Reducing stillbirth and early neonatal death, pop up uni, 11am, 3 september 2015NHS England
Expo is the most significant annual health and social care event in the calendar, uniting more NHS and care leaders, commissioners, clinicians, voluntary sector partners, innovators and media than any other health and care event.
Expo 15 returned to Manchester and was hosted once again by NHS England. Around 5000 people a day from health and care, the voluntary sector, local government, and industry joined together at Manchester Central Convention Centre for two packed days of speakers, workshops, exhibitions and professional development.
This year, Expo was more relevant and engaging than ever before, happening within the first 100 days of the new Government, and almost 12 months after the publication of the NHS Five Year Forward View. It was also a great opportunity to check on and learn from the progress of Greater Manchester as the area prepares to take over a £6 billion devolved health and social care budget, pledging to integrate hospital, community, primary and social care and vastly improve health and well-being.
More information is available online: www.expo.nhs.uk
A COMPARATIVE ANALYSIS OF HEMATOLOGICAL INDICES IN PREGNANT WOMEN AND NON PR...FidelityP
Red blood cell (RBC) indices are individual components of a routine blood test called the complete blood count (CBC). The CBC is used to measure the quantity and physical characteristics of different types of cells found in your blood. Blood consists of RBCs, white blood cells (WBCs), and platelets that are suspended in your plasma. Platelets are cells that enable clot formation. RBCs contain hemoglobin, which carries oxygen throughout your body to all of your tissues and organs. An RBC is pale red and gets its color from hemoglobin. It’s shaped like a doughnut, but it has a thinner area in the middle instead of a hole. Your RBCs are normally all the same color, size, and shape. However, certain conditions can cause variations that impair their ability to function properly. The RBC indices measure the size, shape, and physical characteristics of the RBCs. Your doctor can use RBC indices to help diagnose the cause of anemia. Anemia is a common blood disorder in which you have too few, misshapen, or poorly functional RBCs123
Reducing stillbirth and early neonatal death, pop up uni, 11am, 3 september 2015NHS England
Expo is the most significant annual health and social care event in the calendar, uniting more NHS and care leaders, commissioners, clinicians, voluntary sector partners, innovators and media than any other health and care event.
Expo 15 returned to Manchester and was hosted once again by NHS England. Around 5000 people a day from health and care, the voluntary sector, local government, and industry joined together at Manchester Central Convention Centre for two packed days of speakers, workshops, exhibitions and professional development.
This year, Expo was more relevant and engaging than ever before, happening within the first 100 days of the new Government, and almost 12 months after the publication of the NHS Five Year Forward View. It was also a great opportunity to check on and learn from the progress of Greater Manchester as the area prepares to take over a £6 billion devolved health and social care budget, pledging to integrate hospital, community, primary and social care and vastly improve health and well-being.
More information is available online: www.expo.nhs.uk
A COMPARATIVE ANALYSIS OF HEMATOLOGICAL INDICES IN PREGNANT WOMEN AND NON PR...FidelityP
Red blood cell (RBC) indices are individual components of a routine blood test called the complete blood count (CBC). The CBC is used to measure the quantity and physical characteristics of different types of cells found in your blood. Blood consists of RBCs, white blood cells (WBCs), and platelets that are suspended in your plasma. Platelets are cells that enable clot formation. RBCs contain hemoglobin, which carries oxygen throughout your body to all of your tissues and organs. An RBC is pale red and gets its color from hemoglobin. It’s shaped like a doughnut, but it has a thinner area in the middle instead of a hole. Your RBCs are normally all the same color, size, and shape. However, certain conditions can cause variations that impair their ability to function properly. The RBC indices measure the size, shape, and physical characteristics of the RBCs. Your doctor can use RBC indices to help diagnose the cause of anemia. Anemia is a common blood disorder in which you have too few, misshapen, or poorly functional RBCs123
— This study was conducted to find out if AFI ≤ 5 cms has any clinical significance in identifying the subsequent fetal distress & associated maternal & perinatal outcomes, in pregnancies beyond 37 weeks. Methodology: This is a prospective case control study done from July 2010 to July 2012 (24 months) at Dr Vasantrao Pawar Medical College, Hospital and Research Center. Adgaon, Nashik. It study the pregnancy outcome comparison of 58 Anenatal Cases(ANCs)as Study Group with diangosis of oligohydramnios (AFI ≤ 5 cms) by ultrasound after 37 completed weeks of gestation w e r e compared with 58 ANCs (Control Group) with no oligohydramnios (AFI > 5 cms). These two groups were matched for other variables like age, parity, gestational age and any pregnancy complication. Results: There was significant difference between two groups. Hypertension and Preeclampsia were found significantly more in ANCs with oligohydramnios. FHR deceleration was also significantly higher in women with oligohydramnios. Women require LSCS were also significantly more in women with oligohydramnios. Newborn borned by women with oligohydramnios had significantly more chances to admit in NICU than in newborn born by women without oligohydramnios. Conclusion: It can be concluded from this study that women with oligohydramnios poor pregancy outcomes. Determination of AFI can be used as an adjunct to other fetal surveillance methods. Determination of AFI can be used as valuable screening test for predicting fetal distress in labour, requiring caesarean section.
Prevalence of Anamiea and Its Predictors in Pregnant Women Attending Antenata...iosrjce
Background: Anemia impairs cognitive development, reduces physical work capacity and in severe cases
increases risk of mortality particularly during prenatal period. In India, 16% of maternal deaths are attributed
to anemia. However, high prevalence of anemia among pregnant women persists in India despite the
availability of effective, low-cost interventions for prevention and treatment. Aknowledge of them
sociodemographic factors associated with anemia will help to formulate multipronged strategies to attack this
important public health problem in pregnancy.
Objective: To assess the prevalence of anaemia and its predicting factors among pregnant women attending
antenatal clinic at Tertiary care center.
Study Design: Descriptive cross-sectional study
Methods: A hospital based cross-sectional study design was conducted from January 2014 – September 2014
among 5788 pregnant womens who had been attending antenatal clinic. Red blood cell morphology and Hgb
level determination were assessed following the standard procedures. Socio-demographic data was collected by
using a structured questionnaire. The data entered and analyzed by using the SPSS version 16.0 statistical
software. P<0.05 was considered as statistically significant.
Result: Overall prevalence of anemia among the pregnant women was found to be 86.37%. Factors such as
diet, level of education of women and their husbands and socioeconomic status were found to be significantly
associated with the prevalence of anemia in pregnancy.
Conclusion: The present study showed high prevalence of anemia and the majority of them were of the
moderate type (hemoglobin: 10-10.9 g/dl). Low socioeconomic class, illiteracy, Multiparous were significantly
associated with high prevalence of anemia during pregnancy in Indian women.
Multicenter screening for pre-eclampsia by maternal factors and biomarkers at 11–13 weeks' gestation: comparison with NICE guidelines and ACOG recommendations
N. O'Gorman, D. Wright, L. C. Poon, D. L. Rolnik, A. Syngelaki, M. de Alvarado, I. F. Carbone, V. Dutemeyer, M. Fiolna, A. Frick, N. Karagiotis, S. Mastrodima, C. de Paco Matallana, G. Papaioannou, A. Pazos, W. Plasencia, K. H. Nicolaides
Volume 49, Issue 6, Pages 756–760
Slides prepared by Dr Fiona Brownfoot (UOG Editor-for-Trainees)
Read the free-access article: http://onlinelibrary.wiley.com/doi/10.1002/uog.17455/full
UOG Journal Club: September 2013
Value of adding second-trimester uterine artery Doppler to patient characteristics in identification of nulliparous women at increased risk for pre-eclampsia: an individual patient data meta-analysis
C. E. Kleinrouweler, P. M. M. Bossuyt, B. Thilaganathan, K. C. Vollebregt, J. Arenas Ramírez, A. Ohkuchi, K. L. Deurloo, M. Macleod, A. E. Diab, H. Wolf, J. A. M. van der Post, B. W. J. Mol and E. Pajkrt
Volume 42, Issue 3, Date: September 2013, pages 257–267
Link to the free-access article:
onlinelibrary.wiley.com/doi/10.1002/uog.12435/abstract
TYA and Adult Late Effects Service at UCLHUCLPartners
Presentation by Victoria Grandage of University College London Hospitals NHS Foundation Trust at the London Cancer Children, Teenager and Young Adults Study Day, held on 25 July 2013.
— This study was conducted to find out if AFI ≤ 5 cms has any clinical significance in identifying the subsequent fetal distress & associated maternal & perinatal outcomes, in pregnancies beyond 37 weeks. Methodology: This is a prospective case control study done from July 2010 to July 2012 (24 months) at Dr Vasantrao Pawar Medical College, Hospital and Research Center. Adgaon, Nashik. It study the pregnancy outcome comparison of 58 Anenatal Cases(ANCs)as Study Group with diangosis of oligohydramnios (AFI ≤ 5 cms) by ultrasound after 37 completed weeks of gestation w e r e compared with 58 ANCs (Control Group) with no oligohydramnios (AFI > 5 cms). These two groups were matched for other variables like age, parity, gestational age and any pregnancy complication. Results: There was significant difference between two groups. Hypertension and Preeclampsia were found significantly more in ANCs with oligohydramnios. FHR deceleration was also significantly higher in women with oligohydramnios. Women require LSCS were also significantly more in women with oligohydramnios. Newborn borned by women with oligohydramnios had significantly more chances to admit in NICU than in newborn born by women without oligohydramnios. Conclusion: It can be concluded from this study that women with oligohydramnios poor pregancy outcomes. Determination of AFI can be used as an adjunct to other fetal surveillance methods. Determination of AFI can be used as valuable screening test for predicting fetal distress in labour, requiring caesarean section.
Prevalence of Anamiea and Its Predictors in Pregnant Women Attending Antenata...iosrjce
Background: Anemia impairs cognitive development, reduces physical work capacity and in severe cases
increases risk of mortality particularly during prenatal period. In India, 16% of maternal deaths are attributed
to anemia. However, high prevalence of anemia among pregnant women persists in India despite the
availability of effective, low-cost interventions for prevention and treatment. Aknowledge of them
sociodemographic factors associated with anemia will help to formulate multipronged strategies to attack this
important public health problem in pregnancy.
Objective: To assess the prevalence of anaemia and its predicting factors among pregnant women attending
antenatal clinic at Tertiary care center.
Study Design: Descriptive cross-sectional study
Methods: A hospital based cross-sectional study design was conducted from January 2014 – September 2014
among 5788 pregnant womens who had been attending antenatal clinic. Red blood cell morphology and Hgb
level determination were assessed following the standard procedures. Socio-demographic data was collected by
using a structured questionnaire. The data entered and analyzed by using the SPSS version 16.0 statistical
software. P<0.05 was considered as statistically significant.
Result: Overall prevalence of anemia among the pregnant women was found to be 86.37%. Factors such as
diet, level of education of women and their husbands and socioeconomic status were found to be significantly
associated with the prevalence of anemia in pregnancy.
Conclusion: The present study showed high prevalence of anemia and the majority of them were of the
moderate type (hemoglobin: 10-10.9 g/dl). Low socioeconomic class, illiteracy, Multiparous were significantly
associated with high prevalence of anemia during pregnancy in Indian women.
Multicenter screening for pre-eclampsia by maternal factors and biomarkers at 11–13 weeks' gestation: comparison with NICE guidelines and ACOG recommendations
N. O'Gorman, D. Wright, L. C. Poon, D. L. Rolnik, A. Syngelaki, M. de Alvarado, I. F. Carbone, V. Dutemeyer, M. Fiolna, A. Frick, N. Karagiotis, S. Mastrodima, C. de Paco Matallana, G. Papaioannou, A. Pazos, W. Plasencia, K. H. Nicolaides
Volume 49, Issue 6, Pages 756–760
Slides prepared by Dr Fiona Brownfoot (UOG Editor-for-Trainees)
Read the free-access article: http://onlinelibrary.wiley.com/doi/10.1002/uog.17455/full
UOG Journal Club: September 2013
Value of adding second-trimester uterine artery Doppler to patient characteristics in identification of nulliparous women at increased risk for pre-eclampsia: an individual patient data meta-analysis
C. E. Kleinrouweler, P. M. M. Bossuyt, B. Thilaganathan, K. C. Vollebregt, J. Arenas Ramírez, A. Ohkuchi, K. L. Deurloo, M. Macleod, A. E. Diab, H. Wolf, J. A. M. van der Post, B. W. J. Mol and E. Pajkrt
Volume 42, Issue 3, Date: September 2013, pages 257–267
Link to the free-access article:
onlinelibrary.wiley.com/doi/10.1002/uog.12435/abstract
TYA and Adult Late Effects Service at UCLHUCLPartners
Presentation by Victoria Grandage of University College London Hospitals NHS Foundation Trust at the London Cancer Children, Teenager and Young Adults Study Day, held on 25 July 2013.
A Strategic Approach: GenAI in EducationPeter Windle
Artificial Intelligence (AI) technologies such as Generative AI, Image Generators and Large Language Models have had a dramatic impact on teaching, learning and assessment over the past 18 months. The most immediate threat AI posed was to Academic Integrity with Higher Education Institutes (HEIs) focusing their efforts on combating the use of GenAI in assessment. Guidelines were developed for staff and students, policies put in place too. Innovative educators have forged paths in the use of Generative AI for teaching, learning and assessments leading to pockets of transformation springing up across HEIs, often with little or no top-down guidance, support or direction.
This Gasta posits a strategic approach to integrating AI into HEIs to prepare staff, students and the curriculum for an evolving world and workplace. We will highlight the advantages of working with these technologies beyond the realm of teaching, learning and assessment by considering prompt engineering skills, industry impact, curriculum changes, and the need for staff upskilling. In contrast, not engaging strategically with Generative AI poses risks, including falling behind peers, missed opportunities and failing to ensure our graduates remain employable. The rapid evolution of AI technologies necessitates a proactive and strategic approach if we are to remain relevant.
Unit 8 - Information and Communication Technology (Paper I).pdfThiyagu K
This slides describes the basic concepts of ICT, basics of Email, Emerging Technology and Digital Initiatives in Education. This presentations aligns with the UGC Paper I syllabus.
Synthetic Fiber Construction in lab .pptxPavel ( NSTU)
Synthetic fiber production is a fascinating and complex field that blends chemistry, engineering, and environmental science. By understanding these aspects, students can gain a comprehensive view of synthetic fiber production, its impact on society and the environment, and the potential for future innovations. Synthetic fibers play a crucial role in modern society, impacting various aspects of daily life, industry, and the environment. ynthetic fibers are integral to modern life, offering a range of benefits from cost-effectiveness and versatility to innovative applications and performance characteristics. While they pose environmental challenges, ongoing research and development aim to create more sustainable and eco-friendly alternatives. Understanding the importance of synthetic fibers helps in appreciating their role in the economy, industry, and daily life, while also emphasizing the need for sustainable practices and innovation.
Read| The latest issue of The Challenger is here! We are thrilled to announce that our school paper has qualified for the NATIONAL SCHOOLS PRESS CONFERENCE (NSPC) 2024. Thank you for your unwavering support and trust. Dive into the stories that made us stand out!
The French Revolution, which began in 1789, was a period of radical social and political upheaval in France. It marked the decline of absolute monarchies, the rise of secular and democratic republics, and the eventual rise of Napoleon Bonaparte. This revolutionary period is crucial in understanding the transition from feudalism to modernity in Europe.
For more information, visit-www.vavaclasses.com
Palestine last event orientationfvgnh .pptxRaedMohamed3
An EFL lesson about the current events in Palestine. It is intended to be for intermediate students who wish to increase their listening skills through a short lesson in power point.
Acetabularia Information For Class 9 .docxvaibhavrinwa19
Acetabularia acetabulum is a single-celled green alga that in its vegetative state is morphologically differentiated into a basal rhizoid and an axially elongated stalk, which bears whorls of branching hairs. The single diploid nucleus resides in the rhizoid.
Honest Reviews of Tim Han LMA Course Program.pptxtimhan337
Personal development courses are widely available today, with each one promising life-changing outcomes. Tim Han’s Life Mastery Achievers (LMA) Course has drawn a lot of interest. In addition to offering my frank assessment of Success Insider’s LMA Course, this piece examines the course’s effects via a variety of Tim Han LMA course reviews and Success Insider comments.
The Roman Empire A Historical Colossus.pdfkaushalkr1407
The Roman Empire, a vast and enduring power, stands as one of history's most remarkable civilizations, leaving an indelible imprint on the world. It emerged from the Roman Republic, transitioning into an imperial powerhouse under the leadership of Augustus Caesar in 27 BCE. This transformation marked the beginning of an era defined by unprecedented territorial expansion, architectural marvels, and profound cultural influence.
The empire's roots lie in the city of Rome, founded, according to legend, by Romulus in 753 BCE. Over centuries, Rome evolved from a small settlement to a formidable republic, characterized by a complex political system with elected officials and checks on power. However, internal strife, class conflicts, and military ambitions paved the way for the end of the Republic. Julius Caesar’s dictatorship and subsequent assassination in 44 BCE created a power vacuum, leading to a civil war. Octavian, later Augustus, emerged victorious, heralding the Roman Empire’s birth.
Under Augustus, the empire experienced the Pax Romana, a 200-year period of relative peace and stability. Augustus reformed the military, established efficient administrative systems, and initiated grand construction projects. The empire's borders expanded, encompassing territories from Britain to Egypt and from Spain to the Euphrates. Roman legions, renowned for their discipline and engineering prowess, secured and maintained these vast territories, building roads, fortifications, and cities that facilitated control and integration.
The Roman Empire’s society was hierarchical, with a rigid class system. At the top were the patricians, wealthy elites who held significant political power. Below them were the plebeians, free citizens with limited political influence, and the vast numbers of slaves who formed the backbone of the economy. The family unit was central, governed by the paterfamilias, the male head who held absolute authority.
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Roman architecture and engineering achievements were monumental. They perfected the arch, vault, and dome, constructing enduring structures like the Colosseum, Pantheon, and aqueducts. These engineering marvels not only showcased Roman ingenuity but also served practical purposes, from public entertainment to water supply.
Introduction to AI for Nonprofits with Tapp NetworkTechSoup
Dive into the world of AI! Experts Jon Hill and Tareq Monaur will guide you through AI's role in enhancing nonprofit websites and basic marketing strategies, making it easy to understand and apply.
Introduction to AI for Nonprofits with Tapp Network
Presentation1.pptx
1. PERINATAL OUTCOMES IN WOMEN WITH SICKLE CELL
DISEASE : A MATCHED COHORT STUDY FROM LONDON
,UK
CRITICAL ASSESSMENT :- STROBE Statement
2. Title and abstract
• Perinatal outcomes in women with sickle cell disease: a matched
cohort study from London, UK
• Indicates the study’s design with a commonly used term in the title or
the abstract : YES
• Provide in the abstract an informative and balanced summary of what
was done and what was found : YES
3. INTRODUCTION
• Pregnancy in women with SCD is known to be associated with an
increased risk of maternal, fetal and sickle complications.
• increased risk of stillbirth in pregnancies complicated by SCD
• incidence of preterm birth, pre-eclampsia and small for gestational
age (SGA) were all two- to four-times higher in pregnancies to women
with SCD
• In UK there are 100–200 births to women with SCD each year, with
high healthcare utilisation and costs
4. • Royal College of Obstetricians and Gynaecologists (RCOG)
recommends multidisciplinary care through joint obstetric sickle
clinics, prophylactic folic acid to improve anaemia, penicillin to reduce
risk of infection, and low-dose aspirin
• In this study a retrospective cohort of pregnancies in women with
SCD receiving maternity care between 2007 and 2017 at a tertiary
referral centre in London were complied
• It was aimed to assess perinatal outcomes of SCD in pregnancy in a
contemporary setting with evidence-based optimal clinical
management
7. SETTINGS
• Based on women receiving maternity care at Guy’s and St Thomas’ NHS
Foundation Trust (GSTT) between 2007 and 2017.
• Over the study period, care for pregnant women with SCD at this centre was
closely aligned to the 2011 UK RCOG guideline.
8. PARTICIPANTS
• Inclusion criteria: all singleton pregnancies to women with SCD who
received antenatal care at the centre.
• For each SCD pregnancy, we randomly selected 10 singleton
pregnancies unaffected by SCD but receiving care at the same
hospital.
• 131 pregnancies to women with SCD were compared with 1310
pregnancies unaffected by SCD.
9. EXCLUSION CRITERIA
• Pregnancies with known sickle cell trait (HbAS) were
excluded.
• Approximately 17% of pregnancies potentially eligible to
be selected as comparison pregnancies had missing data
on one or more covariate and/or outcomes, these were
excluded from the selection process.
• Additionally, any pregnancy was excluded from both the
SCD pregnancy cohort and comparison group that ended
before 24 gestational Weeks.
• Pregnancies which ended in termination at any gestational
age.
10. MATCHING
• Matched on broad maternal ethnic category (Black, Asian, White,
Mixed, Other) and delivery year.
11. VARIABLES
• Outcomes
• Maternal death
• Stillbirth (fetal death ≥24 weeks and before birth),
• Pre-eclampsia/eclampsia (raised blood pressure >140/ 90 mmHg with
significant proteinuria)
• Preterm birth (<34 or <37 weeks completed gestation).
• Infant outcomes were SGA (<10th centile for gestation and sex-specific
birthweight) and infant admission to the Neonatal Unit (NNU).
• Additionally, info on induction of labour, caesarean delivery (emergency or
elective), and postpartum haemorrhage (blood loss ≥1000 ml).
12. BIAS
• SCD pregnancies seen in the setting over the time period, and
selected a comparable group of pregnancies unaffected by SCD,
matched on ethnic group and year of delivery. Adjustment for some
key maternal characteristics, such as parity and maternal age was
done.
• Care was consistently delivered according to best practice guideline,
and within a universal and free at the point of access healthcare
system.
13. STUDY SIZE
• 131 pregnancies to women with SCD were compared with 1310
pregnancies unaffected by SCD.
14. DATA SOURCES/ MEASUREMENTS
• Relevant data were extracted from electronic maternity
records, supplemented by manual abstraction from clinical
records for SCD pregnancies.
• Area deprivation was measured using the Index of Multiple
Deprivation (IMD) for England quintiles, using 2010 scores
for pregnancies during the period 2007 to 2011, and IMD
2015 for pregnancies from 2012 onwards.
• For SCD pregnancies , information was collected on the SCD
genotype.
15. STATISTICAL METHODS
• Descriptive analysis reporting outcomes by SCD status.
• Conditional Poisson regression with robust variance estimators to
estimate unadjusted and adjusted risk ratios (RRs) for the association
between SCD and perinatal outcomes.
16. STATISTICAL METHODS
• Primary analysis
• combined SCD group, with additional analysis of pregnancies to women with
the two main genotypes (HbSC and HbSS) separately.
• The reference group was always pregnancies unaffected by SCD.
• Adjusted for the following a priori covariates: maternal age, parity,
BMI, and smoking status.
• Regression modelling was restricted to outcomes where there was a
minimum of two events reported in both the SCD and comparison
group.
17. STATISTICAL METHODS
• As sensitivity analysis, all analyses were repeated generalised linear
models fitted using a Poisson distribution with a log link function,
ignoring the matched design and instead additionally adjusting for
year of delivery.
• Manual abstraction of data from medical records to minimise missing
data, and then conducted a complete-case analysis.
• Analyses were performed using Stata version 16 (Stata Corp., College
Station, TX, USA).
18. STATISTICAL METHODS (CONFOUNDER
CONTROL)
• Pregnancies with known sickle cell trait (HbAS) were excluded as
potential comparison pregnancies given the uncertainty regarding
whether these pregnancies are also at increased risk of adverse
perinatal outcome.
• Pregnancies to women with other (non-sickle) hemoglobinopathies
were also excluded.
• Differing ethnicities were matched
19. STATISTICAL METHODS
• Missing data
• Approximately 17% of pregnancies potentially eligible to be selected as
comparison pregnancies had missing data on one or more covariate and/or
outcomes, these were excluded from the selection process.
• Manual abstraction of data from medical records to minimise missing
data.
20. RESULTS
13. PARTICIPANTS
• Report numbers of individuals at each stage of study?
• Being Record based study from electronic maternity records , supplemented by
maternal records from clinical records for SCD pregnancies. ( see table I )
• Give reason for non participation at each stage
• Not applicable – study mentioned about missing data from records – reasons not
mentioned.
21. Descriptive data
14.
• Give characteristics of study participants ( eg demographic, clinical, social) and
information on exposures and potential confounders.
• Indicative number of participants with missing data for each variable of interest
• Summarise follow-up time :-
• Info summarised and shared in table I of the study shared in next slide.
22.
23. Outcome data
15.Cohort study :-Report numbers of outcome events or summary
measures over time.
• Info summarised and shared in table II of the study shared in next slide.
24.
25. Result
16.
(a) Give unadjusted estimates and, if applicable, confounder-adjusted estimates
and their precision (eg, 95% confidence interval). Make clear which
confounders were adjusted for and why they were included
Pl refer table 1 & 2 , the author has shared the confounder adjusted data as per table
SII ( not available with the transcript).
(b) Report category boundaries when continuous variables were categorized
:-As the study included only qualitative outcome variable there are no
continuous variables evaluated in the study.
26.
27.
28. Other analyses
17.
Report other analyses done- e.g. analyses of subgroups and
interactions, and sensitivity analyses
• As summarised in table II, 1 & 2.
29. Key result
18
• Summarise key results with reference to study objectives
As summarised in table II, 1 & 2.
30.
31.
32. 19. Limitation
Discuss limitations of the study, taking into account sources of potential
bias or imprecision. Discuss both direction and magnitude of any
potential bias:-
• We didn’t have sufficient power to examine the association between
SCD and maternal or fetal mortality.
• Limited data available for comparison pregnancies meant that we
were unable to include several other outcomes of interest, such as
maternal antenatal and postnatal hospital admissions, and neonatal
mortality.