This document lists 10 research articles published between 2009-2013 that describe advances in the development and application of TALENs (Transcription Activator-Like Effector Nucleases), a type of engineered nuclease used for genome editing. Key findings include the development of new assembly methods and techniques for customizing TALENs to target specific DNA sequences, using TALENs to successfully edit genes in various organisms like mice, livestock and frogs, and determining preferences of different TAL effector repeat variable di-residues (RVDs) when binding DNA.

1.  1. Engler C, Gruetzner R, Kandzia R and Marillonnet S (2009) Golden gate
shuffling:a one-pot DNA shuffling method based on type IIs restriction
enzymes. PLoS One 4 :e5553
 2. Cermak T, Doyle EL, Christian M, Wang L, Zhang Y, Schmidt C, Baller
JA, Somia NV, Bogdanove AJ, Voytas DF (2011) Efficient design and
assembly of custom TALEN and other TAL effector-based constructs for
DNA targeting. Nucleic acid research 39: e82
 3.Christian ML, Demorest ZL, Starker CG, Osborn MJ, Nyquist MD, et al.
(2012) Targeting G with TAL Effectors: A Comparison of Activities of TALENs
Constructed with NN and NK Repeat Variable Di-Residues. PLoS ONE 7(9):
e45383. doi:10.1371/journal.pone.0045383
 4. Streubel J, Blücher C, Landgraf A ,Boch J (2012) TAL effector RVD
specificities and efficiencies. Nature Biotechnology 30 :593–595
 5. Schmid-Burgk JL, Schmidt T, Kaiser V, Höning K, Hornung V (2013) A
ligation-independent cloning technique for high-throughput assembly of
transcription activator–like effector genes. Nat Biotechnol 31(1):76-81

2.  6. DE lange O, Schreiber T ,Schandry N, Radeck J, Braun KH, Koszinowski
J ,Heuer H,Straub A, Lahaye T(2013)Breaking the DNA binding code
Ralstonia solanacearum TAL effectors provide new possibilities ti generate
plant resistance genes against bacterial wilt disease. New phytologist ,doi
10.111/nph.12324.
 7. Qiu Z, Liu M, Chen Z, shao Y, Pan H, Wei G, Yu C, Zhang L, Li X, Wang
P, Fan H-Y, Du B, Liu B, Liu M, Li D (2013)high efficiency and heritable
genes targeting in mouse by transcription activator like effector nucleases.
Nucleic acid Research, doi :10.10931/nar/gkt258.
 8. Carlson D F,Tan W, Lillico S G,stverakova D, Proudfoot C, Christian M,
Voytas D F, Long CR,Whitelaw C B A, Fahrenkrug S C (2012)Efficient
TALEN-mediated gene knockout in livestock, PNAS :vol 109 .
 9. Wang H, Hu Y-C, Markoulaki S, Welstead G G, Cheng A W, Shivalila C
S,Pyntikova T, Dadon D B, Voytas D F, Bogdanove A J, Page D C,
Jaenisch R(2013) Talen-mediated editing of the mouse Y chromosome.
Nature Biotechnology,doi:10.1038/nbt2595

3.  10. Suzuki K-I T, Isoyama Y, Kashiwagi K,Sakuma T, Ochiai H, Sakamoto
N,Furuno N, Kashiwagi A, Yamamoto T(2013)High efficiency TALENs
enables F0 functional analysis by targeted gene disruption in xenopus
laevis embryos. Biology open,doi:10.1242/bio20133855.