PneumaCare Limited

  ERS Product of Outstanding
        Interest Session
      4 September 2012
         Vienna Austria


        (C) PneumaCare Limited
PneumaScanTM                               Thora3DITM
    • Market Segment: Diagnosis Imaging      • Market Segment: Surgical Imaging

    • Primary Target Market: Lung            • Primary Target Market: Thoracic
      Function                                 surgery, Monitoring, and Ventilation

    • USP: Non-contact, Capture current      • USP: Regional lung-function
      and presently excluded patient           analysis, Interactive output, non-
      population, portable to patient          irradiative measurement
      bedside

    • Indications: COPD,                     • Indications : LVR/VATS, pectus,
      paediatric/neonate, cystic fibrosis,     scoliosis, diaphragmatic paralysis,
      neuromuscular, emphysema,                ventilation optimisation/weaning,
      asthma, dysfunctional breathing          hyper-Inflation, asymmetry.

11/09/2012                                                                            2
Structured Light Plethysmography
               » Structured light is projected on to the
                 patients chest
               » Cameras film the movement of the grid over
                 time
               » Software utilises video to create 3D view of
                 chest movement and calculates volume of
                 air moved
               » Output is delivered in 3D regional output on
                 the user interface
11 September 2012   4
Forced Manoeuvre Data Output
Tidal Breathing Data Output
Chest / Abdominal Data Output
Left/ Right Data Output
User Defined Regions
More than a Spirometer
• Patient Populations
  – Neonatal / Paediatric
  – Neuromuscular disease
  – Thoracic surgery
  – Trauma
  – Ventilated
  – COPD, Asthma….
11


Pre-op




          Post left thoracotomy
Post-op   and pneumonectomy
(POD3)



          Improvement
Post-op     with time
(POD8)
Neonatal
• 17 healthy new born infants
  • 7 male, 10 females
  • 9 term, 8 pre-term
  • Median weight 2.9kg
  • Correct gestation 35-40 wks



   Measured undressed, quietly
   breathing in supine position
Neonatal Breathing




                                         Chest Contribution
                                                              Abdominal Contribution



Pre feeding : breathing is chaotic and


                                                              Variance
              paradoxical (blue)

Post feeing: breathing is ordered and
             concerted (red)
                                                                         Pre-   Post-feed
PFT Applications & Partners


                     Neonate




                                   Paediatric
                   COPD
              CF
                   Neuromu
                      scular
                               Asthma
11/09/2012                                      14
Thoracic Applications & Partners

                  Mesothelioma                   Diaphragmatic
                                                      Paralysis



                                     Lung Volume
                                       Reduction
     Heartlands
                                                                      Scoliosis



                      Flail Chest

                                                            Pneumothorax
                    CHOP
11/09/2012                          Strictly Confidential                         15
Ventilation Applications & Partners
                                   Asymmetry


                 Heartlands




                                                      Optimisation



             Weaning
11/09/2012                    Strictly Confidential                  16
To discuss further business or distribution opportunities of
   the PneumaCare family of products, please contact:
                       Ward Hills – Chief Executive
                       Ward.Hills@pneumacare.com


Eric Stewart – Commercial Director    Dr Richard Iles – Medical Director/CMO
  Eric.Stewart@pneumacare.com             Richard.Iles@pneumacare.com


                           PneumaCare Limited
                       St. Johns Innovation Centre
                                Cowley Rd
                           Cambridge CB4 0WS
                             +44 1223 703 151
                         www.pneumacare.com

Pneuma care ers_2012-07-04_internet

  • 1.
    PneumaCare Limited ERS Product of Outstanding Interest Session 4 September 2012 Vienna Austria (C) PneumaCare Limited
  • 2.
    PneumaScanTM Thora3DITM • Market Segment: Diagnosis Imaging • Market Segment: Surgical Imaging • Primary Target Market: Lung • Primary Target Market: Thoracic Function surgery, Monitoring, and Ventilation • USP: Non-contact, Capture current • USP: Regional lung-function and presently excluded patient analysis, Interactive output, non- population, portable to patient irradiative measurement bedside • Indications: COPD, • Indications : LVR/VATS, pectus, paediatric/neonate, cystic fibrosis, scoliosis, diaphragmatic paralysis, neuromuscular, emphysema, ventilation optimisation/weaning, asthma, dysfunctional breathing hyper-Inflation, asymmetry. 11/09/2012 2
  • 3.
    Structured Light Plethysmography » Structured light is projected on to the patients chest » Cameras film the movement of the grid over time » Software utilises video to create 3D view of chest movement and calculates volume of air moved » Output is delivered in 3D regional output on the user interface
  • 4.
  • 5.
  • 6.
  • 7.
    Chest / AbdominalData Output
  • 8.
  • 9.
  • 10.
    More than aSpirometer • Patient Populations – Neonatal / Paediatric – Neuromuscular disease – Thoracic surgery – Trauma – Ventilated – COPD, Asthma….
  • 11.
    11 Pre-op Post left thoracotomy Post-op and pneumonectomy (POD3) Improvement Post-op with time (POD8)
  • 12.
    Neonatal • 17 healthynew born infants • 7 male, 10 females • 9 term, 8 pre-term • Median weight 2.9kg • Correct gestation 35-40 wks Measured undressed, quietly breathing in supine position
  • 13.
    Neonatal Breathing Chest Contribution Abdominal Contribution Pre feeding : breathing is chaotic and Variance paradoxical (blue) Post feeing: breathing is ordered and concerted (red) Pre- Post-feed
  • 14.
    PFT Applications &Partners Neonate Paediatric COPD CF Neuromu scular Asthma 11/09/2012 14
  • 15.
    Thoracic Applications &Partners Mesothelioma Diaphragmatic Paralysis Lung Volume Reduction Heartlands Scoliosis Flail Chest Pneumothorax CHOP 11/09/2012 Strictly Confidential 15
  • 16.
    Ventilation Applications &Partners Asymmetry Heartlands Optimisation Weaning 11/09/2012 Strictly Confidential 16
  • 17.
    To discuss furtherbusiness or distribution opportunities of the PneumaCare family of products, please contact: Ward Hills – Chief Executive Ward.Hills@pneumacare.com Eric Stewart – Commercial Director Dr Richard Iles – Medical Director/CMO Eric.Stewart@pneumacare.com Richard.Iles@pneumacare.com PneumaCare Limited St. Johns Innovation Centre Cowley Rd Cambridge CB4 0WS +44 1223 703 151 www.pneumacare.com

Editor's Notes

  • #11 o   Clinical areas of approach/interest with the technology. this is where you can paint the picture of applications beyond spirometry.  You need to point to diagnostic tests that are not currently easily available. The material below is interesting with the focus on expanding the patient population. Tidal breathing in peds and adults may do that (no patient cooperation required). one caution, i don't see the PneumaScan as a screening tool for body box testing but i may be missing your intent. the body box is used to measure thoracic gas volume (VTG) and airways resistance (RAW) and most boxes have spirometry capability as well. Unless you are saying that you can use PneumaScan in some way to measure VTG (i know i don't have an NDA with you); perhaps with an occlusive shutter?? in which case you have something very interesting.
  • #12 There is no left lung post-operatively and therefore movement reflects pure chest and abdominal wall movement. This patient had a thoracotomy and shows poor ipsilateral chest wall movement on POD3 which then improves. This qualitatively correlated with his general recovery.