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Pathema Community
     Outreach
Pathema Community
Pathema Workshops

• Clade-specific Pathema Workshops
      On JCVI Campus
  

         2 Days Hands On
       –
       – Live/Archived Webinar Broadcast
       – 4 Workshops Conducted, one per clade
      Organism Specific Meetings
  

         4 Hours Hands On
       –
       – 5 Workshops Conducted

• Prokaryotic Annotation & Analysis Course
      4 times each year at JCVI
  


      General annotation, not specific to an organism clade
  
Pathema Annotation Jamborees

• 3 day Jamborees held at JCVI
• First day teaches our annotation
  methodologies
• Follow up days allow the community to
  annotate with aid from our expert curators
• Excellent participation and feedback from
  our participants
Pathema Annotation Jamborees

• Entamoeba                  • Burkholderia
      Total Contributions:            Total Contributions:
                                 


      14 Participants                 9 Participants
                                 


      1022 Functional Names           502 Functional Names
                                 


      2019 GO Terms                   1480 GO Terms
                                 


      43 Gene Structures              86 Gene Structures
                                 


      285 Literature References       11 Literature References
                                 


      120 Paralogous Families         10 Burkholderia genomes
                                 




             4 Continued Collaborations
Presentations and Posters
• Last two years, focus on clade specific meetings
      ASM Biodefense
  


      Microbial Genomes
  


      International Conference on Microbial Genomics
  


      Genome Medicine and Environment (GME)
  


      International Biocuration Meeting
  


      Genome Informatics
  


      IBRCC
  


      The World Melioidosis Conference
  


      Workshop on Amoebiasis
  


      Functional Genomics of Gram+ Microorganisms
  


      Bacillus ACT Meeting
  
Collaborative Data Exchange

• Gene model and functional curation
      7 Bacillus anthracis strains
  


      1 Bacillus cereus strain
  


      1 Bacillus pumilus strain
  


      11 Clostridium botulinum strains
  


      4 Burkholderia pseudomallei strains
  




• Clostridium toxin curation
• Burkholderia mobile elements
Annotation Services

• JCVI’s prokaryotic annotation pipeline is
  available for any genome
• Offered for the past 7 years
• Currently processing 9 genomes a month
  with over 100 delivered so far in 2008
• Offered in conjunction with our 3 day class
• IGS also offers an annotation service
  called the IGS Annotation Engine
GenBank Annotation Updates

                            GenBank Annotation Submission Updates
                            db_xref   Product          Gene    Gene
     Genome project                             EC#
                              link     name           symbol   model
C.perfringens ATCC 13124     2899       16      11      9       0
C.botulinum E3 str Alaska
                             3264       65       4      3       0
E43
C.botulinum NCTC 2916        3747      153      14     14       0

C.botulinum A ATCC 1939 7    3598       68      13     14       0

E.histolytica HM-1:IMS S     8161      1381     18     16      1301

Total                       21669      1683     60     56      1301
Additional Outreach

•   Clade-specific Manuals & Tutorials
•   Glossary of Terms
•   Frequently Asked Questions
•   Integration of Informational Icons
•   24 hour Response Helpdesk
•   Publications and Presentation Page
•   Wiki Bug Reporting and Tracking System
Pathema Usage Statistics
    http://www.google.com/analytics/

                Visitor Overview:
                    16,500 unique users
                       2,700 unique users per month
                    25,800 visits
                    14,000 page hits
                Visitor Loyalty:
                    5:46 average time
                    10:00 direct users
                Traffic Sources:
                    38% search engines
                    32% direct traffic
                    30% referred sites
                Top Referral Sites:
                    Google, Wikipedia & NCBI

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Pathema Community Outreach

  • 1. Pathema Community Outreach
  • 3. Pathema Workshops • Clade-specific Pathema Workshops On JCVI Campus  2 Days Hands On – – Live/Archived Webinar Broadcast – 4 Workshops Conducted, one per clade Organism Specific Meetings  4 Hours Hands On – – 5 Workshops Conducted • Prokaryotic Annotation & Analysis Course 4 times each year at JCVI  General annotation, not specific to an organism clade 
  • 4. Pathema Annotation Jamborees • 3 day Jamborees held at JCVI • First day teaches our annotation methodologies • Follow up days allow the community to annotate with aid from our expert curators • Excellent participation and feedback from our participants
  • 5. Pathema Annotation Jamborees • Entamoeba • Burkholderia Total Contributions: Total Contributions:   14 Participants 9 Participants   1022 Functional Names 502 Functional Names   2019 GO Terms 1480 GO Terms   43 Gene Structures 86 Gene Structures   285 Literature References 11 Literature References   120 Paralogous Families 10 Burkholderia genomes   4 Continued Collaborations
  • 6. Presentations and Posters • Last two years, focus on clade specific meetings ASM Biodefense  Microbial Genomes  International Conference on Microbial Genomics  Genome Medicine and Environment (GME)  International Biocuration Meeting  Genome Informatics  IBRCC  The World Melioidosis Conference  Workshop on Amoebiasis  Functional Genomics of Gram+ Microorganisms  Bacillus ACT Meeting 
  • 7. Collaborative Data Exchange • Gene model and functional curation 7 Bacillus anthracis strains  1 Bacillus cereus strain  1 Bacillus pumilus strain  11 Clostridium botulinum strains  4 Burkholderia pseudomallei strains  • Clostridium toxin curation • Burkholderia mobile elements
  • 8. Annotation Services • JCVI’s prokaryotic annotation pipeline is available for any genome • Offered for the past 7 years • Currently processing 9 genomes a month with over 100 delivered so far in 2008 • Offered in conjunction with our 3 day class • IGS also offers an annotation service called the IGS Annotation Engine
  • 9. GenBank Annotation Updates GenBank Annotation Submission Updates db_xref Product Gene Gene Genome project EC# link name symbol model C.perfringens ATCC 13124 2899 16 11 9 0 C.botulinum E3 str Alaska 3264 65 4 3 0 E43 C.botulinum NCTC 2916 3747 153 14 14 0 C.botulinum A ATCC 1939 7 3598 68 13 14 0 E.histolytica HM-1:IMS S 8161 1381 18 16 1301 Total 21669 1683 60 56 1301
  • 10. Additional Outreach • Clade-specific Manuals & Tutorials • Glossary of Terms • Frequently Asked Questions • Integration of Informational Icons • 24 hour Response Helpdesk • Publications and Presentation Page • Wiki Bug Reporting and Tracking System
  • 11. Pathema Usage Statistics http://www.google.com/analytics/ Visitor Overview: 16,500 unique users 2,700 unique users per month 25,800 visits 14,000 page hits Visitor Loyalty: 5:46 average time 10:00 direct users Traffic Sources: 38% search engines 32% direct traffic 30% referred sites Top Referral Sites: Google, Wikipedia & NCBI