STEM CELLS ENGINEERING.pptx

1. STEM CELLS
ENGINEERING
PresentedBy :
MuhammadSaeed
( M.PhilBiochemistry)
Lecturer in Biochemistry
RIC Peshawar

2.  Stem cells can be defined as cells which are not
specialized in any specific tissue or organs
 stem cells have not differentiated into other cell
types to form tissues and organs

3.  Stem cells are specialized cells that can
produce several different kinds of cells
 Just like the stem of a plant will produce
branches, leaves, and flowers, so stem cells
can usually produce many different kinds of
cells

5.  Adult Stem Cells (ASCs)
 ASCs are undifferentiated cells found living
within specific differentiated tissues in our
bodies that can renew themselves or generate
new cells

7.  ADULT STEM CELLS are stem cells found in
the umbilical cord (after live birth), fat, bone
marrow, tissue, organs, blood, etc. of a human
being.
 These cells are removed from the body of the
patient and manipulated in the laboratory

9.  After the cells multiply, the healthy cells are
separated from the diseased cells and
reinserted back into the body of the patient
 Human clinical trials show that these new cells
go to the diseased or injured body part and
begin to generate healthy cells and cure
number of diseases

10.  Adult stem cells also have the capacity to
produce many different cell types, including
neurons
 A person’s own stem cells should be the best
source of cells for transplantation

11.  Hematopoietic Stem Cells (Blood Stem
Cells)
 Mesenchymal Stem Cells
 Neural Stem Cells
 Epithelial Stem Cells
 Skin Stem Cells

12.  Diabetes
 Heart disease
 Sickle
 Cell anemia ,Leukemia
 Parkinson’s disease
 Crohn’s disease

13.  Macular degeneration
 Rheumatoid arthritis
 Paralysis
 Cancer
 Bone loss
 Vision problems
 Hair loss
 Liver disease

14.  Adult stem cells can even be injected
intravenously in large quantities and they will
migrate to where the injury is located

15.  Respect for human life
 Respect for human life requires that we
show respect for human embryos

16.  Some people believe that embryonic stem cell
transplant violates this principle, as an embryo is
destroyed during the process of stem cell line derivation
 Human dignity
 Should respect of the human dignity during stem cells
transplant

17.  There is no guarantee of how successful these
therapies will be, for example in the use of stem
cells in healing damage caused by Parkinson's
disease.
 The difficulty in finding suitable stem cell donors.

18.  The difficulty in obtaining and storing a
patient's embryonic stem cells.
 Cultured stem cells could be contaminated
with viruses which would be transferred to a
patient

19.  Mutations have been observed in stem cells
cultured for a number of generations, and
some mutated stem cells have been
observed to behave like cancer cells.

20.  Educating the public about what stem cells
can, and can't do, is important.
 Whether the benefits of stem cell research
use outweigh the objections.

21.  Much of the research is being carried out by
commercial clinics, so reported successes
are not subject to peer review