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CD4 structure and post-translational modifications

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Project: CD4 1 Accession # M12807 2. Brady RL, Dodson EJ, Dodson GG, Lange G, Davis SJ, Williams AF, Barclay AN. Crystal structure of domains 3 and 4 of rat CD4: relation to the NH2-terminal domains. Science. 1993 May 14;260(5110):979-83 2. C. Pitcher, S. Honing, A. Fingerhut, K. Bowers, M. Marsh Mol. Biol. Cell 10, 677 (1999). 16 84 130 159 300 345 271 370 396 303 N-linked Glycosylation sites S S S S S S D4 D3 D2 D1 433 Serine 408 Phos, lck dissociation and internalization2 Cysteine 420/22 Lck binding CD4 Cysteine 396/99 Palmitoylation/Lipid Raft Association1 2. R. Fragoso, D. Ren, X, Zhang, M. Wei-Chih Su, S.J. Burakoff, Y-J Jin J. Immunol 170, 913 (2003).

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CD4 structure and post-translational modifications

  • 1. Project: CD4 1 Accession # M12807 2. Brady RL, Dodson EJ, Dodson GG, Lange G, Davis SJ, Williams AF, Barclay AN. Crystal structure of domains 3 and 4 of rat CD4: relation to the NH2-terminal domains. Science. 1993 May 14;260(5110):979-83 2. C. Pitcher, S. Honing, A. Fingerhut, K. Bowers, M. Marsh Mol. Biol. Cell 10, 677 (1999). 16 84 130 159 300 345 271 370 396 303 N-linked Glycosylation sites S S S S S S D4 D3 D2 D1 433 Serine 408 Phos, lck dissociation and internalization2 Cysteine 420/22 Lck binding CD4 Cysteine 396/99 Palmitoylation/Lipid Raft Association1 2. R. Fragoso, D. Ren, X, Zhang, M. Wei-Chih Su, S.J. Burakoff, Y-J Jin J. Immunol 170, 913 (2003).