This document provides guidelines for treating neuropathic conditions, including choosing proper footwear and orthotics, using total contact casting, offloading ulcers, proper wound and skin care, callus management, and patient education. Key recommendations are to offload pressure and shear forces through specialized footwear, casting, or ulcer offloading in order to prevent tissue damage and promote wound healing. Patient education focuses on proper foot inspection and skin care to compensate for potential loss of sensation.