correct response)
LE- 25/25 (correct response)
August 30, 2015
Case report
7
 Confrontation-
RE-
within normal limits
LE-
within normal limits
August 30, 2015
Case report
8
Ptosis evaluation
 Head posture
Normal
 Palpebral fissure height
RE- 7.5 mm
LE- 11 mm
 Marginal reflex distance(MRD)-1
RE- 2.5 mm
LE- 5.5 mm
August 30, 2015
Case report
9
 Marginal reflex distance(MRD)-2
RE- 5 mm
LE- 5.5 mm
 Margin crease distance (MCD)-
RE- 8 mm
LE- 8.5 mm
 Levator function-
RE- 11 mm
LE- 14 mm
August 30, 2015
Case report
10
 Margin limbal distance-
RE- 8 mm
LE- 10 mm
 Bell’s phenomenon-
RE- present
LE- present
 Corneal sensitivity-
RE- present
LE- present
August 30, 2015
Case report
11
 Fatigue test-
RE- positive
LE- positive
 Tensilion test-
RE- absent
LE- absent
 Marcus Gunn jaw winking phenomenon-
RE- absent
LE- absent
August 30, 2015
Case report
12
 Frontalis overaction
RE- Absent
LE- Absent
 Cogan lid twitch test-
RE- Negative
LE- Negative
 10% phenylephrine test:
RE- improves by 2mm
LE- same as before
August 30, 2015
Case report
13
 Slit lamp examination
ptosis
normal
Conjunctiva-
normal
Cornea-
normal
Pupils- RTL
Lens- normal Lens- normal
RE LE
August 30, 2015
Case report
14
 Fundus examination
Retina- ON
FR+
Cdr-
normal
RE LE
August 30, 2015
Case report
15
 Diagnosis-
mild ptosis
 Advice-
ptosis crutch
follow up after 6 months
August 30, 2015
Case report
16
Ptosis
 Abnormal drooping of upper eyelid
 Classification of ptosis
 Congenital ptosis
 Acquired ptosis
a. Myogenic ptosis- caused by
myopathy of levator function or impaired
transmission of impulses at neuromuscular
junction
 Seen in case of myasthenia gravis, myotonic
dystrophy and LPS muscle trauma
August 30, 2015
Case report
17
b. Neurogenic ptosis- caused by
innervational defect such as third nerve palsy or
Horner’s syndrome
c. Aponeurotic ptosis- caused by defect
in levator aponeurosis such as senile or postoperative
cases
d. Mechanical ptosis- caused due to
excessive weight on upper eyelid like as in eyelid
tumours, scars and chalazion
August 30, 2015
Case report
18
Clinical manifestation
 Symptoms
 Asymptomatic if pupil is not covered
 Visual disturbance if pupil is covered
 Cosmetic disfigurement
 Diplopia
 Abnormal head posture and head tilt
August 30, 2015
Case report
19
 Signs
 Narrow palpebral fissure height
 Absence of upper eyelid crease in case of
congenital ptosis
 Frontalis overaction
 Backward head tilt
 Signs related to underlying cause
August 30, 2015
Case report
20
Clinical evaluation of ptosis
 History taking-
 Age of onset
 Aggravating or alleviating factors
 Variation in amount of ptosis during the
day
 Associated with diplopia, abnormal head
posture
August 30, 2015
Case report
21
 Palpebral fissure height-
 Margin reflex distance(MRD)-1
August 30, 2015
Case report
22
 Margin reflex distance(MRD)-2
 Distance between lower lid margin and pupillary
reflex
 Margin crease distance-
August 30, 2015
Case report
23
 Levator function-
 Margin limbal distance-
 Distance from middle of upper eyelid to inferior
limbus
August 30, 2015
Case report
24
 Bell’s phenomenon-
 Corneal sensitivity-
August 30, 2015
Case report
25
 Frontalis overaction
 Marcus-Gunn jaw winking phenomenon
August 30, 2015
Case report
26
Normal values
Tests done for ptosis
evaluation
Normal values
Palpebral fissure height 7-10mm(male)
8-12mm(female)
Margin reflex
distance(MRD)1
4-5mm
Margin reflex
distance(MRD)2
>5mm
Lid crease height 5-7mm(male)
8-10mm(female)
Levator function 13-17mm
Margin limbal distance 9mm
Bell’s phenomenon Upward rotation of eyeball
with closure of eyelid
August 30, 2015
Case report
27
 Tensilion test-
1 mg of neostigmine is injected in a
patient.
In case of Myasthania gravis, ptosis
improves in 5-10 minutes
 Cogan lid twitch test-
Patient is asked to look downwards and
then in primary position quickly. The upper eyelid
retracts and then droops slowly to ptotic condition.
Positive result suggests of Myasthania
gravis in patient.
August 30, 2015
Case report
28
Pseudoptosis
Right pseudoptosis due to
artificial eye
Brow ptosis
August 30, 2015
Case report
29
Dermatochalasis
Left pseudoptosis due to
contralateral eyelid
retraction
August 30, 2015
Case report
30
Management
 Ptosis crutches- to hold the upper eyelid
to avoid eyelid to cover the pupil
 Treat the underlying causes
 Surgery –
 Tarso-conjunctivo-Mullerctomy(Fasanella-
servat operation)
 Levator resection
 Frontalis sling operation
August 30, 2015
Case report
31
Thank you…
August 30, 2015
Case report
32

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Ptosis case report

  • 1. Case Report By Sameep Adhikari August 30, 2015 Case report1
  • 2. Case History Name- xxxx Age/sex- 41 yrs/ F Occupation- Housewife Complaints- RE- c/o unilateral drooping of upper eyelid that varies during the day and aggravated after use of Botulinum toxin injection x 4 months LE- No c/o drooping of eyelid BE- c/o gradual decrease in distance vision x 2 months RE- No other specific ocular complaints August 30, 2015 Case report 2
  • 3. Previous ocular history- No h/o glasses wear No h/o surgery and trauma General health- No h/o DM and HTN h/o botulinum toxin injection used for cosmetic purpose Family history- Not contributory Recent investigation- Nil Current treatment- Nil Allergy- Not aware of any August 30, 2015 Case report 3
  • 4. Ocular examination  Visual Acuity- Distance visual acuity with snellen chart (U/A) RE- 6/9 PH 6/6p (upper eyelid uplifted) LE- 6/9 PH 6/6 Near visual acuity with continuous text chart @ 38 cms RE- N6 LE- N6 August 30, 2015 Case report 4
  • 5.  Refraction-  Objective refraction RE- +0.25 DS/ -1.00 DC x 100 LE- ±/ -0.50 DC x 90  Subjective refraction RE- ±/ -0.75 DC x 100 (6/6) LE- ±/ -0.50DC x 80 (6/6)  Duochrome- RE- Balanced LE- Balanced  JCC- BE- JCC refined August 30, 2015 Case report 5
  • 6.  Keratometer RE- 45.00D@V [7.5mm] 44.00D@H[7.67mm] LE- 45.5D@V[7.41mm] 45.00D@H[7.5mm]  Extra ocular motility- 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RE- SAFE LE- SAFE August 30, 2015 Case report 6
  • 7.  Hirschberg test- ortho  Pupils- RE- PERRLA LE- PERRLA No RAPD  Colour vision with Ishihara plates @75 cms RE- 25/25 (correct response) LE- 25/25 (correct response) August 30, 2015 Case report 7
  • 8.  Confrontation- RE- within normal limits LE- within normal limits August 30, 2015 Case report 8
  • 9. Ptosis evaluation  Head posture Normal  Palpebral fissure height RE- 7.5 mm LE- 11 mm  Marginal reflex distance(MRD)-1 RE- 2.5 mm LE- 5.5 mm August 30, 2015 Case report 9
  • 10.  Marginal reflex distance(MRD)-2 RE- 5 mm LE- 5.5 mm  Margin crease distance (MCD)- RE- 8 mm LE- 8.5 mm  Levator function- RE- 11 mm LE- 14 mm August 30, 2015 Case report 10
  • 11.  Margin limbal distance- RE- 8 mm LE- 10 mm  Bell’s phenomenon- RE- present LE- present  Corneal sensitivity- RE- present LE- present August 30, 2015 Case report 11
  • 12.  Fatigue test- RE- positive LE- positive  Tensilion test- RE- absent LE- absent  Marcus Gunn jaw winking phenomenon- RE- absent LE- absent August 30, 2015 Case report 12
  • 13.  Frontalis overaction RE- Absent LE- Absent  Cogan lid twitch test- RE- Negative LE- Negative  10% phenylephrine test: RE- improves by 2mm LE- same as before August 30, 2015 Case report 13
  • 14.  Slit lamp examination ptosis normal Conjunctiva- normal Cornea- normal Pupils- RTL Lens- normal Lens- normal RE LE August 30, 2015 Case report 14
  • 15.  Fundus examination Retina- ON FR+ Cdr- normal RE LE August 30, 2015 Case report 15
  • 16.  Diagnosis- mild ptosis  Advice- ptosis crutch follow up after 6 months August 30, 2015 Case report 16
  • 17. Ptosis  Abnormal drooping of upper eyelid  Classification of ptosis  Congenital ptosis  Acquired ptosis a. Myogenic ptosis- caused by myopathy of levator function or impaired transmission of impulses at neuromuscular junction  Seen in case of myasthenia gravis, myotonic dystrophy and LPS muscle trauma August 30, 2015 Case report 17
  • 18. b. Neurogenic ptosis- caused by innervational defect such as third nerve palsy or Horner’s syndrome c. Aponeurotic ptosis- caused by defect in levator aponeurosis such as senile or postoperative cases d. Mechanical ptosis- caused due to excessive weight on upper eyelid like as in eyelid tumours, scars and chalazion August 30, 2015 Case report 18
  • 19. Clinical manifestation  Symptoms  Asymptomatic if pupil is not covered  Visual disturbance if pupil is covered  Cosmetic disfigurement  Diplopia  Abnormal head posture and head tilt August 30, 2015 Case report 19
  • 20.  Signs  Narrow palpebral fissure height  Absence of upper eyelid crease in case of congenital ptosis  Frontalis overaction  Backward head tilt  Signs related to underlying cause August 30, 2015 Case report 20
  • 21. Clinical evaluation of ptosis  History taking-  Age of onset  Aggravating or alleviating factors  Variation in amount of ptosis during the day  Associated with diplopia, abnormal head posture August 30, 2015 Case report 21
  • 22.  Palpebral fissure height-  Margin reflex distance(MRD)-1 August 30, 2015 Case report 22
  • 23.  Margin reflex distance(MRD)-2  Distance between lower lid margin and pupillary reflex  Margin crease distance- August 30, 2015 Case report 23
  • 24.  Levator function-  Margin limbal distance-  Distance from middle of upper eyelid to inferior limbus August 30, 2015 Case report 24
  • 25.  Bell’s phenomenon-  Corneal sensitivity- August 30, 2015 Case report 25
  • 26.  Frontalis overaction  Marcus-Gunn jaw winking phenomenon August 30, 2015 Case report 26
  • 27. Normal values Tests done for ptosis evaluation Normal values Palpebral fissure height 7-10mm(male) 8-12mm(female) Margin reflex distance(MRD)1 4-5mm Margin reflex distance(MRD)2 >5mm Lid crease height 5-7mm(male) 8-10mm(female) Levator function 13-17mm Margin limbal distance 9mm Bell’s phenomenon Upward rotation of eyeball with closure of eyelid August 30, 2015 Case report 27
  • 28.  Tensilion test- 1 mg of neostigmine is injected in a patient. In case of Myasthania gravis, ptosis improves in 5-10 minutes  Cogan lid twitch test- Patient is asked to look downwards and then in primary position quickly. The upper eyelid retracts and then droops slowly to ptotic condition. Positive result suggests of Myasthania gravis in patient. August 30, 2015 Case report 28
  • 29. Pseudoptosis Right pseudoptosis due to artificial eye Brow ptosis August 30, 2015 Case report 29
  • 30. Dermatochalasis Left pseudoptosis due to contralateral eyelid retraction August 30, 2015 Case report 30
  • 31. Management  Ptosis crutches- to hold the upper eyelid to avoid eyelid to cover the pupil  Treat the underlying causes  Surgery –  Tarso-conjunctivo-Mullerctomy(Fasanella- servat operation)  Levator resection  Frontalis sling operation August 30, 2015 Case report 31
  • 32. Thank you… August 30, 2015 Case report 32