Privacy for the People | HCIC 2023

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The document discusses the benefits of exercise for mental health. Regular physical activity can help reduce anxiety and depression and improve mood and cognitive functioning. Exercise has also been shown to boost self-esteem and can serve as a healthy way to manage stress.

Science

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We characterize the earliest galaxy population in the JADES Origins Field (JOF), the deepest imaging field observed with JWST. We make use of the ancillary Hubble optical images (5 filters spanning 0.4−0.9µm) and novel JWST images with 14 filters spanning 0.8−5µm, including 7 mediumband filters, and reaching total exposure times of up to 46 hours per filter. We combine all our data at > 2.3µm to construct an ultradeep image, reaching as deep as ≈ 31.4 AB mag in the stack and 30.3-31.0 AB mag (5σ, r = 0.1” circular aperture) in individual filters. We measure photometric redshifts and use robust selection criteria to identify a sample of eight galaxy candidates at redshifts z = 11.5 − 15. These objects show compact half-light radii of R1/2 ∼ 50 − 200pc, stellar masses of M⋆ ∼ 107−108M⊙, and star-formation rates of SFR ∼ 0.1−1 M⊙ yr−1 . Our search finds no candidates at 15 < z < 20, placing upper limits at these redshifts. We develop a forward modeling approach to infer the properties of the evolving luminosity function without binning in redshift or luminosity that marginalizes over the photometric redshift uncertainty of our candidate galaxies and incorporates the impact of non-detections. We find a z = 12 luminosity function in good agreement with prior results, and that the luminosity function normalization and UV luminosity density decline by a factor of ∼ 2.5 from z = 12 to z = 14. We discuss the possible implications of our results in the context of theoretical models for evolution of the dark matter halo mass function.

Earliest Galaxies in the JADES Origins Field: Luminosity Function and Cosmic ...

Sérgio Sacani

Shuaib Y-basedComprehensive mahmudj.pptx

MdAbuRayhan16

PESTS OF SUGARCANE - BORERS BORERS 1. Early shoot borer, Chilo infuscatellus, Crambidae, Lepidoptera Symptom of damage: Deadheart in 1-3 month old crop, which can be easily pulled out, rotten portion of the straw coloured dead-heart emits an offensive odour. A number of bore holes at the base of the shoot just above the ground level. Nature of damage: Caterpillar bores into the central shoot and feeds on the internal tissue. This cause interference in the translocation of plant sap and damage the sugar storing tissues. Egg: Flat-scale like eggs are laid in 3-5 rows on the lower surface of leaves in masses of 4-100. The masses are slightly overlapping like tiles. Larva: Larva is dirty white with five dark violet longitudinal stripes and dark brown head. Pupa: Pupation takes place within the tunnel. Caterpillar before pupating makes a large exit hole in the stem and blocks the opening with silken discs. Adult: Pale greyish brown moth with black dots near the costal margin of the forewings and with white hindwings. 2. Internode borer, Chilo sacchariphagus indicus, Crambidae, Lepidoptera Symptom of damage: Internodes constricted and shortened, with a number of boreholes and fresh excreta in the nodal region. Affected tissues reddened. Nature of damage: Caterpillars attack sugarcane plants after 3 months of planting. They bore into the canes near the nodes; entry holes are plugged with excreta. Entry is generally confined to the first five internodes. Egg: Scale-like white eggs are laid by female moths in batches of 9-11, near the midribs, on leaf sheaths or on stem. Larva: White larva with four violet longitudinal stripes and light brown head. Pupa: Pupation takes place in semi-dried leaf sheath. Adult: Pale brown with white hind wings. 3. Top borer, Scirpophaga excerptalis, Pyralidae, Lepidoptera Symptom of damage: Deadheart in grownup canes, which cannot be easily pulled; deadheart reddish brown in colour; parallel row of shot holes in the emerging leaves and red tunnels in the midribs of leaves; bunchy tip due to the growth of side shoots. Nature of damage: Caterpillars are mainly found in the apical portion of the canes, boring through the growing point and down the upper joints until it reaches the sappy portion of the stem, there it feeds on the tissues and destroys the cane. They also bore into the unfolded leaves preferably into the midrib, mining its way to the base. Egg: Eggs are laid on the lower surface of top leaves in clusters particularly near midribs. The clusters are covered with buff coloured hairs. Larva :Smooth, white or cream coloured with a red coloured mid-dorsal line and yellow head. Pupa: Pupation takes place within the larval tunnel in a chamber with an exit hole constructed by the caterpillar. Adult: White coloured moth (with a buff coloured anal tuft in the abdominal tip of female).

Pests of sugarcane_Binomics_IPM_Dr.UPR.pdf

PirithiRaju

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Introduction: RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression. It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences. dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants. This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes. What are small ncRNAs? micro RNA (miRNA) short interfering RNA (siRNA) Properties of small non-coding RNA: Involved in silencing mRNA transcripts. Called “small” because they are usually only about 21-24 nucleotides long. Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered). Silence an mRNA by base pairing with some sequence on the mRNA. Discovery of siRNA? The first small RNA: In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the development of the worm C. elegans. Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14. Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions. Types of RNAi ( non coding RNA) MiRNA Length (23-25 nt) Trans acting Binds with target MRNA in mismatch Translation inhibition Si RNA Length 21 nt. Cis acting Bind with target Mrna in perfect complementary sequence Piwi-RNA Length ; 25 to 36 nt. Expressed in Germ Cells Regulates trnasposomes activity MECHANISM OF RNAI: First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces. Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands. The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it. THE RISC COMPLEX: RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA Unwinding of double stranded Si RNA by ATP independent Helicase Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA. DICER: endonuclease (RNase Family III) Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC) One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute ARGONAUTE PROTEIN : 1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA 2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity. MiRNA: The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .

RNA INTERFERENCE: UNRAVELING GENETIC SILENCING

AADYARAJPANDEY1

The increased availability of biomedical data, particularly in the public domain, offers the opportunity to better understand human health and to develop effective therapeutics for a wide range of unmet medical needs. However, data scientists remain stymied by the fact that data remain hard to find and to productively reuse because data and their metadata i) are wholly inaccessible, ii) are in non-standard or incompatible representations, iii) do not conform to community standards, and iv) have unclear or highly restricted terms and conditions that preclude legitimate reuse. These limitations require a rethink on data can be made machine and AI-ready - the key motivation behind the FAIR Guiding Principles. Concurrently, while recent efforts have explored the use of deep learning to fuse disparate data into predictive models for a wide range of biomedical applications, these models often fail even when the correct answer is already known, and fail to explain individual predictions in terms that data scientists can appreciate. These limitations suggest that new methods to produce practical artificial intelligence are still needed. In this talk, I will discuss our work in (1) building an integrative knowledge infrastructure to prepare FAIR and "AI-ready" data and services along with (2) neurosymbolic AI methods to improve the quality of predictions and to generate plausible explanations. Attention is given to standards, platforms, and methods to wrangle knowledge into simple, but effective semantic and latent representations, and to make these available into standards-compliant and discoverable interfaces that can be used in model building, validation, and explanation. Our work, and those of others in the field, creates a baseline for building trustworthy and easy to deploy AI models in biomedicine. Bio Dr. Michel Dumontier is the Distinguished Professor of Data Science at Maastricht University, founder and executive director of the Institute of Data Science, and co-founder of the FAIR (Findable, Accessible, Interoperable and Reusable) data principles. His research explores socio-technological approaches for responsible discovery science, which includes collaborative multi-modal knowledge graphs, privacy-preserving distributed data mining, and AI methods for drug discovery and personalized medicine. His work is supported through the Dutch National Research Agenda, the Netherlands Organisation for Scientific Research, Horizon Europe, the European Open Science Cloud, the US National Institutes of Health, and a Marie-Curie Innovative Training Network. He is the editor-in-chief for the journal Data Science and is internationally recognized for his contributions in bioinformatics, biomedical informatics, and semantic technologies including ontologies and linked data.

FAIR & AI Ready KGs for Explainable Predictions

Michel Dumontier

The ambient solar wind that flls the heliosphere originates from multiple sources in the solar corona and is highly structured. It is often described as high-speed, relatively homogeneous, plasma streams from coronal holes and slow-speed, highly variable, streams whose source regions are under debate. A key goal of ESA/NASA’s Solar Orbiter mission is to identify solar wind sources and understand what drives the complexity seen in the heliosphere. By combining magnetic feld modelling and spectroscopic techniques with high-resolution observations and measurements, we show that the solar wind variability detected in situ by Solar Orbiter in March 2022 is driven by spatio-temporal changes in the magnetic connectivity to multiple sources in the solar atmosphere. The magnetic feld footpoints connected to the spacecraft moved from the boundaries of a coronal hole to one active region (12961) and then across to another region (12957). This is refected in the in situ measurements, which show the transition from fast to highly Alfvénic then to slow solar wind that is disrupted by the arrival of a coronal mass ejection. Our results describe solar wind variability at 0.5 au but are applicable to near-Earth observatories.

Multi-source connectivity as the driver of solar wind variability in the heli...

Sérgio Sacani

PESTS OF GREEN MANURE CROPS AND FORAGE CROPS SESBANIA BORERS 1. Sesbania stem borer, Azygophleps scalaris, Cossidae, Lepidoptera Symptom of damage: Drying of sesbania plants. Nature of damage: Stoutly built larva bores into the stem and feeds, the faecal matter getting accumulated at the entrance hole. Egg: Laid in masses attached to the leaflets. Larva: Robust larva of 7 cm length, light brown with a reddish brown head. Pupa: Pupa has spines anteriorly with the help of which it moves up and down inside the tunnel in the stem. Adult: Sluggish yellowish brown moth. 2. Stem weevil, Alcidodes bubo, Curculionidae, Coleoptera Symptom of damage: Drying of the terminal branches or whole plant, lodging of the plants during monsoon seasons; affected stem with numerous bore holes and swelling symptoms. Presence of apodous grub inside the stem. Nature of damage: Grubs riddle into stem and cause thickenings on stem. The growth and vigour of the plants are impaired to a great extent. Egg: Laid on the stem. Grub : Apodous whitish grub. Adult: Reddish brown weevil with white transverse markings on the elytra. LEAF FEEDERS 3. Green semilooper, Pericyma glaucinans, Noctuidae, Lepidoptera Symptom of damage: Defoliation of plants preceding with leaflets damage. Nature of damage: Caterpillar feeds on the leaflets remaining along the ribs of leaves. Larva : Pale green, semilooper with broad yellow lateral stripes. Adult: Dark brown with black lines 4. Green looper, Semiothisa pervelgata, Semiothisa emersaria, Geometridae, Lepidoptera Symptom of damage: Defoliation of plants preceding with leaflets damage. Nature of damage: Larvae feed on the leaves. Egg: Oval greenish eggs laid singly on leaves. Larva : Pale green looper with white lines and when full grown becomes pink with horizontal bands of violet patches dorsally on the abdominal segments. Pupa: Pupates in the soil. Adult: White colour with three dark lines and spots on the wings.

Pests of Green Manures_Bionomics_IPM_Dr.UPR.pdf

PirithiRaju

Knowledge Graphs (KGs) have emerged as a valuable tool for supporting humanities scholars and cultural heritage organisations. In this resource paper, we present the Musical Meetups Knowledge Graph (MMKG), a collection of evidence of historical collaborations between personalities relevant to the music history domain. We illustrate how we built the KG with a hybrid methodology that, combining knowledge engineering with natural language processing, including the use of Large Language Models (LLM), machine learning, and other techniques, identifies the constituent elements of a historical meetup. MMKG is a network of historical meetups extracted from ∼33k biographies collected from Wikipedia focused on European musical culture between 1800 and 1945. We discuss how, by providing a structured representation of social interactions, MMKG supports digital humanities applications and music historians’ research, teaching, and learning.

Musical Meetups Knowledge Graph (MMKG): a collection of evidence for historic...

Alba Morales

insect taxonomy importance systematics and classification

anitaento25

Within the uncertainties of involved astronomical and biological parameters, the Drake Equation typically predicts that there should be many exoplanets in our galaxy hosting active, communicative civilizations (ACCs). These optimistic calculations are however not supported by evidence, which is often referred to as the Fermi Paradox. Here, we elaborate on this long-standing enigma by showing the importance of planetary tectonic style for biological evolution. We summarize growing evidence that a prolonged transition from Mesoproterozoic active single lid tectonics (1.6 to 1.0 Ga) to modern plate tectonics occurred in the Neoproterozoic Era (1.0 to 0.541 Ga), which dramatically accelerated emergence and evolution of complex species. We further suggest that both continents and oceans are required for ACCs because early evolution of simple life must happen in water but late evolution of advanced life capable of creating technology must happen on land. We resolve the Fermi Paradox (1) by adding two additional terms to the Drake Equation: foc (the fraction of habitable exoplanets with significant continents and oceans) and fpt (the fraction of habitable exoplanets with significant continents and oceans that have had plate tectonics operating for at least 0.5 Ga); and (2) by demonstrating that the product of foc and fpt is very small (< 0.00003–0.002). We propose that the lack of evidence for ACCs reflects the scarcity of long-lived plate tectonics and/or continents and oceans on exoplanets with primitive life.

The importance of continents, oceans and plate tectonics for the evolution of...

Sérgio Sacani

Mammalian Pineal Body Structure and Also Functions

YOGESH DOGRA

platelets- lifespan -Clot retraction-disorders.pptx

muralinath2

Hadean zircons provide a potential record of Earth's earliest subduction 4.3 billion years ago. Itremains enigmatic how subduction could be initiated so soon after the presumably Moon‐forming giant impact(MGI). Earlier studies found an increase in Earth's core‐mantle boundary (CMB) temperature due to theaccumulation of the impactor's core, and our recent work shows Earth's lower mantle remains largely solid, withsome of the impactor's mantle potentially surviving as the large low‐shear velocity provinces (LLSVPs). Here,we show that a hot post‐impact CMB drives the initiation of strong mantle plumes that can induce subductioninitiation ∼200 Myr after the MGI. 2D and 3D thermomechanical computations show that a high CMBtemperature is the primary factor triggering early subduction, with enrichment of heat‐producing elements inLLSVPs as another potential factor. The models link the earliest subduction to the MGI with implications forunderstanding the diverse tectonic regimes of rocky planets.

A Giant Impact Origin for the First Subduction on Earth

Sérgio Sacani

GBSN - Biochemistry (Unit 5) Chemistry of Lipids

Areesha Ahmad

The return of a sample of near-surface atmosphere from Mars would facilitate answers to several first-order science questions surrounding the formation and evolution of the planet. One of the important aspects of terrestrial planet formation in general is the role that primary atmospheres played in influencing the chemistry and structure of the planets and their antecedents. Studies of the martian atmosphere can be used to investigate the role of a primary atmosphere in its history. Atmosphere samples would also inform our understanding of the near-surface chemistry of the planet, and ultimately the prospects for life. High-precision isotopic analyses of constituent gases are needed to address these questions, requiring that the analyses are made on returned samples rather than in situ.

THE IMPORTANCE OF MARTIAN ATMOSPHERE SAMPLE RETURN.

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https://www.hubspot.com/state-of-marketing · Scaling relationships and proving ROI · Social media is the place for search, sales, and service · Authentic influencer partnerships fuel brand growth · The strongest connections happen via call, click, chat, and camera. · Time saved with AI leads to more creative work · Seeking: A single source of truth · TLDR; Get on social, try AI, and align your systems. · More human marketing, powered by robots

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ChatGPT is a revolutionary addition to the world since its introduction in 2022. A big shift in the sector of information gathering and processing happened because of this chatbot. What is the story of ChatGPT? How is the bot responding to prompts and generating contents? Swipe through these slides prepared by Expeed Software, a web development company regarding the development and technical intricacies of ChatGPT!

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Mental health has been in the news quite a bit lately. Dozens of U.S. states are currently suing Meta for contributing to the youth mental health crisis by inserting addictive features into their products, while the U.S. Surgeon General is touring the nation to bring awareness to the growing epidemic of loneliness and isolation. The country has endured periods of low national morale, such as in the 1970s when high inflation and the energy crisis worsened public sentiment following the Vietnam War. The current mood, however, feels different. Gallup recently reported that national mental health is at an all-time low, with few bright spots to lift spirits. To better understand how Americans are feeling and their attitudes towards mental health in general, ThinkNow conducted a nationally representative quantitative survey of 1,500 respondents and found some interesting differences among ethnic, age and gender groups. Technology For example, 52% agree that technology and social media have a negative impact on mental health, but when broken out by race, 61% of Whites felt technology had a negative effect, and only 48% of Hispanics thought it did. While technology has helped us keep in touch with friends and family in faraway places, it appears to have degraded our ability to connect in person. Staying connected online is a double-edged sword since the same news feed that brings us pictures of the grandkids and fluffy kittens also feeds us news about the wars in Israel and Ukraine, the dysfunction in Washington, the latest mass shooting and the climate crisis. Hispanics may have a built-in defense against the isolation technology breeds, owing to their large, multigenerational households, strong social support systems, and tendency to use social media to stay connected with relatives abroad. Age and Gender When asked how individuals rate their mental health, men rate it higher than women by 11 percentage points, and Baby Boomers rank it highest at 83%, saying it’s good or excellent vs. 57% of Gen Z saying the same. Gen Z spends the most amount of time on social media, so the notion that social media negatively affects mental health appears to be correlated. Unfortunately, Gen Z is also the generation that’s least comfortable discussing mental health concerns with healthcare professionals. Only 40% of them state they’re comfortable discussing their issues with a professional compared to 60% of Millennials and 65% of Boomers. Race Affects Attitudes As seen in previous research conducted by ThinkNow, Asian Americans lag other groups when it comes to awareness of mental health issues. Twenty-four percent of Asian Americans believe that having a mental health issue is a sign of weakness compared to the 16% average for all groups. Asians are also considerably less likely to be aware of mental health services in their communities (42% vs. 55%) and most likely to seek out information on social media (51% vs. 35%).

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A report by thenetworkone and Kurio. The contributing experts and agencies are (in an alphabetical order): Sylwia Rytel, Social Media Supervisor, 180heartbeats + JUNG v MATT (PL), Sharlene Jenner, Vice President - Director of Engagement Strategy, Abelson Taylor (USA), Alex Casanovas, Digital Director, Atrevia (ES), Dora Beilin, Senior Social Strategist, Barrett Hoffher (USA), Min Seo, Campaign Director, Brand New Agency (KR), Deshé M. Gully, Associate Strategist, Day One Agency (USA), Francesca Trevisan, Strategist, Different (IT), Trevor Crossman, CX and Digital Transformation Director; Olivia Hussey, Strategic Planner; Simi Srinarula, Social Media Manager, The Hallway (AUS), James Hebbert, Managing Director, Hylink (CN / UK), Mundy Álvarez, Planning Director; Pedro Rojas, Social Media Manager; Pancho González, CCO, Inbrax (CH), Oana Oprea, Head of Digital Planning, Jam Session Agency (RO), Amy Bottrill, Social Account Director, Launch (UK), Gaby Arriaga, Founder, Leonardo1452 (MX), Shantesh S Row, Creative Director, Liwa (UAE), Rajesh Mehta, Chief Strategy Officer; Dhruv Gaur, Digital Planning Lead; Leonie Mergulhao, Account Supervisor - Social Media & PR, Medulla (IN), Aurelija Plioplytė, Head of Digital & Social, Not Perfect (LI), Daiana Khaidargaliyeva, Account Manager, Osaka Labs (UK / USA), Stefanie Söhnchen, Vice President Digital, PIABO Communications (DE), Elisabeth Winiartati, Managing Consultant, Head of Global Integrated Communications; Lydia Aprina, Account Manager, Integrated Marketing and Communications; Nita Prabowo, Account Manager, Integrated Marketing and Communications; Okhi, Web Developer, PNTR Group (ID), Kei Obusan, Insights Director; Daffi Ranandi, Insights Manager, Radarr (SG), Gautam Reghunath, Co-founder & CEO, Talented (IN), Donagh Humphreys, Head of Social and Digital Innovation, THINKHOUSE (IRE), Sarah Yim, Strategy Director, Zulu Alpha Kilo (CA).

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The search marketing landscape is evolving rapidly with new technologies, and professionals, like you, rely on innovative paid search strategies to meet changing demands. It’s important that you’re ready to implement new strategies in 2024. Check this out and learn the top trends in paid search advertising that are expected to gain traction, so you can drive higher ROI more efficiently in 2024. You’ll learn: - The latest trends in AI and automation, and what this means for an evolving paid search ecosystem. - New developments in privacy and data regulation. - Emerging ad formats that are expected to make an impact next year. Watch Sreekant Lanka from iQuanti and Irina Klein from OneMain Financial as they dive into the future of paid search and explore the trends, strategies, and technologies that will shape the search marketing landscape. If you’re looking to assess your paid search strategy and design an industry-aligned plan for 2024, then this webinar is for you.

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From their humble beginnings in 1984, TED has grown into the world’s most powerful amplifier for speakers and thought-leaders to share their ideas. They have over 2,400 filmed talks (not including the 30,000+ TEDx videos) freely available online, and have hosted over 17,500 events around the world. With over one billion views in a year, it’s no wonder that so many speakers are looking to TED for ideas on how to share their message more effectively. The article “5 Public-Speaking Tips TED Gives Its Speakers”, by Carmine Gallo for Forbes, gives speakers five practical ways to connect with their audience, and effectively share their ideas on stage. Whether you are gearing up to get on a TED stage yourself, or just want to master the skills that so many of their speakers possess, these tips and quotes from Chris Anderson, the TED Talks Curator, will encourage you to make the most impactful impression on your audience. See the full article and more summaries like this on SpeakerHub here: https://speakerhub.com/blog/5-presentation-tips-ted-gives-its-speakers See the original article on Forbes here: http://www.forbes.com/forbes/welcome/?toURL=http://www.forbes.com/sites/carminegallo/2016/05/06/5-public-speaking-tips-ted-gives-its-speakers/&refURL=&referrer=#5c07a8221d9b

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Everyone is in agreement that ChatGPT (and other generative AI tools) will shape the future of work. Yet there is little consensus on exactly how, when, and to what extent this technology will change our world. Businesses that extract maximum value from ChatGPT will use it as a collaborative tool for everything from brainstorming to technical maintenance. For individuals, now is the time to pinpoint the skills the future professional will need to thrive in the AI age. Check out this presentation to understand what ChatGPT is, how it will shape the future of work, and how you can prepare to take advantage.

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