2
Objectives
• To describe the main functions of the
endocrine system.
• To identify glands associated with the
endocrine gland.
• To differentiate between endocrine and
exocrine glands.
• To describe the hormones associated with
each endocrine gland.
3
Main Menu
Endocrine System Structures
Hormones
5
Endocrine System
• Is a series of ductless glands which secrete
hormones into the body
• Regulates vital body and organ functions
• Works with the nervous system to maintain
homeostasis
• Includes glands and
organs with endocrine
functions
6
Glands
• Can be classified as endocrine or exocrine
−exocrine glands have ducts to secrete onto a
surface
−endocrine glands secrete directly into the
bloodstream
7
Exocrine Glands
• Have ducts to secrete directly onto the
surface
• Are not considered a part of the endocrine
system
−do not produce hormones
• Includes:
−sebaceous glands
−sudoriferous glands
−salivary glands
−Brunner’s glands
Body Bonus: Humans have between 2,000,000 to 5,000,000 sweat
glands.
8
Endocrine Glands
• Do not have ducts and secrete directly into
the bloodstream
• Includes:
−pituitary
−hypothalamus
−pineal
−thyroid
−parathyroid
−pancreas
−adrenal
−thymus
−testes
−ovaries
9
Pituitary Gland
• Is a small gland sitting in a bony hollow in
the base of the skull beneath the brain,
behind the bridge of the nose
• Contains two main regions which secrete
different hormones
−anterior pituitary
• produces hormones
−posterior pituitary
• stores hormones
Body Bonus: The pituitary gland is located at the base of the brain but
is not considered to be part of the brain.
10
Pituitary Gland
• Is called the “master gland”
−produces many hormones which control many
different processes in the body
• Senses the body’s needs and send signals
throughout the body to
regulate functions and
maintain homeostasis
Body Bonus: The pituitary gland is approximately the size of a pea.
11
Hypothalamus
• Is a small region of the brain located
directly above the pituitary gland
• Is composed of three regions:
−anterior region
−middle region
−posterior region
12
Pituitary-Hypothalamus Complex
• Is considered the “command center”
• Coordinates messages between the
nervous system and endocrine system
• Produces hormones which:
−produce direct response in target tissues
−regulate synthesis and secretion of other
hormones
13
Pineal Gland
• Is located anterior and inferior to the
thalamus
• Is receptive to changes
in lighting in its environment
• Functions are still not
completely clear
Body Bonus: The pineal gland gets its name due to its pinecone shape.
14
Thyroid Gland
• Is a butterfly-shaped gland located in the
front of the neck
• Hormone production is dependent on
iodine
• Supports metabolic rate
15
Parathyroid Glands
• Are four tiny, round glands embedded into
the posterior side of the thyroid gland
−some people have additional glands in their
chest or neck
• Supports blood calcium levels
Body Bonus: During prenatal development, the parathyroid glands
move from the head to the neck.
16
Pancreas
• Is a digestive system organ with a
secondary endocrine function
−islets of Langerhans cell clusters secrete
hormones
• Is located posterior to
the stomach
• Supports blood sugar
regulation
17
Adrenal Glands
• Are a pair of glands located on the top of
each kidney
• Support the “fight or flight” response and
kidney function
18
Thymus
• Is a lymphatic system organ with a
secondary endocrine function
• Supports immune system development
• Is most active during infancy and early
childhood
−atrophies with age
19
Testes
• Is a reproductive system organ with a
secondary endocrine function
• Supports male reproductive system
development
20
Ovaries
• Is a reproductive system organ with a
secondary endocrine function
• Supports female reproductive system
regulation
Main Menu
22
Hormones
• Are chemical messengers used to regulate
physiology, functions and behavior
−produced by endocrine glands
• Work together to maintain homeostasis
• Produced by endocrine glands and are
secreted into the bloodstream
−travel via a transport protein
−allows hormones to affect tissues throughout
the body
Body Bonus: The term “hormone” was not officially used until 1902.
23
Hormones
• Operate based on feedback loops
−cause and effect process used to show how
the body maintains homeostasis
• Activate targeted cells by binding to
hormone receptors
−binding to the receptor initiates response from
the target cell
24
Hormones
• Structure can affect distribution, receptor
binding and functions
• Can be categorized based on chemical
structure:
−amino acids
• peptides
• proteins
• amines
−lipids
• steroids
25
Anterior Pituitary Gland
• Secretes these hormones:
−growth hormone (GH)
• promotes growth of tissues by increasing
metabolic efficiency
−thyroid stimulating hormone (TSH)
• stimulates the secretion of thyroid hormones
−adrenocorticotropic hormone (ACTH)
• regulates the adrenal gland and its hormone
secretions
Body Bonus: Human Growth Hormone levels peak during puberty and
decline every year after.
26
Anterior Pituitary Gland
• Secretes these hormones:
−follicle-stimulating hormone (FSH)
• controls the development and maintenance of
the reproductive system
−luteinizing hormone (LH)
• regulates the reproductive system and the
secretion of sex hormones
−prolactin (PRL)
• stimulates breast development and milk
production in females
27
Posterior Pituitary Gland
• Secretes these hormones:
−oxytocin (Oxt)
• responsible for inducing labor through the
contraction of uterine muscles
−anti-diuretic hormone (ADH)
• controls water reabsorption by the kidneys
28
Hypothalamus
• Secretes these hormones:
−thyrotropin-releasing hormone (TRH)
• regulates the release of thyroid-stimulating
hormone from the pituitary
−somatostatin
• also called growth hormone-inhibiting hormone
(GHIH)
• regulates the release of growth hormone
−gonadotropin-releasing hormone (GnRH)
• regulates the secretion of follicle-stimulating
hormone and luteinizing hormone
29
Hypothalamus
• Secretes these hormones:
−corticotropin-releasing hormone (CRH)
• regulates the release of adrenocorticotropic
hormone
−prolactin-releasing hormone (PRH)
• stimulates the release of prolactin
−dopamine
• also called prolactin-inhibiting hormone (PIH)
• regulates the decrease of prolactin release
−growth hormone-releasing hormone (GHRH)
• stimulates the release of growth hormone in
the pituitary gland
30
Pineal Gland
• Secretes melatonin (MEL)
−aides in maintaining the body’s internal clock
−influences the body’s circadian rhythms
−effected by the presence of light
Body Bonus: The pineal gland was once known as the “third eye”.
31
Thyroid Gland
• Secretes these hormones:
−calcitonin
• helps decrease blood calcium levels
−triiodothyronine (T3) and thyroxine (T4)
• responsible for increasing the rate of
metabolism, which regulates growth and
maturation
32
Parathyroid Gland
• Secretes these hormones:
−parathyroid hormone (PTH)
• regulates blood calcium levels by signaling
osteoclasts to release calcium from bone
33
Pancreas
• Secretes these hormones:
−insulin
• absorbs and utilizes glucose to prevent blood
sugar levels from becoming too high
−glucagon
• prevents blood sugar levels
from becoming too low by
converting other energy
sources within the body to
glucose
34
Adrenal Gland
• Secretes hormones responsible for the
“fight or flight” response:
−norepinephrine and epinephrine (adrenaline)
• elevated heart rate and blood pressure
• skin and gastrointestinal tract blood vessel
constriction
• smooth muscle dilation
• bronchiole and capillary
dilation
• elevated metabolism
35
Adrenal Gland
• Secretes these hormones:
−cortisol
• intensifies metabolism by breaking down fat,
increasing glucose production and increasing
water retention
• also possesses anti-inflammatory and anti-
allergenic properties
−aldosterone
• increases water and sodium absorption, along
with potassium excretion
36
Ovaries
• Secretes these hormones:
−estrogen
• supports development of female reproductive
system
• controls development of secondary sex
characteristics
−progesterone
• regulates menstrual cycle
• prepares body for pregnancy
−inhibin
• inhibits the release of FSH from the pituitary
gland
37
Testes
• Secretes these hormones:
−testosterone
• supports development of male reproductive
system
• controls development of secondary sex
characteristics
−inhibin
• inhibits the release of FSH from the pituitary
gland

PowerPoint-HumanAnatomyEndocrineSystemDownloadableVersion icev.pptx

  • 2.
    2 Objectives • To describethe main functions of the endocrine system. • To identify glands associated with the endocrine gland. • To differentiate between endocrine and exocrine glands. • To describe the hormones associated with each endocrine gland.
  • 3.
    3 Main Menu Endocrine SystemStructures Hormones
  • 5.
    5 Endocrine System • Isa series of ductless glands which secrete hormones into the body • Regulates vital body and organ functions • Works with the nervous system to maintain homeostasis • Includes glands and organs with endocrine functions
  • 6.
    6 Glands • Can beclassified as endocrine or exocrine −exocrine glands have ducts to secrete onto a surface −endocrine glands secrete directly into the bloodstream
  • 7.
    7 Exocrine Glands • Haveducts to secrete directly onto the surface • Are not considered a part of the endocrine system −do not produce hormones • Includes: −sebaceous glands −sudoriferous glands −salivary glands −Brunner’s glands Body Bonus: Humans have between 2,000,000 to 5,000,000 sweat glands.
  • 8.
    8 Endocrine Glands • Donot have ducts and secrete directly into the bloodstream • Includes: −pituitary −hypothalamus −pineal −thyroid −parathyroid −pancreas −adrenal −thymus −testes −ovaries
  • 9.
    9 Pituitary Gland • Isa small gland sitting in a bony hollow in the base of the skull beneath the brain, behind the bridge of the nose • Contains two main regions which secrete different hormones −anterior pituitary • produces hormones −posterior pituitary • stores hormones Body Bonus: The pituitary gland is located at the base of the brain but is not considered to be part of the brain.
  • 10.
    10 Pituitary Gland • Iscalled the “master gland” −produces many hormones which control many different processes in the body • Senses the body’s needs and send signals throughout the body to regulate functions and maintain homeostasis Body Bonus: The pituitary gland is approximately the size of a pea.
  • 11.
    11 Hypothalamus • Is asmall region of the brain located directly above the pituitary gland • Is composed of three regions: −anterior region −middle region −posterior region
  • 12.
    12 Pituitary-Hypothalamus Complex • Isconsidered the “command center” • Coordinates messages between the nervous system and endocrine system • Produces hormones which: −produce direct response in target tissues −regulate synthesis and secretion of other hormones
  • 13.
    13 Pineal Gland • Islocated anterior and inferior to the thalamus • Is receptive to changes in lighting in its environment • Functions are still not completely clear Body Bonus: The pineal gland gets its name due to its pinecone shape.
  • 14.
    14 Thyroid Gland • Isa butterfly-shaped gland located in the front of the neck • Hormone production is dependent on iodine • Supports metabolic rate
  • 15.
    15 Parathyroid Glands • Arefour tiny, round glands embedded into the posterior side of the thyroid gland −some people have additional glands in their chest or neck • Supports blood calcium levels Body Bonus: During prenatal development, the parathyroid glands move from the head to the neck.
  • 16.
    16 Pancreas • Is adigestive system organ with a secondary endocrine function −islets of Langerhans cell clusters secrete hormones • Is located posterior to the stomach • Supports blood sugar regulation
  • 17.
    17 Adrenal Glands • Area pair of glands located on the top of each kidney • Support the “fight or flight” response and kidney function
  • 18.
    18 Thymus • Is alymphatic system organ with a secondary endocrine function • Supports immune system development • Is most active during infancy and early childhood −atrophies with age
  • 19.
    19 Testes • Is areproductive system organ with a secondary endocrine function • Supports male reproductive system development
  • 20.
    20 Ovaries • Is areproductive system organ with a secondary endocrine function • Supports female reproductive system regulation Main Menu
  • 22.
    22 Hormones • Are chemicalmessengers used to regulate physiology, functions and behavior −produced by endocrine glands • Work together to maintain homeostasis • Produced by endocrine glands and are secreted into the bloodstream −travel via a transport protein −allows hormones to affect tissues throughout the body Body Bonus: The term “hormone” was not officially used until 1902.
  • 23.
    23 Hormones • Operate basedon feedback loops −cause and effect process used to show how the body maintains homeostasis • Activate targeted cells by binding to hormone receptors −binding to the receptor initiates response from the target cell
  • 24.
    24 Hormones • Structure canaffect distribution, receptor binding and functions • Can be categorized based on chemical structure: −amino acids • peptides • proteins • amines −lipids • steroids
  • 25.
    25 Anterior Pituitary Gland •Secretes these hormones: −growth hormone (GH) • promotes growth of tissues by increasing metabolic efficiency −thyroid stimulating hormone (TSH) • stimulates the secretion of thyroid hormones −adrenocorticotropic hormone (ACTH) • regulates the adrenal gland and its hormone secretions Body Bonus: Human Growth Hormone levels peak during puberty and decline every year after.
  • 26.
    26 Anterior Pituitary Gland •Secretes these hormones: −follicle-stimulating hormone (FSH) • controls the development and maintenance of the reproductive system −luteinizing hormone (LH) • regulates the reproductive system and the secretion of sex hormones −prolactin (PRL) • stimulates breast development and milk production in females
  • 27.
    27 Posterior Pituitary Gland •Secretes these hormones: −oxytocin (Oxt) • responsible for inducing labor through the contraction of uterine muscles −anti-diuretic hormone (ADH) • controls water reabsorption by the kidneys
  • 28.
    28 Hypothalamus • Secretes thesehormones: −thyrotropin-releasing hormone (TRH) • regulates the release of thyroid-stimulating hormone from the pituitary −somatostatin • also called growth hormone-inhibiting hormone (GHIH) • regulates the release of growth hormone −gonadotropin-releasing hormone (GnRH) • regulates the secretion of follicle-stimulating hormone and luteinizing hormone
  • 29.
    29 Hypothalamus • Secretes thesehormones: −corticotropin-releasing hormone (CRH) • regulates the release of adrenocorticotropic hormone −prolactin-releasing hormone (PRH) • stimulates the release of prolactin −dopamine • also called prolactin-inhibiting hormone (PIH) • regulates the decrease of prolactin release −growth hormone-releasing hormone (GHRH) • stimulates the release of growth hormone in the pituitary gland
  • 30.
    30 Pineal Gland • Secretesmelatonin (MEL) −aides in maintaining the body’s internal clock −influences the body’s circadian rhythms −effected by the presence of light Body Bonus: The pineal gland was once known as the “third eye”.
  • 31.
    31 Thyroid Gland • Secretesthese hormones: −calcitonin • helps decrease blood calcium levels −triiodothyronine (T3) and thyroxine (T4) • responsible for increasing the rate of metabolism, which regulates growth and maturation
  • 32.
    32 Parathyroid Gland • Secretesthese hormones: −parathyroid hormone (PTH) • regulates blood calcium levels by signaling osteoclasts to release calcium from bone
  • 33.
    33 Pancreas • Secretes thesehormones: −insulin • absorbs and utilizes glucose to prevent blood sugar levels from becoming too high −glucagon • prevents blood sugar levels from becoming too low by converting other energy sources within the body to glucose
  • 34.
    34 Adrenal Gland • Secreteshormones responsible for the “fight or flight” response: −norepinephrine and epinephrine (adrenaline) • elevated heart rate and blood pressure • skin and gastrointestinal tract blood vessel constriction • smooth muscle dilation • bronchiole and capillary dilation • elevated metabolism
  • 35.
    35 Adrenal Gland • Secretesthese hormones: −cortisol • intensifies metabolism by breaking down fat, increasing glucose production and increasing water retention • also possesses anti-inflammatory and anti- allergenic properties −aldosterone • increases water and sodium absorption, along with potassium excretion
  • 36.
    36 Ovaries • Secretes thesehormones: −estrogen • supports development of female reproductive system • controls development of secondary sex characteristics −progesterone • regulates menstrual cycle • prepares body for pregnancy −inhibin • inhibits the release of FSH from the pituitary gland
  • 37.
    37 Testes • Secretes thesehormones: −testosterone • supports development of male reproductive system • controls development of secondary sex characteristics −inhibin • inhibits the release of FSH from the pituitary gland