This document discusses the benefits of Isotonix OPC-3, which contains powerful antioxidants called oligomeric proanthocyanidins (OPCs). It provides dosage recommendations, stating that the loading dose (taken for the first 7-30 days) should be higher than the maintenance dose. Taking a sufficient loading dose is important to achieve results, as not doing so could mean symptoms are not fully relieved. It describes how OPCs destroy free radicals, reduce inflammation, support collagen and circulation, balance blood sugar, reduce allergies and more. Live blood cell analysis images show how OPCs can improve cell health and reduce stickiness, aggregation and damage. Examples given show the importance of a sufficient loading dose period for improving

1. Isotonix OPC-­‐3 w/ Pycnogenol
OPCs (Oligomeric Proanthocyanidins)
A powerful antioxidant of plant derived bioflavonoids
maintain in your body is directly
proportional to how long you
Free radicals are molecules that have unpaired electrons
unstable, and reactive.
>90% of disease incidence involves free radical damage such
as cancer, heart diseases, osteoporosis, autoimmune,
radicals. Antioxidants neutralize free radicals and reduce our
risk of aging, sickness and disease.
20 times more powerful than vitamin C
50 times more powerful than vitamin E
One of the principal ingredients
that makes Isotonix® OPC-­‐3
probably the best antioxidant
cocktail in the marketplace is
Pycnogenol.
If you are going to add supplemental nutrition, it is
important that it is delivered in an isotonic state.
Isotonix supplements offer a 95-­‐98% absorption rate
within minutes, delivered to small intestine with no
dilution.
Powerful antioxidant destroys free radicals
that cause disease & aging
Natural anti-­‐inflammatory reduces pain
without unwanted side effects
Selective binding to collagen . Improves skin &
promote internal healing
Promotes normal production of nitric oxide
which improves circulation and support
normal blood pressure
Clinically studied to help balance sugars
Natural anti-­‐histamine can reduce symptoms
of all types of allergies
OPC Before & After
Why do we get sick?
Not all supplements are created the same
Basic Pharmacologic Activities
Make a difference with OPC-­‐3
Isotonix
Undigested Pills
in the colon www.WellnessDrWen.com

2. OPC-3 Recommended Serving Dosage and Healing Reactions
*For best results, take on an empty stomach and wait 10-15 minutes before ingesting food or liquids.
*Loading Dose For the first seven days, if no pre-existing conditions, take one white capful (one dose) per every
75 pounds of body weight (example: if you weigh between 75-150 pounds, take two doses; between 151-225
pounds, take three doses; between 226-300 pounds, take four doses). Add one capful per 75-pound for each
additional health issues. OPC-3 is non-toxic. You can increase dosage if necessary (for instance, for relief of
arthritic pain, take three doses for a 75-150 lb. person; if symptoms are not totally relieved, increase to four to six
doses). For those that have physical challenges, maintain the loading dose for up to thirty days before shifting to
the maintenance dose.
*Put one white capful of OPC-3 in clear cup and add water to line stir and drink (NOTE when taking more than
one dose, you can use another container and add 2 ounces of water per white capful of OPC-3).
*Maintenance Dose Starting on the eighth day and continuing each day thereafter take one dose.
one dose = one white capful Contains 75 mg of Active OPC and 50 mg of Bioflavonoids which are additional
sources of antioxidant support.
OPC Loading and Maintenance Dose
The loading dose of OPC-3 is the most crucial component in achieving successful results with this incredible
product. If you have customers who have not achieved desired results, check to make sure they completed the
loading dose amount as listed below. If the answer is yes, then, they need to try extending the loading dose time.
At a minimum, the loading dose should continue for ten days. It may be necessary to continue it for up to three
months, depending on the severity of the conditions they wish to relieve. We are achieving improved results when
lth.
The chart below is for determining the daily loading dose as well as the maintenance dose for people with no pre-
existing health issues. Please add one cap for each additional health issue per 75 lb. It is meant to be used as a
guideline only.
Daily Daily
Weight Loading Dose Maintenance Dose
75 - 150 lbs. 2 Caps of OPC-3 1 Cap of OPC-3
150 - 225 lbs. 3 Caps of OPC-3 2 Cap of OPC-3
225 - 300 lbs. 4 Caps of OPC-3 3 Caps of OPC-3
300 - 375 lbs. 5 Caps of OPC-3 3 Caps of OPC-3
375 - 450 lbs. 6 Caps of OPC-3 4 Caps of OPC-3
OPC-3 & Healing Reactions or Detox
This reaction occurs when the body tries to eliminate toxins at a faster rate than they can be properly disposed of.
The more toxic one's bodily systems are, the more severe the detoxification, or healing crisis. It is characterized by
a temporary increase in symptoms during the cleansing or detox process which may be mild or severe. You may
feel worse. But these reactions are instead signs that the treatment is working and that your body is going through
the process of cleaning itself of impurities, toxins and imbalances.
Such reactions are temporary and can occur immediately -- or within several days, or even several weeks, of a
detox. Symptoms usually pass within 1-3 days, but on rare occasions can last several weeks. If you are suffering
from a major illness, the symptoms you experience during the healing crisis may be identical to the disease itself.
Sometimes discomfort during the healing crisis is of greater intensity than when you were developing the chronic
disease. This may explain why there may be a brief flare-up in one's condition. Often the crisis will come after you
feel your very best. With a more serious condition there may be many small crises to go through before the final
one is possible.
Drink plenty of fresh water (especially water), juices, and herbal teas to flush the body of toxins. If you are feeling
fatigued, or sleepy, your body is talking to you, and telling you to rest. Be kind to yourself, and get the rest that you
need.

3. What Live Blood Cell Analysis Can Show You
The pictures provided by the Plant Enzyme Research Consortium Inc. for informational purposes only.
Photos were taken using a dark field phase contrast microscope
Undigested Proteins, Vitamins and Mineral Deficiencies
Normal Red Blood Cell (RBCs)
The circulatory system is the means by which oxygen, nutrients, antibodies, and hormones are
transported to the cells to keep them alive and functioning. This is how your blood looks when you
are experiencing optimum health. The Erythrocytes (cells) are round and separated and move
through the capillaries very easily. The average size of healthy RBC is 7.2 microns. The average
number of red blood cells in the human body is 25 trillion. The average red blood cell lives 120
days. Your blood makes a complete circuit in your body every 30 seconds.
Protein Linkage
This condition is the first sign of cell stickiness and may progress into rouleau if not corrected.
Protein linkage is a sign that excessive protein is being consumed or the protein is not being
digested completely. As the cells start sticking together it becomes harder for your heart to push the
blood through your veins and arteries.
Rouleau
When the blood gets to this condition the amount of oxygen that can be transported is severely
diminished. This condition is caused by high fat and protein diets and high acidity. It results in poor
circulation of the blood, and therefore decreases the amount of oxygen and nutrients available for
your body to use. Your blood will look like this if you drink one soda and will stay that way for at
least two hours. Because your cells are not getting oxygen they need, you may experience fatigue,
have poor digestion, and the possibility of skin disorders.
Erythrocyte Aggregation
This condition is one step worse than rouleau. This is often seen in people with degenerative
diseases. This is caused by undigested fats and proteins and high acidity. Degeneration of tissue
follows low oxygen and acidity. This condition can also precede a blood clot which can cause a
stroke or heart attack.
Poikilocytosis
Red blood cells who's cell membrane wall has been damaged on a molecular level. Many agents
may contribute to this damage including but not limited to, carcinogenic agents, preservatives,
chemicals, or other outside agents absorbed by the body. These free radical possessing agents
make the cell incapable of effectively delivering nutrients and oxygen.
Microcyte
These are small red blood cells having a diameter of less than 5 microns. These cells have less
hemoglobin than normal cells and are often seen in people with anemia.
Macrocyte
These cells are greater than 10 microns in size. Macrocytes are often seen in people with hemolytic
anemia, food allergies, and poor absorption. Can be caused by enzyme deficiency, folic acid and B12
deficiency.
Anisocytosis
In this condition there are variations in the size of the cells. This is mostly seen in people with low levels
of the vitamins B12 and folic acid and the mineral iron.
Target Cell
These red blood cells are deficient in iron and therefore hemoglobin, which is the part that carries oxygen.
The symptoms produced in the body are tiredness, poor digestion, and anemia.
Hemolysis
This is the destruction of the red blood cell. It can be caused by bacterial infection or toxins introduced
into the blood stream. The hemoglobin goes out of the cells interior and diffuses into the plasma. Can be
caused by hypotonic fluid injected intravenously. Also caused by malnutrition within the cell causing it to
die prematurely.
www.WellnessDrWen.com

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6. Significance of Adequate OPC-3 Loading Dose
1 2 caps for 2 years 6 caps for 12 days1-2 caps for 2 years 6 caps for 12 days
Lack of energy; extremely drowsy during driving.
Has Been taking 1 2 caps of OPC 3 for 2 years
12 days after taking 6 caps of OPC-3 for 12 days.
W ll k d i d i i
6/4/2010 6/12/2010
Has Been taking 1-2 caps of OPC-3 for 2 years. Well awake during driving.
4 caps OPC-3for 13 days 1 cap Resveratrol
+
Severe Allergies
4 caps OPC-3
for 3 more days
7-year-old with allergies 4 caps OPC-3for 13 days
Allergies greatly improved
4 caps OPC-3 & 1 cap Resveratrol for
additional 3 days
6/17/2010 6/30/2010 7/3/2010