The document summarizes initiatives at the American University in Cairo (AUC) to advance its strategic pillars of excellence over the next few years as it enters its second century. Key points include enhancing the quality of education through curriculum and pedagogical innovations, increasing internationalization by recruiting more international students and faculty, upgrading campus facilities and cultural programming to improve the student experience, implementing new human resources and business intelligence systems to increase institutional effectiveness, and pioneering innovative educational programs such as the first blended degree partnership with MIT in the region.