SlideShare a Scribd company logo
1 of 10
PRESENTED BY
KHADGA RAJ ARAN (BISHAL)
BASIC CONSIDERATIONS IN
PHARMACOKINETICS
Define the pharmacokinetics
Describe the fundamental pathway of the drugs
Summarize the pharmacokinetic of drug.
OBJECTIVES
INTRODUCTION
 Routes of administration are primarily
determined by the properties of the drug.
 Classified in to 3 Major routes
 Enteral, parenteral and other routes
PHARMACOKINETICS
Mr. Drug YOU
FUNDAMENTAL PATHWAYS OF PHARMACOKINETICS
 Drugs @ site of administration
A,D,M,E.
 Routes of administration: determined
primarily by the properties of the drug,
they are Enteral, Parenteral and other
routes.
Enteral Routes
PARENTERAL
OTHER ROUTES OF ADMINISTRATION
ABSORPTION
DISTRIBUTION ELIMINATION
Cell
Blood
stream
CONCLUSION
 Suitable mathematical model for kinetics of drug.
 Support drug discovery,
 Fix a dosage regimen to the drug in clinical studies.
REFERENCES:
Text book of Bio-pharmaceutics by Gibaldi
Text of Biopharmaceutics by PL Madan
Pharmacokinetics

More Related Content

What's hot

pharmacokinetic of iv infusion
pharmacokinetic of iv infusionpharmacokinetic of iv infusion
pharmacokinetic of iv infusion
Dr.saqib habib
 

What's hot (20)

Pharma co kinetics compartmental modeling
Pharma co kinetics compartmental modeling Pharma co kinetics compartmental modeling
Pharma co kinetics compartmental modeling
 
Two compartment model iv bolus muju
Two compartment model iv bolus mujuTwo compartment model iv bolus muju
Two compartment model iv bolus muju
 
Compartment modeling ppt
Compartment modeling pptCompartment modeling ppt
Compartment modeling ppt
 
Basic concepts of pharmacokinetics
Basic concepts of pharmacokineticsBasic concepts of pharmacokinetics
Basic concepts of pharmacokinetics
 
Multi compartment models
Multi compartment models Multi compartment models
Multi compartment models
 
Basics of Pharmacokinetics
Basics of PharmacokineticsBasics of Pharmacokinetics
Basics of Pharmacokinetics
 
pharmacokinetic of iv infusion
pharmacokinetic of iv infusionpharmacokinetic of iv infusion
pharmacokinetic of iv infusion
 
PHARMACOKINETIC MODELS
PHARMACOKINETIC MODELSPHARMACOKINETIC MODELS
PHARMACOKINETIC MODELS
 
1.pharmacokinetics
1.pharmacokinetics1.pharmacokinetics
1.pharmacokinetics
 
applications of pharmacokinetics in drug development
applications of pharmacokinetics in drug developmentapplications of pharmacokinetics in drug development
applications of pharmacokinetics in drug development
 
Presentation on pharmacokinetic model by pallavi
Presentation on pharmacokinetic model by pallaviPresentation on pharmacokinetic model by pallavi
Presentation on pharmacokinetic model by pallavi
 
Pharmacokinetic models
Pharmacokinetic modelsPharmacokinetic models
Pharmacokinetic models
 
Pharmacokinetic models
Pharmacokinetic  modelsPharmacokinetic  models
Pharmacokinetic models
 
One compartment-open-model
One compartment-open-modelOne compartment-open-model
One compartment-open-model
 
Pharmacokinetics
PharmacokineticsPharmacokinetics
Pharmacokinetics
 
Basic concepts of pharmacokinetics
Basic concepts of pharmacokineticsBasic concepts of pharmacokinetics
Basic concepts of pharmacokinetics
 
Pharmacokinetics ppt
Pharmacokinetics pptPharmacokinetics ppt
Pharmacokinetics ppt
 
Pharmacokinetic (basic concepts)
Pharmacokinetic (basic concepts)Pharmacokinetic (basic concepts)
Pharmacokinetic (basic concepts)
 
Estimation of pharmacokinetic parameters
Estimation of pharmacokinetic parametersEstimation of pharmacokinetic parameters
Estimation of pharmacokinetic parameters
 
Causes of Non linear pharmacokinetics
Causes of Non linear pharmacokineticsCauses of Non linear pharmacokinetics
Causes of Non linear pharmacokinetics
 

Similar to Pharmacokinetics

Introduction_to_Pharmacology_subject.ppt
Introduction_to_Pharmacology_subject.pptIntroduction_to_Pharmacology_subject.ppt
Introduction_to_Pharmacology_subject.ppt
breenaawan
 
Cell com lecture_1-2_pharmacology_2010
Cell com lecture_1-2_pharmacology_2010Cell com lecture_1-2_pharmacology_2010
Cell com lecture_1-2_pharmacology_2010
MARWAMD
 
Gen Pharmacology Intro Bds
Gen Pharmacology Intro BdsGen Pharmacology Intro Bds
Gen Pharmacology Intro Bds
Rathnakar U P
 
Applications of pharmacokinetics in new drug development,dosage form design &...
Applications of pharmacokinetics in new drug development,dosage form design &...Applications of pharmacokinetics in new drug development,dosage form design &...
Applications of pharmacokinetics in new drug development,dosage form design &...
Malla Reddy College of Pharmacy
 

Similar to Pharmacokinetics (20)

Systems Pharmacology as a tool for future therapy development: a feasibility ...
Systems Pharmacology as a tool for future therapy development: a feasibility ...Systems Pharmacology as a tool for future therapy development: a feasibility ...
Systems Pharmacology as a tool for future therapy development: a feasibility ...
 
Introduction_to_Pharmacology_subject.ppt
Introduction_to_Pharmacology_subject.pptIntroduction_to_Pharmacology_subject.ppt
Introduction_to_Pharmacology_subject.ppt
 
Computational modeling in_drug_disposition[1]
Computational modeling in_drug_disposition[1]Computational modeling in_drug_disposition[1]
Computational modeling in_drug_disposition[1]
 
Pharmacology introduction.pptx
Pharmacology introduction.pptxPharmacology introduction.pptx
Pharmacology introduction.pptx
 
Cell com lecture_1-2_pharmacology_2010
Cell com lecture_1-2_pharmacology_2010Cell com lecture_1-2_pharmacology_2010
Cell com lecture_1-2_pharmacology_2010
 
Biopharmaceutics complete notes
Biopharmaceutics complete notes Biopharmaceutics complete notes
Biopharmaceutics complete notes
 
Gen Pharmacology Intro Bds
Gen Pharmacology Intro BdsGen Pharmacology Intro Bds
Gen Pharmacology Intro Bds
 
Pharmacology Definitions, Nomenclature and Pharmacodynamics I
Pharmacology Definitions, Nomenclature and Pharmacodynamics IPharmacology Definitions, Nomenclature and Pharmacodynamics I
Pharmacology Definitions, Nomenclature and Pharmacodynamics I
 
INTRODUCTION TO PHARMACOLOGY
INTRODUCTION TO PHARMACOLOGYINTRODUCTION TO PHARMACOLOGY
INTRODUCTION TO PHARMACOLOGY
 
Introduction to Pharmacology
Introduction to PharmacologyIntroduction to Pharmacology
Introduction to Pharmacology
 
Introduction to pharmacology
Introduction to pharmacologyIntroduction to pharmacology
Introduction to pharmacology
 
Population pharmacokinetics
Population pharmacokineticsPopulation pharmacokinetics
Population pharmacokinetics
 
biotechnology in pharmaceutical sciences perspective
 biotechnology in pharmaceutical sciences perspective biotechnology in pharmaceutical sciences perspective
biotechnology in pharmaceutical sciences perspective
 
Introduction to Bipharmaceutics.pptx
Introduction to Bipharmaceutics.pptxIntroduction to Bipharmaceutics.pptx
Introduction to Bipharmaceutics.pptx
 
ppt pharmacogenomic.pptx
ppt pharmacogenomic.pptxppt pharmacogenomic.pptx
ppt pharmacogenomic.pptx
 
Therapeutic drug monitoring
Therapeutic drug monitoringTherapeutic drug monitoring
Therapeutic drug monitoring
 
Anagha presentationon mupps
Anagha presentationon muppsAnagha presentationon mupps
Anagha presentationon mupps
 
Applications of pharmacokinetics in new drug development,dosage form design &...
Applications of pharmacokinetics in new drug development,dosage form design &...Applications of pharmacokinetics in new drug development,dosage form design &...
Applications of pharmacokinetics in new drug development,dosage form design &...
 
Drug Design
Drug DesignDrug Design
Drug Design
 
Introduction to biopharmaceutics by Kirti Goel
Introduction to biopharmaceutics by Kirti GoelIntroduction to biopharmaceutics by Kirti Goel
Introduction to biopharmaceutics by Kirti Goel
 

More from Khadga Raj (13)

Systematic approach in answering DI queries request
Systematic approach in answering   DI queries requestSystematic approach in answering   DI queries request
Systematic approach in answering DI queries request
 
Medication history interview
Medication history interviewMedication history interview
Medication history interview
 
Evaluation of bio_medical_literature
Evaluation of bio_medical_literatureEvaluation of bio_medical_literature
Evaluation of bio_medical_literature
 
Establishing a drug information centre
Establishing a drug information centreEstablishing a drug information centre
Establishing a drug information centre
 
Renal function test
Renal function testRenal function test
Renal function test
 
Cardiac function-test
Cardiac function-testCardiac function-test
Cardiac function-test
 
Pharmacoepidemiology 110727114004-phpapp01
Pharmacoepidemiology 110727114004-phpapp01Pharmacoepidemiology 110727114004-phpapp01
Pharmacoepidemiology 110727114004-phpapp01
 
Pharmacovigilance by khaga
Pharmacovigilance by khagaPharmacovigilance by khaga
Pharmacovigilance by khaga
 
Clinical trials by khadga
Clinical trials by  khadgaClinical trials by  khadga
Clinical trials by khadga
 
Drugdiscoveryanddevelopment by khadga raj
Drugdiscoveryanddevelopment by khadga rajDrugdiscoveryanddevelopment by khadga raj
Drugdiscoveryanddevelopment by khadga raj
 
Gene therapy
Gene therapyGene therapy
Gene therapy
 
Male and female reproductive toxicology
Male and female reproductive toxicologyMale and female reproductive toxicology
Male and female reproductive toxicology
 
Reproductive toxicology
Reproductive toxicologyReproductive toxicology
Reproductive toxicology
 

Recently uploaded

🌹Attapur⬅️ Vip Call Girls Hyderabad 📱9352852248 Book Well Trand Call Girls In...
🌹Attapur⬅️ Vip Call Girls Hyderabad 📱9352852248 Book Well Trand Call Girls In...🌹Attapur⬅️ Vip Call Girls Hyderabad 📱9352852248 Book Well Trand Call Girls In...
🌹Attapur⬅️ Vip Call Girls Hyderabad 📱9352852248 Book Well Trand Call Girls In...
Call Girls In Delhi Whatsup 9873940964 Enjoy Unlimited Pleasure
 
Russian Call Girls Lucknow Just Call 👉👉7877925207 Top Class Call Girl Service...
Russian Call Girls Lucknow Just Call 👉👉7877925207 Top Class Call Girl Service...Russian Call Girls Lucknow Just Call 👉👉7877925207 Top Class Call Girl Service...
Russian Call Girls Lucknow Just Call 👉👉7877925207 Top Class Call Girl Service...
adilkhan87451
 
Call Girl in Indore 8827247818 {LowPrice} ❤️ (ahana) Indore Call Girls * UPA...
Call Girl in Indore 8827247818 {LowPrice} ❤️ (ahana) Indore Call Girls  * UPA...Call Girl in Indore 8827247818 {LowPrice} ❤️ (ahana) Indore Call Girls  * UPA...
Call Girl in Indore 8827247818 {LowPrice} ❤️ (ahana) Indore Call Girls * UPA...
mahaiklolahd
 

Recently uploaded (20)

Top Rated Bangalore Call Girls Richmond Circle ⟟ 9332606886 ⟟ Call Me For Ge...
Top Rated Bangalore Call Girls Richmond Circle ⟟  9332606886 ⟟ Call Me For Ge...Top Rated Bangalore Call Girls Richmond Circle ⟟  9332606886 ⟟ Call Me For Ge...
Top Rated Bangalore Call Girls Richmond Circle ⟟ 9332606886 ⟟ Call Me For Ge...
 
O898O367676 Call Girls In Ahmedabad Escort Service Available 24×7 In Ahmedabad
O898O367676 Call Girls In Ahmedabad Escort Service Available 24×7 In AhmedabadO898O367676 Call Girls In Ahmedabad Escort Service Available 24×7 In Ahmedabad
O898O367676 Call Girls In Ahmedabad Escort Service Available 24×7 In Ahmedabad
 
Best Rate (Patna ) Call Girls Patna ⟟ 8617370543 ⟟ High Class Call Girl In 5 ...
Best Rate (Patna ) Call Girls Patna ⟟ 8617370543 ⟟ High Class Call Girl In 5 ...Best Rate (Patna ) Call Girls Patna ⟟ 8617370543 ⟟ High Class Call Girl In 5 ...
Best Rate (Patna ) Call Girls Patna ⟟ 8617370543 ⟟ High Class Call Girl In 5 ...
 
Top Rated Bangalore Call Girls Mg Road ⟟ 9332606886 ⟟ Call Me For Genuine S...
Top Rated Bangalore Call Girls Mg Road ⟟   9332606886 ⟟ Call Me For Genuine S...Top Rated Bangalore Call Girls Mg Road ⟟   9332606886 ⟟ Call Me For Genuine S...
Top Rated Bangalore Call Girls Mg Road ⟟ 9332606886 ⟟ Call Me For Genuine S...
 
Pondicherry Call Girls Book Now 9630942363 Top Class Pondicherry Escort Servi...
Pondicherry Call Girls Book Now 9630942363 Top Class Pondicherry Escort Servi...Pondicherry Call Girls Book Now 9630942363 Top Class Pondicherry Escort Servi...
Pondicherry Call Girls Book Now 9630942363 Top Class Pondicherry Escort Servi...
 
Top Rated Hyderabad Call Girls Chintal ⟟ 9332606886 ⟟ Call Me For Genuine Se...
Top Rated  Hyderabad Call Girls Chintal ⟟ 9332606886 ⟟ Call Me For Genuine Se...Top Rated  Hyderabad Call Girls Chintal ⟟ 9332606886 ⟟ Call Me For Genuine Se...
Top Rated Hyderabad Call Girls Chintal ⟟ 9332606886 ⟟ Call Me For Genuine Se...
 
Premium Bangalore Call Girls Jigani Dail 6378878445 Escort Service For Hot Ma...
Premium Bangalore Call Girls Jigani Dail 6378878445 Escort Service For Hot Ma...Premium Bangalore Call Girls Jigani Dail 6378878445 Escort Service For Hot Ma...
Premium Bangalore Call Girls Jigani Dail 6378878445 Escort Service For Hot Ma...
 
Manyata Tech Park ( Call Girls ) Bangalore ✔ 6297143586 ✔ Hot Model With Sexy...
Manyata Tech Park ( Call Girls ) Bangalore ✔ 6297143586 ✔ Hot Model With Sexy...Manyata Tech Park ( Call Girls ) Bangalore ✔ 6297143586 ✔ Hot Model With Sexy...
Manyata Tech Park ( Call Girls ) Bangalore ✔ 6297143586 ✔ Hot Model With Sexy...
 
Best Rate (Guwahati ) Call Girls Guwahati ⟟ 8617370543 ⟟ High Class Call Girl...
Best Rate (Guwahati ) Call Girls Guwahati ⟟ 8617370543 ⟟ High Class Call Girl...Best Rate (Guwahati ) Call Girls Guwahati ⟟ 8617370543 ⟟ High Class Call Girl...
Best Rate (Guwahati ) Call Girls Guwahati ⟟ 8617370543 ⟟ High Class Call Girl...
 
Top Rated Bangalore Call Girls Majestic ⟟ 9332606886 ⟟ Call Me For Genuine S...
Top Rated Bangalore Call Girls Majestic ⟟  9332606886 ⟟ Call Me For Genuine S...Top Rated Bangalore Call Girls Majestic ⟟  9332606886 ⟟ Call Me For Genuine S...
Top Rated Bangalore Call Girls Majestic ⟟ 9332606886 ⟟ Call Me For Genuine S...
 
Night 7k to 12k Navi Mumbai Call Girl Photo 👉 BOOK NOW 9833363713 👈 ♀️ night ...
Night 7k to 12k Navi Mumbai Call Girl Photo 👉 BOOK NOW 9833363713 👈 ♀️ night ...Night 7k to 12k Navi Mumbai Call Girl Photo 👉 BOOK NOW 9833363713 👈 ♀️ night ...
Night 7k to 12k Navi Mumbai Call Girl Photo 👉 BOOK NOW 9833363713 👈 ♀️ night ...
 
🌹Attapur⬅️ Vip Call Girls Hyderabad 📱9352852248 Book Well Trand Call Girls In...
🌹Attapur⬅️ Vip Call Girls Hyderabad 📱9352852248 Book Well Trand Call Girls In...🌹Attapur⬅️ Vip Call Girls Hyderabad 📱9352852248 Book Well Trand Call Girls In...
🌹Attapur⬅️ Vip Call Girls Hyderabad 📱9352852248 Book Well Trand Call Girls In...
 
(Low Rate RASHMI ) Rate Of Call Girls Jaipur ❣ 8445551418 ❣ Elite Models & Ce...
(Low Rate RASHMI ) Rate Of Call Girls Jaipur ❣ 8445551418 ❣ Elite Models & Ce...(Low Rate RASHMI ) Rate Of Call Girls Jaipur ❣ 8445551418 ❣ Elite Models & Ce...
(Low Rate RASHMI ) Rate Of Call Girls Jaipur ❣ 8445551418 ❣ Elite Models & Ce...
 
Call Girls Service Jaipur {9521753030} ❤️VVIP RIDDHI Call Girl in Jaipur Raja...
Call Girls Service Jaipur {9521753030} ❤️VVIP RIDDHI Call Girl in Jaipur Raja...Call Girls Service Jaipur {9521753030} ❤️VVIP RIDDHI Call Girl in Jaipur Raja...
Call Girls Service Jaipur {9521753030} ❤️VVIP RIDDHI Call Girl in Jaipur Raja...
 
Russian Call Girls Lucknow Just Call 👉👉7877925207 Top Class Call Girl Service...
Russian Call Girls Lucknow Just Call 👉👉7877925207 Top Class Call Girl Service...Russian Call Girls Lucknow Just Call 👉👉7877925207 Top Class Call Girl Service...
Russian Call Girls Lucknow Just Call 👉👉7877925207 Top Class Call Girl Service...
 
Russian Call Girls Service Jaipur {8445551418} ❤️PALLAVI VIP Jaipur Call Gir...
Russian Call Girls Service  Jaipur {8445551418} ❤️PALLAVI VIP Jaipur Call Gir...Russian Call Girls Service  Jaipur {8445551418} ❤️PALLAVI VIP Jaipur Call Gir...
Russian Call Girls Service Jaipur {8445551418} ❤️PALLAVI VIP Jaipur Call Gir...
 
Night 7k to 12k Chennai City Center Call Girls 👉👉 7427069034⭐⭐ 100% Genuine E...
Night 7k to 12k Chennai City Center Call Girls 👉👉 7427069034⭐⭐ 100% Genuine E...Night 7k to 12k Chennai City Center Call Girls 👉👉 7427069034⭐⭐ 100% Genuine E...
Night 7k to 12k Chennai City Center Call Girls 👉👉 7427069034⭐⭐ 100% Genuine E...
 
Most Beautiful Call Girl in Bangalore Contact on Whatsapp
Most Beautiful Call Girl in Bangalore Contact on WhatsappMost Beautiful Call Girl in Bangalore Contact on Whatsapp
Most Beautiful Call Girl in Bangalore Contact on Whatsapp
 
All Time Service Available Call Girls Marine Drive 📳 9820252231 For 18+ VIP C...
All Time Service Available Call Girls Marine Drive 📳 9820252231 For 18+ VIP C...All Time Service Available Call Girls Marine Drive 📳 9820252231 For 18+ VIP C...
All Time Service Available Call Girls Marine Drive 📳 9820252231 For 18+ VIP C...
 
Call Girl in Indore 8827247818 {LowPrice} ❤️ (ahana) Indore Call Girls * UPA...
Call Girl in Indore 8827247818 {LowPrice} ❤️ (ahana) Indore Call Girls  * UPA...Call Girl in Indore 8827247818 {LowPrice} ❤️ (ahana) Indore Call Girls  * UPA...
Call Girl in Indore 8827247818 {LowPrice} ❤️ (ahana) Indore Call Girls * UPA...
 

Pharmacokinetics