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Pfizer
American Multinational Pharmaceutical Company was started in Brooklyn,
New York. Which consists of pharmaceuticals and biotechnology products. It has a
high heritage of 172 years (Est. since 1849) by two teenagers called Charles Pfizer
and Charles Erhart.
Charles Pfizer was originally a chemist, and Charles Erhart was an confectioner.
Along with Katelyn kariko (key Scientist) made the company from scratch.
https://www.pfizer.com/people/history
https://www.bbc.com/news/business-27309851
$ 154,229
Key features
Key person: ALBERT BOURLA, DVM, PH.D (Chairman and Chief Executive Officer)
~78,500
43
125
Net assets No. of employees
Manufacturing sites
Market exist across
https://annualreview.pfizer.com/purpose
Market value
An overview
U. S. NYSE
https://www.wsj.com/market-data/quotes/PFE/financials/annual/balance-sheet
Share Fundamentals
▸ 52 WEEK RANGE - $238B
▸ MARKET CAP - N/A
▸ SHARES OUTSTANDING - 5.6Bn
▸ PUBLIC FLOAT - 0.67
▸ BETA - $533.86K
▸ REV. PER EMPLOYEE - 18.01
▸ EPS - $2.34
▸ YIELD - 3.71%
▸ DIVIDEND - $0.39
▸ EX-DIVIDEND DATE - Nov 4, 2021
▸ SHORT INTEREST - 52.18M 09/30/21
▸ P/E RATIO - 32.78 - 51.86
https://www.wsj.com/market-data/quotes/PFE/financials/annual/balance-sheet
Total revenue from pharmaceutical segments
https://www.proclinical.com/blogs/2021-7/who-are-the-top-10-pharma-companies-in-2021
Pfizer the Brand
Milestons
Path of Pfizer
1880’s
Citric acid
Key ingredient for soft
drink preparation
1900
COI
Cerrtification of
incorporation in New
Jersy (Company
registered) with 20,000
shares of $100 each share
1849
The sweet start
Santonin
(Deworming tablet)
1862
American civil war
Increase in demand
for pain killers and
anti antiseptics
https://www.pfizer.com/people/history
https://www.bbc.com/news/business-27309851
Path of Pfizer
1941
WW II
Collaboration with
Govt. scientist for
penicillin production
1950’s
The Golden Era
The age of antibiotics
(Terramycin)
1919
Citric acid production mark 2
Deep fermentation
process
1936
Fine chemicals
In Fermentation free
procedure (vit C, B2
& B12 and others)
https://www.pfizer.com/people/history
https://www.bbc.com/news/business-27309851
1960’s – 70’s
Series of antibiotics
Vibramycin – 1967
Doxycyline hyclate
Minipress - 1976
Prazocin Hcl
Path of Pfizer
1980’s
The Blockbuster
Feldene – 1980
Glucotrol – 1984
Unasyn - 1986
1952
Foray in animal housing
Agricultural division
1953
Nutritional supplement
specialist
Acquring J.B.
Roerigs & co
piroxicam
glipizide
Sulbactum - inj
https://www.pfizer.com/people/history
https://www.bbc.com/news/business-27309851
2014
Acquisition of
Baxter Int Inc.
Path of Pfizer
2015
Acquisition of
Hospira
1998
Viagra
The blue pill
2000
Share card programme
The Pfizer for living
https://www.pfizer.com/people/history
https://www.bbc.com/news/business-27309851
Worldwide revenue of Pfizer's Viagra from 2003 to 2019
(in million U.S. dollars)
https://www.statista.com/statistics/264827/pfizers-worldwide-viagra-revenue-since-2003
S W
O T
STRENGTHS
WEAKNESSES
OPPORTUNITIES
THREATS
SWOT Analysis
▸ Strengths
1. Pfizer has a very strong brand name and recall globally due to its leadership in the
pharmaceutical sector, The company has over 70,000 employees as a part of the
organization
2. Pfizer has an excellent research and development (R&D) creating innovative and
breakthrough products,
3. Mergers and acquisitions with big pharma brands increases the brand reputation of
the company, financial position and has good presence on NYSE and S&P
4. During the 2020 pandemic, Pfizer has invested more than $2 billion for research
of vaccinations
Weaknesses
1. Tough competition from other major Parma brands means limited scope
for market share growth
2. Negative brand image due to legal issues and lawsuits in the past
Opportunity
1. Strategic agreements with other pharmaceutical companies
and organizations to boost its research
2. Increasing awareness about healthcare needs and increasing demand for
quality healthcare solutions
3. Global penetration through mergers and acquisitions
Threats
1. Risk of unsuccessful new products can lead to loss of revenue
2. Regulatory environment becoming more stringent can lead to challenges in
global operations
3. Economic slowdown in European markets can lead to loss in business for
Pfizer
STP Analysis
▸ Segment
Heart disease, Obesity, psychiatric disorders, cognitive enhancers, oncology
& animal health segment , dysfunction
▸ Target Group
Large business owners & operators
▸ Positioning
Pfizer is committed to applying science and global resources to improve
health and well-being at every stage of life
Subsidiaries
▸ Hospira
▸ Array biopharma
▸ Parke- Davis
▸ Pharmacia & Upjohn
▸ Medivation
▸ Covx Research LLC
▸ King Pharmaceuticals
▸ Merdian Medical Technologies
▸ Amplyx Pharmaceuticals
▸ Wyeth Industria Farmaceutica Ltda
Product recall
Brand name Drug Reason for Recall
Chantix Varenicline (smoking cessation
treatment)
N-nitroso varenicline content
above acceptable daily intake
level can cause cancer
Children's Advil Ibuprofen Oral Suspension
(temporarily reduces fever,
relieves minor aches and pains
due to the common cold, flu,
sore throat, headaches and
toothaches)
Dosage cup provided is
marked in teaspoons and the
instructions on the label are
described in milliliters (ml)
https://www.fda.gov/drugs/drug-safety-and-availability/drug-recalls
Product recall
Brand name Drug Reason for Recall
Relpax Eletriptan hydrobromide 40
mg (Acute treatment of
migraine)
microbiological
contamination, Cause:
Bacterial dissemination from
the gut to the blood stream
Hospira Hydromorphone Hcl, inj
(Analgesic)
Due to the potential for
empty or cracked glass vials
Cause: Decrease the sterility,
infection like bacteremia or
sepsis.
https://www.fda.gov/drugs/drug-safety-and-availability/drug-recalls
CONTROVERSIES
“TOO BIG TO FAIL”
Illegal marketing of
Gabapentin
▸ In 1993, FDA approves Gabapentin
for seizure treatment ( Prompting
for research articles) Within five
years It has been widely used for off
label use.
▸ Warner Lambert admitted that, it
promoted the drug for pain,
psychiatric conditions, migraine,
and others for unapproved uses.
Company found guilty and agreed to
pay a sum of $430 million claimed
under False claim Act
Prescribing gabapentin off label: Perspectives from psychiatry, pain and neurology specialists
Christine Fukada, MSc, Jillian Clare Kohler, PhD, [...], and Murray Krahn, MD, MSc, FRCPC
PMCID: PMC3567599 / PMID: 23509590
Illegal marketing of
Baxtra
▸ In September 2009. Again, the False
Claims Act, passed on Pfizer’s
Valdecoxib for promoting
unapproved dosage levels, which
were not approved by FDA. (For the
safety concern)
Valdecoxib : the rise and fall of a COX-2 inhibitor- Inoshi Atukorala, David J Hunter PMID:
23517091 DOI: 10.1517/14656566.2013.783568
Wyeth, Rapamune -
Sirolimus
▸ Coating material used over the
implants to avoid the graft
rejection. This has been
commercially promoted by the
Pfizer group i.e. providing grants
donations to the hospitals and
doctors. It has been subjected to
verdict and received a penalty of
$491m USD
Pfizer settles U.S. marketing case related to Rapamune - Reuters Staff
https://www.reuters.com/article/us-pfizer-rapamune-idUSBRE96T14I20130730
JULY 30, 2013 11:33 PM
Too big to fail
▸ The Blue Cross Blue Shield filed a
lawsuit against Pfizer for providing
kickbacks and trips packages to
Caribbean or a sum of $2,000 as a
donation for listening to the
lectures about Baxter ( It is a
training part for the transition of
doctors to spokesperson for Pfizer )
it has been found guilty by and paid
a sum of $325 million USD as a
penalty
https://drugstorenews.com/pharmacy/report-blue-cross-blue-shield-texas-sues-pfizer
(06/11/2010) Blue Cross Blue Shield of Texas sues Pfizer- Alaric DeArment
Shiley defective heart
valves
▸ Bjork shiley owning to be as a
subsidiary of Pfizer. Some of the
heart valves produced by Bjork
shiley found to be fractured and
defective due to this around 300 to
500 people were passed away on
receiving a defective valve and it
was found by the US Department of
Justice, and the company agreed to
pay a sum of $10.75 million as a
compensation
https://www.ahajournals.org/doi/full/10.1161/CIRCULATIONAHA.104.511659
Risk of strut fracture of Björk-Shiley valves
Y van der Graaf 1, F de Waard, L A van Herwerden, J Defauw PMID: 1346279 DOI: 10.1016/0140-6736(92)91328-6
Royalty for Celebrex
▸ In 1990s, An enzyme discovered by
Dr. Daniel L. Simmons in
Birmingham University which led to
the production of Celebrax (
celecoxib - Cox 2 inhibitor & NSAID,
▸ Dr. Simmons was originally, who
was originally seeking 15% of the
profit share (~ $9.7m)
▸ later (6yrs of verdict) agreed to pay a
sum of 450 million dollars.
Pfizer Settles Celebrex Lawsuit
Intellectual Property: Drug firm logs a $450 million charge - Rick Mullin
May 4, 2012 | A version of this story appeared in Volume 90, Issue 19
The Trovafloxacin
lawsuit
▸ In 1996, Outbreak of the measles and cholera and
bacterial meningitis occurred in Nigeria
▸ On this scenario, contract research organization and
Pfizer representatives departed to Nigeria. To conduct
clinical trials, Out of 200 children who were
administered with drug for clinical trials 50 were found
passed away and others were found to develop
mentally and physically deformities and
▸ Pfizer tried to bribe the Nigerian Attorney General
Aondoakka to drop legal actions and on further
investigation the company found to be guilty and agree
to pay a sum of $30 million for the family of children's
in the study. $30 million to support the healthcare
initiatives in Kano and $10 million to cover the legal
actions.
Secret report surfaces showing that Pfizer was at fault in Nigerian drug tests- Jeanne Lenzer
PMCID: PMC1471980
PMID: 16735322
PROMOTIONS
“Breakthroughs that change patients' lives,”
Prevent motion sickness - Mareol
We make breathing the easiest thing on earth.
The widest range of products against swine
respiratory disease.
Sheep's health has nothing to fear.
Fake medicine online. Side effects may include: Get Real. Get a Prescription.
(in million U.S. dollars)
FUTURE
PROCEEDINDS
“Unlocking the pill”
The Race to RSV vaccine
Pfizer, jumping headfirst into the RSV vaccine race, kick-starts phase test
▸ Pfizer’s phase 3 clinical trial is set up to test the efficacy, immunogenicity, and safety of a
single dose of its RSV vaccine, known as RSVpreF and will include around 30,000 older
adults.
▸ In early data dropped rather quietly during second-quarter earnings just over a month
back, and to little fanfare, Pfizer said a challenge study, where vaccines were given to 62
adults under 50 who were then intentionally infected with RSV to see if the shot worked,
showed “100% observed efficacy against mild to moderate symptomatic infection
resulting from RSV.”
37 https://www.fiercebiotech.com/biotech/pfizer- Ben Adams (Senior Editor)
COLLABRATIONS
▸ PostEra enters a multi-year strategic partnership with Pfizer Inc. to advance
machine learning for Drug Discovery
▸ Pfizer and LianBio Announce Strategic Collaboration to Expand Development of
Novel Therapeutics in Greater China
▸ Pfizer’s investment in Homology is a testament to their enthusiasm for our PKU
gene therapy and gene editing programs to treat
▸ people living with this disease,” stated Arthur Tzianabos, Ph.D., President and Chief
Executive Officer of Homology Medicines
38 https://www.pfizer.com/partners
COLLABRATIONS
▸ Vivet Therapeutics and Pfizer Inc. Enter into Manufacturing Agreement for Vivet’s
▸ Investigational Gene Therapy for Wilson Disease
▸ SpringWorks Therapeutics Announces Clinical Collaboration with Pfizer Inc. to
▸ Evaluate Nirogacestat in Combination with PF‐06863135 in Patients with Relapsed
▸ or Refractory Multiple Myeloma
39 https://www.pfizer.com/partners
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Pfizer_Market_overview .pptx

  • 1.
  • 2.
  • 3. a Pfizer American Multinational Pharmaceutical Company was started in Brooklyn, New York. Which consists of pharmaceuticals and biotechnology products. It has a high heritage of 172 years (Est. since 1849) by two teenagers called Charles Pfizer and Charles Erhart. Charles Pfizer was originally a chemist, and Charles Erhart was an confectioner. Along with Katelyn kariko (key Scientist) made the company from scratch. https://www.pfizer.com/people/history https://www.bbc.com/news/business-27309851
  • 4. $ 154,229 Key features Key person: ALBERT BOURLA, DVM, PH.D (Chairman and Chief Executive Officer) ~78,500 43 125 Net assets No. of employees Manufacturing sites Market exist across https://annualreview.pfizer.com/purpose
  • 7. Share Fundamentals ▸ 52 WEEK RANGE - $238B ▸ MARKET CAP - N/A ▸ SHARES OUTSTANDING - 5.6Bn ▸ PUBLIC FLOAT - 0.67 ▸ BETA - $533.86K ▸ REV. PER EMPLOYEE - 18.01 ▸ EPS - $2.34 ▸ YIELD - 3.71% ▸ DIVIDEND - $0.39 ▸ EX-DIVIDEND DATE - Nov 4, 2021 ▸ SHORT INTEREST - 52.18M 09/30/21 ▸ P/E RATIO - 32.78 - 51.86 https://www.wsj.com/market-data/quotes/PFE/financials/annual/balance-sheet
  • 8. Total revenue from pharmaceutical segments https://www.proclinical.com/blogs/2021-7/who-are-the-top-10-pharma-companies-in-2021
  • 10. Path of Pfizer 1880’s Citric acid Key ingredient for soft drink preparation 1900 COI Cerrtification of incorporation in New Jersy (Company registered) with 20,000 shares of $100 each share 1849 The sweet start Santonin (Deworming tablet) 1862 American civil war Increase in demand for pain killers and anti antiseptics https://www.pfizer.com/people/history https://www.bbc.com/news/business-27309851
  • 11. Path of Pfizer 1941 WW II Collaboration with Govt. scientist for penicillin production 1950’s The Golden Era The age of antibiotics (Terramycin) 1919 Citric acid production mark 2 Deep fermentation process 1936 Fine chemicals In Fermentation free procedure (vit C, B2 & B12 and others) https://www.pfizer.com/people/history https://www.bbc.com/news/business-27309851
  • 12. 1960’s – 70’s Series of antibiotics Vibramycin – 1967 Doxycyline hyclate Minipress - 1976 Prazocin Hcl Path of Pfizer 1980’s The Blockbuster Feldene – 1980 Glucotrol – 1984 Unasyn - 1986 1952 Foray in animal housing Agricultural division 1953 Nutritional supplement specialist Acquring J.B. Roerigs & co piroxicam glipizide Sulbactum - inj https://www.pfizer.com/people/history https://www.bbc.com/news/business-27309851
  • 13. 2014 Acquisition of Baxter Int Inc. Path of Pfizer 2015 Acquisition of Hospira 1998 Viagra The blue pill 2000 Share card programme The Pfizer for living https://www.pfizer.com/people/history https://www.bbc.com/news/business-27309851
  • 14. Worldwide revenue of Pfizer's Viagra from 2003 to 2019 (in million U.S. dollars) https://www.statista.com/statistics/264827/pfizers-worldwide-viagra-revenue-since-2003
  • 16. SWOT Analysis ▸ Strengths 1. Pfizer has a very strong brand name and recall globally due to its leadership in the pharmaceutical sector, The company has over 70,000 employees as a part of the organization 2. Pfizer has an excellent research and development (R&D) creating innovative and breakthrough products, 3. Mergers and acquisitions with big pharma brands increases the brand reputation of the company, financial position and has good presence on NYSE and S&P 4. During the 2020 pandemic, Pfizer has invested more than $2 billion for research of vaccinations
  • 17. Weaknesses 1. Tough competition from other major Parma brands means limited scope for market share growth 2. Negative brand image due to legal issues and lawsuits in the past Opportunity 1. Strategic agreements with other pharmaceutical companies and organizations to boost its research 2. Increasing awareness about healthcare needs and increasing demand for quality healthcare solutions 3. Global penetration through mergers and acquisitions
  • 18. Threats 1. Risk of unsuccessful new products can lead to loss of revenue 2. Regulatory environment becoming more stringent can lead to challenges in global operations 3. Economic slowdown in European markets can lead to loss in business for Pfizer
  • 19. STP Analysis ▸ Segment Heart disease, Obesity, psychiatric disorders, cognitive enhancers, oncology & animal health segment , dysfunction ▸ Target Group Large business owners & operators ▸ Positioning Pfizer is committed to applying science and global resources to improve health and well-being at every stage of life
  • 20. Subsidiaries ▸ Hospira ▸ Array biopharma ▸ Parke- Davis ▸ Pharmacia & Upjohn ▸ Medivation ▸ Covx Research LLC ▸ King Pharmaceuticals ▸ Merdian Medical Technologies ▸ Amplyx Pharmaceuticals ▸ Wyeth Industria Farmaceutica Ltda
  • 21. Product recall Brand name Drug Reason for Recall Chantix Varenicline (smoking cessation treatment) N-nitroso varenicline content above acceptable daily intake level can cause cancer Children's Advil Ibuprofen Oral Suspension (temporarily reduces fever, relieves minor aches and pains due to the common cold, flu, sore throat, headaches and toothaches) Dosage cup provided is marked in teaspoons and the instructions on the label are described in milliliters (ml) https://www.fda.gov/drugs/drug-safety-and-availability/drug-recalls
  • 22. Product recall Brand name Drug Reason for Recall Relpax Eletriptan hydrobromide 40 mg (Acute treatment of migraine) microbiological contamination, Cause: Bacterial dissemination from the gut to the blood stream Hospira Hydromorphone Hcl, inj (Analgesic) Due to the potential for empty or cracked glass vials Cause: Decrease the sterility, infection like bacteremia or sepsis. https://www.fda.gov/drugs/drug-safety-and-availability/drug-recalls
  • 24. Illegal marketing of Gabapentin ▸ In 1993, FDA approves Gabapentin for seizure treatment ( Prompting for research articles) Within five years It has been widely used for off label use. ▸ Warner Lambert admitted that, it promoted the drug for pain, psychiatric conditions, migraine, and others for unapproved uses. Company found guilty and agreed to pay a sum of $430 million claimed under False claim Act Prescribing gabapentin off label: Perspectives from psychiatry, pain and neurology specialists Christine Fukada, MSc, Jillian Clare Kohler, PhD, [...], and Murray Krahn, MD, MSc, FRCPC PMCID: PMC3567599 / PMID: 23509590
  • 25. Illegal marketing of Baxtra ▸ In September 2009. Again, the False Claims Act, passed on Pfizer’s Valdecoxib for promoting unapproved dosage levels, which were not approved by FDA. (For the safety concern) Valdecoxib : the rise and fall of a COX-2 inhibitor- Inoshi Atukorala, David J Hunter PMID: 23517091 DOI: 10.1517/14656566.2013.783568
  • 26. Wyeth, Rapamune - Sirolimus ▸ Coating material used over the implants to avoid the graft rejection. This has been commercially promoted by the Pfizer group i.e. providing grants donations to the hospitals and doctors. It has been subjected to verdict and received a penalty of $491m USD Pfizer settles U.S. marketing case related to Rapamune - Reuters Staff https://www.reuters.com/article/us-pfizer-rapamune-idUSBRE96T14I20130730 JULY 30, 2013 11:33 PM
  • 27. Too big to fail ▸ The Blue Cross Blue Shield filed a lawsuit against Pfizer for providing kickbacks and trips packages to Caribbean or a sum of $2,000 as a donation for listening to the lectures about Baxter ( It is a training part for the transition of doctors to spokesperson for Pfizer ) it has been found guilty by and paid a sum of $325 million USD as a penalty https://drugstorenews.com/pharmacy/report-blue-cross-blue-shield-texas-sues-pfizer (06/11/2010) Blue Cross Blue Shield of Texas sues Pfizer- Alaric DeArment
  • 28. Shiley defective heart valves ▸ Bjork shiley owning to be as a subsidiary of Pfizer. Some of the heart valves produced by Bjork shiley found to be fractured and defective due to this around 300 to 500 people were passed away on receiving a defective valve and it was found by the US Department of Justice, and the company agreed to pay a sum of $10.75 million as a compensation https://www.ahajournals.org/doi/full/10.1161/CIRCULATIONAHA.104.511659 Risk of strut fracture of Björk-Shiley valves Y van der Graaf 1, F de Waard, L A van Herwerden, J Defauw PMID: 1346279 DOI: 10.1016/0140-6736(92)91328-6
  • 29. Royalty for Celebrex ▸ In 1990s, An enzyme discovered by Dr. Daniel L. Simmons in Birmingham University which led to the production of Celebrax ( celecoxib - Cox 2 inhibitor & NSAID, ▸ Dr. Simmons was originally, who was originally seeking 15% of the profit share (~ $9.7m) ▸ later (6yrs of verdict) agreed to pay a sum of 450 million dollars. Pfizer Settles Celebrex Lawsuit Intellectual Property: Drug firm logs a $450 million charge - Rick Mullin May 4, 2012 | A version of this story appeared in Volume 90, Issue 19
  • 30. The Trovafloxacin lawsuit ▸ In 1996, Outbreak of the measles and cholera and bacterial meningitis occurred in Nigeria ▸ On this scenario, contract research organization and Pfizer representatives departed to Nigeria. To conduct clinical trials, Out of 200 children who were administered with drug for clinical trials 50 were found passed away and others were found to develop mentally and physically deformities and ▸ Pfizer tried to bribe the Nigerian Attorney General Aondoakka to drop legal actions and on further investigation the company found to be guilty and agree to pay a sum of $30 million for the family of children's in the study. $30 million to support the healthcare initiatives in Kano and $10 million to cover the legal actions. Secret report surfaces showing that Pfizer was at fault in Nigerian drug tests- Jeanne Lenzer PMCID: PMC1471980 PMID: 16735322
  • 33. We make breathing the easiest thing on earth. The widest range of products against swine respiratory disease. Sheep's health has nothing to fear.
  • 34. Fake medicine online. Side effects may include: Get Real. Get a Prescription. (in million U.S. dollars)
  • 35.
  • 37. The Race to RSV vaccine Pfizer, jumping headfirst into the RSV vaccine race, kick-starts phase test ▸ Pfizer’s phase 3 clinical trial is set up to test the efficacy, immunogenicity, and safety of a single dose of its RSV vaccine, known as RSVpreF and will include around 30,000 older adults. ▸ In early data dropped rather quietly during second-quarter earnings just over a month back, and to little fanfare, Pfizer said a challenge study, where vaccines were given to 62 adults under 50 who were then intentionally infected with RSV to see if the shot worked, showed “100% observed efficacy against mild to moderate symptomatic infection resulting from RSV.” 37 https://www.fiercebiotech.com/biotech/pfizer- Ben Adams (Senior Editor)
  • 38. COLLABRATIONS ▸ PostEra enters a multi-year strategic partnership with Pfizer Inc. to advance machine learning for Drug Discovery ▸ Pfizer and LianBio Announce Strategic Collaboration to Expand Development of Novel Therapeutics in Greater China ▸ Pfizer’s investment in Homology is a testament to their enthusiasm for our PKU gene therapy and gene editing programs to treat ▸ people living with this disease,” stated Arthur Tzianabos, Ph.D., President and Chief Executive Officer of Homology Medicines 38 https://www.pfizer.com/partners
  • 39. COLLABRATIONS ▸ Vivet Therapeutics and Pfizer Inc. Enter into Manufacturing Agreement for Vivet’s ▸ Investigational Gene Therapy for Wilson Disease ▸ SpringWorks Therapeutics Announces Clinical Collaboration with Pfizer Inc. to ▸ Evaluate Nirogacestat in Combination with PF‐06863135 in Patients with Relapsed ▸ or Refractory Multiple Myeloma 39 https://www.pfizer.com/partners