- Synvisc One is a better option for knee osteoarthritis (OA) patients who have mild pain not adequately managed by oral painkillers, do not have severe joint degeneration requiring surgery, and want to delay total knee replacement surgery. - Combining Synvisc One with mild painkillers can better manage OA than stronger NSAIDs, which risk stomach ulcers and renal damage with chronic use. Synvisc One also helps maintain joint status quo, unlike oral drugs that do not stop disease progression. - A patient support program for Synvisc One should provide information on OA and the treatment, reminders for medication timing, assistance with costs, and connect patients to local doctors and

1. Why is Synvisc One a better option to
knee OA patients?
– Oral painkillers not showing adequate results and knee not
degenerated enough for surgery.
– Chronic use of NSAIDs can cause stomach ulcers as well as renal
damage.
– Combination of mild painkillers and synvisc one can better
manage OA than stronger NSAIDs.
– Want to delay TKRS (total knee replacement surgery). They can
be those who-
1. Are not more than 55 years.
2. Do not have time for surgery
– Helps maintaining status quo for OA, whereas oral drugs do
not stop the progression of the disease.
– Have other significant co morbidities ,so surgery not advisable.

2. Why should the doctor start early?
• OA is a lifelong disorder which may or may not worsen
with age ,depending on how OA was managed at
earlier stages.
• Various studies show that patients on long term
NSAIDs use may develop gastrointestinal and renal
problems.
• Early usage of viscosupplements can stall the
degradation of joint and further damage to cartilage
and ligaments can be stopped.
• Synvisc one can be used as many times as is required
,so early start can be recommended.
• Patient is free from the regular rigour of popping a pill.

3. Patient support
program

4. What is a patient support program?
• It’s a holistic program making available various
facilities to the patients which helps the
patient in managing their disease in a better
way.
• From what the disease is about to how a
normal life can be lead ,everything is covered
in a good patient support program.
• Some examples of good patient support
program are:

5. Cancer patient support program
• CPSP Services
• The Cancer Patient Support Program (CPSP) offers a number of
services to help patients through what can be a very difficult time.
• One-to-one patient orientation
• Individual counseling for patients and family members
• Support meetings
• Educational programs
• Hospitality and refreshments in Outpatient Clinics
• Resource Center
• Appearance consultation for treatment-related side effects
• Free wigs and turbans

6. BETAPLUS Patient Support Program
Started by bayer it gives the patient every
information that he needs to know about
Multiple Sclerosis and usage of the drug. Email
and call facility for timely medicine intake.

7. Humira patient support program
• By abbott laboratories
• Talks about usage, financial aid ,email and call
reminders to follow dosage regimen.
• Also shows videos on usage and disposal of
the injection.

8. Elements of a good patient support
program
• Should have information about the disease.
• Symptom check tests should be available.
• Should have latest studies and articles on management of disease.
• One to one patient meetings arranging facilities should be there.
• Patient community acting as a support group should be there.
• Address of various hospitals and HCP with their contact no can also be
made available.
• Should have a good DBMS where the progress of disease in a patient by the
patient can be monitored.
• DBMS should also be used by the company to send timely reminders via e-
mails and calls to the patients about their next visit to doctor or dosage
reminders.
• Should also have 24 hour call support/helpline where patients and doctors
alike can clarify their doubts
• Should suggest how the cost for the therapy can be covered . Give
assistance in helping the patient go for medical insurance
• Regular seminars and educational meetings can be arranged for
comprehensive understanding of the disease by patients.

9. Benefits of patient support program
• Reducing costs
• Increasing adherence
• Managing chronic conditions
• Driving retention
• Promoting wellness
• Maximizing call center resources

10. Should Synvisc One have a PSP?
YES ,synvisc one should definitely have a psp. The website has patient
information corner about the disease and synvisc one .
Some of the things not present are:
• Direct line where patients can clarify their doubts.
• No list of local doctors(INDIAN) provided who can be approached for
synvisc one treatment.
• Patient support community shall also be started where experiences can be
shared.
• As it is a costly treatment, assistance and guidance to get medical
insurance for the treatment must be provided.
• Due to long duration between two shots of synvisc one ,reminder through
calls and e-mails shall be made to the users.
• For the untapped patient who is suffering from OA, information shall be
made available through mass media about alternative ways to manage
OA. A patient armed with info about synvisc one can make the doctor try
it on him/her.
• Other then the above ,all the elements of a good patient support program
should be considered