The document presents a tool designed to support decision-making in diagnosing mild cognitive impairment without replacing specialist judgment. The tool uses objective data from brain imaging techniques like MRI, fMRI, DTI, and PET to detect structural changes associated with mild cognitive impairment and classify subjects with over 90% accuracy. However, the classifications should be interpreted cautiously as significant structural damage may be found in asymptomatic or very early stage patients, likely due to the role of cognitive reserve in offsetting symptoms.

1. TOOLS TO SUPPORT DECISION-MAKING IN MILD COGNITIVE
IMPAIRMENT
®
Antonio García Linares1, Domingo López Rodríguez1 and Ricardo de Abajo1
1Brain Dynamics. University of Malaga. Malaga.
Objectives: In some cases, it is difficult to diagnose dementia without evidence. It is
necessary to develop tools to support decision-making without replacing the specialist
judgment, to assist in diagnosis by presenting objective data. This work presents a tool
designed for this purpose.
MRI
fMRI
DTI
PET
CT
...
Different Evolutions
Normal Aging
Alzheimer
Gray Matter Loss in Alzheimer’s Disease with Age:
60
70
80
Conclusions: We have presented a tool to aid decision making (based on
objective data obtained from a study focused on cases with CDR =
0.5), detecting structural changes compatible with mild cognitive
impairment, and to classify subjects whose accuracy exceeds 90%.
However, this classification should be taken with caution as they may find
major structural damage in patients with asymptomatic or very early and
nonspecific symptoms, probably due to the important role of cognitive
reserve.
90
Age