This document provides an overview of the 21st annual Oldtime Baseball Game which raises money for ALS research. Several notable former professional and college baseball players will participate, including Lou Merloni, Mike Timlin, and Matt Antonelli from the MLB as well as Pete Frates who was diagnosed with ALS and has advocated for research. The game aims to honor Pete Frates and others impacted by ALS while celebrating baseball and raising funds and awareness for treatment.