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Problem II - Control of gastric acidity. 1. What is the trigger to target the intracellular vesicles
expressing the H / K pump to the plasma membrane? 2. What is the type of transport system
represented by the H / K pump? 3. Explain the rational of accumulating H + in the stomach
cavity in the context of the trigger identified in question 1. 4. Identify the 3 mechanisms by
which one can reduce the amount of H + secreted in the stomach cavity. 5. In the case of
someone who has chronic elevated stomach acidity, why would you prefer inhibiting the H / K
pump than using acid - neutralizing agents?

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  • 1. Problem II - Control of gastric acidity. 1. What is the trigger to target the intracellular vesicles expressing the H / K pump to the plasma membrane? 2. What is the type of transport system represented by the H / K pump? 3. Explain the rational of accumulating H + in the stomach cavity in the context of the trigger identified in question 1. 4. Identify the 3 mechanisms by which one can reduce the amount of H + secreted in the stomach cavity. 5. In the case of someone who has chronic elevated stomach acidity, why would you prefer inhibiting the H / K pump than using acid - neutralizing agents?