Definition:
Epidemiology is the study of the distribution and determinants of health-related states or events in populations, and the application of this study to control health problems.
Methods:
1. Descriptive – Who, when, where (person, time, place)
2. Analytical – Why, how (causes, risk factors)
3. Experimental – Interventions (clinical trials, field trials)
Aims:
Identify the cause of disease
Determine disease extent
Study natural history
Evaluate interventions
Inform public policy
Uses:
Disease surveillance
Health planning
Risk factor identification
Outcome evaluation
Setting priorities
Disease Transmission:
1. Direct – Person to person
2. Indirect – Through vectors, fomites, or airborne
3. Vertical – From mother to child
Disease Cycle:
Agent → Reservoir → Portal of Exit → Mode of Transmission → Portal of Entry → Host
Spectrum of Disease:
Exposure
Subclinical stage
Clinical disease
Recovery, disability, or death
Key Terms:
Incidence: New cases in a time period
Prevalence: All existing cases
Endemic: Constant presence
Epidemic: Sudden increase
Pandemic: Global outbreak