Oracle Service Bus can provide high availability and scalability for integration infrastructure. It supports multiple endpoints for a service, load balancing across endpoints, and dynamically adjusting routing if an endpoint fails. It also enables caching of service results to improve performance and handle spikes in requests. The document discusses how Oracle Service Bus was used to add a new credit validation vendor endpoint for load balancing. It also describes configuring a purchase order service to cache results to improve performance for repetitive requests.