SlideShare a Scribd company logo
A STUDYOF THEABSORBEDDOSESIN DIFFERENTPHANTOMMATERIALS
ANDFABRICATIONOF A SUITABLEPHANTOM
Presented
By
Md. Ashikur Rahman
Scientific Officer
DRiCM, BCSIR
Dhaka
M. A. Rahman1, M. M. Rahman2, M. A. Hai2, M. A. Islam1
1Dept.of Physics, Rajshahi University;
2Cancer Centre, KYAMCH, Sirajgang
What is CANCER ?
 Surgery
 Chemotherapy
 Radiation therapy  Teletherapy
 Brachytherapy
Cancer is a large group of diseases (over 200)
characterized by uncontrolled growth and spread
of abnormal cells.
TEREATMENT OPTIONS
AIM OF RADIATION DOSIMETRY
 The prescribed dose in radiation therapy has to be converted
into machine monitor units for patient treatment.
 It is necessary to plan how we deliver the prescribed dose to a
patient.
 The dose distribution inside the patient cannot be measured
in the body of the patient himself.
 Hence, the patient needs to be replaced by a tissue-equivalent
material.
Patient is replaced by
tissue-equivalent
material to calculate
the dose inside the
body
Tissue-equivalent
material or Phantom
RADIATION DOSIMETRY
 Radiation dosimetry is the measurement and calculation
of the absorbed dose in matter and tissue
 Scientific determination of amount, rate, and distribution
of radiation emitted from a source of ionizing radiation
 Measuring the radiation-induced changes in a body or
organism and
 Measuring the levels of radiation directly with
instruments.
A phantom is a substance which is made of tissue
equivalent materials.
A phantom represents the radiation properties of the
patient and allows the introduction of a radiation detector
into this environment, a task that would be difficult in a real
patient.
A very important example is the scanning water phantom.
Alternatively, the phantom can be made of slabs of tissue
mimicking material or even shaped as a human body
(anthropomorphic).
Fig. Image of water phantom Fig. Image of PMMA phantom
Fig. Image of solid water phantom
Suitability of different Phantoms
Water phantom is widely used for dosimetry purposes and it is
recommended as the reference medium for absorbed dose
measurements for both photon and electron beam by many
international institute.
Although water phantoms are standard for absolute dosimetry
but those are inconvenient for both linac and cobult-60 machine.
Due to the problems of water phantom they are replaced by
solid phantoms which have the same properties as like as water
with slight variation.
Solid phantoms are expensive and procured with
difficulty from abroad.
It would be advantageous if an inexpensive and locally
available tissue equivalent material is available.
This is particularly relevant for developing countries like
ours.
Paraffin wax is found to have density and electron
density similar to that of water with a slight variation and
we decided to fabricate a phantom using paraffin wax.
Fig. Paraffin wax phantom
without bubbles
Fig. Paraffin wax phantom
with bubbles
CT scan image of phantom-1
(without bubbles)
CT scan image of phantom-2
(with bubbles)
FABRICATION OF PARAFFIN WAX PHANTOMS
Two paraffin wax phantoms were made one
was with bubbles and another without
bubbles.
In this study our object is to justify the suitability of
the paraffin wax phantoms and find out a scaling
factor between those readily available solid
phantoms with water phantom
Table 1: Properties of used phantom materials
Material name Chemical
Composition
Mass density
(gm/cm3)
Number of
Electrons/g
(×1023)
Water H2O 1.00 3.34
Solid water
Epoxy resin-
based mixture
1.00 3.34
PMMA (C5O2H8)n 1.16 - 1.20 3.24
Paraffin wax
CnH2n+2 ,
20 ≤ n ≤ 40
0.88 - 0.92 3.44
After making proper
dimension, two paraffin
wax phantoms were drilled
with a d.c drill machine and
the holes were similar to
the chamber dimension
The phantoms were
then placed on a CT
scanner for checking
internal integrity
Temperatures inside
phantoms were collected
by digital thermometer
and room pressures were
taken with the help of a
barometer.
Then the phantoms were placed on the couch of
the linear accelerator. The phantoms surface
center were aligned with the central axis of the
beam from the gantry at zero degree angle. The
distance between the phantoms surfaces to the
source were made 100 cm with the help of
optical mark reader.
The monitor unit of the linear accelerator was made 100,
SSD = 100 cm, Field size = 10 × 10 cm2
The readings were taken three times for
each of 6 MV and 15 MV photon beam
with the help of an electrometer in every
phantom.
Fig. Optical mark reader indicate 100 cm SSD
Fig. Linear accelerator
Two types of ionization chamber were used in the
experiment one was Farmer and another was Semi-Flex.
Absolute dosimetry protocols TG-51 and IAEA TRS 398
was followed.
Fig. Farmer type ionization chamber Fig. Semi-Flex type ionization chamber
Correction factor
The ratios between the doses in the water phantom and
those in other phantoms are scaling factors. Naturally this
scaling factor is unity for water.
A number close to 1 would be a good ratio.
Although slight variation also acceptable.
Various correction factor was calculated for the
determination of absorbed dose in different phantoms.
Absorbed dose to water at the reference depth, zref,
in a water phantom irradiated by a beam of quality
Q is
DW, Q = MQ ×ND, W × kTP × kS × kpol × kQ, Q0
MQ → Monitor reading
ND,W → Calibration factor in terms of absorbed
dose to water
kTP → Temperature pressure correction factor
kS → Ion recombination correction factor
kpol → Polarity correction factor
kQ,Q → Chamber specification factor
0
Correction for temperature and pressure
Polarity correction factor
Ion-recombination correction factor
Chamber specification factor
And,
Table 2: Scaling factor for different phantom materials for 6 MVphoton beam
Name of
phantom
Absorbed
dose in
water
phantom
Dw, Q (Gy/C)
Absorbed
dose in
phantom
Dph,Q (Gy/C)
Scaling
factor (S.F)
Dw, Q/ Dph,Q
Deviation
from
water
phantom
Paraffin wax-1
(without bubbles)
0.6892 0.6948 0.992 -0.8%
Paraffin wax-2
(with bubbles)
0.6892 0.7051 0.977 -2.3%
Solid water 0.6892 0.6758 1.020 +2.0%
PMMA 0.7062 0.6691 1.055 +5.5%
Table 3: Scaling factor for different phantom materials for 15 MVphoton beam
Name of
phantom
Absorbed
dose in
water
phantom
Dw, Q (Gy/C)
Absorbed
dose in
phantom
Dph,Q (Gy/C)
Scaling
factor (S.F)
Dw, Q/ Dph,Q
Deviation
from
water
phantom
Paraffin wax-1
(without bubbles)
0.8142 0.8042 1.012 +1.2%
Paraffin wax-2
(with bubbles)
0.8142 0.8350 0.975 -2.5%
Solid water 0.8142 0.7688 1.059 +5.9%
PMMA 0.8633 0.7897 1.093 +9.3%
Research findings
Deviation from water phantom is minimum for Paraffin
wax phantom and maximum for PMMA phantom. Although
in the case of solid water phantom this deviation should be
least but it varies about 6% , where the deviation of Paraffin
wax phantom is around 1%
The cost of solid water phantom is at least 3000
dollars, where the cost of Paraffin wax phantom is
ONLY 35 DOLLARS
Conclusion
Now it is seen that a Paraffin wax phantom is much more
suitable than other solid phantoms due to their availability,
price and process of fabrication.
 The scaling factor is a multiplication factor it will help us to
use any solid phantom and also convert the absorbed dose in
solid phantoms equivalent to water phantom.
Thank
You all

More Related Content

Similar to Physical society presentation ashik.pptx

TRS 398 code of practice for low KV xrays
TRS 398 code of practice for low KV xraysTRS 398 code of practice for low KV xrays
TRS 398 code of practice for low KV xrays
Nithin Sadanandan
 
Topic -Analysis of Patients specific Quality Assurance of IMRT/VMAT
Topic -Analysis of Patients specific Quality Assurance of IMRT/VMATTopic -Analysis of Patients specific Quality Assurance of IMRT/VMAT
Topic -Analysis of Patients specific Quality Assurance of IMRT/VMAT
Rajeev Kumar Pandit
 
T1200017 V0
T1200017 V0T1200017 V0
T1200017 V0
Patrick Murphy
 
Variation of dose distribution with depth and incident energy using EGSnrc Mo...
Variation of dose distribution with depth and incident energy using EGSnrc Mo...Variation of dose distribution with depth and incident energy using EGSnrc Mo...
Variation of dose distribution with depth and incident energy using EGSnrc Mo...
iosrjce
 
Out put calibration of co60
Out put calibration of co60Out put calibration of co60
Out put calibration of co60
KangkanDas3
 
Dose reduction technique in ct scan
Dose reduction technique in ct scanDose reduction technique in ct scan
Dose reduction technique in ct scan
Mohd Aiman Azmardi
 
Relative Dosimetry_02.04.2019_ Final.pptx
Relative Dosimetry_02.04.2019_ Final.pptxRelative Dosimetry_02.04.2019_ Final.pptx
Relative Dosimetry_02.04.2019_ Final.pptx
AshikurRahman204838
 
GAMmA cajjjjjjjjjjjujjjjjjjjjjjjjjjjjjjjjjjjmera old.pptx
GAMmA cajjjjjjjjjjjujjjjjjjjjjjjjjjjjjjjjjjjmera old.pptxGAMmA cajjjjjjjjjjjujjjjjjjjjjjjjjjjjjjjjjjjmera old.pptx
GAMmA cajjjjjjjjjjjujjjjjjjjjjjjjjjjjjjjjjjjmera old.pptx
TaushifulHoque
 
Calculation of air-kerma strength and dose rate constant for new BEBIG 60Co H...
Calculation of air-kerma strength and dose rate constant for new BEBIG 60Co H...Calculation of air-kerma strength and dose rate constant for new BEBIG 60Co H...
Calculation of air-kerma strength and dose rate constant for new BEBIG 60Co H...
Anwarul Islam
 
Session 5 mammography
Session 5 mammographySession 5 mammography
Unifying Dose Prescriptions in the Americas
Unifying Dose Prescriptions in the AmericasUnifying Dose Prescriptions in the Americas
Unifying Dose Prescriptions in the Americas
kent.riley
 
7-RADIATION PROTECTION IN DENTISTRY===7=2023.pdf
7-RADIATION PROTECTION IN DENTISTRY===7=2023.pdf7-RADIATION PROTECTION IN DENTISTRY===7=2023.pdf
7-RADIATION PROTECTION IN DENTISTRY===7=2023.pdf
NASERALHAQ
 
Nanocrystalline graphite humidity sensors for wearable breath monitoring appl...
Nanocrystalline graphite humidity sensors for wearable breath monitoring appl...Nanocrystalline graphite humidity sensors for wearable breath monitoring appl...
Nanocrystalline graphite humidity sensors for wearable breath monitoring appl...
Conference Papers
 
Quality Assurance Programme in Computed Tomography
Quality Assurance Programme in Computed TomographyQuality Assurance Programme in Computed Tomography
Quality Assurance Programme in Computed Tomography
Ramzee Small
 
Kott_Applied spectrocopy_2014_68_1108
Kott_Applied spectrocopy_2014_68_1108Kott_Applied spectrocopy_2014_68_1108
Kott_Applied spectrocopy_2014_68_1108
Laila Kott
 
Kott applied spectrocopy 2014_68_1108
Kott applied spectrocopy 2014_68_1108Kott applied spectrocopy 2014_68_1108
Kott applied spectrocopy 2014_68_1108
Laila Kott
 
Brachytherapy dosimetry
Brachytherapy dosimetryBrachytherapy dosimetry
Brachytherapy dosimetry
Sabari Kumar
 
jmrs156
jmrs156jmrs156
ASMS2012_Technical-small
ASMS2012_Technical-smallASMS2012_Technical-small
ASMS2012_Technical-small
jwylde
 
AlsadiqPropertiesAndConcentratio.pdf
AlsadiqPropertiesAndConcentratio.pdfAlsadiqPropertiesAndConcentratio.pdf
AlsadiqPropertiesAndConcentratio.pdf
Hamza Deeb
 

Similar to Physical society presentation ashik.pptx (20)

TRS 398 code of practice for low KV xrays
TRS 398 code of practice for low KV xraysTRS 398 code of practice for low KV xrays
TRS 398 code of practice for low KV xrays
 
Topic -Analysis of Patients specific Quality Assurance of IMRT/VMAT
Topic -Analysis of Patients specific Quality Assurance of IMRT/VMATTopic -Analysis of Patients specific Quality Assurance of IMRT/VMAT
Topic -Analysis of Patients specific Quality Assurance of IMRT/VMAT
 
T1200017 V0
T1200017 V0T1200017 V0
T1200017 V0
 
Variation of dose distribution with depth and incident energy using EGSnrc Mo...
Variation of dose distribution with depth and incident energy using EGSnrc Mo...Variation of dose distribution with depth and incident energy using EGSnrc Mo...
Variation of dose distribution with depth and incident energy using EGSnrc Mo...
 
Out put calibration of co60
Out put calibration of co60Out put calibration of co60
Out put calibration of co60
 
Dose reduction technique in ct scan
Dose reduction technique in ct scanDose reduction technique in ct scan
Dose reduction technique in ct scan
 
Relative Dosimetry_02.04.2019_ Final.pptx
Relative Dosimetry_02.04.2019_ Final.pptxRelative Dosimetry_02.04.2019_ Final.pptx
Relative Dosimetry_02.04.2019_ Final.pptx
 
GAMmA cajjjjjjjjjjjujjjjjjjjjjjjjjjjjjjjjjjjmera old.pptx
GAMmA cajjjjjjjjjjjujjjjjjjjjjjjjjjjjjjjjjjjmera old.pptxGAMmA cajjjjjjjjjjjujjjjjjjjjjjjjjjjjjjjjjjjmera old.pptx
GAMmA cajjjjjjjjjjjujjjjjjjjjjjjjjjjjjjjjjjjmera old.pptx
 
Calculation of air-kerma strength and dose rate constant for new BEBIG 60Co H...
Calculation of air-kerma strength and dose rate constant for new BEBIG 60Co H...Calculation of air-kerma strength and dose rate constant for new BEBIG 60Co H...
Calculation of air-kerma strength and dose rate constant for new BEBIG 60Co H...
 
Session 5 mammography
Session 5 mammographySession 5 mammography
Session 5 mammography
 
Unifying Dose Prescriptions in the Americas
Unifying Dose Prescriptions in the AmericasUnifying Dose Prescriptions in the Americas
Unifying Dose Prescriptions in the Americas
 
7-RADIATION PROTECTION IN DENTISTRY===7=2023.pdf
7-RADIATION PROTECTION IN DENTISTRY===7=2023.pdf7-RADIATION PROTECTION IN DENTISTRY===7=2023.pdf
7-RADIATION PROTECTION IN DENTISTRY===7=2023.pdf
 
Nanocrystalline graphite humidity sensors for wearable breath monitoring appl...
Nanocrystalline graphite humidity sensors for wearable breath monitoring appl...Nanocrystalline graphite humidity sensors for wearable breath monitoring appl...
Nanocrystalline graphite humidity sensors for wearable breath monitoring appl...
 
Quality Assurance Programme in Computed Tomography
Quality Assurance Programme in Computed TomographyQuality Assurance Programme in Computed Tomography
Quality Assurance Programme in Computed Tomography
 
Kott_Applied spectrocopy_2014_68_1108
Kott_Applied spectrocopy_2014_68_1108Kott_Applied spectrocopy_2014_68_1108
Kott_Applied spectrocopy_2014_68_1108
 
Kott applied spectrocopy 2014_68_1108
Kott applied spectrocopy 2014_68_1108Kott applied spectrocopy 2014_68_1108
Kott applied spectrocopy 2014_68_1108
 
Brachytherapy dosimetry
Brachytherapy dosimetryBrachytherapy dosimetry
Brachytherapy dosimetry
 
jmrs156
jmrs156jmrs156
jmrs156
 
ASMS2012_Technical-small
ASMS2012_Technical-smallASMS2012_Technical-small
ASMS2012_Technical-small
 
AlsadiqPropertiesAndConcentratio.pdf
AlsadiqPropertiesAndConcentratio.pdfAlsadiqPropertiesAndConcentratio.pdf
AlsadiqPropertiesAndConcentratio.pdf
 

Recently uploaded

Life upper-Intermediate B2 Workbook for student
Life upper-Intermediate B2 Workbook for studentLife upper-Intermediate B2 Workbook for student
Life upper-Intermediate B2 Workbook for student
NgcHiNguyn25
 
Main Java[All of the Base Concepts}.docx
Main Java[All of the Base Concepts}.docxMain Java[All of the Base Concepts}.docx
Main Java[All of the Base Concepts}.docx
adhitya5119
 
World environment day ppt For 5 June 2024
World environment day ppt For 5 June 2024World environment day ppt For 5 June 2024
World environment day ppt For 5 June 2024
ak6969907
 
LAND USE LAND COVER AND NDVI OF MIRZAPUR DISTRICT, UP
LAND USE LAND COVER AND NDVI OF MIRZAPUR DISTRICT, UPLAND USE LAND COVER AND NDVI OF MIRZAPUR DISTRICT, UP
LAND USE LAND COVER AND NDVI OF MIRZAPUR DISTRICT, UP
RAHUL
 
Hindi varnamala | hindi alphabet PPT.pdf
Hindi varnamala | hindi alphabet PPT.pdfHindi varnamala | hindi alphabet PPT.pdf
Hindi varnamala | hindi alphabet PPT.pdf
Dr. Mulla Adam Ali
 
Walmart Business+ and Spark Good for Nonprofits.pdf
Walmart Business+ and Spark Good for Nonprofits.pdfWalmart Business+ and Spark Good for Nonprofits.pdf
Walmart Business+ and Spark Good for Nonprofits.pdf
TechSoup
 
Pollock and Snow "DEIA in the Scholarly Landscape, Session One: Setting Expec...
Pollock and Snow "DEIA in the Scholarly Landscape, Session One: Setting Expec...Pollock and Snow "DEIA in the Scholarly Landscape, Session One: Setting Expec...
Pollock and Snow "DEIA in the Scholarly Landscape, Session One: Setting Expec...
National Information Standards Organization (NISO)
 
Digital Artefact 1 - Tiny Home Environmental Design
Digital Artefact 1 - Tiny Home Environmental DesignDigital Artefact 1 - Tiny Home Environmental Design
Digital Artefact 1 - Tiny Home Environmental Design
amberjdewit93
 
The History of Stoke Newington Street Names
The History of Stoke Newington Street NamesThe History of Stoke Newington Street Names
The History of Stoke Newington Street Names
History of Stoke Newington
 
PCOS corelations and management through Ayurveda.
PCOS corelations and management through Ayurveda.PCOS corelations and management through Ayurveda.
PCOS corelations and management through Ayurveda.
Dr. Shivangi Singh Parihar
 
Smart-Money for SMC traders good time and ICT
Smart-Money for SMC traders good time and ICTSmart-Money for SMC traders good time and ICT
Smart-Money for SMC traders good time and ICT
simonomuemu
 
How to Build a Module in Odoo 17 Using the Scaffold Method
How to Build a Module in Odoo 17 Using the Scaffold MethodHow to Build a Module in Odoo 17 Using the Scaffold Method
How to Build a Module in Odoo 17 Using the Scaffold Method
Celine George
 
How to Fix the Import Error in the Odoo 17
How to Fix the Import Error in the Odoo 17How to Fix the Import Error in the Odoo 17
How to Fix the Import Error in the Odoo 17
Celine George
 
বাংলাদেশ অর্থনৈতিক সমীক্ষা (Economic Review) ২০২৪ UJS App.pdf
বাংলাদেশ অর্থনৈতিক সমীক্ষা (Economic Review) ২০২৪ UJS App.pdfবাংলাদেশ অর্থনৈতিক সমীক্ষা (Economic Review) ২০২৪ UJS App.pdf
বাংলাদেশ অর্থনৈতিক সমীক্ষা (Economic Review) ২০২৪ UJS App.pdf
eBook.com.bd (প্রয়োজনীয় বাংলা বই)
 
DRUGS AND ITS classification slide share
DRUGS AND ITS classification slide shareDRUGS AND ITS classification slide share
DRUGS AND ITS classification slide share
taiba qazi
 
BBR 2024 Summer Sessions Interview Training
BBR  2024 Summer Sessions Interview TrainingBBR  2024 Summer Sessions Interview Training
BBR 2024 Summer Sessions Interview Training
Katrina Pritchard
 
The Diamonds of 2023-2024 in the IGRA collection
The Diamonds of 2023-2024 in the IGRA collectionThe Diamonds of 2023-2024 in the IGRA collection
The Diamonds of 2023-2024 in the IGRA collection
Israel Genealogy Research Association
 
Chapter 4 - Islamic Financial Institutions in Malaysia.pptx
Chapter 4 - Islamic Financial Institutions in Malaysia.pptxChapter 4 - Islamic Financial Institutions in Malaysia.pptx
Chapter 4 - Islamic Financial Institutions in Malaysia.pptx
Mohd Adib Abd Muin, Senior Lecturer at Universiti Utara Malaysia
 
MARY JANE WILSON, A “BOA MÃE” .
MARY JANE WILSON, A “BOA MÃE”           .MARY JANE WILSON, A “BOA MÃE”           .
MARY JANE WILSON, A “BOA MÃE” .
Colégio Santa Teresinha
 
Executive Directors Chat Leveraging AI for Diversity, Equity, and Inclusion
Executive Directors Chat  Leveraging AI for Diversity, Equity, and InclusionExecutive Directors Chat  Leveraging AI for Diversity, Equity, and Inclusion
Executive Directors Chat Leveraging AI for Diversity, Equity, and Inclusion
TechSoup
 

Recently uploaded (20)

Life upper-Intermediate B2 Workbook for student
Life upper-Intermediate B2 Workbook for studentLife upper-Intermediate B2 Workbook for student
Life upper-Intermediate B2 Workbook for student
 
Main Java[All of the Base Concepts}.docx
Main Java[All of the Base Concepts}.docxMain Java[All of the Base Concepts}.docx
Main Java[All of the Base Concepts}.docx
 
World environment day ppt For 5 June 2024
World environment day ppt For 5 June 2024World environment day ppt For 5 June 2024
World environment day ppt For 5 June 2024
 
LAND USE LAND COVER AND NDVI OF MIRZAPUR DISTRICT, UP
LAND USE LAND COVER AND NDVI OF MIRZAPUR DISTRICT, UPLAND USE LAND COVER AND NDVI OF MIRZAPUR DISTRICT, UP
LAND USE LAND COVER AND NDVI OF MIRZAPUR DISTRICT, UP
 
Hindi varnamala | hindi alphabet PPT.pdf
Hindi varnamala | hindi alphabet PPT.pdfHindi varnamala | hindi alphabet PPT.pdf
Hindi varnamala | hindi alphabet PPT.pdf
 
Walmart Business+ and Spark Good for Nonprofits.pdf
Walmart Business+ and Spark Good for Nonprofits.pdfWalmart Business+ and Spark Good for Nonprofits.pdf
Walmart Business+ and Spark Good for Nonprofits.pdf
 
Pollock and Snow "DEIA in the Scholarly Landscape, Session One: Setting Expec...
Pollock and Snow "DEIA in the Scholarly Landscape, Session One: Setting Expec...Pollock and Snow "DEIA in the Scholarly Landscape, Session One: Setting Expec...
Pollock and Snow "DEIA in the Scholarly Landscape, Session One: Setting Expec...
 
Digital Artefact 1 - Tiny Home Environmental Design
Digital Artefact 1 - Tiny Home Environmental DesignDigital Artefact 1 - Tiny Home Environmental Design
Digital Artefact 1 - Tiny Home Environmental Design
 
The History of Stoke Newington Street Names
The History of Stoke Newington Street NamesThe History of Stoke Newington Street Names
The History of Stoke Newington Street Names
 
PCOS corelations and management through Ayurveda.
PCOS corelations and management through Ayurveda.PCOS corelations and management through Ayurveda.
PCOS corelations and management through Ayurveda.
 
Smart-Money for SMC traders good time and ICT
Smart-Money for SMC traders good time and ICTSmart-Money for SMC traders good time and ICT
Smart-Money for SMC traders good time and ICT
 
How to Build a Module in Odoo 17 Using the Scaffold Method
How to Build a Module in Odoo 17 Using the Scaffold MethodHow to Build a Module in Odoo 17 Using the Scaffold Method
How to Build a Module in Odoo 17 Using the Scaffold Method
 
How to Fix the Import Error in the Odoo 17
How to Fix the Import Error in the Odoo 17How to Fix the Import Error in the Odoo 17
How to Fix the Import Error in the Odoo 17
 
বাংলাদেশ অর্থনৈতিক সমীক্ষা (Economic Review) ২০২৪ UJS App.pdf
বাংলাদেশ অর্থনৈতিক সমীক্ষা (Economic Review) ২০২৪ UJS App.pdfবাংলাদেশ অর্থনৈতিক সমীক্ষা (Economic Review) ২০২৪ UJS App.pdf
বাংলাদেশ অর্থনৈতিক সমীক্ষা (Economic Review) ২০২৪ UJS App.pdf
 
DRUGS AND ITS classification slide share
DRUGS AND ITS classification slide shareDRUGS AND ITS classification slide share
DRUGS AND ITS classification slide share
 
BBR 2024 Summer Sessions Interview Training
BBR  2024 Summer Sessions Interview TrainingBBR  2024 Summer Sessions Interview Training
BBR 2024 Summer Sessions Interview Training
 
The Diamonds of 2023-2024 in the IGRA collection
The Diamonds of 2023-2024 in the IGRA collectionThe Diamonds of 2023-2024 in the IGRA collection
The Diamonds of 2023-2024 in the IGRA collection
 
Chapter 4 - Islamic Financial Institutions in Malaysia.pptx
Chapter 4 - Islamic Financial Institutions in Malaysia.pptxChapter 4 - Islamic Financial Institutions in Malaysia.pptx
Chapter 4 - Islamic Financial Institutions in Malaysia.pptx
 
MARY JANE WILSON, A “BOA MÃE” .
MARY JANE WILSON, A “BOA MÃE”           .MARY JANE WILSON, A “BOA MÃE”           .
MARY JANE WILSON, A “BOA MÃE” .
 
Executive Directors Chat Leveraging AI for Diversity, Equity, and Inclusion
Executive Directors Chat  Leveraging AI for Diversity, Equity, and InclusionExecutive Directors Chat  Leveraging AI for Diversity, Equity, and Inclusion
Executive Directors Chat Leveraging AI for Diversity, Equity, and Inclusion
 

Physical society presentation ashik.pptx

  • 1. A STUDYOF THEABSORBEDDOSESIN DIFFERENTPHANTOMMATERIALS ANDFABRICATIONOF A SUITABLEPHANTOM Presented By Md. Ashikur Rahman Scientific Officer DRiCM, BCSIR Dhaka M. A. Rahman1, M. M. Rahman2, M. A. Hai2, M. A. Islam1 1Dept.of Physics, Rajshahi University; 2Cancer Centre, KYAMCH, Sirajgang
  • 2. What is CANCER ?  Surgery  Chemotherapy  Radiation therapy  Teletherapy  Brachytherapy Cancer is a large group of diseases (over 200) characterized by uncontrolled growth and spread of abnormal cells. TEREATMENT OPTIONS
  • 3. AIM OF RADIATION DOSIMETRY  The prescribed dose in radiation therapy has to be converted into machine monitor units for patient treatment.  It is necessary to plan how we deliver the prescribed dose to a patient.  The dose distribution inside the patient cannot be measured in the body of the patient himself.  Hence, the patient needs to be replaced by a tissue-equivalent material.
  • 4. Patient is replaced by tissue-equivalent material to calculate the dose inside the body Tissue-equivalent material or Phantom
  • 5. RADIATION DOSIMETRY  Radiation dosimetry is the measurement and calculation of the absorbed dose in matter and tissue  Scientific determination of amount, rate, and distribution of radiation emitted from a source of ionizing radiation  Measuring the radiation-induced changes in a body or organism and  Measuring the levels of radiation directly with instruments.
  • 6. A phantom is a substance which is made of tissue equivalent materials. A phantom represents the radiation properties of the patient and allows the introduction of a radiation detector into this environment, a task that would be difficult in a real patient. A very important example is the scanning water phantom. Alternatively, the phantom can be made of slabs of tissue mimicking material or even shaped as a human body (anthropomorphic).
  • 7. Fig. Image of water phantom Fig. Image of PMMA phantom Fig. Image of solid water phantom
  • 8. Suitability of different Phantoms Water phantom is widely used for dosimetry purposes and it is recommended as the reference medium for absorbed dose measurements for both photon and electron beam by many international institute. Although water phantoms are standard for absolute dosimetry but those are inconvenient for both linac and cobult-60 machine. Due to the problems of water phantom they are replaced by solid phantoms which have the same properties as like as water with slight variation.
  • 9. Solid phantoms are expensive and procured with difficulty from abroad. It would be advantageous if an inexpensive and locally available tissue equivalent material is available. This is particularly relevant for developing countries like ours. Paraffin wax is found to have density and electron density similar to that of water with a slight variation and we decided to fabricate a phantom using paraffin wax.
  • 10. Fig. Paraffin wax phantom without bubbles Fig. Paraffin wax phantom with bubbles CT scan image of phantom-1 (without bubbles) CT scan image of phantom-2 (with bubbles)
  • 11. FABRICATION OF PARAFFIN WAX PHANTOMS Two paraffin wax phantoms were made one was with bubbles and another without bubbles. In this study our object is to justify the suitability of the paraffin wax phantoms and find out a scaling factor between those readily available solid phantoms with water phantom
  • 12. Table 1: Properties of used phantom materials Material name Chemical Composition Mass density (gm/cm3) Number of Electrons/g (×1023) Water H2O 1.00 3.34 Solid water Epoxy resin- based mixture 1.00 3.34 PMMA (C5O2H8)n 1.16 - 1.20 3.24 Paraffin wax CnH2n+2 , 20 ≤ n ≤ 40 0.88 - 0.92 3.44
  • 13. After making proper dimension, two paraffin wax phantoms were drilled with a d.c drill machine and the holes were similar to the chamber dimension The phantoms were then placed on a CT scanner for checking internal integrity
  • 14. Temperatures inside phantoms were collected by digital thermometer and room pressures were taken with the help of a barometer. Then the phantoms were placed on the couch of the linear accelerator. The phantoms surface center were aligned with the central axis of the beam from the gantry at zero degree angle. The distance between the phantoms surfaces to the source were made 100 cm with the help of optical mark reader.
  • 15. The monitor unit of the linear accelerator was made 100, SSD = 100 cm, Field size = 10 × 10 cm2 The readings were taken three times for each of 6 MV and 15 MV photon beam with the help of an electrometer in every phantom. Fig. Optical mark reader indicate 100 cm SSD Fig. Linear accelerator
  • 16. Two types of ionization chamber were used in the experiment one was Farmer and another was Semi-Flex. Absolute dosimetry protocols TG-51 and IAEA TRS 398 was followed. Fig. Farmer type ionization chamber Fig. Semi-Flex type ionization chamber
  • 17. Correction factor The ratios between the doses in the water phantom and those in other phantoms are scaling factors. Naturally this scaling factor is unity for water. A number close to 1 would be a good ratio. Although slight variation also acceptable. Various correction factor was calculated for the determination of absorbed dose in different phantoms.
  • 18. Absorbed dose to water at the reference depth, zref, in a water phantom irradiated by a beam of quality Q is DW, Q = MQ ×ND, W × kTP × kS × kpol × kQ, Q0 MQ → Monitor reading ND,W → Calibration factor in terms of absorbed dose to water kTP → Temperature pressure correction factor kS → Ion recombination correction factor kpol → Polarity correction factor kQ,Q → Chamber specification factor 0
  • 19. Correction for temperature and pressure Polarity correction factor Ion-recombination correction factor Chamber specification factor And,
  • 20. Table 2: Scaling factor for different phantom materials for 6 MVphoton beam Name of phantom Absorbed dose in water phantom Dw, Q (Gy/C) Absorbed dose in phantom Dph,Q (Gy/C) Scaling factor (S.F) Dw, Q/ Dph,Q Deviation from water phantom Paraffin wax-1 (without bubbles) 0.6892 0.6948 0.992 -0.8% Paraffin wax-2 (with bubbles) 0.6892 0.7051 0.977 -2.3% Solid water 0.6892 0.6758 1.020 +2.0% PMMA 0.7062 0.6691 1.055 +5.5%
  • 21. Table 3: Scaling factor for different phantom materials for 15 MVphoton beam Name of phantom Absorbed dose in water phantom Dw, Q (Gy/C) Absorbed dose in phantom Dph,Q (Gy/C) Scaling factor (S.F) Dw, Q/ Dph,Q Deviation from water phantom Paraffin wax-1 (without bubbles) 0.8142 0.8042 1.012 +1.2% Paraffin wax-2 (with bubbles) 0.8142 0.8350 0.975 -2.5% Solid water 0.8142 0.7688 1.059 +5.9% PMMA 0.8633 0.7897 1.093 +9.3%
  • 22. Research findings Deviation from water phantom is minimum for Paraffin wax phantom and maximum for PMMA phantom. Although in the case of solid water phantom this deviation should be least but it varies about 6% , where the deviation of Paraffin wax phantom is around 1% The cost of solid water phantom is at least 3000 dollars, where the cost of Paraffin wax phantom is ONLY 35 DOLLARS
  • 23. Conclusion Now it is seen that a Paraffin wax phantom is much more suitable than other solid phantoms due to their availability, price and process of fabrication.  The scaling factor is a multiplication factor it will help us to use any solid phantom and also convert the absorbed dose in solid phantoms equivalent to water phantom.